Download KEY--BIO 212 SI Kukday--Cell Specialization 3/8

Cell Specialization
Supplemental Instruction
Iowa State University
Leader:
Course:
Instructor:
Date:
Caleb I.
BIOL 212
Dr. Kukday
3/8/2017
1.) Vocabulary Review- Match the Terms & Definitions:
a. Cells that can differentiate into
i.
Differential Gene Expression
any body cell
_k__
b. Utilize morphogen, gap genes,
ii.
Transcription Factors __l__
and pair rule genes to
iii. Zygote ___d__
differentiate.
iv.
Stem Cells __a__
c. Stem cells that can differentiate
into almost any body cell
v.
Totipotent __q__
d. Fertilized egg
vi.
Pluripotent _c___
e. Stem cells that can form limited
vii.
Multipotent ___e_
cell types
viii. Unipotent __i__
f. Genes that subdivide the
ix. Cell Migration __g__
organism into broad regions
x. CAMs __o__
g. Movement of a cell
h. Toward the tail of the organism
xi. Anterior _n___
i. Stem cells that can form only
xii. Posterior __h__
one cell type
xiii. Dorsal ___m__
j. Includes morphogens and gap
xiv. Ventral __s__
genes, further divides the
xv. Morphogens __p__
embryo into sections
xvi. Bicoid Protein _r___
k. This happens when certain parts
xvii. Transcriptional Hierarchies
of a chromosome are used
within to differentiate cells
__t__
l. Proteins that initiate
xviii. Gap Genes _f___
transcription of specific genes
xix. Pair-Rule Genes __ j __
m. Toward the back/spine of the
xx. Segment-Identity Genes
organism
_b___
n. Toward the head of the
organism
o. Cell adhesion molecules
p. A substance that governs the
pattern of tissue development
q. Stem Cells that can form all
adult cell types
r. A morphogen responsible for
developing the anterior portion
of an organism
s. Toward the belly of the
organism
t. Expressing different genes at
specific times to foster
development
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu
2.) Label the horse with the dorsal/ventral, anterior/posterior, and left/right planes included:
3.) Can you identify the properties of stem cells? Can you identify what makes them
different from somatic cells? // Can you distinguish between the different types of stem
cells based on potency? ----i.
What makes stem cells different from somatic cells? Can one turn into the other?
Do they have different DNA?
ii.
iii.
iv.
What type of stem cells would be found in a blastocyst (The initial unorganized
ball of cells after fertilization)?
pluripotent
What type of stem cell is a hematopoietic(blood cell) stem cell?
multipotent
What type of stem cell is a skin stem cell?
unipotent
4.) Can you explain the mechanism underlying differential gene expression? ----- Explain
how cells can have the same DNA yet be completely different in form and function. What
enzymes allow this to occur during development?
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu
5.) Can you identify roles of gap, pair-rule, and segment-identity genes? Can you, given a
defect in the embryo, identify which genes are mutated? ----- Discuss the following
think/team/share from class. On the lower image, think about which part would utilize
morphogens, gap genes, pair-rule genes, or segment-identity genes:
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu
Dr. Kukday’s “Can You?” Questions:
1.) Can you identify processes that are important during mammalian development?
2.) Can you describe the role that morphogens play during development? What are these
molecules? How do they contribute to development?
3.) Can you identify roles of gap, pair-rule, and segment-identity genes? Can you, given a
defect in the embryo, identify which genes are mutated?
4.) Can you explain the mechanism underlying differential gene expression?
5.) Can you identify the properties of stem cells? Can you identify what makes them
different from somatic cells?
6.) Can you distinguish between the different types of stem cells based on potency?
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu