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14 PART A The Digestive System and Body Metabolism PowerPoint® Lecture Slide Presentation by Jerry L. Cook, Sam Houston University ESSENTIALS OF HUMAN ANATOMY & PHYSIOLOGY EIGHTH EDITION ELAINE N. MARIEB Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings The Digestive System and Body Metabolism Functions of digestive system: Ingestion: Taking in food. Digestion: Breaking down food physically and chemically. Absorption: Absorption of nutrients into the blood. Defecation: Ridding the body of indigestible remains. Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Organs of the Digestive System Figure 14.1 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Organs of the Alimentary Canal -a.k.a. gastrointestinal (GI) tract Mouth Pharynx Esophagus Stomach Small intestine Large intestine Anus Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Mouth (Oral Cavity) Anatomy Lips (labia) – protect the anterior opening Cheeks – form the lateral walls Hard palate – forms the anterior roof Soft palate – forms the posterior roof Uvula – fleshy projection of the soft palate Figure 14.2a Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Mouth (Oral Cavity) Anatomy Vestibule – space between lips and teeth/gums. Oral cavity – area contained by the teeth. Tongue – muscle attached at hyoid and styloid processes of the skull. Tonsils - Palatine and lingual. Lingual Frenulum – fold of membrane that secures tongue to floor of mouth. Figure 14.2a Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Processes of the Mouth Mastication (chewing) of food Mixing masticated food with saliva Initiation of swallowing by the tongue Taste Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Pharynx Anatomy Nasopharynx (not part of the digestive system) Oropharynx Laryngopharynx Figure 14.2a Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Pharynx Function Passageway for air and food Two muscle layers alternately contract to propel food (peristalsis): Longitudinal inner layer Circular outer layer Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Esophagus Runs from pharynx to stomach Conducts food by peristalsis Passageway for food only Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 4 Tissue Layers of Alimentary Canal Organs 1. Mucosa – moist innermost layer. 2. Submucosa – lies beneath mucosa made of connective tissue with blood vessels, nerve endings and lymph tissue. 3. Muscularis externa –smooth muscle containing both circular (inner) and longitudinal (outer) layers. 4. Serosa - Outermost (visceral) layer that contains serous fluid-producing cells Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Layers of Alimentary Canal Organs Figure 14.3 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Stomach Anatomy Food enters at the cardioesophageal sphincter Regions of the stomach Cardiac region Fundus Body Pylorus Food empties into the small intestine at the pyloric sphincter Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Stomach Anatomy Rugae – internal stomach folds of the mucosa Lesser curvature: concave medial surface. Greater curvature: convex lateral surface. Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Stomach Anatomy Figure 14.4a Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Stomach Functions Food storage tank Food breakdown Chemical breakdown of protein begins Delivers chyme (processed food) to the small intestine Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Specialized Mucosa of the Stomach Made of simple columnar epithelium containing: Gastric pits – formed by folds in mucosa Gastric glands (secrete gastric juice) Chief cells – produce protein-digesting enzymes (pepsinogens) Parietal cells – produce HCl Endocrine cells – produce gastrin Mucosa secretes sticky mucus. Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Structure of the Stomach Mucosa Figure 14.4b–c Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Small Intestine Body’s major digestive organ extending from pyloric sphincter to the ileocecal valve. Site of nutrient absorption into the blood Suspended from the posterior abdominal wall by the mesentery (fan-shaped membrane) Average length: 2.5 – 7 meters Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 3 Subdivisions of the Small Intestine 1. Duodenum: “twelve finger-widths long” (smallest) a. Attached to the stomach b. Curves around the head of the pancreas 2. Jejunum: “empty” a. Attaches anteriorly to the duodenum 3. Ileum: “twisted intestine” (largest) a. Extends from jejunum to large intestine Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Chemical Digestion in the Duodenum Pancreatic enzymes enter duodenum through the pancreatic duct. Bile from the liver enters duodenum through bile duct. Pancreatic ducts and bile ducts join to form hepatopancreatic ampulla. Pancreatic enzymes and bile then travel through duodenal papilla together to enter duodenum. Small intestine cells also secrete some enzymes in duodenum. Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Chemical Digestion in the Small Intestine Figure 14.6 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Absorption of the Small Intestine Three structures that increase absorption: 1. Microvilli – extensions of the cell membrane (makes it seem “fuzzy”) 2. Villi: Fingerlike structures formed by the mucosa (more surface area) 3. Circular folds: (a.k.a. plicae circulares) deep folds of small intestine. Figure 14.7a Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Large Intestine Larger in diameter, but shorter than the small intestine Frames the internal abdomen Extends from ileocecal valve to anus Function: Absorption of water Eliminates indigestible food from the body as feces Does not participate in digestion of food Goblet cells produce mucus to act as a lubricant Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Large Intestine Figure 14.8 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Structures of the Large Intestine Cecum – saclike first part of the large intestine Appendix - lymphatic tissue hanging from cecum that sometimes becomes inflamed (appendicitis) Colon Ascending Transverse Descending Sigmoid Colon Rectum Anus – contains external anal sphincter which is kept closed except during defecation. Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Accessory Digestive Organs Salivary glands – empty saliva secretions into mouth to aid in food breakdown and taste. Parotid (anterior to ears) Submandibular Sublingual Teeth Two sets of teeth (“baby” teeth (20)and adult teeth (32 with wisdom)) Pancreas Secretes enzymes into duodenum through pancreatic duct Produces hormone insulin Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Accessory Digestive Organs Liver Largest gland in the body Contains 4 lobes Suspended by diaphragm and abdominal wall by falciform ligament. Produces bile through common hepatic duct; enters duodenum through bile duct. Bile: contains many substances that break down fats (yellowish-green in color). Gallbladder Located on inferior surface of liver Stores bile when digestion is not occurring Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Processes of the Digestive System 1. Ingestion – getting food into the mouth 2. Propulsion – moving foods from one region of the digestive system to another (peristalsis (a)/segmentation (b)). Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Processes of the Digestive System 3. Mechanical digestion Mixing of food in the mouth by the tongue Churning of food in the stomach Segmentation in the small intestine 4. Chemical Digestion: enzymes break down food molecules into their building blocks Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Processes of the Digestive System 5. Absorption: products of digestion are absorbed in the blood or lymph. 6. Defecation: elimination of indigestible substances as feces Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Processes of the Digestive System Figure 14.11 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Control of Digestive Activity Mostly controlled by the parasympathetic division Chemical and mechanical receptors in organ walls Production of hormones (p. 475) Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings