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Department of Biophysics All India Institute of Medical Sciences New Delhi DST - Fund for Improvement in S&T Infrastructure Brief Outline of the Department Department of Biophysics, All India Institute of Medical Sciences, New Delhi was established on February 28, 1962 to carry out research in front-line areas of medicine and modem biology and contribute in the teaching of various courses such as B.Sc. (Hons in Human Biology), M.Sc. (Biophysics), M.D.(Biophysics) and Ph.D.(Biophysics). It started with faculty strength of 4 and 2 senior scientists/Technical Officers. It has now grown into a full fledged department with 8 faculty members and 5 scientist positions. Teaching and Research Activities The department is involved in various teaching programmes such as B.Sc. (Hons) Human Biology, M.B.B.S., M.Sc., M.D. and Ph.D. So far, the department has produced approximately 100 Ph.Ds, 58 M.Ds, 48 M.Sc., and 45 B.Sc (Human Biology) degrees. The research programmes involve a wide range of projects in basic and applied disciplines of Biophysics. The current focus of the research is on structure determination of proteins and ligand design leading to structure-based drug discovery. The most recent programme initiated by the department is on clinical proteomics that aims at identification of accurate molecular markers for various pathological conditions and detailed characterization of various proteins present in human body fluids and sera as potential targets for drug design. The department has a strong programme in molecular modeling and medical bioinformatics. The proteomics facility is also being used to examine the variations in the concentrations of various biomolecules after applying the reflexology effects. Facilities created The department has created the following facilities under the FIST programme: 1. Real time kinetics: BlACore -2000 system for carrying out a real-time kinetics and for determining the binding constants of various ligands with protein targets. 2. Protein Purification System: AKTA Purifier-10 it is being used for high throughput purification work of proteins and peptides. For Further details, please contact: Prof. T.P. Singh Head Department of Biophysics All India Institute of Medical Sciences New Delhi-110029 Tel: 2658 8931, 2659 3201 Fax: 2658 8663, 2658 8641 Email: [email protected]