Download The application of Magnesium sulphate (Epsom salt)

RAJIVGANDHI UNIVERSITY OF HEALTH SCIENCES
BANGALORE, KARNATAKA
PERFORMA FOR REGISTRATION OF SUBJECT FOR
DISSERTATION
Mr. ALEX JOHN
M.Sc. NURSING 1ST YEAR
MEDICAL SURGICAL NURSING
YEAR 2010-2012
PADMASREE INSTITUTE OF NURSING
BANGALORE
0
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES
BANGALORE, KARNATAKA
PERFORMA FOR REGISTRATION OF SUBJECT FOR
DISSERTATION
1.
NAME OF THE CANDIDATE
AND ADDRESS
Mr. Alex John
1st year M.Sc (Nursing)
Padmashree Institute of Nursing
Bangalore.
2.
NAME OF THE INSTITUTION
Padmashree Institute of Nursing
Bangalore.
3.
COURSE OF THE STUDY
AND SUBJECT
1st year M.Sc (Nursing)
Medical Surgical Nursing.
4.
DATE OF ADMISSION TO
THE COURSE
2nd July 2010
The effectiveness of application of
combination of Magnesium Sulphate
5.
and Glycerine dressing on management
TITLE OF THE STUDY
of limb oedema among patients with
Thrombophlebitis.
1
6. BRIEF RESUME OF THE INTENDED WORK
6.1 INTRODUCTION:
Circulatory system is major system in human body; veins are blood vessels
that carry blood towards the heart. Millions of veins are present in human body, the
length of veins are 60,000 – 100,000cm. Most of the veins carry deoxygenated blood
from the tissues back to the heart; exceptions are the pulmonary and umbilical veins,
both of which carry oxygenated blood to the heart. Vein colour is determined in large
part by the colour of venous blood, which is usually dark red as a result of its low
oxygen content. Veins are classified in a number of ways, including Superficial versus
Deep, Pulmonary versus Systemic, and Large versus Small. 1
The common disease conditions affecting veins are Thrombophlebitis, Deep
vein thrombosis, varicose vein, venous stasis ulceration and chronic venous
insufficiency. Phlebology is the medical discipline that involves the diagnosis and
treatment of disorders of venous origin. The American Medical Association has added
Phlebology to their list of self-designated practice specialties. A medical specialist in
Phlebology is termed a phlebologist.
Phlebitis means inflammation of a vein. Thrombophlebitis is the term used
when a blood clot in the vein causes the inflammation. Thrombophlebitis usually
occurs in leg veins, but it may occur in arms. The thrombus in the vein causes pain
and irritation and may block the blood flow in the veins. Blood clots (thrombi) can
form which may break off and travel to the lungs. This is a potentially life threatening
condition called Pulmonary embolism.2
The Thrombophlebitis is caused by an injury to a vein (mainly due to vein
puncture). Blood clot may occur due to sitting for hours at a time, confined to bed for
prolonged time, use birth control pills, pregnancy or immediately after birth, varicose
vein and obese.
2
Superficial Thrombophlebitis is usually an easily diagnosed condition; it may
be an iatrogenic, resulting from intravenous catheter or infusion of solutions. Deep
vein thrombosis (DVT) is Thrombophlebitis of deep veins. It is a common disorder,
more so in women than in men. Deep vein thrombosis develops in approximately one
third of clients older 40 years who have had major surgery, orthopaedic surgery, or
myocardial infarction. In addition clients with cancer or family history of clotting
disorders are at risk.
Phlebitis, if mild, may or may not cause symptoms. Pain, tenderness, redness
(Erythema), and bulging of the vein are common symptoms of phlebitis. The redness
and tenderness may follow the course of the vein under the skin. Low grade fever may
accompany superficial and deep phlebitis. High fever or drainage of pus from the site
of Thrombophlebitis may suggest an infection of the Thrombophlebitis (referred to as
septic Thrombophlebitis). Palpable cords along the course of the vein may be a sign of
a superficial clot or superficial Thrombophlebitis. A deep venous thrombosis may
present as redness and swelling of the involved limb with pain and tenderness. In the
leg, this can cause difficulty in walking.
