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CHEM&131- INTRO TO ORGANIC/BIOCHEMISTRY
Spring 2017
LECTURE
LAB section 3044
LAB section 3046
Room RAI 361
Room RAI 206
Room RAI 206
10:00 – 10:50 am
1:00-2:50 pm
3:00 – 4:50 pm
PIERCE COLLEGE
M-F
M
M
INSTRUCTOR
Email
Phone
Office Hours
Amy Satterlee
[email protected]
253-912-2399 ext.5543
1:00-3:00
Room RAI 217
TEXT
Not Required-Use as a resource for additional practice problems
Introduction to Organic and Biochemistry (CHEM& 131-Pierce College Custom 3rd
Edition)
Chapters 11-24 of Book: General, Organic & biological Chem, Janice Smith
PREREQUISITES
CHEM&121
Tues, Thurs & Fri
COURSE DESCRIPTION
Chemistry 131 surveys organic and biochemistry. It is designed to follow 121, a survey of inorganic
chemistry. These two courses together are particularly appropriate for students hoping to enter allied
health professions such as dental hygiene and nursing. The course covers nomenclature and structure of
the major classes of organic compounds including alkanes, alkenes, alcohols, ethers, esters, amines, and
carboxylic acids. It also covers biochemically important compounds such as carbohydrates, proteins,
enzymes, and nucleic acids. Finally, the role of these compounds in metabolic pathways and DNA
replication is examined. We will follow these Course Objectives:
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
Recognize, name and draw the structures of the main organic functional groups.
Name selected organic molecules using International Union of Pure & Applied Chemistry (IUPAC) based on
condensed or structural formulas.
Draw structural or condensed formulas from IUPAC names.
Describe the hybridization of carbon in organic molecules.
Relate physical properties to molar mass, polarity and functional group.
Relate the reactions of functional groups to metabolic pathways.
Identify and explain the reactions that form carbohydrates, lipids, proteins and nucleic acids.
Describe and draw: structural isomers, geometric isomers, stereoisomers.
Differentiate glycosidic linkages, anomerism, metabolic value, and optical rotation between different classes of
carbohydrates.
Classify lipids and discuss their physiological importance.
Relate saponification, hydrolysis and esterification to lipids.
Describe the role of lipids in cell membranes.
Classify amino acids based on their chemical structure.
Relate the structure of polypeptides to the amino acids it contains and to peptide bonds.
Describe the interactions between amino acids as they relate to primary, secondary, tertiary and quaternary
protein structures and how these are affected by denaturation.
Relate isoelectric point of amino acids to charge, electrophoresis, and zwitterions.
Correlate enzyme activity to the reactions of functional groups.
Describe the models of enzyme activity.
Discuss how enzyme activity is affected by pH, temperature, substrate concentration, and enzyme
concentration.
Differentiate between aerobic and anaerobic metabolism.
Explain the relationship between glycolysis, the Krebs cycle, and the fatty acid spiral.
Describe Adenosine Triphosphate (ATP) production.
Describe the structure and function of DNA and RNA, and relate them to replication, transcription and
translation.
Explain protein synthesis and the impact of mutations on protein synthesis.
Design and carry out experiments.
Use standard laboratory equipment appropriately.
27. Practice standard laboratory safety precautions.
28. Use chemical reference materials appropriately.
29. Communicate the results of laboratory work.
ATTENDANCE
Good attendance with a positive attitude will improve your chances of success. If you are absent, it is
your responsibility to get notes, assignments, and keep up with syllabus schedule and announcements of
changes from classmates/canvas.
TARDINESS
If you are late to an exam, you will receive an automatic 10% point reduction. If you are late to the final
exam, you will receive a 20% point reduction. No penalty will be applied to tardiness for lecture sessions,
however if you miss the quiz, there will not be a makeup provided to you. Tardiness during lab-if prelab
discussion is missed, will result in an automatic zero for the lab and you will not be allowed to participate
in that days lab. If you have a medical excuse (providing a doctors note), all of these rules may be
adjusted by the instructor.
STUDY
Our class time each week is limited and, therefore, we need to make the best possible use of it. You will
be expected to come prepared. On a daily basis plan to review the class notes, complete homework
assignments, and go through practice worksheets online for extra help or see the SI.
HELP
The best time to ask questions is at the moment when you are having difficulty. Don’t let questions pile up
or you may become completely lost. Please don’t hesitate to ask me for additional help if you need it!
