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November 2016 University of South Florida Morsani College of Medicine John F. Toney, MD, FACP, FIDSA MAILING ADDRESS: Infectious Diseases Section (111J) James A. Haley Veterans Hospital 13000 Bruce B. Downs Blvd. Tampa, Florida 33612 COMMUNICATION: Office: (813) 972-2000 ext. 6184 Fax: (813) 910-4049 (secure) E-mail: [email protected] or [email protected] EDUCATION: Medical School: Marshall University, Huntington, West Virginia, M.D. 1981. Undergraduate: Marshall University, Huntington, West Virginia, B.S. (magna cum laude) 1976. POSTGRADUATE TRAINING: Fellow, Division of Infectious Diseases and Tropical Medicine, University of South Florida College of Medicine, Tampa, Florida, 1984-1986. Resident, Department of Internal Medicine, University of South Florida College of Medicine, Tampa, Florida, 1981-1984. ACADEMIC APPOINTMENTS: Professor of Medicine, Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, University of South Florida, Tampa, Florida, 2006–present. Associate Professor of Medicine, Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, University of South Florida, Tampa, Florida, 2001–2006. Assistant Professor of Medicine, Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, University of South Florida, Tampa, Florida, 1986-2001. ACADEMIC/HOSPITAL POSITIONS: Director, Antibiotic Stewardship Program, James A. Haley Veterans Hospital, Tampa, Florida, 2010 present. Medical Director, Florida Infectious Disease Institute (FIDI), University of South Florida College of Medicine, Tampa, Florida, 2003 – 2012. Director, START Program (Sexually Transmitted Awareness, Research, and Training) University of South Florida College of Medicine, Tampa, Florida, 1999-2012. Medical Director, Southeast Region (formerly “Florida”) Sexually Transmitted Diseases – Human Immunodeficiency Virus Prevention Training Center (STD/HIV PTC), CDC National Network of STD/HIV Prevention Training Centers, 1988-2011. Faculty, University of South Florida Center for HIV Education and Research, University of South Florida College of Medicine, Tampa, Florida, 1991-2012. Director of Healthcare Epidemiology, James A. Haley VA Hospital, Tampa, Florida, 1991-present. Director of Clinical Research, Infectious Diseases Section, Medical Service, James A. Haley VA Hospital, Tampa, Florida, 1991-present. Acting Chief, Infectious and Tropical Diseases Section, Medical Service, James A. Haley VA Hospital, Tampa, Florida, 1991-1999. John F. Toney, MD Page 2 Director, Protective Care Unit, James A. Haley Veterans’ Hospital, Tampa, Florida, 1995-1999. Director of Clinical Research, Division of Infectious and Tropical Diseases, Department of Internal Medicine, College of Medicine, University of South Florida, Tampa, Florida, 1991-1995. HONORS AND AWARDS: Board of Directors, Tampa VA Research and Education Foundation. 2011-present Best Doctors in America. 2011-2016 Treasurer, University of South Florida College of Medicine Faculty Council. 2006–2008 and 2008-2010. President, Florida Infectious Diseases Society. 2001 – 2003. Secretary/Treasurer, Florida Infectious Diseases Society. 1999 – 2001. Vice-President, Florida Infectious Diseases Society. 1997 – 1999 Invited Testimonial, Labor, Health and Human Services, Appropriations Subcommittee, Washington, DC. 1996. Outstanding Poster Presentation Award (“Sexually Transmitted Diseases Attitudes and Knowledge in Trainees at a University Medical School”), Florida Chapter, American College of Physicians. 1994. PROFESSIONAL DEVELOPMENT: Supervisory Performance Management, U.S. Department of Veterans Affairs, July 17, 2012 Write Winning Grants, USF Health Clinical and Translational Sciences Institute (CTSI), May 11, 2011 Ethical Leadership Training, U.S. Department of Veterans Affairs, April 8, 2011 FOCUS: Achieving Your Highest Priorities, FranklinCovey, January14, 2011 Introduction to Creating Labor Management Forums to Improve Labor Relations and Productivity at VA, U.S. Department of Veterans Affairs, August 2, 2010 TEACHING ACTIVITIES: University Teaching Med Sciences (Med 2) Course 7 – Clinical Cases Sexually Transmitted Infections faculty, 2012-current BMS 5015 Clinical Diagnosis & Reasoning Course (CDR) faculty, 2007 - 2010. BMS 6920 Colloquium II faculty 2006-2009. BMS 6300 Principles of Medical Immunology and Infectious Diseases (PMIID) faculty, 2006 – 2012. BCC 6110 Internal Medicine Clerkship, 1986 - 2001. BMS 6810 Introduction to Clinical Medicine (lectures), 1986 - 2000. Hospital Teaching MEL 8334 General Internal Medicine Clerkship, Honors Program, 1991 - 2000. MEL 8338 Honors Acting Internship Program in Internal Medicine, 1993 - 2000. MEL 8371 Selected Topics in Infectious Diseases, 1995 - 2000. MEL 7117 Clinical Microbiology and Infectious Disease (lectures), 1995. MEL 9999 Independent Study in Infectious Diseases, 1993. MEL 7310 Infectious and Tropical Diseases, 1986 - present. MEL 8361 Clinical Sexually Transmitted Diseases (STDs), Course Director 1990 - 2012. MEL 8365 Outpatient Care of the HIV Patient, Attending, 1995 - 2010. John F. Toney, MD Page 3 INVITED LECTURES: National: Faculty, “STD 101” Pre-conference workshop, 2010 National STD Prevention Conference, Atlanta, Georgia, 2010. Faculty, “STD 101” Pre-conference workshop, 2008 National STD Prevention Conference, Chicago, Illinois, 2008. Faculty, “STD 101” Pre-conference workshop, 2006 National STD Prevention Conference, Jacksonville, Florida, 2006 Faculty, Conference Workshop, “VA Treatment and Management of HIV Infection in the United States” VHA National Conference, Atlanta, Ga. 2005. Faculty, “STD 101” Pre-conference workshop, 2004 National STD Prevention Conference, Philadelphia, Pennsylvania, 2004. Faculty, “STD 101” Pre-conference workshop, 2002 National STD Prevention Conference, San Diego, California, 2002. Regional: Invited Lecturer, “STD Trends amd Management Issues,” Florida Public Health Association (FPHA) Regional Meeting, Tampa, Florida, 2008. Faculty, Pre-Conference Workshop, 16th National HIV/AIDS Update Conference, Miami, Florida, 2004. Invited Lecturer, “Update on STDs” 29th Scientific Meeting, Florida Chapter, American College of Physicians, Longboat Key, Florida, 1997. Invited Lecturer, “STDs and Women’s Health” Florida Breast and Cervical Cancer Coalition Meeting, State of Florida Tampa, Florida, 1996. Invited Lecturer, Florida Statewide Training Conference for HIV/STD/TB, Orlando, Florida, 1996. Invited Lecturer, “STDs – Quo Vadis?” Florida HIV/STD/TB Conference, State of Florida, Orlando, Florida, 1994. Faculty, “Infectious Disease Review” Geriatrics Board Review Course, American Geriatrics Society, Tampa, Florida, 1994. Faculty, “Infectious Disease Review” American College of Physicians, Medical Knowledge Self Assessment Program, Orlando, Florida, 1993. Faculty, “Infectious Disease Review” Geriatrics Board Review Course, American Geriatrics Society, Tampa, Florida, 1992. Invited Lecturer, “STD Update” Statewide AIDS Program Conference, State of Florida Department of Health and Rehabilitative Services, Orlando, Florida, 1992. Faculty, “Infectious Disease Review” Internal Medicine Board Review Course, American College of Physicians, Lake Buena Vista, Florida, 1991. Faculty, “Infectious Disease Review” Medical Knowledge Self-Assessment Program. American College of Physicians, Orlando, Florida, 1987. Local: Invited Lecturer, “MRSA Infection Update” University of South Florida College of Medicine Signature Interdisciplinary Program in Allergy, Immunology, and Infectious Disease Conference, Tampa, FL 2008. Invited Lecturer, “Pneumonia Update” 15th Annual Pulmonary Wintercourse, American Lung Association, Orlando, Florida, 1993. Invited Lecturer, “Infections and Veterans” National Veterans Service Training Program, Clearwater, Florida, 1993. John F. Toney, MD Page 4 CLINICAL ACTIVITIES AND INNOVATION: Board Certification American Board of Internal Medicine, #100706, Nov 11, 1986. Indefinite (Subspecialty in Infectious Diseases) American Board of Internal Medicine, #100706, Sept 11, 1985. Indefinite National Board of Medical Examiners, 1982. Professional Licenses Florida exp. Jan 31, 2017 SCHOLARY ACTIVITIES: Publications Original Publications in Peer-Reviewed Journals or Other Media: 1. Morrison VA, Johnson GR, Schmader KE, Levin MJ, Zhang JH, Looney DJ, Betts RF, Gelb L, Guatelli JC, Harbecke R, Pachucki C, Keay S, Menzies B, Griffin MR, Kauffman CA, Marques A, Toney JF., Boardman K, Su S, Li X, Chan ISF, Parrino J, Annunziato P, Oxman MN. Long-Term Persistence of Zoster Vaccine Efficacy. Clinical Infectious Diseases. 60(6):900-909, 2015. PMID: 25416754 2. Morrison VA, Oxman MN, Levin MJ, Schmader KE, Guatelli JC, Betts RF, Gelb LD, Pachucki CT, Keay SK, Menzies B, Griffin MR, Kauffman CA, Marques AR, Toney JF, Simberkoff MS, Serrao R, Arbeit RD, Gnann JW, Greenberg RN, Holodniy M, Keitel WA, Yeh SS, Davis LE, Crawford GE, Neuzil KM, Johnson GR, Zhang JH, Harbecke R, Chan IS, Keller PM, Williams HM, Boardman KD, Silber JL, Annunziato PW, Shingles Prevention Study Group. Safety of zoster vaccine in elderly adults following documented herpes zoster. Journal of Infectious Diseases. 208(4):559-63, 2013. PMID: 23633406 3. Schmader KE, Oxman MN, Levin MJ, Johnson G, Zhang JH, Betts R, Morrison VA, Gelb L, Guatelli JC, Harbecke R, Pachucki C, S. Keay S, Menzies B, Griffin MR, Kauffman C, Marques A, Toney JF, Keller PM, Li X, Chan ISF, P. Annunziato, for the Shingles Prevention Study Group. Persistence of the Efficacy of Zoster Vaccine in the Shingles Prevention Study and the Short-Term Persistence Substudy. Clinical Infectious Diseases, 55(10):1320–8, 2012. PMID: 22828595 4. Cutaneous Manifestations of HTLV-1 Infection- A Case Report. Cheema A, Highsmith J, McCardle T, Castillo E, Sandin RL, Velez AP, Toney JF, Greene JN. Infectious Disease in Clinical Practice, 20:435437, 2012. 5. Oehler RL, Smith K, Toney JF. Infectious Diseases Resources for the iPhone. Clinical Infectious Diseases, 50:1268–1274, 2010. PMID: 16107233 6. Levin MJ, Oxman MN, Zhang JH, Johnson G, Stanley H, Hayward AR, Caulfield MJ, Irwin MR, Smith JG, Clair J, Chan ISF, Williams H, Harbecke R, Marchese R, Straus SE, Gershon A, Weinberg A, and the Veterans Affairs Cooperative Studies Program Shingles Prevention Study Investigators (Toney JF). Varicella-Zoster Virus–Specific Immune Responses in Elderly Recipients of a Herpes Zoster Vaccine. Journal Infectious Diseases, 197:825–35, 2008. PMID: 18419349 7. Sarna J, Sharma A, Naik E, Toney J, Marfatia YS. Protean manifestations of herpes infection in AIDS cases. Indian J Sex Transm Dis 29:26-8, 2008. 8. Modi M, Sharma A, Marfatia YS, Naik E, Toney J. Late congenital syphilis with stigmata. Indian J Sex Transm Dis 29:32-3, 2008. 9. Tucci VT, Toney JF. Not So Benign: the Clinical Manifestations, Diagnosis, and Treatment of Trichomoniasis in Men. Asian Biomedicine 2:91, 2008. 10. Rolfe NE, Toney JF, Green MR, Sandin RL, Greene JN. Successful Treatment of Mycobacterium fortuitum Osteomyelitis After Allogeneic Bone Marrow Transplantation. Inf Dis Clin Pract 15:339, 2007. 11. Toney JF and Diaz J . Syphilis and Pregnancy. Journal of the Florida Medical Association 90:20, 2006. 12. Oxman MN, Levin MJ, Johnson GR, Schmader KE, Straus SE, Gelb LD, Arbeit RD, Simberkoff MS, Toney JF, et. al. Varicella–Zoster Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults. New England Journal of Medicine 352:2271, 2005. PMID: 15930418 John F. Toney, MD Page 5 13. Toney JF. Skin manifestations of herpesvirus infections. Current Infectious Disease Reports, 7:359, 2005. PMID: 16107233 14. Toney JF. Syphilis serology. Journal of the Florida Medical Association, 89:8, 2005. 15. Toney JF. Syphilis - Dermatologic manifestations. Journal of the Florida Medical Association, 89:16, 2005. 16. Carter WW, Gompf SG, Toney JF, Greene JN, Cutolo EP. Disseminated Acanthamoeba Sinusitis in a Patient With AIDS: A Possible Role for Early Antiretroviral Therapy. AIDS Reader 14:41, 2004. PMID: 14959703 17. Toney JF, Bergen GA. Syphilis Elimination -Deja Vu? Infections in Medicine, 17:619, 2000 18. Toney JF, Montero J. Sexually Transmitted Diseases – Where Do We Go From Here? Infections in Medicine 17:92, 2000. 19. Bittner MJ, Toney JF, Eleftheriou PD, Ribner BS. Randomized, double-blind comparison of oral cefpodoxime and parenteral ceftriaxone in hospitalized adults with community-acquired pneumonia. Journal of Clinical Outcomes Management 6:38, 1999. 20. Bergen GA, Toney JF. Infection versus Colonization in the Critical Care Unit. Critical Care Clinics of North America 14:71, 1998. PMID: 9448979 21. Larkin JA, Lit L, Toney JF. Recognizing and treating syphilis in pregnancy. Medscape Women’s Health 3(1):5, 1998 PMID: 9732090 22. Larkin JA, Lit L, Toney JF. Recognizing and treating syphilis in pregnancy. Medscape Women’s Health. 3:5, 1998. PMID: 9732090 23. Larkin JA, Thomas G, Toney JF. STD interactive case challenge--diagnosing and treating chronic vulvar pain and erythema. Medscape Womens Health. 3:1, 1998. PMID: 9878923 24. Montero JA, Larkin JA, Houston SH, Toney JF. Examining the complex relationship of Human Papillomavirus to cervical dysplasia and carcinoma. Medscape Women’s Health 2:1997. PMID: 9746693 25. Toney JF, Parker MM. New Perspectives on the Management of Septic Shock in the Cancer Patient. Infectious Diseases Clinics of North America 10:239, 1996. PMID: 8803620 26. Toney JF, Larkin JA. Contemporary Strategies for Detecting Chlamydial Infection in Women. Medscape Women’s Health, 1:1, 1996. 27. Larkin JA, Ison MG, Toney JF, Brokamp K. HIV in Women: Recognizing the Signs. Medscape Women’s Health 1:11, 1996. PMID: 9746653 28. Nadler JP, Himelright IM, Greene JN, Toney JF: Clinically Significant HIV Infection in the Elderly. Infectious Diseases in Clinical Practice, 4:304, 1995. 29. Toney JF, Greene JN, Chmel H. Sepsis in the 1990’s - The Treatment of Chaos. Cancer Control, 1:539, 1994. 30. Haight DO, Toney JF, Greene JN, Sandin RL, Vincent AL. Liver Abscess Following Blunt Trauma: A Case Report and Review of the Literature. Southern Medical Journal, 87:811, 1994. PMID: 8052889 31. Hiemenz JW, Toney JF, Hiemenz SK, Greene JN. Prevention of Infection in Patients Undergoing Ablative Chemotherapy and Bone Marrow or Peripheral Blood Stem Cell Transplantation. Cancer Control, 1:269, 1994. 32. Greene JN, Sandin RL, Hiemenz JW, Toney JF. Infectious and Inflammatory Diseases Masquerading as Head and Neck Malignancy. Cancer Control, 1:20, 1994. 