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CH107 Mock Exam 2
Name: ______________________________
100 pts. 1-34 2pts, 35-40 8pts. (choose 4 of 6)
1) What are the components of DNA?
A) Ribonucleic acid,
B) Amino group, phosphate group, pentose sugar
C) Sugar-phosphate backbone
D) fructose sugar, nitrogen ring
E) Nitrogen containing ring, pentose sugar, phosphate group
2) What are the 3 types of RNA?
A) Transfer, Messenger, Ribose
B) Transfer, Meaningless, Ribosomal
C) Translational, Messenger, Ribosomal
D) Transfer, Messenger, Ribosomal
E) Translational, Messenger, Ribosomal
3) Which of the following is a purine base?
A) Uracil
B) Adenine
C) Thymine
D) Cysteine
E) Orotate
4)
A)
B)
C)
D)
E)
____ brings specific amino acids to the ribosome
rRNA
mRNA
tRNA
sRNA
rrRNA
5) The _____ is the primary structure of a nucleic acid
A) Nucleotide
B) Peptide
C) Genetic sequence
D) DNA
E) RNA
6) Which of the following bond types are found in DNA?
A) Phosphodiester
B) Glycosidic
C) Hydrogen bonds
D) A and C
E) All of the above
7) Which of the following is found in DNA?
A) Cytoseine
B) Adenosine
CH107 Mock Exam 2
Name: ______________________________
C) Uracil
D) All of the above
E) A and B
8) In _____ the parent strands of DNA each form one strand of two new daughter
strands.
A) Semi-conservative replication
B) Conservative replication
C) Translation
D) RNA translation
E) A and B
9) DNA replication occurs in the _____ by ______.
A) Nucleus, semi-conservative replication
B) Ribosome, semi-conservative replication
C) Nucleus, conservative replication
D) Ribosome, conservative replication
E) A and C
10) A ______ can produce energy for replication by breaking one phosphate bond.
A) AMP
B) ATP
C) Triphosphate nucleotide
D) A and B
E) B and C
11) The lagging strand is synthesized in fragments, called ______.
A) Okazawa fragments
B) Okazaki fragments
C) Lagging fragments
D) Okanawa fragments
E) None of the above
12) ______ breaks the hydrogen bonds connecting 2 strands of DNA during replication.
A) Helicase
B) DNA polymerase
C) DNA ligase
D) Topoisomerase
E) DNA primase
13) ______ unwinds the DNA during replication.
A) Helicase
B) DNA primase
C) DNA polymerase
D) DNA ligase
E) Topoisomerase
CH107 Mock Exam 2
Name: ______________________________
14) _____ connects the Okazaki fragments during replication.
A) Helicase
B) DNA polymerase
C) DNA ligase
D) Topoisomerase
E) DNA primase
15) ______ attaches a base and forms the phosphodiester bond.
A) Helicase
B) DNA polymerase
C) DNA ligase
D) Topoisomerase
E) DNA primase
16) _____ is the process of forming mRNA.
A) Transcription
B) Translation
C) RNA sequencing
D) Transmutation
E) A and B
17) _____ helps form the structure of the ribosome
A) mRNA
B) tRNA
C) rRNA
D) sRNA
E) rrRNA
18) List the following steps in order.
i)
DNA double helix is reformed
ii)
mRNA sequence is synthesized from the DNA template strand
iii)
mRNA leaves the nucleus and attaches to ribosome
iv)
DNA double helix is unwound
A) i,ii, iii,iv
B) iv, ii,iii,i
C) iv,ii,i,iii
D) ii,iv,i,iii
E) ii,iv,iii,i
19) Which of the following about transcription is FALSE?
A) It proceeds in the 5’ to 3’ direction for both leading and lagging strand
B) Differs from DNA replication in that only one strand is copied.
C) Transcription is slower, and more error prone, than replication.
D) A and C
E) All true
CH107 Mock Exam 2
Name: ______________________________
20) The codon UGA codes for which amino acid?