Tutoring is also available (Drop-In or Peer Tutors) through The Tutoring Center (CAS Room 526). Please take
advantage of this program. You also will have an SI for this course so take advantage of this program.
Tutoring Center Cascade 526 www.pierce.ctc.edu/go/tutoring (253) 964-6737
HOMEWORK
Homework problems will be assigned for each unit section covered. Homework will be due at the
beginning of the class period assigned in the syllabus (see schedule). Please work through each problem
carefully and completely: always show all steps and clearly indicate your answers. Also, label each
assignment with the problem numbers clearly visible. I will be scanning the work for completion, so if the
assignments are out of order or are not easily identified, no credit will be given.
EXTRA CREDIT
Extra credit opportunities will be available to be turned in on the date of the unit exam. Each extra credit
is worth 1 point that will be added to your unit exam grade (not to exceed 100%). No extra credit will be
offered on the final exam.
QUIZZES
We will have several quizzes throughout the quarter. See the syllabus schedule for when these will be
given.
LABS
We will have weekly 2 hour lab experiments. It is your responsibility to prepare ahead of time by reading
the entire lab exercise carefully. During the experiment, you will be required to record all data and
observations in the lab manual. Lab work and the lab reports will be done in pairs. The reports will be due
the following lab period. The lowest lab report grade will be dropped at the end of the quarter. More
details about all of this and lab safety will be given in class. No lab make-ups. Manual will be provided to
you. If you miss 3 labs during the quarter you will receive an automatic 0.0 for the course.
EXAMS
There will be an exam for every unit covered (average 3 chapters). There will be four total (worth 100
points each). There will also be a comprehensive final exam that covers the material from your 4 exams.
Make-ups will be given only in medical situations where a note can be provided and if advance notice is
given.
LATE WORK AND MAKE-UP WORK
Students are expected to turn in all assignments, at the beginning of class on the announced due date,
unless, prior to that time, instructor permission has been granted to turn in the material late. Assignments
turned in after this time, are considered late. Late work will be assessed a 20% loss of credit for being late.
Assignments will not be accepted after the corresponding unit exam (Ex: ALL unit 1 work will not be
accepted after completion of the unit 1 exam). NO LATE WORK WILL BE ACCEPTED AFTER YOU HAVE
SUBMITTED YOUR FINAL EXAM.
Make-Up Exams: Exams and quizzes may not be taken late except under circumstances that are preapproved by the instructor. If an emergency situation results in an absence, you must contact the
instructor on or before the exam date or as soon as possible. The validity of the emergency absence is
subject to the instructor’s discretion and a makeup exam might not be allowed. Medical excuses or
preapproved excuses get 1 week to make up missed work. Nonmedical excuses get 2 days to make up
missed work at a 20% reduction; nonmedical excuses still must be approved by the instructor and is up to
the discretion of the instructor as to whether a make-up will be allowed.
WITHDRAW POLICY
You may withdraw from this class, and it will not show up on your transcript. If you wish to withdraw after
the withdraw date, you will need instructor permission. Please talk with me if you believe there may be a
reason for you to withdraw.
GRADING
Your final grade for the course will be calculated as the percentage of the total possible points that you
have earned. The graded components of the class are as follows:
ITEM
POINTS EACH
POINTS TOTAL
7 Quizzes
10
70
12 Homework Assignments
Metabolism WS/
metabolism participation
Review 121 WS (lab)
8 Lab Reports (9-drop
lowest)
4 Unit Exams
10
120
15
15
15
15
20
160
100
400
Final Exam
200
200
Total points
----
980
The following grade scale will be used:
A
100
99
98
97
96
95
94
93
92
91
90
B
4.0
4.0
4.0
4.0
4.0
4.0
3.9
3.8
3.7
3.6
3.5
89
88
87
86
85
84
83
82
81
80
C
3.4
3.3
3.2
3.1
3.0
2.9
2.8
2.7
2.6
2.5
79
78
77
76
75
74
73
72
71
70
69
68
67
66
65
D
2.4
2.4
2.3
2.3
2.2
2.2
2.1
2.1
2.0
2.0
1.9
1.8
1.7
1.6
1.5
64
63
62
61
60
59
58
57
56
55
54
53
52
51
50
1.4
1.4
1.4
1.3
1.3
1.3
1.2
1.2
1.2
1.1
1.1
1.1
1.0
1.0
1.0
SPECIAL NEEDS
Please notify me within the first week of class if you are in need of special accommodations due to a
disability so that proper arrangements can be made quickly.
