Download The Molecular Taxonomy of Cancer

THE MOLECULAR TAXONOMY OF CANCER
The 2004 CNIO Symposium
Madrid, Spain
3-6 February 2004
FEBRUARY 3rd
TO TAKE PLACE AT THE CNIO – Calle Mélchor Fernández Almagro, 3, 28029 Madrid
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1800h – 1900h Registration and Group Tours of the CNIO
1900h – 2100h Welcome Address and Party
FEBRUARY 4th
SYMPOSIUM VENUE: Auditorium Hospital Clínico San Carlos, Pabellón San Carlos, Prof. Martín
Lagos, s/n, 28040 Madrid
Keynote Lecture:
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0830h – 0915h - Peter Goodfellow - Glaxo-SmithKline, UK
Converting Knowledge Into Treatments
Session I: The Cancer Genome
Session Sponsor: Agilent Technologies
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0915h-0955h - Bob Weinberg - Whitehead Institute MIT, Cambridge, USA
Genetic and Biological Rules Governing Human Cancer Cell Formation
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0955h-1035h - Mike Stratton - Wellcome Trust Sanger Institute, Cambridge, UK
Genome-Wide Searches for Somatic Mutations in Cancer
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1035h-1115h - Olli Kallioniemi - VTT Technical Research Centre of Finland, Turku, Finland
Integration of molecular, cellular and clinical biochip technologies in molecular oncology research
and therapy development
1115h – 1155h – Coffee/Poster Viewing and Sponsored Talk – Agilent Technologies
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1155h-1235h - Mary-Claire King - University of Washington, Seattle, Washington, USA
Genetic Analysis of Breast and Ovarian Cancer
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1235h-1315h - Manel Esteller – Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain
Cancer as an Epigenetic Disease: Unveiling DNA Methylation and Chromatin Alterations
Selected Oral Presentations
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1315h-1330h – Chris Boshoff – Cancer Research UK, London, UK
Gene Expression Microarrays reveal the Lymphatic Endothelial Lineage and Cytokine
Network of Kaposi Sarcoma
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1330h-1345h – Marta Sánchez Carbayo – Memorial Sloan-Kettering Cancer Center, NewYork, USA
1345h-1445h – Lunch Break
Session II: Profiles in Carcinogenesis
Session Sponsor: Affymetrix
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1445h-1525h - Louis Staudt - Center for Cancer Research, NIH, Bethesda, USA
Molecular Diagnosis and Molecular Targets in Lymphomas by Gene Expression Profiling
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1525h-1605h -Miguel A. Piris – Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain
Expression Profiling and Cancer Pathogenesis
Invited Short Talk
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1605h-1625h - Adolfo Ferrando – Dana Farber Cancer Institute, Boston, USA
Molecular Pathogenesis of T-Cell Leukemia: Defining Therapeutic Targets
1625h-1655h Coffee/Poster Viewing and Sponsored Talk by Affymetrix
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1655h-1735h - Laura Van´t Veer - The Netherlands Cancer Institute, Amsterdam, The Netherlands
Expression Profiling to Change Clinical Practice in Breast Cancer
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1735h-1815h - Todd R. Golub - HHMI/Dana Farber Cancer Institute, Boston, USA
Genomic Information and Cancer
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1815h-1855h - Emanuel Petricoin - Food and Drug Administration, Bethesda, USA
Clinical Proteomics: Patient Tailored Therapy and Early Detection of Human Malignancies
FEBRUARY 5th
Session III: Hallmarks of Cancer
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0900h-0940h - Gerard Evan - UCSF Comprehensive Cancer Center, San Francisco, USA
Determining the Requirements for Tumour Maintenance in vivo
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0940h-1020h - Karen Vousden - Beatson Institute for Cancer Research, Glasgow, UK
The p53 tumor suppressor as a target for tumor therapy
Selected Oral Presentations
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1020h-1035h - José Fernández Piqueras - Universidad Autónoma de Madrid, Spain
Defective expresión of Notch 1 and Notch 2 in connection to alterations of c-Myc and Ikaros
in y-radiation induced mouse thymic lymphomas
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1035h-1050h – Isabel López de Silanes – National Institute on Ageing, NIH, Baltimore, USA
Identification of HuR target mRNAs in colon cancer cells
1050h-1130h – Coffee/Poster Viewing and Technology Presentation, Qaigen
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1130h-1210h - James R. Downing - St. Jude Children´s Research Hospital, Memphis, USA
The Molecular Pathology of Acute Leukemia: A Genomic View
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1210h-1250h - Mariano Barbacid – Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain
Manipulating the Mouse Genome: A New Generation of Animal Tumour Models
Selected Oral Presentation
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1250h-1305h – Myriam Alcalay – FIRC Institute of Molecular Oncology, Milan, Italy
Acute Myeloid Leukemia fusion proteins deregulate genes involved in stem cell maintenance
and DNA Repair
Invited Short Talk
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1305h-1325h – Cathy Lofton Day – Epigenomics Inc., Seattle, USA
DNA Methylation profiling for the diagnosis of colorectal cancer
1325h-1435h - Lunch Break/Technology Presentation, Becton Dickinson
Session IV: Cancer in silico
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1435h-1515h - John Quackenbush - The Institute for Genomic Research, Rockville, USA
Using Expression Profiles to Classify Tumors and Discover Biology
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1515h – 1555h - Joaquín Dopazo – Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain
Using gene ontology on genome-scale studies to find significant associations of biologically
relevant terms to groups of genes
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1555h-1635h - Chris Sander - Memorial-Sloan Kettering Cancer Center, New York, USA
Computational Biology and Cancer Research
1635h-1720h – Coffee/Poster Viewing and Technology Presentation, Bruker
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1720h – 1800h -Colin Hill - Gene Network Sciences, Ithaca,USA
Determining Efficacy of Targets and Lead Compounds via a Data-Driven Computer
Simulation of Human Cancer Cells
Selected Oral Presentations
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1800h-1820h - Alfonso Valencia, Centro Nacional de Biotecnología (CNB), Madrid, Spain
Bioinformatics and Computational Biology in the study of protein interaction networks
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1820h-1840h – Jian-Bing Fan, Illumina Inc., San Diego, USA
Gene Expression Profiling in Formalin-Fixed, Paraffin-Embedded Tissues Using Universal
Bead Arrays
Evening Sponsored Talk and Aperitif – Amersham Europe
FEBRUARY 6th
Session V: Targets and Therapeutics
Session Sponsor: Roche Farma S.L.
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0900h-0940h - Nicholas C. Dracopoli - Bristol Myers Squibb, Princeton, USA
Pharmacogenomic Applications in Oncology Drug Development
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0940h-1020h - Josep Baselga - Hospital Vall d´Hebrón, Barcelona, Spain
Pharmacodynamic Endpoints and Patient Selection with Targeted Therapies
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1020-1100h - Carlos García-Echeverría– Novartis Institutes for Biomedical Research, Basel, Switzerland
Targeted Anticancer Drugs — Dream or Reality?
1100h-1145h – Coffee/Poster Viewing
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1145h-1225h - Greg Hannon - Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
RNAi: Mechanism, Biological Functions and Applications
Selected Oral Presentations
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1225h-1240h – Carlos Moreno – Emory University, Atlanta, USA
Loss of HOXC6 Expression Induces Apoptosis in Androgen-dependent and Androgenindependent Prostate Cancer Cells
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1240h-1255h – Peter Reigman – Erasmus MC, Rotterdam, The Netherlands
The European Human Frozen Tumour Tissue Bank (Tubafrost)
Closing Keynote
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1255h-1340h - Sir John Maddox, Editor Emeritus, Nature, UK
What lies ahead?
Concluding Remarks
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1340h-1350h – Miguel A. Piris – Centro Nacional de Investigaciones Oncológicas, Madrid, Spain