The treatment
of Thrombophlebitis consist of self-care steps that include
applying heat to the painful area, elevating the affected leg and using an over-thecounter
non
steroidal
anti-inflammatory
drug
(NSAID),
medications
like
anticoagulant, support stockings and bypass surgeries.
Some recent trends in hospital care include the application of magnesium
sulphate (Epsom salt) for reducing the oedema. Some hospitals are having the practice
of this application. Epsom salts have an ability of absorbing or removing the water
content through skin; hence reduce the oedema which is scientifically proved.
The application of Magnesium sulphate (Epsom salt) alone may cause skin
irritation so any of the skin softeners also should apply with this; preferably Glycerine
used. Glycerine is a thick liquid that has a variety of uses. It is capable of softening
skin and it will help to nourish the skin tissues.4
3
The combination of magnesium sulphate and glycerine application on a limb
oedema with help of roller bandage and followed by limb elevation may help in
reduction of swelling and nourishment of skin as evidenced by studies. The nursing
interventions should be meaningful and affordable by the client in terms of this aspect
this study is relevant to the profession.
6.2 NEED FOR THE STUDY
Superficial Thrombophlebitis which occurs in about 65% of all patients
receiving intravenous therapy, deep vein Thrombophlebitis occurs at least 5% of
surgical patients.5
In hospitalized individuals, the incidence of venous thrombosis varies
considerably, from 20% to 80%, and the incidence of Deep vein thrombosis is
estimated to be about 80 cases per 100,000 populations annually. Superficial
Thrombophlebitis is very common in hospitalized patients, but frequency is not
known precisely because many cases go unreported and untreated. Deep vein
thrombosis frequency also is not known precisely because of misdiagnoses.6
In the year 2004, the annual hospital report of Kerala, stated that the incidence
of Thrombophlebitis was (78%) in ICU as compared to (30%) in general wards. The
study highlighted the cause as lack of physicians, nurses and poor standard of care
provided by health care personnel.7
A study was carried out on the clinical importance, diagnosis, incidence, and
pathogenesis of peripheral vein infusion Thrombophlebitis, including catheter-related
and patient-related risk factors. The study reviewed the evidence linking thrombosis,
particularly prothrombotic states such as the inherited thrombophilic disorders, with
peripheral vein infusion Thrombophlebitis. Peripheral vein infusion Thrombophlebitis
occurs in 25% to 35% of hospitalized patients with peripheral intravenous catheters
4
and has both patient-related implications (e.g., sepsis) and economic consequences
(e.g., extra nursing time). Although duration of catheterization, catheter-related
infection, and catheter material are important risk factors for peripheral vein infusion
Thrombophlebitis, patient-related risk factors are not well elucidated.8
If Thrombophlebitis is in a vein just under your skin (superficial vein),
complications are rare. However, if the clot occurs in a deep vein you may develop a
serious medical condition known as deep vein thrombosis. If that happens, the risk of
serious complications is greater. Complications may include: pulmonary embolism
and heart attack or shock.
A
study
was
conducted
on
the
importance
in
prevention
of
Thrombophlebitis, such as care against traumatisation of vessels, prevention of
infection, control of epidermophytosis, free movement in bed, early ambulation, deep
respiratory exercises and the avoidance of the latter in Thrombophlebitis to prevent
pulmonary embolism. Attention was called to the highly controversial nature of the
measures used in the treatment of Thrombophlebitis; some measure are, the
application of heat and cold, the use of leeches, prolonged rest, free exercise, early
ambulation, dependent and elevated position of the extremity, lumbosacral
sympathetic block, prophylactic venous ligation and the use of anticoagulant agents
are proved effective in reducing oedema.
