Download CHARAK INSTITUTE OF PHARMACY Subject: Organic Chemistry

CHARAK INSTITUTE OF PHARMACY
Subject: Organic Chemistry-I
MCQ
Sub.Code: PY-114
1. The analgesic action of aspirin is removed, if
a. Carboxyl group is removed
b. Acetoxy group is removed
c. Carboxyl group is not attached on ortho position
d. All of the above
-------------------2. Diastereoisomerism and enantiomorphism is shown in
a. Ephedrine and pseudoephedrine
b. D and L-ephedrine
c. Ephedrine & pseudoephedrine and D & L-ephedrine respectively
d. D & L-ephedrine and Ephedrine & pseudoephedrine respectively
-------------------3. Caffeine is presented as a/an
a. Purine derivative
b. Pyrimidine derivative
c. Imidazole derivative
d. both b and c
-------------------4. A group that can donate an electron pair is
a. Bronsted acid
b. Bronsted base
c. Lewis acid
d. Lewis base
-------------------5. Hendersen-Hasselbalch equation is represented by
a. Ka = [A][H+]/[HA]
b. pKa + pKb = 14
c. pKa = pH + log [HA]/[A-]
d. both a and c
-------------------6. Which of the following is through space-effects on polarizability due to electronegativity
differences?
a. Field effect
b. Inductive effect
c. Resonance effect
d. Polarizability
-------------------7. Which of the following is the ease of distortion of the electron cloud?
a. Field effect
b. Inductive effect
c. Resonance effect
d. Polarizability
-------------------8. Which of the following occurs as a result of electronegativity differences?
a. Field effect
b. Inductive effect
c. Resonance effect
d. None of the above
-------------------9. Which of the following involves the actual movement of electrons through a pie-bond system?
a. Field effect
b. Inductive effect
c. Resonance effect
d. None of the above
-------------------10. The movement of electrons through a conjugated system allows for charges to be dispersed
over several atoms. This phenomenon is
a. Localization
b. Delocalization
c. Polarization
d. Depolarization
-------------------11. Which of the following is less influenced by distance?
a. Field effect
b. Inductive effect
c. Resonance effect
d. both a and c
-------------------12. Which of the following is a carbonyl based group?
a. esters
b. nitroc. alcohols
d. ethers
--------------------
13. Which of the following shows electron withdrawing groups?
a. phenyl
b. ethers
c. amines
d. alkyl groups
-------------------14. Which of the following shows electron donating group?
a. amides
b. esters
c. ketones
d. amines
-------------------15. Which of the following has minimum pKa value or maximum acidic strength?
a. imide
b. sulphonamide
c. N-arylsulfonamide
d. sulfonimide
-------------------16. sigma-bonding electrons, especially those from C-H bonds can be donated in a process
known as
a. conjugation
b. hyperconjugation
c. polarization
d. depolarization
-------------------17. Which of the following has neutral pKa value?
a. Water
b. Ether
c. Amide
d. All of the above
-------------------Answers to multiple choice questions (MCQs) in Organic Pharmaceutical Chemistry
1. D 2. C 3. A 4. D 5. C 6. A 7. D 8. B 9. C 10. B 11. C 12. A 13. A 14. D 15. D 16. B 17. D
MCQ 18. General formula for alcohols is
1.
2.
3.
4.
CnH2n
CnH2n+1
Cn H
CH3
B
MCQ 19. Removal of after molecule in a reaction is termed as
1.
2.
3.
4.
hydrolysis
dehydration
hydrogenation
halogenations
B
MCQ 20. Ethanol is made undrinkable by addition of
1.
2.
3.
4.
sugar cane
yeast
methanol
methane
C
MCQ21. Reaction which involves breakage of O-H bond in alcohols is
1.
2.
3.
4.
hydrolysis
esterfication
esterlytic
hydration
B
MCQ 22. Methylated spirits contain an estimated percentage 90%
1.