33. Sandin RA, Greene JN, Sarzier ID, Himelright IM, Ku K, Toney, JF, and Roberts J. Pelvicoabdominal Actinomycosis Associated with an Intrauterine Contraceptive Device - A Case of Liver Dissemination Mimicking Metastatic Ovarian Cancer. Annals of Clinical and Laboratory Science, 23:448, 1993. John F. Toney, MD Page 6 34. Henry DH, Beall GN, Benson CA, Toney JF, et al. Recombinant Human Erythropoietin in the Treatment of the Anemia Associated with Human Immunodeficiency Virus Infection and Zidovudine Therapy: Overview of Four Clinical Trials. Annals of Internal Medicine, 117:739, 1992. PMID: 1416576 35. Buffington DE, Toney JF. Focus on Temafloxacin: A New Rapidly Absorbed, Extended-Spectrum Fluoroquinolone Antibiotic. Hospital Formulary, 27:241, 1992. 36. Milam MW, Balerdi MJ, Toney JF, Foulis PR, Milam CP, Behnke RH. Epithelioid Angiomatosis Secondary to Disseminated Cat Scratch Disease Involving the Bone Marrow and Skin in a Patient with Acquired Immune Deficiency Syndrome: A Case Report. The American Journal of Medicine, 88:108,1990. PMID: 2301445 37. Yangco BG, Kenyon VS, Halkias KD, Bogel JA, Toney JF, Chmel H. Oral Ciprofloxacin Treatment of Infections in Geriatric Patients. Clinical Therapeutics, 11: 503, 1989. PMID: 2776166 38. Yangco BG, Kenyon VS, Halkias KD, Toney JF, Chmel H. Comparative Evaluation of Safety and Efficacy of Cefmetazole and Cefoxitin in Lower Respiratory Tract Infections. Journal of Antimicrobial Chemotherapy, 23: 39, 1989. PMID: 2656626 39. Yangco BG, Kenyon VS, Halkias KD, Bogel JA, Toney JF, Chmel H. Oral Ciprofloxacin in the Treatment of Infections in Geriatric Patients. Reviews of Infectious Diseases, 11:1112, 1989. PMID: 2776166 40. Walker JL, Gustke K, Toney JF, Sinnott JT. Centrifugation of Antibiotic Impregnated Bone Cement. Orthopedics, 11: 891, 1988. PMID: 3387336 Corporate Authorship of Multicenter Trials: 1. Bone RC, Balk RA, Fein AM, Perl TM, Wenzel RP, Reines HD, Quenzer RW, Iberti TJ, Macintyre N, Schein RMH, E5 Sepsis Study Group (Toney, JF Site Co-I). A Second Large Controlled Clinical Study of E5, a Monoclonal Antibody to Endotoxin: Results of a Prospective, Multicenter, Randomized Controlled Trial. Critical Care Medicine, 23:994,1995. PMID: 7774238 2. Greenman RL, Schein RMH, Martin MA, et al. (Toney JF Site Co-I) A Controlled Clinical Trial of E5 Murine Monoclonal IgM Antibody to Endotoxin in the Treatment of Gram-Negative Sepsis. The XOMA Sepsis Group. JAMA, 266:1097, 1991. PMID: 1865542 Book Chapters: 1. Toney JF. Related syndromes and less common STD (bacterial vaginosis, chancroid, granuloma inguinale). In Jong EC and Stevens DL eds. Netter's Infectious Diseases, Elsevier Saunders, Pennsylvania 2012, pp 362-370. 2. Toney JF. Sexually Transmitted Diseases. In: Beal, Orrick, Alfonso, and Rathore eds. HIV/AIDS Primary Care Guide, Crown House Publishing, Vermont, 359, 2006. Electronic chapter update 2007 published and available at http://www.faetc.org/Guide/index.asp 3. Toney JF. Nongonococcal Urethritis. In: Rakel and Bope eds. Conn’s Current Therapy 2005, Elsevier Saunders, Pennsylvania, 2005, pp 857-858. 4. Toney JF. Sexually Transmitted Diseases. In: Baddour and Gorbach eds. Therapy of Infectious Diseases, Elsevier, New York, 2002, pp 469-491. 5. Toney JF, Bergen GA. Sexually Transmitted Diseases. In: Steinhart, Orrick, and Simpson eds. HIV/AIDS Primary Care Guide, University of Florida Press, Florida, 359, 2002. 6. Bergen GA, Toney JF. Colonization versus Infection in the Critical Care Unit. In: Cunha ed. Infectious Diseases in Critical Care Medicine, Marcel Dekker, Inc., New York, 17, 1998. Other: 1. Katayama M, Toney JF, Gompf SG, Oehler RL. Case #13015: 2013 IDWeek Case: A man in his eighties from Puerto Rico with productive cough, subjective fever, and dizziness. [Internet]. Partners Infectious Disease Images. Available from: http://www.idimages.org/idreview/case/caseid=491. 2013. 2. Toney JF. Collaborator and content reviewer, Historic Black Colleges and Universities (HBCU) Medical School STD Curriculum Initiative Conference, Yolanda Wimberly, MD PI, Morehouse School of John F. Toney, MD Page 7 Medicine – creation of medical school curriculum (STI Curriculum, Education, and Research – STICER [www.hbcusticer.com]) to enhance STI education to medical students and residents. 2009 – 2011. 3. Toney JF. Consultant, CDC Syphilis Elimination & STD Disparities Unit Division of STD Prevention, NCHHSTP STD/STI Framing Conversation Report – "Framing Conversation on Sexually Transmitted Diseases Disparities: What’s wrong? Why does it matter? And, What should be done about it?” (located at www.cdc.gov/STD/health-disparities/Framing_Report.pdf). March 2010 4. Toney JF. Multiple infectious disease-related podcasts (located at http://www.idpodcasts.net) 2007present. 5. Toney JF. HIV/AIDS Update (CME Webcast), University of South Florida College of Medicine, Tampa, Florida, 2005. 6. Toney JF. CDC National Network of STD/HIV Prevention Training Center STD Teaching Modules – Primary Editor (Pelvic Inflammatory Disease); Contributing Editor (Cervicitis, Chancroid, Chlamydia, Gonorrhea, Hepatitis, HIV, HPV, Syphilis, Urethritis, Vaginitis, Clinical Approach to the STD Patient). 7. Toney JF. CDC’s “STD 101 in a Box – Ready to Use Presentations” Developed the STD 101 Clinician PowerPoint Presentation (available at http://www2a.cdc.gov/std101/default.asp), 2003, updated 2004 and 2006. 8. Toney JF. Southeast Region (formerly Florida) STD/HIV Prevention Training Center (http://www.septc.org) – Site developed/published/maintained 2000-2012 (100% effort). 9. Toney JF. Sexually Transmitted Diseases Update. Southern Medical Association Lecture-on-Line Program (http://www.sma.org/lectureonline/index.htm). 1999-2001. 10. Toney JF, Hiemenz JH. Treatment of Documented Candidemia Vs. Presumptive Therapy. Medical Outlook (audiocassette journal), Vol. 1, No. 2; 1995. 11. Toney JF. HIV/AIDS Update (audiotape), American Board of Quality Assurance and Utilization Review Physicians, Tampa, Florida, 1995. 12. Toney JF. PPNG, TRNG - More Resistant GC. Infections in Medicine 12:607, 1995. (editorial) 13. Toney JF. Sexually Transmitted Diseases - Genital Lesions. Southern Medical Association Dial Access Program, 1994. 14. Toney JF. Sexually Transmitted Diseases - Urethral Drainage. Southern Medical Association Dial Access Program, 1994. 15. Holt DA, Toney JF, Sinnott JT. Reviews of Cephalosporins and Aztreonam. Southern Medical Association Dial Access Program, 1993. 16. Toney JF, Walker RM, Mertzman R, et al. The Challenge to Care - An HIV/AIDS Study Guide (with accompanying video tape), Florida AIDS Education and Training Network, Tampa, Florida, 1993. 17. Toney JF. HIV Patient Management Experience. Practice to Practice, 1:10, 1993. 18. Toney JF. HIV/AIDS Update (audiotape) University of South Florida College of Medicine, Tampa, Florida, 1991. 19. Toney JF, Sinnott JT, Ivey P, Goldhagen P. Infections in Bone Marrow Transplantation. Infectious Disease Newsletter, 8:1, 1989. ABSTRACTS: Poster Presentations: 1. Oehler RL, Toney JF, Gompf SG, Ruisz M, Vega, V, Lezama J, Dunn Y. Wrong Time, Wrong Place – A Hospital-Associated Outbreak of Influenza A in the Summer. IDWeek Annual Meeting, New Orleans, LA. October 26-30, 2016 2. Morano JP, Paruolo J, Klinkova O, Pandya S, Ho M, Dahl J, Aslam S, Toyinbo P, Lapcevic W, Cheung L, Toney JF. Clinical Treatment Outcomes and Prescribing Patterns Among Hepatitis C+ and HIV+ Veterans: Implementation Science and Quality Improvement Using Retrospective Cohort Analysis. James A. Haley Veterans Hospital Research Day, May 26, 2016. John F. Toney, MD Page 8 3. Toney JF*, Fries Narla, Rivera R, Mastorides S, Oehler R. Reduction in Contaminated Blood Culture Rates and Associated Costs as an Antimicrobial Stewardship Program Activity. James A. Haley Veterans Hospital Research Day, May 5, 2015. 4. Toney JF*, Carlucci M, Ruisz M, Gompf S. Sustained Reduction in Catheter-associated Urinary Tract Infection (CAUTI) Rates Using a Collaborative Program Approach. James A. Haley Research Day, May 5, 2015. 5. Toney JF, Fries Narla, Rivera R, Mastorides S, Oehler R. Reduction in Contaminated Blood Culture Rates and Associated Costs as an Antimicrobial Stewardship Program Activity. IDWeek Annual Meeting, Philadelphia, PA, 2014. 6. Toney JF, Carlucci M, Ruisz M, Gompf S. Sustained Reduction in Catheter-associated Urinary Tract Infection (CAUTI) Rates Using a Collaborative Program Approach. IDWeek Annual Meeting, Philadelphia, PA, October 8-12, 2014. 7. Honebein PC, Goldsworthy RC, Fortenberry JD, Toney JF, Kollar LM. Building Providers’ interpersonal skills through an online, constructivist learning experience. American Public Health Association (APHA) 136th Annual Meeting, San Diego, CA, 2008. 8. Toney JF, Doss CE. Collaborative efforts – STD/HIV Conference at Morehouse School of Medicine. 4TC Collaborative Meeting (CDC, HRSA, OPA, OPHS/OHAP, and SAMSA). New Orleans, LA, 2008. 9. Honebein PC, Goldsworthy RC, Fortenberry JD, Toney JF, Kollar LM. Just Ask! A Constructivist, Webbased Approach for Provider STD Skills Training. CDC National STD Prevention Conference, Chicago, Illinios, 2008. 10. Toney JF, Leon P, Oehler RL, Gompf, SG. Infectious Complications of Acinetobacter baumanii in Wounded Iraqi Soldiers at a VA Medical Center. Infectious Diseases Society of America, San Francisco, 2005 11. Toney JF, Oehler RL, Mastorides SM, Gompf SG, Sinnott JT. Comparison of a Treponemal IGG EIA Assay versus Conventional RPR Testing in Patient Screening for the Diagnosis Of Treponema Pallidum Infection. 16th Bienneal Meeting of the International Society for Sexually Transmitted Diseases Research, Amsterdam, Netherlands, 2005 12. Toney JF, Schmitt K, Powelson M, Detis J, Montero JA. Assessment of STD and HIV Education and Skills in a Variety of Clinical Providers and 1998 Recent Graduates. 2000 CDC National STD Prevention Conference, Milwaukee, Wisconsin, 2000. 13. Montero JA, Schmitt K, Powelson M, Detis J, Toney JF. Assessment of STD and HIV Education and Skills in a Variety of Clinical Providers. Infectious Diseases Society of America, New Orleans, Louisiana, 2000. 14. Ganguly R, Lenox B, Toney JF, Quiroz E, Poblete S. Risk Factors And HIV Testing In A Veteran Population Infectious Diseases Society of America, New Orleans, Louisiana, 2000. 15. Toney JF, Bittner MJ, Ribner BS, Eletheriou PD. Comparison of Oral Cefpodoxime Proxetil with Parental Ceftriaxone in the Treatment of Acute Moderately Severe Community-Acquired Pneumonia. American Society of Microbiology, Miami, Florida, 1997. 16. Ganguly R, Sinnott JT, Houston S, Toney JF, Holt D, Cobian L. Hepatitis B Virus Vaccine: A measure Against Occupationally Acquired Infection. Infectious Diseases Society of America Annual Meeting, San Francisco, California. 1997 17. Toney JF, Bergen GA, Sinnott JT, Vincent AL, Ganguly RA, Schmitt K, Wroten JE. Sexually Transmitted Diseases Attitudes and Knowledge in County Public Health Care Units. National CDC STD Prevention Conference, Tampa, Florida. 1996. 18. Nadler JP, Toney JT, Holt DA, Seeley P. Toxicities in Patients Receiving Retrovir, HIVID, and Interferon-Alfa for HIV Infection. 6th International Congress for Infectious Diseases, Prague, Czech Republic, 1994. John F. Toney, MD Page 9 19. Toney JF, Callahan CM, Vincent AL, Bergen GA. Sexually Transmitted Diseases Attitudes and Knowledge in Trainees at a University Medical School. Infectious Diseases Society of America Meeting, Orlando, Florida. 1994. 20. Toney JF, Callahan CM, Vincent AL, Bergen GA. Assessment of Sexually Transmitted Diseases Attitudes and Knowledge in University Medical School Trainees. American College of Physicians Scientific Meeting, Tampa, Florida. 1994. (Received “Outstanding Poster Presentation” award) 21. Vila IA, Greene JN, Toney JF. Q Fever in an Avian Pathologist: Atypical Presentation of an Atypical Pathogen. American College of Physicians Florida Scientific Meeting, Tampa, Florida. 1994. 22. Nadler JP, Toney JT, Holt DA, Seeley P. Comparison of Retrovir, HIVID, and Wellferon versus Retrovir and HIVID in HIV Infected Patients Without AIDS. Interscience Conference on Antimicrobial Agents and Chemotherapy, October, 1993. 23. Seeley P, Toney JT, Nadler JP, Holt DA. Development of a Newsletter to Provide New Information to Study Participants in a Long-Term HIV Clinical Trial. 6th Annual Conference of the Association of Nurses in AIDS Care, Los Angeles, CA, 1993. 24. Toney JF, Halkias KD: Susceptibilities of Methicillin-Resistant Staphylococcus to Four Antibiotics. USF College of Medicine Faculty Research Day, 1992. 25. Nadler JP, Toney JF, Greene JN: Clinically Significant HIV Infection in the Elderly. American College of Physicians Scientific Meeting, Tampa, FL, 1992. 26. Yangco BG, Gelfand MS, Kenyon VS, Craft RB, Toney JF, Simmons BP, and Chmel H. Cefepime vs. Ceftazidime Treatment of Infections in Hospitalized Patients. Annual Meeting of the American Society for Microbiology, Anaheim, CA. 1990. 27. Henry DH, Toney JF, et al. r-HuEPO in Anemia Associated with HIV Infection and AZT Therapy Safety and Efficacy Analysis of Four Multicenter Trials, Interscience Conference on Antimicrobial Agents and Chemotherapy, Atlanta, GA, 1990. 28. Yangco BG, Halkias KD, Rushton TC, Toney JF and Chmel H. In Vitro Activity of Aztreonam, Ciprofloxacin, Minocycline, Rifampin, and Trimethoprim-Sulfamethoxazole, Alone and in Combination, Against Xanthomonas maltophilia. 29th Interscience Conference on Antimicrobial Agents and Chemotherapy, Houston, TX, 1989. 29. Martin MA, Wenzel RP, Gorelick KJ, Toney JF et al. Prospective National Study of Gram-Negative Bacterial (GNB) Sepsis - Natural History in the 1980s. 29th Interscience Conference on Antimicrobial Agents and Chemotherapy, Houston, TX, 1989. 30. Toney JF, Halkias KD, Yangco BG, Chmel H. Susceptibilities of Methicillin Resistant Staphylococcus to Four Antibiotics. Society for Hospital Epidemiologists of America Annual Meeting, Baltimore, MD, 1989. 31. Yangco BG, Gelfand MS, Kenyon VS, Craft RB, Simmons BP, Toney JF, Bogel J & Chmel H. Cefepime (CFP) in the Treatment of Infections in Hospitalized Patients. Annual Meeting of the American Society for Microbiology, New Orleans, LA, 1989. 32. Yangco BG, Kenyon V, Toney JF, Chmel H: Comparative Evaluation of Safety and Efficacy of Cefmetazole vs. Cefoxitin in Infections of Hospitalized Patients. Interscience Conference on Antimicrobial Agents and Chemotherapy, New York City, NY. October 1987. 33. Yangco BG, Sikes E, Palumbo J, Toney JF, Holder CD, Cullison JP: Cefpiramide in the Therapy of Infections in Hospitalized Patients Interscience Conference on Antimicrobial Agents and Chemotherapy, Minneapolis, Minnesota, 1986. Oral Presentations: 1. Toney JF, Sinnott JT, Martin RB, Lewis JD, Crockett LK. Rapid Communication of Emerging Infectious Threats to Florida Medical Professionals. International Conference on Emerging Infectious Diseases, Atlanta, Georgia, 2004. 2. Walker JL, Gustke K, Toney JF, Sinnott JT: Centrifugation of Antibiotic Impregnated Bone Cement. Eastern Orthopaedic Association Meeting, Southampton, Bermuda, November 1986. John F. Toney, MD Page 10 Grants: Past Grant Support 1. Zhu Y PI, Toney, JF Co-I Biostatistics in Medical & Health Research via Clinical Trials and Epidemiology (1T15 HL097780-01) NIH/National Heart, Lung, Blood Institute; 08/20/2009 - 07/31/2012; Total budget $793,640. To conduct summer institute for training in biostatistics for senior undergraduate students and beginning graduate students selected from a national pool and thereby to promote Biostatistics as a career choice for US students. 2. Toney JF (PI), Schmitt K. Sexually Transmitted Diseases/Human Immunodeficiency Virus Prevention Training Centers (Funding Opportunity Number: PS06-606 R30 Cooperative Agreement) Centers for Disease Control and Prevention (CDC), 2006. (80% effort) $369,000 annually, renewed 2007, 2008, 2009, 2010. 3. Toney JF (PI), Gompf SG, Oehler RA. VA Cooperative grant CSP #403(c) Shingles Prevention Study (SPS) Long Term Persistance Study (5-year study). 2006-2010 (95% effort) $517,000 total. 4. Toney JF (PI), Gompf SG, Oehler RA. VA Cooperative grant CSP #403(b) Shingles Prevention Study (SPS) Placebo Patient Vaccination Study. 2005-2006 (95% effort) $107,079 total. 5. Toney JF, (PI) Schmitt K, Wroten J. Sexually Transmitted Diseases/Human Immunodeficiency Virus Prevention Training Centers [Program Announcement 00031]. Centers for Disease Control and Prevention (CDC), 2000. (60% effort) $312,000 annually, renewed 2001, 2002, 2003, 2004, 2005 with addition contract $100,000 (90% effort). ($1.66 million for 2000-2005 period) 6. Toney JF (PI). Sexually Transmitted Diseases (STD) Prevention Training Center of Florida. Florida Dept. of Health and Rehabilitation Services (HRS). 1988, renewed 1989 - 2000. (90% effort) $140,000 – 180,000 yearly ($1.8 million over 12 years) 7. Toney JF (PI). VA Cooperative grant CSP #403 Shingles Prevention Study (SPS). 1998 - 2004 (100% effort) $750,000 total. 8. Toney JF, (PI) Bergen GA. Ryan White Title I Grant - Primary Care for HIV-Infected Patients. Florida Department of Health and Rehabilitative Services (HRS), 1994. Grant #: 94-1336, renewed, 1995. (50% effort). $10,000 yearly. Pharmaceutical Grants - Principal Investigator: 1. Toney JF, Gompf SG, Oehler RA. A Phase II, Multicenter, Randomized, Double-Mask, Double-Dummy Study Comparing the Efficacy and Safety of Peramivir Administered Intravenously Once Daily versus Oseltamivir Administered Orally Twice Daily in Adults with Acute Serious or Potentially Life-Threatening Influenza. Biocryst. 2008 2. Toney JF, Gompf SG, Oehler RA. Intravenous Telavancin for Complicated Skin and Soft Tissue Infections. Theravance. 2004 – 2006. (85% effort) 3. Toney JF, Gompf SG, Oehler RA, Cutolo EP, Lazama J. Intravenous Telavancin for Uncomplicated Staphylococcus aureus Bacteremia (Phase II Study). Theravance. 2003 – 2006. (85% effort) 4. Toney JF, Bergen GA, Nadler JP, Dominguez E, Oehler RA, Poblete SJ, and Seeley P. An OpenLabel, Multicenter, Safety and Efficacy Study of 5% Topical Imiquimod Cream in the Treatment of Visible, External Genital/Perianal Warts in Male and Female Patients. 3M. 1998 (75% effort) 5. Toney JF, Bergen GA, Linezolid (PNU-100766) in the Treatment of Gram Positive Bacteremia: An Open Label Phase II Study of Intravenous Therapy with Optional Oral Continuation. Pharmacia & Upjohn. 1998 (75% effort) 6. Toney JF, Bergen GA, Nadler JP, Dominguez E, Oehler RA, Poblete SJ. A Randomized Double-Blind Study of Safety, Virologic and Immunological Effects of Stavudine plus 3TC versus Zidovudine plus 3TC in HIV-Infected Subjects Following at Least Six (6) Months of Zidovudine Therapy. Bristol-Meyers Squibb. 1996. (75% effort) 7. Toney JF, Bergen GA, Nadler JP, Dominguez E, Oehler RA, Poblete SJ, and Seeley P. An Open Comparative Multicenter Study of Intravenous Itraconazole followed by Itraconazole Oral Solution John F. Toney, MD Page 11 versus Intravenous Fluconazole followed by Oral Fluconazole Tablets in the Treatment of Candidemia in Non-Neutropenic Patients. Janssen. 1996. (80% effort) 8. Toney JF, Bergen GA, Nadler JP, Dominguez E, Oehler RA, Poblete SJ, and Seeley P. A Phase III, Double-Blinded, Placebo-Controlled Trial of Recombinant Human Granulocyte-Macrophage ColonyStimulating Factor (rhu-GM-CSF) in Patients with Advanced HIV Disease. Immunex. 1996. (75% effort) 9. Toney JF, Klotch D, Buffington DE. An Open Noncomparative, Multicenter Study of RP 64206 (Sparfloxacin) in the Treatment of Acute Maxillary Sinusitis. Rhone - Poulenc Rorer. 1995. (50% effort) 10. Toney JF, Bergen GA. A Multicenter Randomized Comparative Trial with Ampicillin/Sulbactam Plus Oral Azithromycin or Ampicillin/Sulbactam Plus Intravenous Erythromycin in the Treatment of Moderately Ill Hospitalized Subjects with Community-Acquired Pneumonia. Pfizer. 1995. (75% effort) 11. Toney JF, Greene JN, Holt DA, Seeley P. Comparison Of Oral Cefpodoxime Proxetil With Parenteral Ceftriaxone In The Treatment Of Acute Community-Acquired Pneumonia. Upjohn. 1994. (75% effort) 12. Toney JF, Buffington DE, DeSilva K, McCormick M, Rodriguez CL, Seeley P. Prospective, DoubleBlind, Controlled, Randomized, Multicenter Comparison Of The Safety And Efficacy Of Intravenous Ciprofloxacin vs. Intravenous Imipenem For The Treatment Of Patients With The Sepsis Syndrome. Miles. 1994. (90% effort) 13. Toney JF, Sinnott JT, Holt D, Greene JN. An Open-Label, Comparative, Safety, Tolerance and Efficacy Study of Parenteral Piperacillin/ Tazobactam plus Tobramycin vs. Imipenem/Cilastatin plus Tobramycin for the Treatment of Hospitalized Patients with Septicemia. Lederle. 1993. (95% effort) 14. Toney JF, Sinnott JT, Holt D, Greene JN. A Multicenter, Active-Controlled, Randomized Study to Evaluate the Safety and Efficacy of Oral Levofloxacin vs. Cefaclor in Acute Exacerbations of Chronic Bronchitis. Ortho. 1993. (80% effort) 15. Toney JF, Holt D, Greene JN. A Trial of Trental (Pentoxifylline) 1800mg or 2400mg Daily vs Placebo for the Prevention of the Nephrotoxicity Associated with Amphotericin B in Fungal Disease. HoechstRoussel. 1993. (90% effort) 16. Toney JF, Sinnott JT, Holt D, Greene JN. Oral Temafloxacin vs. Intravenous Imipenem-Cilastatin Sodium in Serious Skin and Deep Tissue Infections. Abbott. 1992. (85% effort) 17. Toney JF, Sinnott JT, Holt D, Greene JN. A Double-Blinded, Multicenter Comparative Study of the Safety and Efficacy of Intravenous Cefodizime vs. Intravenous Ceftriaxone in the Treatment of Community-Acquired Pneumonia. Fujisawa. 