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Functions  Digestion – breakdown  Absorption Organization  Alimentary Canal Gastrointestinal (GI) Tract   Mouth to anus 30 feet long Organization (cont’d)  Accessory  Found Organs either within the alimentary canal or outside it and communicate with it by way of ducts  Teeth, salivary glands, tongue, pancreas, liver, and gallbladder Mucous Membranes  System lined with mucous membrane  Kept moist for lubrication and absorption Tunics  Walls of alimentary canal from esophagus to large intestine lined with 4 basic layers (tunics) Tunics (cont’d)   Mucosa  Innermost layer lines lumen of organ Submucosa  Nerves, blood vessels, glands Tunics (cont’d)  Muscularis externa Smooth muscle  Inner circular layer  Outer longitudinal layer  Combined contraction causes peristalsis  Tunics (cont’d)  Serosa Outermost  Visceral peritoneum  Continuous w/ parietal peritoneum  Mesentery  Greater and lesser omentum  Digestive Processes Ingestion  Propulsion    Peristalsis Segmentation Digestive Processes (cont’d)  Mechanical  Chewing, digestion churning, etc.  Prepares food for further breakdown by enzymes Digestive Processes (cont’d)  Chemical digestion  Large food molecules broken down to building blocks by enzymes Carbohydrates  monosaccharides  Proteins  amino acids  Lipids  fatty acids and glycerol   Absorption  Elimination - Defecation Mouth    Lips and cheeks Palate – roof Tongue – floor  Forms bolus (ball) of food  Attached to hyoid bone and styloid process of skull  Frenulum Mouth (cont’d)  Teeth  Deciduous (baby) teeth  Permanent teeth  Digestive  Food processes of mouth ingestion  Mechanical – mastication (chewing)  Chemical - starches Salivary Glands Parotid glands  Near ears  Mumps  Submandibular gland  Inside jaw  Sublingual gland  Under tongue  Digestive processes  Chemical breakdown of starches  Pharynx/Esophagus Pharynx  Esophagus     Gullet Conducts food to the stomach Digestive processes  Food propulsion  Swallowing – deglutition  Peristalsis Stomach  Cardioesophageal  Cardiac  Fundus region sphincter Stomach (cont’d)  Body  Pylorus  Pyloric sphincter or valve Stomach (cont’d)  When full, can hold about 4L of food  When empty, collapses inward on itself  Large folds – rugae Stomach (cont’d)  Walls have 3rd muscle layer – oblique  Allows food churning and mixing of Stomach (cont’d)  Gastric glands produce:  HCl, pepsin, rennin, mucus (protects stomach from digesting itself), gastrin, and intrinsic factor  Chyme – semifluid; passes on to the sm. intestine Stomach (cont’d)  Digestive processes  Mechanical – churning  Chemical – proteins  Propulsion - peristalsis Small Intestine  Major digestive organ   6m long Three subdivisions:  Duodenum  Jejunum  Ileum Small Intestine (cont’d)  Microvilli, villi, and circular folds  Increase surface area for enhanced absorption Small Intestine (cont’d)  Pancreatic duodenum juice and bile enter Small Intestine (cont’d)  Digestive  Food processes digestion (chemical) of carbohydrates, proteins and lipids completed here  Absorption of water and end products of digestion also completed here  Mechanical – bile – emulsifies  Propulsion - peristalsis Large Intestine  Subdivisions      Cecum Appendix Colon Rectum Anal Canal Large Intestine (cont’d)  Digestive processes  Food breakdown  Bacteria metabolize remaining nutrients to produce vitamins (K & some B)  Reabsorbs these vitamins, bile salts, and water  Propulsion  Peristalsis and mass movements  Elimination – defecation remainder of undigested food– feces Pancreas  Pancreatic  Contains juice enzymes that break down all categories of food  Secreted into the duodenum in an alkaline fluid (neutralizes acidic chyme) Liver  Largest gland of body  Produces bile  Emulsifies fat  Enters duodenum through bile duct Gallbladder  When food digestion is not occurring, bile backs up into gallbladder to be stored Homeostatic Imbalances  Appendicitis    Gallstones   Inflammation of appendix If ruptures, spread infection throughout peritoneal cavity – peritonitis – life-threatening If bile stored too long in gallbladder or too much water is removed – cholesterol crystallizes Heartburn  Cardioesophageal sphincter fails to close tightly – gastric juices backs up into esophagus Homeostatic Imbalances (cont’d)  Hiatal Hernia    Superior part of stomach protrudes slightly above diaphragm Gastric juice flows into unprotected esophagus Ulcers    Erosion of mucosa of any part of GI tract exposed to secretions of stomach Duodenal ulcer 3x more common than gastric ulcer Bacteria Helicobactor pylori now believed to be major cause of ulcers Homeostatic Imbalances (cont’d)  Emesis  Vomiting  Like a reverse peristalsis  Caused by irritation of stomach or disturbance of equilibrium  Diverticulitis  Diverticula (mucosa protrusions thru colon walls) become inflamed.  May be caused by chronic constipation and low-fiber diet Homeostatic Imbalances (cont’d)  Diarrhea   Constipation   Food rushed thru large intestines before water can be absorbed Food remains in large intestine for extended time – too much water is absorbed Hepatitis    Inflammation and death of liver tissue Usually caused by viruses May be caused by chemical toxins Homeostatic Imbalances (cont’d)  Colitis  Inflammation of colon and rectum  May be chronic (usually inherited) or acute (caused by irritation of bowel due to diet or infection) Homeostatic Imbalances (cont’d)  Cancer  Stomach and pancreatic Highly metastatic  Usually fatal   Colon Common  Fatal if not treated early