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Electron Transport Chain
NADH, FADH2 .have pair of electrons.
Electrons Transport from NADH, FADH2 .
to a series of electron carries in the form of
cytochroms to the ultimate acceptor O2 molecule and
produce H2O , so there are series of redox reaction.
Respiratory assemblies located in the
innermitochondrial membrane Oxidation &ATP
synthesis are coupled when proton influx to the
mitochondrial matrix.
1
2
NADH &FADH2 have
pair of electron (High
Energy Electron) .
These high energy
electron transferred
from mitochondrial
matrix to the electron
carriers in the form
of the cytochromes
embed within
mitochondrial
membrane
3
These high energy electrons
pass through a series of a
redox reactions
4
When the electrons pass
through a series of
cytochromes ,protons
pumps out side the
mitochondrial matrix .
At the end of this journey the
electron reach to the
ultimate electron acceptor
O2 molecule ,so O2 capture
pair of electron & form H2O
molecule.
5
In this slide water molecule
is formed as a process of
oxidation of proton by
oxygen molecule ,
oxidation & ATP synthesis
are coupled by
transmembrane influx of
proton inside
mitochindrial matrix .
6
The H+ ion is influs inside
mitochondrial matrih by
passing through the ATP
synthase this enzyme is
located with in inner
mitichondrial membrane
& these protons have high
energy & lead to the
Oxidative phosphorylation
of the ADP & formation
ATP or libration of
energy,formation of water
re-generation of
FAD,NAD
7
The presence of high
concentration of protons
out side the matrix lead to
High concentration gradients
relative to the matrix these
create a proton –motive
force due to two factors:
1- Decrease the PH
2- These protons have a high
energy so,these are
differences in electrical
potential &PH between
matrix &intermembrane
space
8
These difference in electrical
potential is sufficient to
synthesis ATP..
Synthesis of ATP is by the
difference in oxidation
&reduction potential
Of NADH & O2
Oxidation& synthesis of
ATP are coupled by influx
of proton into
mitochondrial matrix.
O2 react only at the last
stage , O2 is the ultimate
acceptor.
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