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Development of organs – general embriology Elongation of the blastocyst Lamina neuralis (with blue) and the sulcus neuralis. On both sides of sulcus neuralis somites start to develop. Primitive streak and primitive node (stria primitiva, nodus primitivus) 1 Types of placenta ca: zonaria, endotheliochorial eq: diffuse, epitheliochorial su: diffuse, epitheliochorial ru: cotyledonaria (multiplex), synepitheliochorial ho: discoidea, hemochorial Fetal cotyledon + maternal caruncula = placentome 2 3 Early differentiation of mesoderm and closure of neural folds Bending of the embryo and formation of somites Single mesoderm and chorda dorsalis Paraxial mesoderm and lateral plate mesoderm Separation of lateral plate mesoderm Intermedier mesoderm (in the middle), somatopleura (next to ectoderm), and splanchnopleura (next to entoderm). Differentiation of entoderm, early entodermal structures 4 Latero-lateral folding of the embryo Colors: - blue: ectoderm - red: mesoderm - yellow: entoderm Cranio-caudal folding of the embryo Videos about folding: - https://www.youtube.com/watch?v=qMnpxP6EeIY - http://www.indiana.edu/~anat550/genanim/latfold/latfold.swf 5 Development of body cavities Common thoracic and abdominal cavity canalis pleuroperitonealis The entodermal-derived lungs gradually grow into the thoracic cavity Adhesion of plica pleuropericardiales /n. phrenicus (with black) and v. cardinalis communis (with pink) are embedded into to fold/ Formation of diaphragm: septum transversum (ventrally, orange), pleuroperitoneal folds (from both sides, blue), mesenterium dorsale (in the midline), and mesodermal-derived muscle-cell ingrowth (circularly,6 red)