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AP Biology Your inner Fish Name ___________________________ Remember the winter assignment- The Immortal life of Hener KEY CONCEPTS The human body contains genes and structures that we inherited from distant animal ancestors. Evolution, including human evolution, is a story of losses and gains in both genes and anatomy. Research in various scientific disciplines — including paleontology, comparative anatomy, developmental biology, and genetics — provides evidence of our evolutionary history. Humans are related to all other life on the planet. The phylogenetic tree of life is a representation of the evolutionary relationships among all species, including humans. ***State the evidence that the brain of the fish is very similar in structure to the human Brain. If the video does not get there view: http://www.pbslearningmedia.org/resource/6b43382f-01a4-4559-a3cf948917499b79/our-fishy-brain-your-inner-fish/ EXPLORE MORE Shubin, N. Your Inner Fish: A Journey into the 3.5-Billion-Year History of the Human Body (Vintage Books. New York, New York, 2009). How To Read an Evolutionary Tree, Understanding Evolution, http://evolution.berkeley.edu/evolibrary/article/phylogenetics_02. Learn Genetics, http://learn.genetics.utah.edu/content/selection/. Genetic Origins, DNA Learning Center, http://www.geneticorigins.org/. Tiktaalik roseae website, http://tiktaalik.uchicago.edu/resources.html The Immortal Life of Henrietta Lacks THIS IS DUE JAN 4, 2016, EMAIL IT IF YOU PLAN TO RETURN TO SCHOOL AFTER THAT DATE. www.pbs.org/innerfish PURPOSE To explore the issue of ethics in medical research and, in particular, the issue of informed consent, in the context of Henrietta Lacks and the HeLa cells. Introduction In this lesson, you will investigate the story of Henrietta Lacks, an African American woman who died of cervical cancer in 1951. Doctors sent some of her cancer tissue to medical researchers who had been unsuccessful at growing cells in the laboratory environment, but that changed with the HeLa cell cultures Exploration Begin this lesson by reading The Immortal Life of Henrietta Lacks by Rebecca Skloot which is an interview with the author that summarizes the book and the story behind HeLa cells. Think about your answers to these questions as you read this interview. These questions can also be found on the HeLa student sheet: http://sciencenetlinks.com/student-teacher-sheets/hela/ What differentiates HeLa cells from other human cells? Henrietta’s doctor removed her cancer tissue during an autopsy and didn’t tell her family. Do you think he should have asked her family for permission and why? How would you define informed consent? If you go to the dermatologist and he or she removes a mole, what do you think is done with that tissue sample? What do you think about that? How would you define bioethics? How would you handle the information of a project to the original owner of tissue Full version on line THE IMMORTAL LIFE OF HENRIETTA LACKS http://rebeccaskloot.com/wp-content/uploads/2011/03/HenriettaLacks_RGG.pdf http://www.eaton.k12.oh.us/userfiles/257/Classes/5056/HELA%20Full%20Text.pdf http://academics.boisestate.edu/undergraduate/files/2011/03/Henrietta-Lacks-Excerpt.pdf You may read the short version, there are two articles I have found that give reasonable summaries. the book is by far the better reads, but you are busy. THE IMMORTAL LIFE OF HENRIETTA LACKS SUMMARY http://www.shmoop.com/the-immortal-life-of-henrietta-lacks/summary.html Cracking the Code of the Human Genome http://www.smithsonianmag.com/science-nature/henrietta-lacks-immortal-cells-6421299/?no-ist www.pbs.org/innerfish Key concept Definition & examples from text Mapping genes Cloning Raw material The Common Rule Biobanks Donor restrictions Inventive effort Genetic rights DNA testing Genetic disease www.pbs.org/innerfish
