Download NIHbioKAM - Kurt A. Mossberg

Principal Investigator/Program Director (Last, First, Middle): Mossberg,
Kurt A.
BIOGRAPHICAL SKETCH
Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
POSITION TITLE
Mossberg, Kurt Alan
Professor
eRA COMMONS USER NAME
kmossber
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION
Illinois State University – Normal, IL
Texas Woman’s University – Houston, TX
U of Texas Health Sci Center – Houston, TX
Texas
Woman’s
University
– Houston,
TXTX
U of Texas
Health
Sci Center
– Houston,
U of Texas Health Sci Center– Houston, TX
U of Texas Health Sci. Center- Houston, TX
DEGREE
(if applicable)
YEAR(s)
FIELD OF STUDY
B.S.
M.S.
Ph.D.
Ph.D.
Post-doc
Post-doc
1975
1979
1979
1987
1987-1989
Biological Sciences
Physical Therapy
Physiology/Metabolism
Exercise/Glucose uptake
NOTE: The Biographical Sketch may not exceed four pages. Follow the formats and instructions on the
attached sample.
A. Positions and Honors. List in chronological order previous positions, concluding with your present position. List
any honors. Include present membership on any Federal Government public advisory committee.
Positions and Employment:
1979-1980
Staff Physical Therapist, St. Joseph’s Hospital, Houston, TX
1980-1981
Lecturer, Texas Woman's University, Houston, TX
1981-1984
Instructor, Texas Woman's University, Houston, TX
1986-1990
Assistant Professor, Texas Woman's University, Houston, TX
1990-1992
Research Assistant Professor, U of Texas Health Science Center, Houston, TX
1992-1995
Associate Professor, Physical Therapy, U of Texas Medical Branch, Galveston, TX
1995-2001
Associate Professor and Chair, Physical Therapy, U of Texas Medical Branch, Galveston, TX
2001-2007
Associate Professor, Physical Therapy, U of Texas Medical Branch, Galveston, TX
2007-present Professor, Physical Therapy, U of Texas Medical Branch, Galveston, TX
Honors:
1992
1993
1996
1997
2001
2002
2002
2005
2006
2006
2009
Research Award, Texas Physical Therapy Association Annual Conference
Outstanding Research, School of Allied Health Sciences, UTMB
Outstanding Research, School of Allied Health Sciences, UTMB
Grand Marshal, School of Allied Health Sciences Commencement, UTMB
Best Abstract and Presentation, Cardiovascular and Pulmonary Section, APTA (research)
Outstanding Professor Award, Department of Physical Therapy, UTMB
Researcher of the Year Award, Texas Physical Therapy Association
Outstanding Professor Award, Department of Physical Therapy, UTMB
Fannie Kempner Adoue Distinguished Professorship, UTMB
Grand Marshal, School of Allied Health Sciences Commencement, UTMB
Jack Walker Award for Outstanding Clinical Practice publication, APTA
B. Selected peer-reviewed publications (in chronological order). Do not include publications submitted or in
preparation.
Selected Peer Reviewed Publications:
Baruch IM, Mossberg KA: Heart rate response to nonweight bearing walker ambulation in 60-80 year old
women. Phys Ther 63:1782-1787, 1983.
PHS 398/2590 (Rev. 09/04)
Page
Biographical Sketch Format Page
Principal Investigator/Program Director (Last, First, Middle): Mossberg,
Kurt A.
Mossberg KA, Mullani N, Gould KL, Taegtmeyer H: Skeletal muscle blood flow in vivo: Detection with 82-Rb
and effects of glucose, insulin, and exercise. J Nucl Med 28:1155-1163, 1987.
Merhige ME, Ekas R, Mossberg K, Taegtmeyer H, Gould KL: Catecholamine stimulation, substrate
competition, and myocardial glucose uptake in conscious dogs assessed with positron emission
tomography. Circ Res 61 (Suppl II):II124-II129, 1987.
Mossberg KA, Rowe RW, Tewson TJ, Taegtmeyer H: Rabbit hindlimb glucose uptake assessed with positron
emitting 18-F-2-deoxy-2-fluoro-D-glucose. J Appl Physiol 67:1569-1577, 1989.