DISABILITY ACCOMODATION STATEMENT:
Fort Steilacoom and Military sites: Students with disabilities who believe they may need academic
adjustments, auxiliary aids or services to fully participate in course activities or meet course requirements
are encouraged to register with the Access and Disability Services (ADS) Office, Room 300K in the
Cascade Building. You may also call the ADS Office at (253) 964-6526 or 964-6460 to make an
appointment. Students requesting accommodations must obtain the “Approved Quarterly Academic
Adjustments, Auxiliary Aids or Services” (green) form provided by ADS.
ACADEMIC DISHONESTY
Cheating or the appearance of cheating will not be tolerated. If you are caught cheating on a quiz or
test, you receive zero points for that assignment. If you are caught cheating a second time, you receive
a failing grade for the course. Please refer to your student handbook for the college policy.
Tentative Course Schedule (subject to change)
Refer to the Canvas Announcements for changes to the course schedule
If a section is completed early, we will move on the next section so be prepared
Date
Week 1 Apr 03
Lecture
Syllabus & Intro
Textbook
Apr 04
Apr 05
Apr 06
Apr 07
Week 2 Apr 10
Unit 1-1
Unit 1-1
Unit 1-1
Unit 1-1
Unit 1-1
Chapter 11/ 12
Quiz 1 & Unit 1-2
Unit 1-2
Unit 1-2
Instructor Absence
Chapter 13
Apr 11
Apr 12
Apr 13
Apr 14
Week 3 Apr 17
Apr 18
Apr 19
Instructor Absence
from lecture only
Unit 1-2
Quiz 2 & Unit 1-3
Apr 20
Apr 21
Unit 1-3
Unit 1-3
Week 4 Apr 24
HW
Lab 1-Structural Isomers
Unit 1-1 HW
(due April 11)
Unit 1-2 HW
(due April 19)
Lab 2-Properties of
Hydrocarbons
Chapter 14
Unit 1-3 HW
(due April 24)
Exam 1(Unit 1)
Lab 3- Preparation of
alkene
Apr 25
Apr 26
Unit 2-1
Unit 2-1
Chapter 16
Apr 27
Apr 28
Week 5 May 01
Quiz 3 & Unit 2-2
Unit 2-2
Unit 2-2
Chapter 17
May 02
Unit 2-2
May 03
May 04
May 05
Week 6 May 08
Quiz 4 & Unit 2-3
Unit 2-3
NO CLASS-In Service
Unit 2-3
May 09
May 10
May 11
Exam 2 (Unit 2)
Unit 3-1
Unit 3-1
May 12
Week 7 May 15
R/S Quiz 5
Unit 3-2
Lab (Thursdays)
Lab Safety & Check-In
Review 121 Worksheet
Unit 2-1 HW
(due April 27)
Lab 4-synthesis of
aspirin
Unit 2-2 HW
(Due May 03)
Chapter 17/18
Lab 5-Vitamin C
*lab handout provided
in lab
Unit 2-3 HW
(due May 09)
Chapter 15
Unit 3-1 HW
(Due May 15)
Chapter 20
Lab 6- optical isomers
*Bring notes on R/S
May 16
May 17
Unit 3-2
Unit 3-2
May 18
May 19
Week 8 May 22
May 23
Quiz 6 & Unit 3-3
Unit 3-3
Unit 3-3
Unit 3-3
May 24
May 25
May 26
Week 9 May 29
May 30
Exam 3 (Unit 3)
Unit 4-1
Unit 4-1
NO CLASS-Holiday
Unit 4-1
May 31
June 01
Quiz 7 & Unit 4-2
Unit 4-2
Chapter 21
Unit 4-3
Unit 4-3
Chapter 22
June 02
Week 10 June
05
June 06
June 07
June 08
June 9
Week 11 June
12
June 13
June 14
June 15
June 16
Unit 3-2 HW
(Due May 18)
Chapter 19
Lab 7- carbohydrates
Unit 3-3 HW
(Due May 24)
Chapter 21
No Class-Holiday
Unit 4-1 HW
(Due May 31)
Unit 4-2 HW
(Due at June 02)
Lab 8-Separation of
Amino Acids
*lab handout provided
in lab
Unit 4-3
Exam 4 (Unit 4)
Metabolism WS
Metabolism WS
Metabolism WS
Unit 4-3 HW
(Due June 07)
Chapter 23/24
Lab 9- Catalase
Review for Final
------------Comprehensive final Finals are scheduled for June 14-16
Look on Pierce College homepage under the “Resources” tab for “Finals Schedule”
Final-Wed June 14 10-12:00