2.
3.
4.
methyl
methanol
ethanol
all of them
C
MCQ 23. Ester's smell is
1.
2.
3.
4.
sweet
fruity
pungent
both A and B
D
MCQ 24. On heating esters with an acid or base it will be
1.
2.
3.
4.
deployed
hydrolyzed
prototyped
homolysed
B
MCQ 25. Reaction between ethanol and hydrogen bromide will give
1.
2.
3.
4.
bromide
bromoethane
bromoethane
bromoethanol
B
MCQ26. After reaction if excess ethanol is evaporated white solid crystals will be left of
1.
2.
3.
4.
sodium chloride
sodium mangnate
sodium ethoxide
sodium hydroxide
C
MCQ 27. Under mild conditions, tertiary alcohols give
1.
2.
3.
4.
extreme reaction
no reaction
mild reaction
secondary alcohols
B
MCQ 28. Fuel gasohol is mixture of
1.
2.
3.
4.
ethanol
petrol
methanol
both A and B
D
MCQ 29. Methylated spirit use to satiate their desire instead of alcohol and end up in getting
1.
2.
3.
4.
blindness
death
both A and B
lung cancer
C
MCQ 30. Alcohols reacts with oxygen to form
1.
2.
3.
4.
water
carbon dioxide
carbon monoxide
carbon trioxide
C
MCQ 31. Brazil have fewer oil reserves that's why they can grow lot of sugar cane to produce
1.
2.
3.
4.
alcohol
ethanol
glucose
sugar
B
MCQ 32. Organic molecules containing hydroxyl group are called
1.
2.
3.
4.
esters
alcohols
aldehydes
ethane
B
MCQ 33. Ethanol is biofuel and are known as
1.
2.
3.
4.
carbon neutral
hydrogen neutral
oxygen neutral
all of them
A
MCQ 34. Propan-2-ol will get oxidized to give
1.
2.
3.
4.
aldehyde
ketone
alcohol
carbonyl
B
MCQ 35. 2 methyl-2 propan-2-ol is an example of
1.
2.
3.
4.
primary alcohol
secondary alcohol
tertiary alcohol
quaternary alcohol
C
MCQ 36. Organic molecules with similar relative molecular mass have alcohols (CnH2n+1OH)
bearing high
1.
2.
3.
4.
boiling point
polarity
volatility
Sublimation point
A
MCQ 37. When hydroxyl group is attached to carbon atom bonded to two other carbon atoms,
alcohol formed is
1.
2.
3.
4.
primary alcohol
secondary alcohol
tertiary alcohol
quaternary alcohol
B
MCQ 38. Alcohol (CnH2n+1OH) with lowest molecular mass at room temperature is
1.
2.
3.
4.
solid
liquid
gas
vapor
B
MCQ 39. Blue cheese have smell because of ketone
1.
2.
3.
4.
heptan-2-one
heptan-3-one
heptan-2-ol
hexa-2-one
A
MCQ 40. Further addition of ethanol will lead to different product as
1.
2.
3.
4.
ethanoic acid
ketones
benzaldehyde
all of them
A
MCQ 41. Carbonyl group in aldehyde is
1.
2.
3.
4.
C=O
C-O
CO
CHO
A
MCQ 42. During a reaction, formation of mirror inside tube is due to.
1.
2.
3.
4.
silver ions
silver atoms
silver compounds
silver nitrate
B
MCQ 43. Oxidation of primary alcohols give
1.
2.
3.
4.
aldehydes
ketones
both A and B
alcohols
A
MCQ 44. Chemical reaction between carbonyl compounds and DNPH is example of
1.
2.
3.
4.
condensation reaction
substitution reaction
addition reaction
elimination reaction
A
MCQ 45. If ketones are not oxidized, then upon heating Fehling's solution remains
1.
2.
3.