The prevention of Thrombophlebitis is very much important in hospital set up.
The nurses have more responsibility to prevent the occurrence and complication
related to Thrombophlebitis. Special attention should be carried out for this purpose.
The limb oedema may cause immobility, tenderness, infection, fear and anxiety
related to disease condition, so reducing the oedema also important part of
nursing
care.
Magnesium sulphate (Epsom salt) is easily available in as a pharmaceutical
form. It is cheapest and more effective in reducing oedema. The cost effective care
5
also one of the main concepts of quality of nursing care. The cost effective
management is necessarily carried out to reduce oedema and anxiety related to care.
In a randomized double blind study on patients with oedema treated with one
of the following, magnesium sulphate (Epsom salt) and hot application. The result
revealed that there is more effectiveness of magnesium sulphate, in reducing oedema
than hot application.9
Thrombophlebitis may lead to dry, scaly and disntegrity of the skin. In order to
prevent complications of skin nurses should aware about the managements like
medications, moisturizing creams and application of glycerine
From the above information researcher has realized that there is high
prevalence of Thrombophlebitis among the patients with intravenous therapy. There
is a management for the limb oedema with the combination of the magnesium
sulphate and glycerine. The method is also very feasible and less expensive. These
factors made researcher to design a study to assess the effectiveness of application of
combination of magnesium sulphate and glycerine dressing on management of limb
oedema.
6.3 STATEMENT OF THE PROBLEM
A study to assess the effectiveness of application of combination of magnesium
sulphate and glycerine dressing on management of limb oedema among patients
with Thrombophlebitis in a selected hospital, Bangalore.
6
6.4 OBJECTIVES
1. To assess the level of limb oedema among patients with Thrombophlebitis
before the intervention.
2. To assess the level of limb oedema among patients with Thrombophlebitis after
the intervention.
3. To compare the pre test and post test level of limb oedema among patients with
Thrombophlebitis.
4. To associate the pre-test level of limb oedema among patients with
Thrombophlebitis with their selected demographic variables.
6.5 OPERATIONAL DEFINITIONS
1. Effectiveness:
The degree to which level of limb edema is reduced after the application of
dressing.
2. Magnesium sulphate and glycerine dressing:
It refers to the application of roller bandage coated with 20 grams of
magnesium sulphate diluted in 100 ml of glycerine that is applied on the limb
oedema. Magnesium sulphate is crystal like substance which helps to reduce
the oedema and glycerine is a thick liquid which help to moisturize and nourish
the skin.
3. Limb oedema:
Swelling present in either upper or lower extremities.
4. Thrombophlebitis:
Inflammation of vein followed by formation of clot after application of
intravenous infusion.
7
6.6 ASSUMPTIONS
1. Limb oedema may vary among patients with Thrombophlebitis.
2. Combination of magnesium sulphate & glycerine application may reduce
degree of limb oedema.
6.7 RESEARCH HYPOTHESIS
H1 – There will be a significant difference in the mean pre test and post test level
of limb oedema.
H2 – There will be significant association between the pre test levels of limb
oedema among the patients with Thrombophlebitis with their selected
demographic variables.
6.8 REVEIW OF LITERATURE
A literature review is summary of previous research on a topic which can be
either a part of a large report of a research project, a thesis or bibliographic essay that
is published separately in scholarly journal. The purpose of literature review is to
convey the reader what knowledge and ideas have been established on topic and what
are the strength and weaknesses. It allows the reader to bring up to date reading the
state of research in the field and familiarizes the reader with any contrasting
perspectives and view point on the topic. There are many reasons for beginning a
literature review before starting a research paper.
