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Achieving and Maintaining a Healthy Body Weight Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings 13 NHANES Data National Health And Nutrition Examination Survey, 1999-2002 •Indicated an estimated 65% of US adults are either overweight or obese • This represents a prevalence that is 16% higher than estimates from NHANES, 1988-94 •16% of children 9-16 yoa (~9 million) are overweight • This is triple the amount from 1980 estimates www.cdc.gov/nchs/products/pubs/pubd/hestats/obese/obse99.htm www.cdc.gov/nchs/products/pubs/pubd/hestats/obese/obse99.htm www.cdc.gov/nchs/products/pubs/pubd/hestats/obese/obse99.htm Obesity: Cause for Concern •Overweight & obesity results from a complex interaction between genes and the environment characterized by long-term energy imbalance •Major public health challenge as a major contributor to preventive death in the US Copyright © 1998 NIH Publication No. 98-4083 Obesity Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 13.10 Disorders Related to Energy Intake Overweight and obesity – epidemic in US linked to many chronic diseases: Hypertension Dyslipidemia - elevated total cholesterol, triglycerides, and LDL cholesterol, and decreased HDL cholesterol Type 2 diabetes Heart disease and stroke Gallbladder disease Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Disorders Related to Energy Intake Overweight and Obesity – epidemic in US linked to many chronic diseases: Osteoarthritis Sleep apnea Certain cancers: colon, breast, endometrial, and gallbladder Gestational diabetes, premature fetal deaths, neural tube defects, and complications during labor and delivery Depression Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Why treat obesity? •Condition substantially raises risk of morbidity and mortality •Evidence from controlled trials indicates that weight loss reduces risk factors for disease •Estimated that at any given time 30-40% of population are trying to lose weight • An estimated $30-40 billion is spent on diet products and self-help books yearly Copyright © 1998 NIH Publication No. 98-4083 What is a Healthful Body Weight? A healthful weight Is appropriate for your age and physical development Is maintained without constant dieting Is based on family history of body shape and weight Promotes good eating habits and allows for regular physical activity Is acceptable to you Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings What is a Healthful Body Weight? Underweight: having too little body fat to maintain health (BMI < 18.5 kg/m^2) Overweight: having a moderate amount of excess body fat (BMI 25-29.9 kg/m^2) Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings What is a Healthful Body Weight? Obese: having an excess of body fat that adversely affects health (BMI 30-39.9 kg/m^2) Morbid obesity: body weight exceeding 100% of normal, creating a very high risk for serious health consequences (BMI > 40 kg/m^2) Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Evaluating Body Weight A person’s actual weight is not the only factor to consider Determining if a person’s body weight is healthful should include: Determining the Body Mass Index (BMI) Measuring body composition Assessing the pattern of fat distribution Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Evaluating Body Weight Body Mass Index Expresses the ratio of a person’s weight to the square of their height BMI = weight (kg) / height (m)2 BMI = [weight (lbs) / height (inches)2] X 703 BMI values below 18.5 or above 30 have increased health risks Correlates with both morbidity & mortality Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Evaluating Body Weight Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 13.1 Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 13.2 Evaluating Body Weight Body composition Measure of body fat and lean body mass Can be measured by Underwater weighing Skinfold measurements Bioelectric impedance analysis Near infrared reactance Dual-Energy X-Ray Absorptiometry Bod Pod™ Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Evaluating Body Weight Fat distribution pattern Apple-shaped fat patterning – upper body Increased risk for chronic diseases Men tend to store fat in their abdominal region Pear-shaped fat patterning – lower body No significant increased risk for chronic diseases Women tend to store fat in their lower body Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 13.3 Evaluating Body Weight Fat distribution pattern: Abdominal fat increases chronic disease risk Waist-to-hip ratio Men’s waist-to-hip ratio is higher than 0.90 Women’s is higher than 0.80 Waist circumference Men above 40 in. (or 102 cm.) Woman above 35 in. (or 88 cm.) Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 13.4 Evaluating Body Weight Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Table 13.3 Gaining or Losing Weight Whether a person gains or loses weight depends on Energy intake vs. energy expenditure Genetic factors Childhood weight Behavioral factors Social factors Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Energy Balance Energy balance Occurs when energy intake = energy expenditure Energy intake is kcal from food Energy expenditure is energy expended at rest and during physical activity Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 13.5 Energy Intake When total daily energy intake exceeds the amount of energy they expend, weight gain results An excess intake of approximately 3,500 kcal will result in a gain of one pound Without exercise, this gain will likely be fat Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Energy Expenditure Energy is expended to maintain basic body functions and to perform activities Total 24-hour energy expenditure is composed of three components: Basal metabolic rate (BMR) Thermic effect of food (TEF) Energy cost of physical activity Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 13.6 Energy Expenditure Direct calorimetry is a method that measures the amount of heat the body releases Indirect calorimetry estimates energy expenditure by measuring oxygen consumption and carbon dioxide production Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Energy Expenditure Basal Metabolic Rate (BMR) Energy expended to maintain basal, or resting, functions of the body The highest proportion of total energy expenditure (60-70%) BMR increases with more lean body mass, during stress, and periods of growth BMR decreases with age and during energy restriction Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 13.8 Energy Expenditure Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Table 13.4 Energy Expenditure Thermic Effect of Food (TEF) Energy expended to process food About 5-10% of the energy content of a meal Energy cost of physical activity 20-35% of someone’s total energy output each day About Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Genetic Factors About 25% of one’s body fat is accounted for by genetic influences Different ideas have been suggested to explain the impact of genetics on body fat Thrifty Gene Theory Set-point Theory Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Genetic Factors Thrifty gene theory Proposes that a gene (or genes) causes people to be energetically thrifty Proposes that people with this gene expend less energy than other people and therefore gain weight A “thrifty gene” has not been identified Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Genetic Factors Set-point theory Proposes that each person’s weight stays within a small range (set point) The body compensates for changes in energy balance and keeps a person’s weight at their set point Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Childhood Factors Environmental factors in childhood can influence Food choices Activity levels Later adult behaviors Childhood overweight increases the risk of heart disease and premature death as an adult Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 13.11 Composition of the Diet Theory states that overeating dietary fat promotes storage as adipose tissue Overeating carbohydrate or protein will also lead to weight gain Important to maintain a balanced diet combining fat, carbohydrate, and protein Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Physiologic Factors Hunger vs. appetite Proteins affect the regulation of hunger and storage of body fat Leptin acts to reduce food intake (feeling of satiety) Ghrelin stimulates food intake Peptide YY (PYY) decreases appetite Uncoupling proteins in brown adipose tissue increase energy expenditure Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Physiologic Factors Increase satiety (or decrease food intake) Hormones – serotonin, cholecystokinin (CCK) Increase in blood glucose levels after meal Stomach expansion Nutrient absorption from the small intestine Decrease satiety (or increase food intake) Hormones - beta-endorphins Neuropeptide Y Decreased blood glucose levels Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Social Factors Social factors influencing our diet include: Family or cultural traditions Holidays and celebrations Easy access to high-fat foods Less physically active lifestyles Societal expectations of the “perfect” body Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Achieve & Maintain Healthful Weight Healthful weight change requires Gradual change in energy intake Regular and appropriate physical exercise Application of behavior modification techniques Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Set appropriate and realistic goals •Initial goal of weight loss therapy is to reduce body weight by ~10% from baseline in 6 months of therapy •Depending on the amount of overweight/obesity a decrease of 500-1000 kcal/day will lead to weight losses of ~1-2 pounds/week Copyright © 1998 NIH Publication No 98-4083 Set appropriate and realistic goals •After 6 months, the rate of weight loss usually declines and weight plateaus (changing resting metabolic rates & difficulty adhering to lifestyle) •Experience reveals that lost weight usually will be regained unless a weight maintenance program consisting of diet therapy, physical activity, and behavior therapy is continued indefinitely Copyright © 1998 NIH Publication No. 98-4083 Weight Loss Diets High-fat, low-carbohydrate, high-protein diets Cause ketosis, which will decrease blood glucose and insulin levels and reduce appetite Dr. Atkins’ Diet Revolution, Protein Power Nutritionally inadequate, require supplements Side effects: constipation, diarrhea, nausea, headaches, ketone breath, insomnia, fatigue Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Weight Loss Diets Moderate-fat, high-carbohydrate, moderateprotein diets Balanced in nutrients: 20-30% calories from fat, 55-60% carbohydrate, 15-20% protein Weight Watchers, Jenny Craig, DASH diet, and the USDA MyPyramid Gradual weight loss (1-2 pounds per week) Typical energy deficits 500-1000 kcal per day Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Weight Loss Diets Low-fat and very-low-fat diets About 11-19% of total energy as fat, while very-low-fat-diets contain less than 10% Dr. Dean Ornish’s Program for Reversing Heart Disease and The New Pritikin Program Emphasize complex carbohydrates and fiber Regular physical activity is a key component Lower LDL cholesterol, triglyceride, glucose, insulin levels, and blood pressure Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Achieve & Maintain Healthful Weight Safe and effective weight loss Follow recommended serving sizes Reduce high-fat and high-energy food intake Regular physical exercise: increase energy expenditure and BMR Start slow & increase gradually Long-term goal: accumulate at least 30 minutes of moderate intensity activity on most, and preferably all, days of the week Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Achieve & Maintain Healthful Weight Weight loss medications: Many have been removed from market Should never be used without lifestyle modifications Herbal supplements: Not FDA regulated Recent “nationwide alert” of tainted weight loss supplements Can pose very serious health risks Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings What do “successful losers” have in common •The National Weight Control Registry •People volunteered to participate in study if they met criteria of maintenance of at least 30 lb weight loss for at least one year (4000 participants) •Commonly shared features: • • • • Ate a low-fat, high-carbohydrate diet Ate breakfast almost every day Frequent self-monitoring of weight Had high level of physical activity (~60-90 min mod-intensity activity every day) Bariatric Surgery •May be advisable in those with BMI > 40, or for those with BMI > 35 with other comorbidities, whose efforts at other therapies have failed • Vertical banded gastroplasty • Gastric bypass • Gastric banding •Compared to other interventions, surgery has produced the longest period of sustained weight loss Copyright © 1998 NIH Publication No. 98-4083 Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Figure 13.12 Achieve & Maintain Healthful Weight Effective weight gain: Eat 500 to 1,000 extra kcal/day Eat frequently throughout the day Maintain a balanced diet Eat a diet that contains 55% of total energy from carbohydrate; 25-35% of total energy from fat; and 1020% of total energy from protein Avoid tobacco (depress appetite and increase BMR) Exercise regularly with resistance training Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings