Download MSZO312_F

Writing anything except Roll Number on question paper will be deemed as an act
of indulging in unfair means and action shall be taken as per rules.
Roll No._________________
M Sc (Zoology) Semester III
MSZO312 – VERTEBRATE IMMUNOLOGY AND ANIMAL CELL
CULTURE
MODEL PAPER
Time: 3 Hrs
MM: 80
Note:
1. All questions are compulsory in section A. The answers of these questions are
limited upto 30 words each. Each question carries 2 marks.
2. Attempt FIVE questions in all from Section B, selecting ONE question either A of
B from each question. Answer of each question shall be limited upto 250 words.
Each question carries 6 marks.
3. Attempt 3 questions in all from section C. Answer of each question shall be
limited upto 500 words. Each question carries 10 marks.
SECTION A
1. a Name the cells of immune system.
b Name the macrophages residing in the liver, lungs, gut, kidney and brain.
c Differentiate between antigen and superantigen
d Define epitope and haptens.
e Define titre.
f What is complement system. Give pathways of complement system.
g Define hypersensitivity and give it types.
h Name three autoimmune diseases and give their symtoms.
i Name the equipments needed for animal cell culture.
j Define primary cell culture and give its characteristics.
SECTION B
2. A Differentiate between humoral and cell mediated response.
OR
B Explain the clonal selection theory.
3.
A Explain generalized structure of immunoglobulin.
OR
B Differentiate between isotype, allotype and idoiotypic antigenic determinants.
4.
A Describe the different types of ELISA antigen antibody interaction.
OR
B Differentiate between class I and II MHC (Major Histocompatibility complex)
molecules.
5.
A Explain the difference between exogenous and endogenous pathway of antigen
processing.
PTO
B
6.
7.
8.
9.
10.
11.
OR
Explain the steps in production of monoclonal antibodies through hybridoma
technology.
.
A Describe the types of culture media used for animal cell culture.
OR
B Explain how cells are disintegrated and maintained for animal cell culture.
SECTION C
Describe the structure of spleen.
Describe the various classes and subclasses of immunoglobulin's and give their
functions.
Explain the classical pathway of complement system.
Explain the applications of monoclonal antibodies.
Describe the cryopreservation technique used for maintenance of cell lines.
PTO
Writing anything except Roll Number on question paper will be deemed as an act
of indulging in unfair means and action shall be taken as per rules.
Roll No._________________
M Sc (Zoology) Semester III
MSZO312 – VERTEBRATE IMMUNOLOGY AND ANIMAL CELL
CULTURE
MODEL PAPER
Time: 3 Hrs
MM: 80
Note:
1. All questions are compulsory in section A. The answers of these questions are
limited upto 30 words each. Each question carries 2 marks.
2. Attempt FIVE questions in all from Section B, selecting ONE question either A of
B from each question. Answer of each question shall be limited upto 250 words.
Each question carries 6 marks.
3. Attempt 3 questions in all from section C. Answer of each question shall be
limited upto 500 words. Each question carries 10 marks.
SECTION A
1. a Name the cells of immune system.
b Name the macrophages residing in the liver, lungs, gut, kidney and brain.
c Differentiate between antigen and superantigen
d Define epitope and haptens.
e Define titre.
f What is complement system. Give pathways of complement system.
g Define hypersensitivity and give it types.
h Name three autoimmune diseases and give their symtoms.
i Name the equipments needed for animal cell culture.
j Define primary cell culture and give its characteristics.
SECTION B
2. A Differentiate between humoral and cell mediated response.
OR
B Explain the clonal selection theory.
3.
A Explain generalized structure of immunoglobulin.
OR
B Differentiate between isotype, allotype and idoiotypic antigenic determinants.
4.
A Describe the different types of ELISA antigen antibody interaction.
OR
B Differentiate between class I and II MHC (Major Histocompatibility complex)
molecules.
5.
A Explain the difference between exogenous and endogenous pathway of antigen
processing.
PTO
B
6.
7.
8.
9.
10.
11.
OR
Explain the steps in production of monoclonal antibodies through hybridoma
technology.
.
A Describe the types of culture media used for animal cell culture.
OR
B Explain how cells are disintegrated and maintained for animal cell culture.
SECTION C
Describe the structure of spleen.
Describe the various classes and subclasses of immunoglobulin's and give their
functions.
Explain the classical pathway of complement system.
Explain the applications of monoclonal antibodies.
Describe the cryopreservation technique used for maintenance of cell lines.
PTO