A comparative study was carried out on the incidence of Thrombophlebitis
following the use of two types of cannulae. There was a significantly lower incidence
of Thrombophlebitis in the Biovalve group (17%) compared to the Vialon group
(60%) at the end of seven days (p < 0.001). 10
8
A prospective study was carried out on the frequency of Thrombophlebitis and
bacterial contamination of cannulas associated with four commonly used intravenous
cannulas of differing length and chemical composition. For all cannulas the frequency
of Thrombophlebitis increased significantly with time. It was suggested that infusion
Thrombophlebitis could be eliminated as a clinical problem by the use of intermittent
short duration intravenous infusions.11
The occurrence of Thrombophlebitis in a coronary care unit was studied in
relation to the use of short plastic intravenous cannulae. The incidence of
Thrombophlebitis was 51% in cases where cannulae were used for continuous
infusion of glucose (5%) and (13%) for cannulae which were locked after the injection
of heparin. Only one case of infectious Thrombophlebitis was seen. The other cases of
Thrombophlebitis had a chemical or mechanical aetiology. Replacement of glucose
(5%) by a Nacl (0·9%) solution for continuous infusion reduced the incidence of
Thrombophlebitis to (33%).12
A randomized trial of two catheter materials, with consideration of 21 potential
risk factors, to identify risk factors for infusion related phlebitis with peripheral
intravenous catheters. The use of peripheral intravenous catheters made of peu-vialon
appears to pose the same risk for catheter-related infection as the use of catheters
made of Fep-Teflon, and Peu-vialon can permit longer cannulation with less risk for
phlebitis. 13
A prospective double-blind randomized study was conducted in 40 patients
with infusion-related Thrombophlebitis. The study concluded that transdermal
glycerine was useful therapy for infusion-related Thrombophlebitis showing evidence
of anti-inflammatory and analgesic effect. 14
A randomized double-blind study, 197 patients with atopic dermatitis were
treated with one of the following: a new moisturizing cream with (20%) glycerine, its
cream base without glycerine as placebo or a cream with (4%) urea and (4%) sodium
9
chloride.. In conclusion, a glycerine containing cream appears to be a suitable
alternative to urea/sodium chloride in the treatment of atopic dry skin.15
A questionnaire study was set up to assess the perceptions of risk factors for
infusion phlebitis among Swedish nurses, as their concepts of these factors may
influence the incidence. A majority of the nurses believed that insertion of a peripheral
venous catheter in the forearm and catheter rotation within 48 hours was protective.
These measures were not supported in recent studies and guidelines. Surveillance of
the educational level of staff, who inserts peripheral venous catheters, was an
important tool for reducing the incidence of infusion phlebitis.16
A study was carried out to determine the incidence of deep vein thrombosis
(DVT) in patients diagnosed with superficial Thrombophlebitis (STP) after presenting
to an outpatient DVT service. A total of 79 patients were diagnosed with STP after the
exclusion of DVT with the diagnostic protocol. The incidence of a subsequent
diagnosis of DVT on 6-month follow-up was three out of 79 patients (4%, 95% and
0.8% to 11%). 17
A community-wide study was conducted in 16 short-stay hospitals in
Metropolitan Worcester, to examine the incidence and case-fatality rates of deep vein
thrombosis and pulmonary embolism in patients hospitalized between July 1, 2003,
and December 31, 2004. Extrapolation of the data from that population-based study
suggested that there were approximately 170,000 new cases of clinically recognized
venous Thromboembolism in patients treated in short-stay hospitals in the United
States each year.18
A prospective cohort study was conducted to determine the incidence, clinical
presentation, and risk factors of deep venous thrombosis (DVT) in a high-risk group
of ICU patients receiving DVT prophylaxis. In that study, the incidence of DVT in a
group of high-risk ICU patients receiving DVT prophylaxis was (12%). Since scans in
patients without signs or symptoms suggestive of DVT were abnormal in only (3.6%)
10
of patients, venous scans should be performed only in patients with features
suggestive of DVT or pulmonary embolism.19
7. MATERIALS AND METHODS OF STUDY:
7.1 SOURCE OF DATA:
The data will be collected from patients with Thrombophlebitis admitted in a
selected hospital, Bangalore.