1992. (85% effort) 18. Toney JF, Sinnott JT, Holt D, Greene JN. Ampicillin Plus Sulbactam in the Treatment of Acute Episodes of Urinary Tract Infections of Ampicillin-Resistant Bacterial Etiology. Roerig. 1992. (50% effort) 19. Toney JF, Yangco BG, Chmel H: A Double-Blind, Placebo-Controlled Study with Open-Label Follow-up to Determine the Safety and Efficacy of Subcutaneous Doses of Recombinant Human Erythropoietin (rHuEPO) in AIDS Patients with Anemia Induced by Their Disease and AZT Therapy. Ortho. 1991. (85% effort) 20. Toney JF, Yangco BG, Chmel H: Megestrol Acetate in Acquired Immunodeficiency Syndrome (AIDS). Bristol-Meyers. 1991. (90% effort) 21. Toney JF, Yangco BG, Chmel H: Chlamydia One-Dose Azithromycin (CODA) Trial, Pfizer. 1991. (75% effort) 22. Toney JF, Yangco BG, Chmel H: Evaluation of Aztreonam in the Treatment of Diabetic Foot Ulcers. Squibb. 1989. (85% effort) 23. Toney JF, Yangco BG, Chmel H: Fleroxacin (Ro 23-6240) Once Daily in the Intravenous Therapy of Serious Bacterial Infections: An Open, Multicenter Study. Roche. 1989. (95% effort) John F. Toney, MD Page 12 Pharmaceutical Grants Co- Investigator: 1. Gompf SG, Toney JF, Oehler RA, Nadler JP. Randomized Double-Blind Comparative Study of Pegasys (Peginterferon α-2a) and Copegus (Ribavirin) Given for 16 vs. 24 Weeks in Patients with Genotype 2 or 3 Hepatitis C Infection. Roche. 2004. (5% effort) 2. Nadler, JP, Toney JF, Bergen GA, Dominguez ER. A Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, and Antiretroviral Activity of DMP 266 alone or in Combination with Open-Label Zidovudine (ZDV) and Lamivudine (3TC) in HIV-Infected Patients. DuPont Merck. 1996. (20% effort) 3. Nadler JP, Toney JF, Holt DA, Villanueva LP. A Randomized Trial to Evaluate the Safety and Efficacy of Combination Therapy with Retrovir and HIVID vs. Retrovir, HIVID, and Wellferon for the Treatment of HIV Infection. Burroughs-Wellcome. 1995. (20% effort) 4. Sinnott JT, Toney JF. Hurst JM, Dillion KR, Buffington DE, Greene JN, Holt DA, Cancio M, Centocor: HA-1A Efficacy in Septic Shock Trail (CHESS Trial). Centocor. 1992. (15% effort) 5. Yangco BG, Chmel H, Toney JF. A Comparison of 2', 3' - Dideoxyinosine [ddI] and Zidovudine in Therapy of Patients with AIDS or AIDS Related Complex. Bristol Myers. 1991. (30% effort) 6. Yangco BG, Chmel H, Toney JF. A Multicenter Open Randomized Comparative Study of Meropenem (ICI 194,660/SM 7338) and Ceftazidime Alone or Ceftazidime Plus an Aminoglycoside in the Treatment of Lower Respiratory Infections. Stuart. 1991. (25% effort) 7. Yangco BG, Chmel H, Toney JF. An Open Label Study to Evaluate Long-Term Safety and Efficacy of Betaseron in Advanced ARC and AIDS Subjects. Berlex. 1991. (30% effort) 8. Yangco BG, Chmel H, Toney JF. Rifabutin Therapy for the Prevention of Mycobacterium avian Complex (MAC) Bacteremia in AIDS Patients with CD4 Counts < 200. Adria. 1991. (35% effort) 9. Chmel H, Yangco BG, Toney JF. A Multicenter, Double-Blind, Randomized, Comparative Study of Temafloxacin Versus Ceftazidime in the Treatment of Bacterial Pneumonia in Hospitalized Patients, Abbott. 1991. (35% effort) 10. Chmel H, Toney JF, Yangco BG, Cullison JP, Cancio MR, Milam MW Holt DA. Multicenter Comparison of Fluconazole and Amphotericin B as Treatment for Acute Cryptococcal Meningitis. Roerig-Pfizer. 1991. (35% effort) 11. Chmel H, Toney JF, Yangco BG. Multicenter Evaluation of Fluconazole as Treatment for Acute Cryptococcal Meningitis in Patients who have Failed to Respond or have Experienced Unacceptable Toxicity During Treatment with Amphotericin B. Pfizer. 1991. (30% effort) 12. Chmel H, Toney JF, Yangco BG, Cullison JP, Cancio MR, Milam MW, Holt DA. Multicenter Comparison of Fluconazole and Amphotericin B as Maintenance Treatment for the Prevention of Relapse of Cryptococcal Meningitis in Patients with Acquired Immunodeficiency Syndrome. RoerigPfizer. 1991. (35% effort) 13. Yangco BG, Chmel H, Toney JF, Cullison JP, Cancio MR, Milam MW, Holt DA. A Randomized Open Study of Teicoplanin vs. Cefazolin in the Treatment of Moderate to Severe Skin and Soft Tissue Infections Caused by Gram-Positive Bacteria. Merrell Dow. 1990. (10% effort) 14. Chmel H, Toney JF, Yangco BG, Cullison JP, Cancio MR, Milam MW, Holt DA. Ciprofloxacin IV/PO in the Management of Febrile Granulocytopenic Cancer Patients with Suspected Infection. Miles. 1990. (20% effort) 15. Yangco BG, Toney JF, Chmel H. Comparative Study of Cefepime and Ceftazidime in the Treatment of Patients with Community Acquired Pneumonia. Bristol-Myers. 1990. (30% effort) 16. Yangco BG, Toney JF, Chmel H. Comparative Study of Cefepime vs. Ceftazidime in the Treatment of Patients with Serious Infections of the Skin and Skin Structures. Bristol-Myers. 1990. (40% effort) 17. Yangco BG, Chmel H, Toney JF. Comparative Study of Cefepime vs. Ceftazidime in the Treatment of Patients with UTI's. Bristol - Myers. 1990. (30% effort) John F. Toney, MD Page 13 18. Yangco BG, Chmel H, Toney JF. A Phase III Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Betaseron in AIDS and Advanced ARC Patients Receiving a Reduced Dose AZT Regimen. Berlex. 1990. (20% effort) 19. Chmel H, Yangco BG, Toney JF. A Prospective, Controlled, Randomized Clinical Trial of Oral Ciprofloxacin as Continuation Therapy of Lower Respiratory Tract Infection in Hospital Patients. Miles. 1990. (20% effort) 20. Chmel H, Yangco BG, Toney JF. A Double-Blind Randomized Placebo Controlled Group Comparative Study of the Safety and Efficacy of XOMEN-E5 in Patients with Suspected Gram Negative Sepsis. Xoma. 1990. (35% effort) 21. Yangco BG, Chmel H, Toney JF. A Randomized, Double-Blind Placebo-Controlled Evaluation of Mupirocin Calcium Ointment for the Eradication of Nasal Mucosa Carriage of Staphylococcus aureus in Health Care Volunteers. Smith Kline. 1990. (15% effort) 22. Yangco BG, Chmel H, Toney JF. The Use of Ampligen in the Treatment of AIDS-Related Complex (ARC) Pilot #4N. DuPont. 1990. (30% effort) 23. Yangco BG, Chmel H, Toney JF. A Study of the Safety and Efficacy of Ampligen in Combination with Ganciclovir in Patients with CMV Retinitis. DuPont. 1990. (30% effort) 24. Yangco BG, Toney JF, Chmel H, Cullison JP, Cancio MR, Milam MW, Holt DA. Treatment of Community Acquired Pneumonia with Intravenous Trospectomycin. Upjohn. 1990. (10% effort) 25. Yangco BG, Chmel H, Toney JF, Cullison JP, Cancio MR. A Randomized Blinded Comparative Study of Teicoplanin vs. Vancomycin in the Treatment of Vascular-Access Associated Bacteremia/Septicemia Caused by Gram-Positive Bacteria. Merrell Dow. 1990. (20% effort) 26. Yangco BG, Chmel H, Toney JF, Cullison JP, Cancio MR: A Multicenter Comparative Trial of BMY28100 vs. Cefaclor in the Treatment of Mild to Moderate Skin and Skin Structure Infections. BristolMyers. 1990. (20% effort ) 27. Yangco BG, Chmel H, Toney JF, Cullison JP, Cancio MR, Milam MW, Holt DA. A Randomized, Controlled Study of Enoxacin (IV followed by Oral) vs. Cefotaxime in the Treatment of Patients with Skin and Skin Structure Infections. Warner-Lambert. 1989. (10% effort) 28. Yangco BG, Toney JF, Chmel H. A Multicenter Controlled of Ampligen in Patients with AIDS-Related Immune Dysfunction. DuPont. 1989. (40% effort) 29. Yangco BG, Toney JF, Chmel H. A Multicenter Study of the Efficacy and Safety of Ampligen in Patients with AIDS. DuPont. 1989. (30% effort) 30. Yangco BG, Toney JF, Chmel H. A Double-Blind Comparison of Small Particle Aerosol Administration of Ribavirin and Placebo in Patients with Influenza Virus Infections. Viratek. 1989. (10% effort) 31. Yangco BG, Toney JF, Chmel H. Comparative Study of Timentin with Gentamicin/Clindamycin in the Treatment of Hospitalized Patients with Intra-Abdominal Infections. Beecham. 1989. (30% effort) 32. Yangco BG, Toney JF, Chmel H. Study of Cefpirome vs. Ceftriaxone in the Treatment of Patients with Skin and Soft Tissue Infections. Hoechst-Roussel. 1989. (30% effort ) 33. Yangco BG, Toney JF, Chmel H. Phase II, Open-Label, Parallel Group, Multicenter, Dose-Finding Study to Evaluate 3 Dose Levels of Orally Administered Cefpodoxime Proxetil) in Patients with UTI's. Sankyo USA Corp. 1989. (20% effort) 34. Yangco BG, Chmel H, Toney JF, Cullison JP, Cancio MR. A Randomized, Controlled Trial of Enoxacin (IV Followed by Oral) vs. Ceftazidime in the Treatment of Hospitalized Patients with Gram-Negative Bacterial Infections of the Lower Respiratory Tract. Parke-Davis. 1989. (20% effort) 35. Yangco BG, Toney JF, Chmel H. Study of Cefpirome vs. Ceftazidime in the Treatment of Patients with UTIs. Hoechst-Roussel. 1989. (30% effort) 36. Yangco BG, Chmel H, Toney JF, Cullison JP, Cancio MR, Milam MW, Holt DA. A Multicenter Comparative Trial of BMY-28100 vs. Cefaclor in the Treatment of Acute and Uncomplicated Urinary Tract Infections. Bristol-Myers. 1989. (20% effort) John F. Toney, MD Page 14 37. Yangco BG, Chmel H, Toney JF, Cullison JP, Cancio MR, Milam MW, Holt DA. Multicenter Trial to Determine the Safety and Efficacy of Antiendotoxin Antibody XMMEM-0E5 in the Treatment of Patients with Suspected Gram-Negative Bacteremia or Endotoxemia. Roerig. 1988. (30% effort) 38. Yangco BG, Chmel H, Toney JF, Cullison JP, Cancio MR. Enoxacin vs. Carbenicillin in the Treatment of Prostatitis. Parke-Davis. 1988. (20% effort) 39. Yangco BG, Chmel H, Toney JF, Cullison JP, Cancio MR, Milam MW, Holt DA. A Phase II MultiInvestigational Non-Comparative Study of BMY-28142 in the Treatment of Urinary Tract, Lower Respiratory Tract and Skin and Skin Structures. Bristol-Myers. 1988. (15% effort) 40. Yangco BG, Sinnott JT, Holder CD, Toney JF, Cullison JP. An Open, Randomized Multicenter Evaluation of Ceftazidime Sodium Carbonate and Ceftazidime L-Arginine in the Treatment of Bacterial Infections of the Skin and Skin Structures and Blood. Glaxo. 1987. (20% effort) 41. Yangco BG, Sinnott JT, Holder CD, Toney JF, Cullison JP. Comparison of Intravenous Cefmetazole and Cefoxitin in the Treatment of Urinary Tract Infections. Upjohn. 1987. (20% effort) 42. Sinnott JT, Yangco BG, Toney JF, Holder CD. A Multicenter Study Comparing Intravenously Cefpiramide and Ceftizoxime in the Treatment of Hospitalized Patients with Infections Caused by Susceptible Aerobic and Anaerobic Bacteria. Wyeth. 1986. (25% effort) 43. Yangco BG, Sinnott JT, Holder CD, Toney JF. A Randomized, Blinded Study Comparing Intravenously Cefpiramide and Cefoperazone in the Treatment of Hospitalized Patients with Infections Caused by Susceptible Aerobic and Anaerobic Bacteria. Wyeth. 1986. (25% effort) 44. Yangco BG, Sinnott JT, Holder CD, Toney JF, Cullison JP. Comparison of Intravenous Cefmetazole and Cefoxitin in the Treatment of Lower Respiratory Tract Infections. Upjohn. 1986. (20% effort) 45. Yangco BG, Sinnott JT, Holder CD, Toney JF, Cullison JP. A Multicenter Randomized Comparison of Cefuroxime Axetil and Augmentin in the Treatment of Lower Respiratory Tract Infections. Glaxo. 1986. (20% effort) 46. Yangco BG, Sinnott JT, Holder CD, Toney JF, Cullison JP. Comparison Study of Ceftazidime vs. an Anti-Pseudomonal Penicillin Plus an Aminoglycoside in the Treatment of Hospital-Acquired Bacterial Pneumonia. Smith Kline and French. 1986. (20% effort) 47. Yangco BG, Sinnott JT, Holder CD, Toney JF, Cullison JP. Multicenter Randomized Study to Compare Ofloxicin vs. Amoxicillin in the Treatment of Respiratory Tract Infections in Adults. Ortho. 1986. (20% effort) 48. Yangco BG, Sinnott JT, Holder CD, Toney JF. A Comparative Multicenter Evaluation of Cefadroxil and Amoxicillin Therapy in the Treatment of Uncomplicated Urinary Tract Infections. Bristol Myers. 1985. (25% effort) 49. Yangco BG, Sinnott JT, Holder CD, Toney JF. A Multicenter Comparison of Intravenously Apalcillin and Piperacillin in Combination with Gentamicin in the Treatment of Hospitalized Patients with Fever and Granulocytopenia Secondary to Cancer Chemotherapy. Wyeth. 1985. (25% effort) 50. Yangco BG, Sinnott JT, Holder CD, Toney JF, Cullison JP. A Comparative Study of the Safety and Efficacy of Ceftazidime vs. Tobramycin/ Piperacillin in the Treatment of Hospital-Acquired Bacterial Pneumonia. Glaxo. 1985. (20% effort) 51. Nadler JP, Toney JF, Holt DA, Villanueva LP. A Study to Compare the Efficacy and Safety of 256U87 vs. Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients. Burroughs-Wellcome. 1995. (20% effort) 52. Nadler JP, Toney JF, Holt DA, Villanueva LP. A Comparative Trail of 256U87 and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV Infected Patients. Burroughs-Wellcome. 1995. (20% effort) John F. Toney, MD Page 15 53. Lyman G, Hiemenz J, Greene JN, Sinnott JT, Zuckerman KS, Toney JF, Dinwoodie W, Schapira D, Spiers ASD, Williams C, Hiemenz S, Ruckdeschel J, Horton J, Balducci L, DiConti RC. Phase III, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Leucomax (rhGM-CSF) when Administered to patients with Neutropenia and Fever Following Cytotoxic Chemotherapy for Non-Hematological Malignancies. Sandoz. 1995. (5% effort) 54. Bergen GA, Toney JF, Davis M. A Three arm comparative Trial for the Treatment of Mycobacterium avium - complex (MAC) Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen containing either Rifabutin 450 mg vs. Rifabutin 300 mg vs. Placebo. Adria. 1994. (30% effort) 55. Yangco BG, Craig CP, Sinnott JT, Holder CD, Toney JF. Multicenter Randomized, Blinded Study Comparing the Parental Therapy of Cefpiramide and Ceftizoxime in the Treatment of Hospitalized Patients with Infections Caused by Susceptible Aerobic and Anaerobic Bacteria. Wyeth. 1985. (20% effort) 56. Yangco BG, Craig CP, Sinnott JT, Holder CD, Toney JF. A Multicenter Open Study of the Efficacy, Safety, and Tolerance of Primaxin in the Parenteral Therapy of Presumed or Proven Bacterial Infection. Merck, Sharpe, and Dohme. 1985. (20% effort) 57. Yangco BG, Craig CP, Sinnott JT, Holder CD, Toney JF. Cefpimizole vs. Cefoperazone in Lower Respiratory Tract Infection. Upjohn. 1985. (20% effort) 58. Sinnott JT, Yangco BG, Craig CP, Holder CD, Toney JF. Cefoperazone in the Treatment of Bone and Joint Infections of Bacterial Etiology. Roerig. 1985. (10% effort) 59. Yangco BG, Sinnott JT, Craig CP, Holder CD, Toney JF. Early Phase II Efficacy and Safety of Teicoplanin in Patients with Gram Positive Infections. Merrell Dow. 1985. (20% effort) 60. Holder CD, Craig CP, Yangco BG, Sinnott JT, Toney JF. Emergency Treatment of Pneumocystis carinii Pneumonia in Immunoincompetent Patients with Difluoromethylornithine. Merrell Dow. 1985. (30% effort) 61. Yangco BG, Sinnott JT, Holder CD, Toney JF. An Open, Randomized Multicenter Evaluation of Ceftazidime Sodium Carbonate and Ceftazidime L-Arginine in the Treatment of Bacterial Infections of the Skin and Skin Structures and Blood in Adolescent and Adult Patients. Glaxo. 