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2015 DEPARTMENT OF MEDICINE RESEARCH DAY Title of Poster: A Population-Based Analysis of Oral Cavity Cancer in 55,775 Patients Presenter: Jose Alonso, MSIII Division: Head & Neck Surgery ☐Faculty ☐Fellow ☐Resident ☐Post-doc Research Fellow ☐Graduate Student ☒Medical Student ☐Other Principal Investigator/Mentor: Maie St. John MD Co-Investigators: John W. Frederick MD Thematic Poster Category: Clinical Observations and Clinical Trials Outcomes and Objectives: The goals of this review were to characterize trends in the treatment of oral cavity cancer over time and to compare outcomes across large patient populations. Methods: The population-based Surveillance, Epidemiology, and End Results (SEER) cancer registry was utilized to identify all patients between 1972-2011 diagnosed with oral cavity malignancy. A retrospective cohort analysis of this group was compiled and specific demographic data, treatment modalities, and survival outcomes were recorded. Differences in outcomes based on treatment modality, year of diagnosis, and demographic factors were evaluated using Kaplan-Meier methods and multivariate analysis. Results: We identified a total of 55,775 patients diagnosed with oral cavity malignancy. The majority of patients (59%) were male and most patients fell between the ages of 41-79 (80%). Treatment groups included surgery, radiation, or a combination of surgery and radiation. The most common treatment modality was surgery alone (53%), while 26% of patients received a combination of surgery and radiation or were treated with radiation (20%). There was a significant difference in treatment modality used depending on patient race. Trends in modality used overtime were consistent. Improved survival was seen in patients receiving surgery alone and depended on race and year of diagnosis. Conclusion: Patient factors are associated with the treatment and survival of oral cavity cancer and these factors should be considered in the treatment of the disease.