Mossberg KA, Linton KA, Friske K: Effect of ankle-foot orthoses on energy expenditure of gait in spastic
diplegic children. Arch Phys Med Rehabil 71:490-494, 1990.
Spence DW, Galantino MLA, Mossberg KA, Zimmerman SO: Progressive resistance exercise: Effect on
muscle function and anthropometry of a select AIDS population. Arch Phys Med Rehabil 71:644-648,
1990.
Nguyen VTB, Mossberg KA, Tewson TJ, Wong W-H, Rowe RW, Coleman GM, Taegtmeyer H: Temporal
analysis of myocardial glucose metabolism by 2-[18F]fluoro-2-deoxy-D-glucose. Am J Physiol 259:H10221031, 1990.
Mossberg KA, Taegtmeyer H: Dihydroergotamine as a pharmacologic euglycemic clamp in the surgically
traumatized rabbit. Metabolism 40:594-599, 1991.
Taegtmeyer H, Mossberg KA, Nguyen VTB: Positron labeled tracers: A window for the assessment of energy
metabolism in heart and skeletal muscle. Acta Radiol (Suppl) 376:40-44, 1991.
Mossberg KA, Taegtmeyer H: Effect of contractile activity on skeletal muscle glucose uptake. Analysis of
temporal responses. Acta Radiol (Suppl) 376:146-147, 1991.
Mossberg KA, Taegtmeyer H: Time course of glucose uptake during hyperinsulinemic euglycemic clamp: A 2deoxy-2-fluoro-D-glucose study. J Nucl Med 33:1523-1529, 1992.
Mossberg KA, Mommessin JI, Taegtmeyer H: Skeletal muscle glucose uptake during acute contractile activity
in vivo: Effect of prior contractions. Metabolism 42:1609-1616, 1993.
Peel C, Mossberg KA: Effects of cardiovascular medications on exercise responses. Phys Ther 75:387-396,
1995.
Mossberg K, McFarland C: Initial health status of clients at outpatient physical therapy clinics. Phys Ther
75:1043-1053, 1995.
Sykes M, Gouge D, Newstead A, Freeman G, Tomberlin JA, Mossberg K: The effects of therapeutic horseback
riding on balance in persons with brain injury. In Engel BT, ed. Rehabilitation with the Aid of a Horse: A
Collection of Studies. Madison, WI: Omnipress; 1997. pp. 127-135
Baker CP, Newstead AH, Mossberg KA, Nicodemus CL: Reliability of static standing balance in nondisabled
children: comparison of two methods of measurement. Pediatric Rehabil 2:15-20, 1998.
Mossberg K, Willman C, Topor MA, Crook H, Patak S: Comparison of asynchronous versus synchronous arm
crank ergometry. Spinal Cord 37:569-574, 1999.
Mossberg K, McFarland C: Patient oriented health status after out-patient physical therapy. Am J Phys Med
Rehabil 80:896-902, 2001.
Mossberg KA, Peel C: Beta-adrenergic antagonists. In Bahrke MS, Yesalis CE, ed. Performance-Enhancing
Substances in Sport and Exercise. Champaign, IL: Human Kinetics; 2002. Chapter 14, pp. 149-156
Mossberg KA, Kuna S, Masel B: Ambulatory efficiency in persons with acquired brain injury after a
rehabilitation intervention. Brain Injury 16:789-797, 2002. {erratum appears in Brain Injury 17(3):266, 2003}
Mossberg KA: Reliability of a six-minute walk test to assess aerobic fitness in persons with acquired brain
injury. Am J Phys Med Rehabil 82:385-390, 2003.
Mossberg KA, Greene BP: Reliability of a graded exercise test after traumatic brain injury: submaximal and
peak responses. Am J Phys Med Rehabil 84:492-500, 2005.
Mossberg KA, Ayala D, Baker T, Heard J, Masel B: Aerobic capacity after traumatic brain injury: Comparison
to a non-disabled cohort. Arch Phys Med Rehabil 88:315-320, 2007.
Mossberg KA, Orlander EE, Norcross JL: Cardiorespiratory capacity after supported treadmill training in
patients with traumatic brain injury. Phys Ther 88:77-87, 2008.
Mossberg KA, Gilkison C, Masel B, Urban R: Aerobic capacity and growth hormone deficiency after traumatic
brain injury. J Clin Endocrinol Metab 93:2581-2587, 2008.