1984. (20% effort) 62. Yangco BG, Craig CP, Sinnott JT, Holder CD, Toney JF. Multicenter Phase II Open Non-Comparative Trial of Cefbuperazone in Infections of the Respiratory Tract and Skin and Skin Structure. Bristol. 1984. (20% effort) Current Grant Support 1. Toney JF, Gompf SG, Oehler RA. Efficacy, Immunogenicity, and Safety Study of Clostridium difficile Toxoid Vaccine in Subjects at Risk for C. difficile Infection. Sanofi Pasteur. 2014-present. (90% effort). SERVICE: Committees National Member - Safety Monitoring Committee NIH Division of Microbiology and Infectious Diseases (DMID) Protocol #13-0069 “Phase 1 Open Label Trial of the Safety, Tolerability, and Genitourinary and Pharyngeal Pharmacokinetics of Solithromycin” Sponsor: NIH. Site PI: Jonathan Zenilman, MD, Chief of the Infectious Diseases Division at the Johns Hopkins Bayview Medical Center, Johns Hopkins University (2015-current) Member - Evaluation Committee National Network of STD/HIV Prevention Training Centers Division of STD Prevention (DSTDP) Centers for Disease Control and Prevention (CDC) (2000-2011) Member - Marketing Committee National Network of STD/HIV Prevention Training Centers Division of STD Prevention (DSTDP) Centers for Disease Control and Prevention (CDC) (2000-2011) John F. Toney, MD Page 16 Member - Steering Committee National Network of STD/HIV Prevention Training Centers Division of STD Prevention (DSTDP) Centers for Disease Control and Prevention (CDC) (2000-2011) Co-chair - Steering Committee National Network of STD/HIV Prevention Training Centers Division of STD Prevention (DSTDP) Centers for Disease Control and Prevention (CDC) (2000-2003) Member - Strategic Planning Consultants Meeting (Chair, Cervical Cancer Workgroup), Division of STD/HIV Prevention, Centers for Disease Control and Prevention (CDC) (1994) State Member - Medical Advisory Committee on HIV/AIDS, Suncoast AIDS Network, State of Florida (1996 1997) Member - Medical Education Subcommittee on HIV and AIDS, Suncoast AIDS Network, State of Florida (1996 - 1997) Member - Pharmaceutical Advisory Subcommittee on HIV and AIDS, Suncoast AIDS Network, State of Florida (1996 - 1997) Member - AIDS Advisory Group, Department of Health and Rehabilitative Services (HRS), State of Florida, (1994 - 1998) Member - Hillsborough/Manasota Sexually Transmitted Disease Task Force, Department of Health and Rehabilitative Services, State of Florida (1988-1990) University Senator - Faculty Senate, University of South Florida (1995 - 1998) College of Medicine Treasurer – Faculty Counsel, Morsani College of Medicine, University of South Florida (2006 - 2010) Member - Clinical Research Committee, University of South Florida, Tampa, Florida (1994 - 1997) Department Member - Residency Recruitment Committee, Department of Internal Medicine, University of South Florida, (1987 - 1992) Hospital Member - Water Safety Committee, Veteran Integrated Service Network (VISN) 8, Tampa, Florida (2014present) Chair - Antimicrobial Stewardship Advisory Committee, James A. Haley VA Hospital, Tampa, Florida (2014present) Chair - Infection and Environmental Control Committee, James A. Haley VA Hospital, Tampa, Florida (1986 - present) Member - Patient Safety Committee , James A. Haley VA Hospital,Tampa, Florida (2010-present) Member - Reusable Medical Equipment Committee, James A. Haley VA Hospital, Tampa, Florida (2011present) Member - Department of Medicine Clinical Research Committee, James A. Haley VA Hospital, Tampa, Florida (2005-2007) Member - VISN 8 Pharmacy and Therapeutics Committee, Infectious Diseases Liaison, Veterans’ Integrated Service Network (VISN), Department of Veterans’ Affairs (1996 – 1999) Member - AIDS Management Board, James A. Haley VA Hospital, Tampa, Florida (1989 - 1999) John F. Toney, MD Page 17 Member - Pharmacy and Therapeutics Committee, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida (1990 - 1999) Member - Pharmacy and Therapeutics Executive Committee, James A. Haley VA Hospital, Tampa, Florida (1992 - 1999) Chair - Infection Control Committee, Vencor Hospital, Tampa, FL (1995 - 1998) Chair - Pharmacy and Therapeutics Committee, Vencor Hospital, Tampa, FL (1995 - 1998) Member - Therapeutic Agents Review Subcommittee,James A. Haley VA Hospital, Tampa, Florida (1991 1997) Chair - Biohazard Safety Committee, James A. Haley VA Hospital, Tampa, Florida (1991 - 1997) Member - Quality Assurance Committee, James A. Haley VA Hospital, Tampa, Florida (1986 - 1995) Member - Infection Control Committee, Tampa General Hospital, Tampa, Florida (1986 - 1990) Member - Discharge Planning Committee, James A. Haley VA Hospital, Tampa, Florida (1987 - 1990) Member - Medical District Initiated Peer Review, Organization (MEDIPRO) - Physician Advisor, James A. Haley VA Hospital, Tampa, Florida (1987 - 1989) Member - Institutional Review Board, Tampa General Hospital, Tampa, Florida (1988 - 1989) Chair - Subcommittee on Organ/Tissue Donation and HIV Disease, James A. Haley VA Hospital, Tampa, Florida (1987 - 1988) Community Service and Education: Interview – “Shingles – More Than a Bad Rash” August 11, 2015 VA VISN 8 Patient Health and Safety publication – access at http://www.tampa.va.gov/TAMPA/features/Shingles_a_Pain_in_the_Rash.asp Interview – “Shingles vaccine is pricey, but could be a wise investment.” Tampa Bay Times (online at http://www.tampabay.com/news/health/shingles-vaccine-is-pricey-but-could-be-a-wise-investment/218053) July 14, 2014. ABC News online article “Shingles – A Pain in the Rash” May 18, 2007 (located at http://abcnews.go.com/Health/ActiveAging/story?id=3185189&page=1) Public Service Announcements on Syphilis (South Florida area), Genital Herpes, and Antibiotic Resistance (statewide) - 2003 and 2004 Interview – The Race Against Resistance Creates Urgency for the Development of New Antimicrobials. Infection Control Today, 12/2003 (also available at www.infectioncontroltoday.com). Article - AIDS Therapy. Tampa Tribune, Tampa, Florida, 1994. Article - AIDS. St. Petersburg Times, Tampa, Florida, 1991. Article - Chronic Fatigue Syndrome. Tampa Tribune, Tampa, Florida, 1988 Membership in Professional and Scientific Societies Sigma Xi Scientific Research Society 2005 – 2014 American College of Physicians 1987 - present Infectious Diseases Society of America 1989 - present Florida Infectious Diseases Society (President, Vice President, Treasurer) 1993 - 2014 American Assoc. for the Advancement of Science 1987 - 1996 American Medical Association 1979 - 1994 American Society of Microbiology 1987 – 1994 John F. Toney, MD Page 18 Editorial Positions: Section Editor – “STD Bulletin” Infections in Medicine 1999-2003 Ad Hoc Reviewer Federal Practitioner – 2014 to present Clinical and Vaccine Immunology - 2007 Sexually Transmitted Diseases - 2005 Clinical Infectious Diseases 1998-2004 Infections in Medicine 1998-2009 Federal Practitioner 1997-2006 Cancer Control 1997-2000 Hospital Practice 1998 Journal of the American Podiatric Medical Association 1993 Western Journal of Medicine 1992