Download Dermatological manifestations of HIV

DERMATOLOGICAL
MANIFESTATIONS OF HIV
Objectives:
*Pathogenesis of HIV infections:
**Types of virus and life cycle
**Briefly clinical manifestations of HIV infected
*Basis of drug used in treatment of HIV
*Dermatological manifestations of HIV
Briefly clinical manifestations of HIV
infected
Symptoms of HIV vary, depending on the individual
and what stage of disease you are in
The stages are:
1-early stage,
2- the clinical latency stage
3-or AIDS the late stage of HIV infection.
Early stage of HIV
Some people may experience a flu-like illness within
2-4 weeks after HIV infection.
But some people may not feel sick during this stage.
Flu like symptoms can include:
Fever and chills
rash
Night sweats
sore throat
Fatigue
swollen lymph nodes
Mouth ulcers
Clinical latency stage
HIV is still active but reproduces at low levels .
people with latent HIV infection may have any HIVrelated symptoms.
For people who are not taking medicine to treat HIV ,
this period can last a decade or longer, but some
may
progress through this phase faster


People who are taking medicine to treat HIV the
right way, every day may be in this stage for
several decades because treatment helps keep the
virus in check.
people can still transmit HIV to others during this
phase even if they are asymptomatic , although
people who are on ART and stay virally suppressed
(having a very low level of virus in their blood) are
much less likely to transmit HIV than those who are
not virally suppressed.
PROGRESSION TO AIDS
If HIV infection not treated the virus will weaken the
body’s immune system >>progress to AIDS (acquired
immunodeficiency syndrome) which is the late stage of
HIV infection.
Symptoms of AIDS
1-Rapid weight loss
2-Recurring fever or profuse night sweats
3-Extreme and unexplained tiredness
4-Prolonged swelling of the lymph glands in the
armpits, groin, or neck
5-Diarrhea that lasts for more than a week
6-Sores of the mouth, anus, or genitals
7-Pneumonia
8-Red, brown, pink, or purplish blotches on or
under the skin or inside the mouth, nose, or eyelids
8-Memory loss, depression, and other neurologic
disorders
Basis of drug used in treatment of HIV

HIV medicines are grouped into five drug classes
according to how they fight HIV:

1- non nucleoside reverse transcriptase
inhibitors(NNRTIs)
2- Nucleoside reverse transcriptase inhibitors (NRTIs)
3- Protease inhibitors (PIs)
DERMATOLOGIC
MANIFESTATIONS OF HIV
HIV-infected persons commonly
have cutaneous abnormalities
CLASSIFICATION OF CUTANEOUS
LESIONS IN HIV INFECTIOUS
Herpes zoster
Herpes simplex
Cryptococcus
Histoplasmosis
Human papillomavirus
Impetigo
Lymphogranuloma venereum
Molluscum contagiosum
Syphilis
Furunculosis
Atopic Dermatitis
Hair change
Folliculitis
Dermatmyositis
Kaposi’s sarcoma
Lymphoma
Squamous cell ca rcinoma
Pruritic papular eruption
Eosinophillic folliculitis
Seborrheic dermatitis
Drug eruption
Vasculitis
Psoriasis
Hyperpigmentation
Photodermatitis
seborrheic dermatitis
Kaposi sarcoma
Group B2 :
Nada alotaibi
Fatimah alkhalil
Sara aljamaan
Shehana alshammri
Asma asiri
Eman alhammad
Yaqout almutairi
Khulood alghamdi
Shaima aldosary
Ranin omar
Fatimah alali
Ghadeer bojoied