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BIOL2120 CELL BIOLOGY by Lawrence Chiu, PhD Email: [email protected] 2020-21 (1st Term) Mon 8:30 - 11:15 https://cuhk.zoom.us/j/98676874683 Expected Learning Outcomes • To recognize the structures and functions of some basic components of a eukaryotic cell; • To explain how normal cells are maintained by regulating their division and death; and • To apply the basic knowledge of cell biology in understanding and treatment of diseases, which are caused by changes or losses in cell functions. Course Content Topic 1. Introduction - Cell Biology & Microscopy 2. Membranes - Their Chemistry, Structure and Functions 3. Transport across Membrane - Overcoming the Permeability Barrier 4. The Endomembrane System - Transport within a Eukaryotic Cell Mid-term Online Quiz [05/10] 5. Signal Transduction Mechanisms - Their Messengers and Receptors 6. Cytoskeleton - Structures for Maintaining Cell Shape and Internal Organization 7. Cell Cycle - The Events of Cell Growth and Division 8. Apoptosis - The Programme to Cell Death 9. Clinic Applications in Cell Biology Final Online Quiz [07/12] Assessments 1. Meetings and Discussions with Senior Student Tutors (10%) 2. Midterm Problem Set (10%) and Online Quiz (20%) (on topics 1-4)* [05/10] 3. Final Problem Set (25%) and Online Quiz (35%) (on topics 5-9)* [07/12] * May be replaced by face-to-face exams if the COVID-19 pandemic stabilizes References Core • Jeff Hardin, Gregory Bertoni, Lewis J. Kleinsmith and Wayne M. Becker. Becker’s World of the Cell, 9th Edition, Boston: Benjamin Cummings. Supplementary • Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts and Peter Walter. Molecular Biology of the Cell, 6th Edition, NY: Garland Science. • Selected videos on the web Grade Descriptors A / ADemonstrates excellent understanding of knowledge, exceptionally insightful approach in handling problems, and fluent expression of argument in cell biology, founded on careful reading and critical evaluation of relevant materials. B+ / B / BDemonstrates a good to very good grasp of knowledge, generally persuasive approach in handling problems and clear expression of argument in cell biology, with evidence of careful reading and evaluation of relevant materials. C+ / C / CDemonstrates basic understanding of knowledge but with some errors and vague approach in handling problems and expression of argument in cell biology, with evidence of reading of relevant materials. D+ / D Demonstrates minimal understanding of knowledge and capability in handling problems and expression of argument in cell biology, with little evidence of reading of relevant materials. F Demonstrates inadequate understanding of knowledge and serious mistakes in handling problems in cell biology, without evidence of reading of relevant materials. ** Students submitting assignment done by third party is also a serious misconduct and regarded as fraud or academic dishonesty. The updated Procedures are available at the University’s website “Honesty in Academic Work: A Guide for Students and Teachers” (http://www.cuhk.edu.hk/policy/academichonesty/). REMINDER: Students please note the aforementioned marking scheme, grade descriptors, academic honesty principle and the university penalty guideline are all applicable to this course. General university regulations are available on line: http://www.res.cuhk.edu.hk/en-gb/general-information/university-regulations; please check them out.