7.2 METHOD OF DATA COLLECTION:
i)
Research design
Pre Experimental one group pre test- post test design.20
ii)
Research variables
Independent variables:
Combination of magnesium sulphate and glycerine dressing.
Dependent variables:
The level of limb oedema among patients with Thrombophlebitis.
Demographic variables:
Age, sex, education, family income, duration of hospitalisation, occupation, diet
and diagnosis of patients with Thrombophlebitis.
iii)
Settings
The study will be conducted in K.C.G. Hospital, Bangalore.
iv)
Population
The population of the study will be all the patient with Thrombophlebitis in
K.C.G. hospital, Bangalore.
11
v)
Sample
The sample consists of the patients who fulfil the inclusion criteria and the sample
size is 60.
vi)
Criteria for sample selection
Inclusion criteria:
-
The patients with Thrombophlebitis.
-
Patients with pitting oedema.
-
Both male and female patients above 18 years of age.
Exclusion criteria:
-
The patient who are not willing to participate the study.
-
The patients who are having limb fracture.
vii)
Sampling technique
Non probability convenience sampling technique.
viii)
Tool for data collection
A structured questionnaire and pitting oedema scale are used as tool.
SECTION-A:
Questions related to demographic variables consisting of age, sex, education,
family income, occupation, diet, duration of hospitalisation and diagnosis.
SECTION- B:
Pitting oedema scale to assess the level of limb oedema.
ix)
Procedure for data collection
After obtaining permission from the concerned authority and informed consent
from the samples, the investigator will collect the data pertaining to demographic
variables.
12
The study will be conducted in the following phases,
PHASE 1: Pre test level of limb oedema will be assessed using pitting oedema
scale.
PHASE 2: 20gram of magnesium sulphate diluted in 100 ml of glycerine and this
combination applied on limb oedema with help of roller bandage and the limb will
be elevated. This procedure will be repeated two times in a day. The first dressing
will be applied for four hours followed by second application for the next four
hours.
PHASE 3: After second application of intervention the post test level of limb
oedema will be assessed by using the pitting oedema scale.
x)
Plan for data analysis
The data collected will be analyzed by using descriptive and inferential statistics.
Descriptive statistics: Frequency and percentage distribution will be used to
describe demographic variables.
Mean and standard deviation will be used to analyse the pre test and post test level
of limb oedema among the patient with Thrombophlebitis.
Inferential statistics: Wilcoxen’s test will be used to compare the pre test and
post test level of limb oedema among patient with Thrombophlebitis,
Chi-square test will be used to associate the pre test level of limb oedema among
patients with Thrombophlebitis with their selected demographic variables.21
xi)
Projected out comes
After application of combination of magnesium sulphate and glycerine dressing
on oedema of the limb there will be gradual reduction of limb oedema. This will
help to reduce complications of Thrombophlebitis.
7.3 Does the study require any investigations or interventions or other
human or Animals?
Yes, the application of a combination of magnesium sulphate and glycerine
dressing will be administered as an intervention for management of limb oedema.
13
7.4 Has ethical clearance been obtained from your institution?
Yes, permission will be obtained from the concerned authorities of the institution
and formal consent will be taken from the samples. Confidentiality and privacy of
data will be maintained
14
8. LIST OF REFERENCES
1. Tortora, Derricson. Principle of Anatomy and Physiology. 11th edition.USA:
Wiley Publications; 2007.
2. Suzanne C, Smeltzer. The text book of Medical surgical Nursing. 10th edition.
Philadelphia: LWW Publications;1996.
3. Joyce M Black, Jane Hawkis. Medical surgical Nursing. 8th edition. India:
Elsevier Publications; 2009.
4. Julith C. Evan. How Epsom Salts helps to reduce swelling. Alternative health.
Available from http://www.care2.com/greenliving/use-epsom-salts13wonderful
way.html.
