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Appendix 11B - Management of Patients with Dry Eyes Patient presents with dry eyes Mild dry eyes symptoms Treat as per algorithm level 1 and monitor Moderate dry eye symptoms Refer to optometrist for slit eye examination Moderate symptoms OR signs Treat as per algorithm level 2 and monitor Severe symptoms AND signs * Refer to ophthalmology Author: Dr. P. Kearns, Shirley Miller, Ophthalmology Version No:1 Date: Feb. 2015 Review Date: Feb. 2017 Approved on behalf of NHS Fife by the Fife Area Drugs & Therapeutics Committee Date: April 2015 Treatment for Dry Eyes Mild Dry Eye: Treatment by GP or Optometrist Mild, adequately controlled with level 1 treatment as below. Nil significant Moderate Dry Eye: Refer to Optometrist for Assessment Severe Dry Eye: Refer to Hospital Inadequate symptomatic relief on “mild dry eye treatment” Impaired function None Severe impairment e.g. only able to read for short periods, has to interrupt TV viewing to “rest eyes” Treatment Level 1 Treatment: Level 2 Treatment: Step 1 ® Carbomer Gel (Clinitas 0.2%) or Polyvinyl alcohol drops (Liquifilm ® ® Tears ) + VitA-POS eye ointment. ® Increase usage of VitA-POS to one or two applications alternate eyes during 3 the day . Step 2 Change prescription to preservative free* eye drops –Carmellose sodium ® (Carmize P/F). To be used as required. Step 3 If not effective/not tolerated introduce ® sodium hyaluronate (Blink Intensive Tears) eye drops. Inadequate symptomatic relief on “moderate dry eye treatment” Corneal epithelial defects. Mucofilaments adhering to the cornea, marked conjunctival hyperaemia, absent tear 4 production Severe impairment of daily function. Decreased visual acuity not due to other ocular pathology Level 3 Treatment: Symptoms Signs st 1 line: Hypromellose eye drops 0.3% 4-6 x daily nd 2 line: Carbomer Gel ® (Clinitas 0.2%) or Polyvinyl alcohol drops ® (Liquifilm Tears ) 3 – 4 x daily + ® VitA-POS eye ointment at night. 1 Significant SPE , perhaps confluent in 2 places, rapid TFBUT (<5 sec.), significant mucofilament production, conjunctival hyperaemia Refer to Ophthalmology as “severe dry eye”** Notes: *Patients using standard eye drops more than 6x daily are more likely to develop corneal toxicity and should use preservative free preparations instead. ** Patients should only be referred to ophthalmology if patient has at least some of the signs as described for severe dry eye. Severe symptoms or functional impairment without signs do not warrant referral. These patients pose a challenge and require counselling regarding the chronic nature of their condition, advice regarding alternative ocular lubricants and supportive measures such as wearing goggles and treating associated blepharitis. The optometrist is best placed to provide such support and advice. (It is often a case of trial and error to find which preparation gives the greatest relief for an individual patient). See Fife Formulary for alternative formulary choices. Intercurrent bleparitis needs to be treated Important to emphasise to patient that: - this is a chronic condition, most, not all, patients get some, not complete, relief from treatment - treatment is supportive, not curative; if treatment is stopped, symptoms will come back - most patients with dry eyes experience remission; often after a year or two, troublesome symptoms may improve significantly It is important to review patient regularly to gauge response to treatment; there is no point continuing hourly carmellose sodium (Carmize®) on repeat if it is no more effective than hypromellose or carbomer gel. It is also important for the prescriber to recognise that there is no point in referring a patient with “moderately severe dry eyes” who has failed to respond to Level 2 treatment; this patient is one of those unfortunate individuals for whom there is little additional treatment options. Patients should be advised to adhere to treatment or try alternative formulations. 1 SPE: superficial punctuate erosions, identified after instillation of fluorescein dye TFBUT: tearfilm break-up time, normally > 10 seconds VitA-POS® gives very effective symptomatic relief but will blur vision significantly 4 Shirmer’s Test result < 2mm in 3 minutes 2 3 Author: Dr. P. Kearns, Shirley Miller, Ophthalmology Version No:1 Date: Feb. 2015 Review Date: Feb. 2017 Approved on behalf of NHS Fife by the Fife Area Drugs & Therapeutics Committee Date: April 2015