PHS 398/2590 (Rev. 09/04)
Page
Biographical Sketch Format Page
Principal Investigator/Program Director (Last, First, Middle): Mossberg,
Kurt A.
Baker CP, Rosenberg M, Mossberg KA, Holzer C, Blakeney P, Robert R, Thomas C, Meyer W: Relationships
between the Quality of Life Questionnaire (QLQ) and the SF-36 among young adults burned as children.
Burns 34:1163-1168, 2008
Beca SG, High WH, Masel BE, Mossberg, KA, Urban RJ: What are critical outcome measures for patients
receiving pituitary replacement following brain injury? Pituitary. EPub Jul 2, 2008.
Bhagia V, Gilkison C, Fitts RH, Zgaljardic DJ, High WH, Masel BE, Urban RJ, Mossberg KA: Effect of
recombinant growth hormone replacement in a growth hormone deficient subject recovering from mild
traumatic brain injury: A case report. Brain Injury 24(3):560-567, 2010
Mossberg KA, Masel BE: Endurance training and improved aerobic capacity after traumatic brain injury. In
Van Der Woude LHV, Hoekstra F, De Groot S, K. E. Bijker KE, R. Dekker R, Van Aanholt PCT, Hettinga
FJ, Janssen TWJ, and Houdijk JHP, eds. Rehabilitation: Mobility, Exercise and Sports - 4th International
State-of-the-art Congress. Amsterdam, NL: IOS Press; 2010, pp276-278
Mossberg KA, Amonette WE, Masel BE: Endurance training and cardiorespiratory conditioning after traumatic
brain injury. Journal of Head Trauma Rehabilitation. In press.
Selected Peer Reviewed Published Abstracts (not published in full):
Mossberg KA: Reliability of a maximal treadmill wheelchair propulsion test. Phys Ther 74(Suppl):S80, 1994.
Mossberg KA: Exercise as a provocative test for assessing the glucose transport system in diabetic muscle.
Phys Ther 74(Suppl):S78, 1994.
Mossberg KA: Reliability of a peak arm crank ergometry test in individuals with spinal cord injury. World
Confederation for Physical Therapy: Congress Proceedings:684, June 1995.
Mossberg KA: Effects of arm crank ergometry on wheelchair propulsion in individuals with spinal cord injury.
Phys Ther 76:S69, 1996.
Rogers H, Mossberg K: Standard vs. lightweight wheelchairs: a comparison of metabolic efficiency in treadmill
propulsion. Phys Ther 80:S45, 2000.
Baker C, Mossberg KA, Meyer WJ, Brown J, Ehlig A, Spencer H: Perceived health status of young adults
burned as children. J Burn Care Rehabil 23(2):S155, 2002.
Mossberg KA, Champa J, Edwards P, Puentes V: Reliability of the SF-36 in individuals with acquired brain
injury. American Physical Therapy Association, 2003. At:
http://www.ptjournal.org/abstracts/pt2003/abstractsPt2003.cfm?pubNo=PO-RR-39-F.
Mossberg K, Masel B, Urban R: Effect of growth hormone supplementation on cardiorespiratory fitness after
traumatic brain injury. Archives of Physical Medicine and Rehabilitation. 86:e12-e13, 2005. Available at:
http://linkinghub.elsevier.com/retrieve/pii/s0003999305010464
Mossberg K, Norcross J, Orlander E, Fisher S: Validity and responsiveness of the six-minute walk test in
individuals with traumatic brain injury. American Physical Therapy Association, 2006. Available at:
http://www.ptjournal.org/abstracts/pt2006/abstractsPt.cfm?pubNo=PO-RR-73-F
Mossberg K, Norcross J, Orlander E: SF-36 vs. clinical measures of endurance capacity. J Head Trauma
Rehabil. 21:416, 2006.
Ronsen O, Symons B, Børsheim E, Mossberg K, Wolfe R: Test-retest of time to exhaustion in traumatic brain
injury patients. American College of Sports Medicine, 2006. Available at:
http://www.abstractsonline.com/viewer
Fitts RH, Romatowski JG, Peters JR, Gilkison C, Mossberg KA, Sheffield-Moore M, Urban RJ. Effect of rhGH
replacement in persons with moderate to severe traumatic brain injury (TBI) on single muscle fiber function.
