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EE 497 – RECENT TRENDS IN BIOMEDICAL ENGINEERING (Special Topics for Biomedical Engineers) Bulletin Description: Basics of Bioinformatics and its link to current problems in medical informatics including drug design, DNA based diagnostics, Biochips, Smart extracellular matrix and biomaterials, tissue engineering, Surface modification, Nanofabrication and biocompatibility issues, BioMEMS, Microfluidics, Nanorobotics Prerequisites: BIO 321 E Textbooks: Not Specific References: Handouts, Published Review Papers and Downloads from Internet Resources to be supplied by the Instructor Course Learning Objectives (CLO) After finishing the course successfully, the student shall 1. Understand and relate basics of genomics and proteomics in order to appreciate biomedical informatics 2. recognize biomolecule as tiny machine performing functions like motors and sensors 3. identify frontiers in biomedical engineering sciences and exploratory technology to find solutions to biomedical problems including issues like drug delivery, drug design, drug targeting, nanoimaging, high throughput screening and diagnosis. 4. describe the tissue engineering pursuits and will be able to relate as how regenerative medicine can fight disease and provide rehabilitation in a better way. 5. identify how micro and nanofabrication coupled with biomaterials can bring solution to biocompatibility issues at molecular level 6. identify as how microfluidics can bring revolution in health diagnostics and cellular research 7. explain how nanorobotics and molecular machine technology can be used to kill cancerous cells selectively, and also how they can target tissues and deliver drugs on demand Special Topics: 1. Genomics and proteomics- overview 2. Biomedical informatics and drug design 3. Microarray technology and Biochips: its role in diagnosis and personalized medicines 4. Scaffold design and fabrication for tissue engineering 5. Biocompatibility 6. BioMEMS and Biosensors 7. Nanorobotics and biomolecular machines 8. Microfluidics and Lab-on-a-chip 9. Quantum dots and nanoimaging Prepared by: Dr. Mohammad Asif Hussain, December, 2009