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MODULE EQUIVALENCIES BIOCHEMISTRY AND MICROBIOLOGY MODULES Code Title Description First Year Modules SIFG014 Introduction to Food Science and Technology History of food science and technology; preservation food processing, additives, analysis, quality control; process engineering; applied engineering. Food enzymes and their applications; browning reactions; causes of food change. Second Year Modules SIBC021 Introduction to Water, etc. Some important properties of water; law of mass action; pH; acids and bases; titration curves; buffers, etc. SIBDA21 Biomolecules I Carbohydrates; lipids (biological Nucleotides and nucleic acids. SIBDB21 Biomolecules II Proteins : amino acids; primary, secondary and tertiary structure; protein functions. SIBDB21 Biomolecules Practicals Qualitative and quantitative analyses of carbohydrates; lipids; proteins and amino acids; nucleic acids; vitamins; hormones, etc. NEW MODULE SIBDA21 SIBDC21 SIMC021 SIMC01 SIM033 SIMJ024 Biomolecules I Biomolecules II Introduction to Microbiology If the student has done SIFM01 - Classification of Bacteria and viruses and SIMD02 Ultra-structure of prokaryotes and eukaryotes (repeater students only) If the student has never done SIMC01 Nutrition and environmental influences on microorganisms Microbial Genetics and membranes); OLD MODULE SIBA03 SIBDA4 SITHO1 Introduction to Biochemistry Biomolecules Application of the Principles of Enzymology to Biotechnology SIMD02 SITI02 Ultrastructure of prokaryotes and Eukaryotes Environmental Biotechnology SITE03 Applications of the Principles of SIML024 SIBC021 SIBKB32 SIMS033 SIMD022 SIMI032 SBTBO13 SIBFC24 SIMS033 SISE014 SIBFC24 SIBFC24 SBTCO24 SIBIB34 SITF034 SBTC024 SBFC024 SITE033 Ecology Advanced Microbial Metabolism Introduction to Water Metabolic Regulation Practicals Immunology and Serology Ultrastructure of rokariotic and eucariotic cells Microbial Ecology Metabolism Practicals Immunology and Serology Medicinal Plants Practical Metabolism Practicals Metabolism Practicals Mycology Recombinant DNA Practicals Appl. Of Principles of Industrial Microbiology to Biotechnology Mycology Metabolism Practicals Appl. Of Principles of Genetics to Biotechnology SIBFB3 SIBKB2 SIMC021 SINV032 Genetics to Biotechnology Metabolism II Metabolic Regulation Practicals Introduction to Micriobiology Animal and Plant Virology SISK032 SITD022 Serology Practicals Downstream processing SITGO32 SIBA013 SIBFC23 SISL033 SISD014 SIBFD24 SIBFD24 SISI024 SISM024 SIMHB24 Substrate forBiotechnology Introduction to Biochemistry SIMJ024 SIML024 SIMN024 Micriobial Genetics Advanced Microbial Metabolism Micriobial Genetics and Ecology Practicals Haematology Practicals Medicinal Plants Medical Biochemistry Control of Microbial Growth Microbial Growth Practicals MODULE DESCRIPTION BIOCHEMISTRY AND MICROBIOLOGY MODULES Code Title Description SIBEA22 Enzymology I Enzyme nomenclature; mechanisms of enzyme action. SIBEB23 Enzymology II Enzymatic catalysis; enzyme kinetics; inhibition and regulation; cofactors and coenzymes. Application of immobilisation to biotechnology. SIBEC24 Enzymology Practicals Protein structure; protein purification; enzyme assays; Substrate assays; protein ligand binding studies; Immobilised enzymes; amino acid composition and sequence. SIBFA22 Metabolism I Introduction to metabolism; biochemical energetics; Glycolysis; citric acid cycle; electron transport and oxidative phosphorylation; photosynthesis carbon-nitrogen- and sulphur cycles. SIBFB23 Metabolism II Lipid and protein metabolism; mammalian fuel metabolism; regulation of metabolism; nucleotide metabolism; integration of carbohydrate, lipid and protein metabolism. SIBFC24 Metabolism Practicals Metabolic experiments involving carbohydrates, lipids, amino acids, nucleotides and mammalian fuels. SIBQA23 Practical Biochemistry General principles; immuno-chemical; molecular biology; Principles and Techniques I proteins and enzymes; radioisotopes; Centrifugation. SIBQB24 Practical Biochemistry Principles and Techniques II Spectroscopic; mass spectrometric; electrophoretic; Chromatographic and electrochemical. SIFD024 Starvation/Malnutrition Malnutrition and under-nutrition; kwashiorkor and marasmus as nutritional diseases; obesity and metabolic adaptations due to malnutrition; acute and chronic starvation; metabolic enzymatic and hormonal adaptations during acute and chronic starvation. Acute and chronic starvation; metabolic-, enzymatic- and hormonal adaptations during acute and chronic starvation. SIFQA22 Quality Control I Regulatory agencies (RDA); evaluations; reporting results. SIMD022 Ultra Structure of Prokaryotic and Eukaryotic Cells Composition and structure of prokaryotic and eukaryotic cells. food quality; sensory BIOCHEMISTRY AND MICROBIOLOGY MODULES Code Title Description SIMF021 Classification of Bacteria and Fungi Types of bacteria and fungi; classification according to colony; cellular structure, staining abilities, etc. SIMG022 Microbial Techniques Culture media; isolation of microorganisms; maintaining viable cultures; sterilisation methods and disinfectants. SIMHA23 Microbial Growth Nutrition requirements of microorganisms; effect of carbon, nitrogen, phosphorous and iron cycles on microorganisms. Cellular growth; population growth; growth cycles; Continuous cultures; measurement of microbial growth. SISO021 HIV / AIDS AIDS; HIV I; HIV II; HIV infection; symptoms and progress of AIDS; Transmission and prevention of AIDS; possible origins of the disease; research toward prevention or cure Third Year Modules SIBGA31 SIBGB32 SIBIA33 Gene Expression and Replication I Gene Expression and