5. Sharon Mantik Lewis, Margaret Mclean, Shannon Ruff Dirkson. Medical
Surgical Nursing. 6th edition. Missouri: Mosby publications; 2004.
6. Thrombophlebitis. Medical disability advisor. http://www.mdguidelines.com/
Thrombophlebitis.
7. Balachandran A. Hospital care. Arogya Mazika. Volume 3. Kollam: Manorama
publications; 2000.
8. Uslusoy E, Metes. Predisposing factors to phlebitis in patients with peripheral
intravenous
catheters.
Health
science
institute.
Available
on:www.ncbi.nlm.gov/pubmed145255568.
9. Juhvan, Charlie N. The treatment of swelling. Available from http://www.
annual.com/treatment/-swelling/epsomsalts/ 3434.
10. Gupta a, Mehta y, Juneja R, Trehan N. The effect of cannulae material on the
incidence
of
peripheral
venous
Thrombophlebitis.
Avail
from:
http://www.ncbi.nlm.nih.gov/pubmed/17924895.
11. Jack collin, F. L. Constable, Christine Collin and I. D. A. Johnston.
Thrombophlebitis and infection with various cannulas. Royal victoria infirmary.
Newcastle
upon
tyne.
United
http://www.ncbi.nlm.nih.gov/pubmed/17924895
15
kingdom.
Available
on
12. P. J. Van Den Broek, M. M. De herder-Swinkels, B. G. Moffie, H. C. Van den
Berg, J. Hermans. Thrombophlebitis. Anz journal of surgry 2003oct;73(10):7946. Available
from: http://pmj.bmj.com/content/69/807/37 abstract
13. Lodén m, Andersson ac, Anderson 13. Dennis G. Maki, Marilyn Ringer. Risk
factors for infusion related phlebitis with small venous peripheral catheters. Avail
on: www.annals.com
14. J.R. Berrazueta, J.J. Poveda. The anti- inflammatory and analgesic action of
topical glycerine in the treatment of infusion related Thrombophlebitis. Anz
journal of surgery 2003 oct;73(10):794-6.
15. Anderson C, Bergbrant im, Frödin T. The cochrane central register of controlled
trials.
The
cochrane
collaboration.
Available
on
http://onlinelibrary.wily.com/o/clcentral/article/042/ cn-00408640/frame. html
16. P. Paulseno. Perception of risk factors for infusion phlebitis among swedish
nurses. Journal american acad nurse practice. 2008 april 20;4:172-80.
17. Dewar C, Panpher S. Incidence of deep vein thrombosis in patients diagnosed
with superficial thrombophlebitis after presenting to an emergency department
outpatient deep vein thrombosis service.
Emerg Med Journal.
2010
Oct;27(10):758-61.
18. Anderson FA Jr, Wheeler HB, Goldberg RJ. A population-based perspective of
the hospital incidence and case-fatality rates of deep vein thrombosis and
pulmonary embolism. Arch Intern Med. 1991 May;151(5):933-8. Available on
www.Pubmed.com
19. Manik PE, Andrews L, Malini B. The incidence of deep venous thrombosis in
ICU
patients.
Vascular
journal
1997
march
3.
Available
on:
www.ncbi.nlm.gov/pubmed145
20. Polit F, Beck T. Nursing research –generating and assessing evidence for nursing
practice.8th edition: Wolters kluwer;2008.
21. Barbara H. Statiscal methods for health care research – inferential statistics. 3rd
edition: lippincot; 1997.
16
09. Signature of the candidates
:
10. Remarks of the guide
:
11.1 Name and designation of the guide
: Mrs. PRASANNA.K
HOD & Associate Professor
11.2 Signature of the guide
:
11.3 Co-guide (if any)
: Mr. VENKATESAN.B
11.4 Signature of co-guide
:
11.5 Head of the department
: Mrs. PRASANNA.K
11.6 Signature
:
12.1 Remarks of the principal
:
12.2 Signature of the principal
:
17