A) Cys
B) Trp
C) Tyr
D) None
E) Methionine
21) A ribosome consists of how many subunits?
A) 1 subunit
B) 2 –one large and one small subunit
C) 3 – 2 small subunits, 1 large subunit
D) 4 – heterodimer
E) 2 – both large subunits
22) Transfer RNA binds to the mRNA codon with a(n) _____
A) Anticodon
B) Complimentary codon
C) AUG
D) Hydrogen bond
E) specific amino acid
23) Stop codons bind to proteins called _____
A) Anticodons
B) tRNA units
C) release factors
D) translation factors
E) transcription factors
24) List which steps make up translation and in the correct chronologic order.
I) Elongation
II) Initiation
III) Release
IV) Termination
V) Attachment
A) V,II,I,IV
B) I,II,III,IV,V
C) V,I,II,IV,
D) II,I,IV
E) II,I,III
25) Who is responsible for the discovery of DNA (double helix structure)?
A) Watson and Crick
B) Darwin and Mendel
C) Gregorian Mendel
D) Einstein
E) Nikola Tesla  coolest guy ever
CH107 Mock Exam 2
Name: ______________________________
26) Which of the follow is a form of Post Translational Modification?
A) Amidation
B) Acetylation
C) Phosphorylation
D) B and C
E) All of the above
27) Which of the following is a result of a chromosomal mutation affecting hemoglobin?
A) Huntington’s Disease
B) Sickle Cell Anemia
C) Hemophilia
D) Cystic fibrosis
E) Galactosemia
28) Which of the following is an example of silent mutation?
A) AAA AAU
B) UGC  UGA
C) UUU  UUC
D) GGU  GGG
E) CCU  CCA
29) A frameshift mutation is caused by ____.
A) 1 or 2 bases being added
B) 1 or 2 bases being removed
C) 3n bases being added
D) 3n bases being removed
E) A and B
30) ____ is the most common genetic disease and is caused by a deletion.
A) Down’s Syndrom
B) Sickle Cell Anemia
C) Cystic Fibrosis
D) Klinefelter’s Syndrom
E) Autism
31) Given the nucleotide, what peptide results?
5’ TACTTACGCACT 3’
A) Met-Asn-Ala
B) Stop-Leu-Arg-Thr
C) Thr-Arg-Leu
D) Ala-Asn-Met
E) AUGAAUGCGUGA
32) Given the following peptide what is a possible nucleotide sequence?
Met-Phe-Tyr-Ser
A) AUGUUUUACUCCUGA
CH107 Mock Exam 2
B)
C)
D)
E)
Name: ______________________________
TACAAATGAGGACT
AUGUUUACUCC
TACAAATGAGG
UGAAUGUUUUACUCCUGA
33) Given the following mRNA sequence, what is the original nucleotide sequence.
UUCGCGAGAUCGAGU
A) TTCGCGAGATCGAGT
B) GGATATCTCGATCTG
C) CCTATAGAGCTAGAC
D) AAGCGCTCTAGCTCA
Given the following DNA strand:
5’-ATG-CAT-GCT-TTA-CAA-GAT-TGA-3’
1a. Write the peptide coded by the mRNA strand.
1b. Write another mRNA strand which codes for the same peptide, but has four point mutations.
1c. If, in the original strand, T9 is replaced by a G and C4 is replaced by an A, what peptide is
produced?
1e. If, in the original strand, T10,T11 and G16 are deleted, what peptide is produced?
CH107 Mock Exam 2
Name: ______________________________
1f. If, in the original strand, T10,T11, and A12 are deleted, what peptide is produced?
2. Draw double stranded DNA. Include 4 nucleotides in each strand (the double strand should
have 8 nucleotides total). Include the correct pentose structure and phosphate linkages. You
do not have to draw specific nucleotides but signify the specific base via letter abbreviations (ie.
A,T,C,G).
3. Below is the structure for Adenine. Draw the structure for ATP. If catabolic metabolism
occurs, draw the product.