Endocrine Society, June 2007. Available at: http://www.abstracts2view.com/endo
High WM, Mossberg KA, Briones-Galang M, Gilkison C, Masel BE, Urban RJ. Effect of rhGH Replacement in
Persons with Moderate to Severe Traumatic Brain Injury (TBI) on Neuropsychological Test Performance,
Aerobic Capacity, Body Composition and Community Integration Questionnaire (CIQ). Endocrine Society,
June 2007. Available at: http://www.abstracts2view.com/endo
Mossberg K, DeGray B, Riitho I, Thomas A: Relationship between heart rate and oxygen consumption after
traumatic brain injury. American Physical Therapy Association, June 2008.
Mossberg K, Temple R, Masel B: Effects of acute aerobic exercise on neurocognition after traumatic brain
injury. Journal of Head Trauma Rehabilitation. 24(5), 399-400, 2009.
PHS 398/2590 (Rev. 09/04)
Page
Biographical Sketch Format Page
Principal Investigator/Program Director (Last, First, Middle): Mossberg,
Kurt A.
Amonette WE, Mossberg K: Anaerobic thresholds of patients after traumatic brain injury: Comparison to
healthy sedentary controls. Combined Sections Meeting, APTA, Feb 2010. Available at: http://aptacsm2010.abstractcentral.com/planner?NEXT_PAGE=ITINERARY_ABS_DET_POP&ABSTRACT_ID=6566
11&SESSION_ABSTRACT_ID=550440&SESSION_ID=57292&PROGRAM_ID=2519
C. Research Support. List selected ongoing or completed (during the last three years) research projects (federal and
non-federal support). Begin with the projects that are most relevant to the research proposed in this application.
Briefly indicate the overall goals of the projects and your role (e.g. PI, Co-Investigator, Consultant) in the research
project. Do not list award amounts or percent effort in projects.
MOSSBERG, K.A.
ONGOING
#R01 HD046570-01, National Institutes of Health; Physical work capacity after traumatic brain injury, 200611. The primary goal of this project is to examine the effectiveness of body-weight supported treadmill
training in persons recovering from traumatic brain injury (TBI). The project’s aims are to examine
changes in both physical and cognitive function. Mossberg has complete oversight on this project as
Principal Investigator.
The Moody Endowment; Amino acid supplementation in recovery after brain injury. Elisabet Børsheim, PI;
2007-09 (no cost extension 2010-2011). This is a pilot project with the goal of assessing the feasibility
of long-term amino acid supplementation in persons recovering from traumatic brain injury (TBI). The
project’s aims are to examine changes in both physical and cognitive function. Mossberg has complete
responsibility for all physical function evaluations as Co-Investigator.
Moody Foundation; Growth hormone replacement after mild traumatic brain injury. Co-Investigator, 10% inkind effort; Randall Urban, PI; 2009-11. this is a pilot project assessing the effects of recombinant
growth hormone replacement in patient with TBI who are found to be deficient (hypopituitarism).
Mossberg has complete responsibility for all physical functioning evaluations as Co-Investigator.
PENDING
COMPLETED
#2005-07, Moody Endowment; Improving physical and psychological health in individuals with brain injury
and the frail elderly, 2005-06. The goal of this project was to explore the changes in physical and
cognitive function as a result of high intensity physical training in patients recovering from TBI. In
addition, the project included the examination of a program to improve self-efficacy of the frail elderly.
Mossberg had complete oversight for the project as Principal Investigator.
The Moody Foundation; Anterior pituitary hormone replacement in closed head injury, Randall Urban, PI;
2004-06 (no cost extension, 2006-07). The primary goal of this project was to examine the
effectiveness of growth hormone replacement in patients recovering from TBI who are growth hormone
deficient. Mossberg had complete oversight of measures of physical function with an emphasis on
aerobic capacity testing as Co-Investigator.
#2004-03, Moody Foundation; Improving movement efficiency in individuals with acquired brain injury, 200405. The goal of this project was to explore the changes in aerobic capacity as a result of body weight
supported treadmill training in a post acute residential rehabilitation center for patients recovering from
TBI. Mossberg had complete oversight for the project as Principal Investigator.
PHS 398/2590 (Rev. 09/04)
Page
Biographical Sketch Format Page