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Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and preB–cell differentiation by Isabel Ferreirós-Vidal, Thomas Carroll, Benjamin Taylor, Anna Terry, Ziwei Liang, Ludovica Bruno, Gopuraja Dharmalingam, Sanjay Khadayate, Bradley S. Cobb, Stephen T. Smale, Mikhail Spivakov, Prashant Srivastava, Enrico Petretto, Amanda G. Fisher, and Matthias Merkenschlager Blood Volume 121(10):1769-1782 March 7, 2013 ©2013 by American Society of Hematology Ikaros-responsive genes in pre-B cells. Isabel Ferreirós-Vidal et al. Blood 2013;121:1769-1782 ©2013 by American Society of Hematology Genome-wide mapping of Ikaros binding sites in pre-B cells. Isabel Ferreirós-Vidal et al. Blood 2013;121:1769-1782 ©2013 by American Society of Hematology Ikaros-induced gene expression changes relating to pre-BCR signaling. Isabel Ferreirós-Vidal et al. Blood 2013;121:1769-1782 ©2013 by American Society of Hematology Ikaros-induced gene expression changes relating to the cell cycle. Isabel Ferreirós-Vidal et al. Blood 2013;121:1769-1782 ©2013 by American Society of Hematology Ikaros-induced gene expression changes relating to V(D)J recombination. Isabel Ferreirós-Vidal et al. Blood 2013;121:1769-1782 ©2013 by American Society of Hematology Ikaros target genes are differentially expressed in the context of hematopoiesis, lymphocyte lineage choice, and B-cell differentiation. Isabel Ferreirós-Vidal et al. Blood 2013;121:1769-1782 ©2013 by American Society of Hematology Ikaros targets in pre-B cells and genes differentially expressed during lymphoid lineage specification and differentiation in vivo share biological pathways. Isabel Ferreirós-Vidal et al. Blood 2013;121:1769-1782 ©2013 by American Society of Hematology