4.
white
blue
unchanged
both B and C
D
MCQ 46. CH3CH2CH2CH2CHO is formula for
1.
2.
3.
4.
methanol
propanal
butanal
pentanal
D
MCQ 47. Reduction reactions of carbonyl compounds is known to be
1.
2.
3.
4.
Nucleophilic addition
Nucleophilic substitution
addition reaction
elimination reaction
A
MCQ 48. Ketones react with reducing agent to make
1.
2.
3.
4.
primary alcohols
secondary alcohol
tertiary alcohol
all of them
B
MCQ 49. In carbonyl group Oxygen atom has high electronegativity which make it
1.
2.
3.
4.
stable
non-polar
polarized
unstable
C
MCQ 50. Silver ions Ag+ act as
1.
2.
3.
4.
reducing agent
oxidizing agent
catalyst
both A and B
B
MCQ 51. Hydrogen react following addition reactions with
1.
2.
3.
4.
aldehydes
ketones
haloalkanes
both A and B
D
MCQ 52. Hydrogen Cyanide is
1.
2.
3.
4.
highly toxic
colorless
smell of almonds
all of them
D
MCQ 53. Ketones are formed by oxidation of
1.
2.
3.
4.
primary alcohols
secondary alcohol
tertiary alcohol
amines
B
MCQ 54. Carbonyl compounds have an odor similar to
1.
2.
3.
4.
almonds
grapes
fruits
blue cheese
A
MCQ 55. Carbonyl compounds when oxidized easily to form carboxylic group involves
1.
2.
3.
4.
aldehydes
ketones
haloalkanes
esters
A
MCQ 56. Solution which is used to detect presence of aldehyde or ketone is
1.
2.
3.
4.
2,4-dinitrophenylhydrazine
BNPH
both A and B
tollen's reagent
C
MCQ 57. Almond essence in cakes and pudding is made from
1.
2.
3.
4.
ester
alcohol
benzaldehyde
ketone
C
MCQ 58. In redox reaction, Ag+ ions are theirself
1.
2.
3.
4.
oxidized
reduced
stable
polarized
B
MCQ 59. Carbonyl compounds are
1.
2.
3.
4.
aldehydes
ketones
both A and B
alcohols
C
MCQ 60. Secondary alcohol forms ketone and water by reacting with
1.
2.
3.
4.
oxygen atom
oxygen molecule
ozone molecule
oxygen ion
A
MCQ 61. HCN undergoes Nucleophilic addition reaction to give product of
1.
2.
3.
4.
hydrogen cyanide
hydroxynitrile
hydroxyl amine
all of them
B
MCQ 62. Primary alcohol is gently heated to produce aldehyde in presence of solution of
acidified
1.
2.
3.
4.
hydroxide
dichromate
ethanol
all of them
B
MCQ 63. In order to identify precipitates which are obtained can be matched with respecting
1.
2.
3.
4.
melting point data
electronegativity
polarity
masses
A
MCQ 64. An aqueous solution of silver nitrate in excess ammonia called
1.
2.
3.
4.
ammoniacal silver nitrate solution
Tollen's reagent
Fehling's solution
both A and B
D
MCQ 65. Solution which contain copper(II) ions (Cu+2) is
1.
2.
3.
4.
alkaline
Fehling 'solution
acidic solution
both A and B
D
MCQ 66. Amines which are bonded in Alkyl group are
1.
2.
3.
4.
primary amines
secondary amines
tertiary amines
quaternary amines
A
MCQ 67. A link between amino acid molecules in a poly peptide chain by condensation reaction
is called
1.
2.
3.
4.
peptide bond
poly peptide linkage
diol linkage
amine linkage
A
MCQ 68. Amino acids which we obtain from food and our bodies are unable to build them are
1.
2.
3.
4.
twenty
forty
twelve
eight
D
MCQ 69. Trim ethylamine is an example of
1.
2.
3.
4.
primary amines
secondary amines
tertiary amines
quaternary amines
C
MCQ 70. A reaction in which organic molecules join together along with elimination of water
molecule or HCl is called
1.
2.
3.
4.
addition
substitution
condensation
evaporation
C
MCQ 71. Hydrolysis of substituted amides will give product of
1.
2.
3.
4.
carboxylic acids
amines
both A and B
alcohols
C
MCQ 72. Amines and its derivatives are used to treat diseases like
1.
2.
3.
4.
malaria
insomnia
sleeping sickness
all of them
D
MCQ 73. Structural formula -CONH2 is representing
1.
2.
3.
4.
alkyls
amines
amides
arenes
C
MCQ 74. Amides give products of sodium salt of caboxylic acid and primary amine in presence
on aqueous sodium hydroxide by reacting with
1.
2.
3.
4.
acids
bases
alkalis
metals
C
MCQ 75. Ion which carries two charges, positive and negative is called
1.
2.
3.
4.
azonium ion
zwitterions ion
uranium ion
plutonium ion
B
MCQ 76. Reaction in which diazonium ion reacts with an alkaline solution of phenol to produce
azo dye is called
1.
2.
3.
4.
coupling reaction
desorption
diazotization
assimilation
A
MCQ 77. Some primary amines do not have NH2 group at end and are indicated by
1.
2.
3.
4.
numbering
alphabets
roman letters
greek letters
A
MCQ 78. A very important group of compounds which contain amino group and carboxylic
group is called
1.
2.
3.
4.
amines
amides
amino acids
all of them
C
MCQ 79. Bromine water does not react with benzene at
1.
2.
3.
4.
high temperature
low temperature
room temperature
constant temperature
C
MCQ 80. Vanillin is used to give flavor in
1.
2.
3.
4.
ice-cream
chocolate
frozen yogurt
both A and B
C
MCQ 81. Phenol is
1.
2.
3.
4.
solid
crystalline solid
gas
liquid
B
MCQ 82. Reaction of Phenol with alkali results in a
1.
2.
3.
4.
salt
water
gas
both A and B
D
MCQ 83. Phenol undergoes ionization to become more stable by reacting with
1.
2.
3.
4.
negative ions
positive ions
both A and B
neutral atoms
A
MCQ 84. π-bonds in benzene spread over all six carbons, hence they are called
1.
2.
3.
4.
delocalized
spectators
inhebitors
invaders
A
MCQ 85. Phenol is stronger acid than water and itself it is
1.
2.
3.
4.
weakly acidic
weakly basic
alkali
strong acid
A
MCQ 86. Halogenoarenes are banned due to its
1.
2.
3.
4.
degradation
unreactiveness
non-toxicity
all of them
A
MCQ 87. Phenol dissolves well in
1.
2.
3.
4.
alkalis
acids
bases
water
A
MCQ 88. Organic compounds which contain one more than one benzene rings are termed as
1.
2.
3.
4.
arenes
aryls
acyls
benzenes
A
MCQ 89. Melting point of phenol is
1.
2.
3.
4.
55°C
43°C
25°C
15°C
B
MCQ 90. KOH is used in making of
1.
2.
3.
4.
drain cleaner
antacid
cement
liquid
D
MCQ 91. Acid used for manufacture of fertilizers and explosives is
1.
2.
3.
4.
Nitric acid
Sulfuric acid
phosphoric acid
hydrochloric acid
A
MCQ 92. PH at which methyl red changes color is
1.
2.
3.
4.
7
5.5
3.8
9
B
MCQ 93. Substances that react with both acids and bases are called
1.
2.
3.
4.
neutral
conjugate bases
amphoteric substances
conjugate acids
C
MCQ 94. Acids ionize in water to produce
1.
2.
3.
4.
OH- ions
H+ ions
SO4-2 ions
H2O molecules
B
MCQ 95. Corrosive effect on skin is caused by
1.
2.
3.
4.
acids
bases
water
mercury
A
MCQ 96. PH of water is
1.
2.
3.
4.
8
3
2
7
D
MCQ 97. In pure water, concentrations of
1.
2.
3.
4.
H+ and OH- ions are equal
H+ ions is more
OH- ions is more
Cl- is more
A
MCQ 98. Phenolphthalein in acidic solution is
1.
2.
3.
4.
colorless
pink colored
yellow colored
orange colored
A
MCQ 99. If pH value is greater than 7, then solution is
1.
2.
3.
4.
acidic
basic
neutral
salty
B
MCQ 100. When acid reacts with metal carbonate, products are
1.
2.
3.
4.
salt
water
carbon dioxide
all of above
D
MCQ 101. Bases leaves blue litmus
1.
2.
3.
4.
red
pint
black
unchanged
D
MCQ102. Sodium metal is soft due to
1.
2.
3.
4.
weak metallic bond
strong metallic bond
large size
small size
1
MCQ 103. Elements which have properties of metals and non-metals are
1.
2.
3.
4.
amorphous
crystalline
metalloids
none of above
3
MCQ 104. As size of atom increases down group, electro positivity
1.
2.
3.
4.
increases
decreases
remains same
none of above
1
MCQ 105. Bromine is a non-metal in
1.
2.
3.
4.
solid state
liquid state
gaseous state
plasma state
2
MCQ 106. As compare to beryllium, magnesium is
1.
2.
3.
4.
less electropositive
more electropositive
large in size
both B and C
4
MCQ 107. A mixture that consists of different components is called
1.
2.
3.
4.
homogeneous mixture
heterogeneous mixture
mixture
none of above
2
MCQ 108. Free radicals are electrically
1.
2.
3.
4.
positively charged
negatively charged
can be both A and B
neutral
4
MCQ 109. Empirical formula for water is
1.
2.
3.
4.
CO2
H
H2
H2O
4
MCQ 110. Hair contains keratin proteins which are also present in nails and wool is an example
of
1.
2.
3.
4.
Biochemistry
Inorganic chemistry
Physical chemistry
none of above
1
MCQ 111. Natural force that holds together elements together is called
1.
2.
3.
4.
chemical bond
force of attraction
gravitational force
physical bond
1
MCQ 112. Mass number of an atom is
1.
2.
3.
4.
no. of protons
no. of neutrons
A and B both
no. of electrons
3
MCQ 113. Smallest part of an element that cannot exist as a free state is
1.
2.
3.
4.
ion
charge
atom
molecule
3
MCQ 114. A free radical has
1.
2.
3.
4.
unpaired electrons
paired electrons
no electrons
even no. of electrons
1
MCQ 115. 1 mole of substance refers to
1.
2.
3.
4.
molar mass
atomic mass
electron mass
neutron mass
1
MCQ 116. Number of protons in nucleus constitute it's
1.
2.
3.
4.
atomic mass
atomic number
nucleon number
number of neutrons
2
MCQ 117. Vinegar contains
1.
2.
3.
4.
10% acetic acid
5%acetic acid
7% acetic acid
8% acetic acid
2
MCQ 118. 6.022 * 1023 atoms of Sulphur contains
1.
2.
3.
4.
2 moles
3 moles
4 moles
1 mole
4
MCQ 119. Negatively charged ions are called
1.
2.
3.
4.
cations
anions
ion
none of above
2
MCQ 120. Branch of chemistry which deals with substance containing carbon is called
1.
2.
3.
4.
carbon chemistry
inorganic chemistry
organic chemistry
environmental chemistry
3
MCQ 121. A free radical has
1.
2.
3.
4.
odd no. of electrons
even no. of electrons
A and B both
none of above
1
MCQ 122. Phenolphthalein in acidic solution is
1.
2.
3.
4.
colorless
pink colored
yellow colored
orange colored
1