Replication II Recombinant DNA SIBIB34 Recombinant DNA / Genetics Practicals SIBJA31 Biochemistry of Nutrition SIBJB32 Biochemistry of Nutrition Practicals Nucleic acid structures; DNA replication; DNA repair; DNA recombination. Transcription and RNA processing; translation; regulation of gene expression; protein biosynthesis. Cloning; DNA libraries; recombinant DNA technology; applications of recombinant DNA technology. Application of enzyme engineering to biotechnology. Structure, function and isolation of nucleic acids; physiological analysis of DNA; outline of genetic manipulation. Enzymes in genetic manipulations; cloning vectors; Isolation of nucleic acid sequences; expression of genes. Assay animals; human nutritional requirements; protein; lipid; carbohydrate; mineral nutrients; water-soluble and fat-soluble vitamins; ‘optimal diet’. Malnutrition; rehabilitation of malnutrition; analyses of metabolic active compounds from natural sources. BIOCHEMISTRY AND MICROBIOLOGY MODULES Code Title SIBKA31 Metabolic Regulation SIBKB32 Metabolic Regulation Practicals Biotechnology SIBLA33 Description Control of enzyme activities; control of specific metabolic pathways involving carbohydrates, proteins, lipids, nucleic acids, etc. Extrinsic and intrinsic regulation feedback inhibition. Study of glucose and lactate metabolism after fasting and exhaustive exercise. Definition of biotechnology and its contents Fermentation. Applications in Biotechnology. SIBLB34 SIF0032 SIFN033 SIFP033 SIFQB34 SIMI032 SIMM031 SIMO031 Biotechnology Practicals Fermentation biotechnology; application of enzymes; Food biotechnology. Food Technology Practicals Standard methods applicable to food technology; food energy determinations; proximate analysis of food. Microbial tests applicable to food technology. Food Definitions; nutrients; colorants; flavouring; antioxidants; Additives/Preservation acidulants; sweeteners; etc. Food Analysis Sampling; proximate analysis; current equipment in food analysis. Quality Control II Microbial Ecology Soil; water; air, and rumen microbiology; bioleaching; Food spoilage; food poisoning; hygienic standards; Methods applied in food examination; toxic substances in food; food infection; food intoxication. Water analyses for various microorganisms; water purification for household consumption; water treatment to prevent water borne microbial diseases. Environmental Biotechnology Introduction to Viruses General properties of viruses; virus host; quantification of viruses; positive-, negative- and double stranded RNA viruses; DNA viruses; herpes-, pox-, adeno-, retro-, HIV Iand HIV II- viruses. Epidemiology and Epidemiology and public health microbiology; air borne Pathogenesis of Infectious transmission of pathogens; tuberculosis; viral infections; Diseases sexually transmitted diseases; insect and tick transmitted diseases; food and water borne diseases. Safety in medical laboratories BIOCHEMISTRY AND MICROBIOLOGY MODULES Code Title Description SIMR032 Anti-microbial Chemotherapy Sterilisation; physical control of microorganisms. Properties of anti-microbial agents; mechanisms of action of anti-microbial agents; development and evaluation of anti-microbial agents. Antibiotics; synthesis of antibiotics from various sources; Mechanism of action of various classes of antibiotics; Antibiotic resistance. SIMS033 Immunology and Serology Innate and acquired immunity. Immunoglobins, primary and secondary antibody responses. Major histocompatability complex. Mechanism of action of B and T lymphocytes, monoclonal antibody production. Serologic tests for hepatitis, syphilis, Rheumatoid arthritis, autoimmune diseases, chlamidiae, African trypanosonasis, Amebiasis and Bilharsiasis. SIREZ33 Research Project I In service training in related food industry SIREZ34 Research Project II In service training in related food industry SISG033 Clinical and Diagnostic Microbiology Aseptic techniques; isolation and purification of micro-organisms; identification of pathogenic bacteria; Study growth of microorganisms in different culture media and under different environmental conditions. Microscopy and staining procedures; isolation of pathogenic microorganisms from sources; anti-microbial sensitivity. SISHA33 Clinical Biochemistry I Clinical testing; disturbances of water, sodium and potassium balance; acid-base balance; renal disease, calcium, phosphate and magnesium metabolism; proteins in plasma; plasma enzyme tests in diagnosis; liver disease; gastrointestinal tract disease; nutrition. SISHB34 Clinical Biochemistry II Disorders of carbohydrate-,plasma lipids and lipoproteins-,iron, porphyrin and purine metabolism; Thyroid function; adrenal cortex and medulla; hypothalamic and pituitary hormones; gonodal function, steroid contraceptives and pregnancy; paediatrics and geriatrics; molecular biology; central nervous system; therapeutic drug monitoring and chemical toxicology. SISJ034 Endocrinology/ Serology/Haematology Practicals Determination of polypeptide, amine- and steroid hormones. Bilharzia ab; amoebic ab; cardiolipin ab; chlaydia ab; eonococcal ab; hepatitis a,b,c; herpes ab; thyroid ab; etc. Determination of haemoglobin; fibrinogen; prothrombin; Blood groups; haemolysis; malaria; reticulocytes; Full blood count; viscosity; etc. SITF034 Applications of the Principles of Industrial Microbiology to Biotechnology Metabolism of primary and secondary metabolites; Regulation of metabolism of primary and secondary metabolites; application of primary and secondary metabolites in biotechnology. SITL033 Research Project in the Field of Biotechnology Research project of limited extent on a specific aspect of biotechnology.