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MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
Course Code: 200031001
TOPIC XXI: MOLECULAR GENETICS - DNA and Replication
Pacing
Date
Traditional 4 days
Block
ESSENTIAL CONTENT
A. Experiments and History**
1. Bacterial Transformation (16.12)
2. Experiments: (Griffith, Hershey & Chase)
2 days
03-16-16 to 03-30-16
03-16-16 to 03-30-16
INSTRUCTIONAL TOOLS
 Summarize the experiments that lead to the discovery of Core Text Book: Ch. 12 all sections
DNA as the genetic material, its structure, location in the
Vocabulary:
cell, and function. **
 Explain that the basic components of DNA are universal DNA, Nucleotide, RNA, Messenger RNA, Double helix,
B. Universal code for all organisms (16.9)
Base pairing, Nitrogenous base, Hydrogen bonding,
in organisms.
1. Role of DNA
Replication, DNA polymerase, Transcription, RNA
 Recall that the basic components of DNA are
2. Similarities evidence of ancestry
Polymerase, Transformation, Mutation, Mitosis, Meiosis,
universal in organisms and that similarities in the
Thymine, Adenine, Guanine, Cytosine, RNA splicing,
genetic codes of organisms are due to common
C. Review of Structure of DNA and location in the cell**
Gamete, Codon, Template
ancestry. (ALD)
1. Components of DNA
 Explain how similarities in the genetic codes of
2. Double helix
organisms are due to common ancestry and the process Technology:
3. Location in cell and importance
1. HHMI: Building Blocks of DNA
of inheritance.
4. Genes
2. HHMI: DNA replication animation
 Identify the nitrogen base pairs found in DNA and
3. Art in Motion: DNA and genetic material
summarize its structure.
D. Role of Nucleic acids in organisms (18.1)
 Identify and describe the primary function of nucleic 4. Interactive Art: DNA Replication
1. Primary function
5. Art in Motion: Hershey Chase Experiment
acids in organisms. (ALD)
2. Molecular structure
 Explain the basic processes of DNA replication and/or its 6. Tutor Tube: Memory Tricks for Base Pairing
7. Bozeman Podcast: DNA & RNA Part 1
role in the transmission and conservation of genetic
E. DNA Replication in Cell Cycle (16.3, 16.17)
8. Bozeman Podcast: DNA & RNA Part 2
information.
1. DNA template
9. Bozeman Podcast: DNA Replication
 Differentiate the cellular processes of DNA
2. Cell cycle (S Phase); Mitosis, Meiosis, and Mutations
10. Bozeman Podcast: What is DNA?
replication, transcription, and/or translation. (ALD)
3. Location of process (nucleus)
11. Khan Academy: DNA
 Explain how gene and chromosomal mutations may or
12. Edgenuity
may not result in a phenotypic change.
F. Types of Mutations and effects
13. Packet 21 DNA Replication L.16.3
 State that mutations that affect the proteins that
1. Effects on offspring (16.4)
regulate the cell cycle my result in uncontrolled cell
2. Effects on individual: Cancer (16.8)
growth. (ALD)
Division of Academics – Department of Science
Third Nine Weeks
OBJECTIVES
Page 1 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
Course Code: 200031001
SC.912.L.16.3
Building DNA
SC.912.L.16.3
DNA Fingerprint Analysis

Video
Standard:
SC.912.L.16.3
Image
Article
Standard:
SC.912.L.16.4
Video
Standard:
SC.912.L.16.8
Video

James Watson and Francis Crick:
DNA Molecule Has the Form of a
Double Helix
Rosalind Franklin and Maurice
Wilkins: X-Ray Crystallography of
DNA
DNA: Deoxyribonucleic Acid
DNA double helix
Cell with chromosomes and genes
highlighted
Direction of transcription



Franklin, Rosalind Elsie
Polymerase Chain Reaction
RNA







Chromatin, Chromosomes, and DNA 
Subunits

Genes
The Importance of DNA


Nucleic Acids
Messenger RNA: Transcribing the
Message
The Central Dogma: DNA Replication
The Central Dogma: RNA and
Transcription

 The Role of DNA in Genetic Variation
Between and Among Species


Gene Mutation Research
Free Radicals and Genetic Mutations

Division of Academics – Department of Science
Third Nine Weeks
Page 2 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
Standard:
SC.912.L.16.9
Course Code: 200031001
Video
Video
Standard:
SC.912.L.18.1
Audio
Video
Standard:
HE.912.C.1.7
Audio
Division of Academics – Department of Science
Third Nine Weeks
 Introduction to the Genetic Code
 The Language of Life
 The Genetic Code
 Video Quiz: Part One
 Molecules, Compounds, and
Macromolecules
 Macromolecules
 Carbohydrates
 Lipids: Fats and Oils
 Lipids & Cholesterol
 The Structure of the Cell: Proteins and
Enzymes








 Hunting Down the Genes Involved in
Disease
 DNA and the Genetics of Cancer
 Genetic Disease
 Families and Genetic Disease
 Genetic Case Study: Addison's Disease
 Cystic Fibrosis
 Diabetes
The Role of Genes
Mendel's Laws of Inheritance
Inheritance Patterns
Heredity: How Our Parents' Genes
Affect Us
 Basic Facts About Cancer
 Obesity
Proteins
An Introduction to Proteins
Proteins and Amino Acids
Protein Shapes Revisited
 What Is Protein?
 Structures and Functions of Different
Proteins in the Body
 Nucleic Acids




Risk Factors for Heart Disease
DNA Screening
High & Low Risks for Cancer
High & Low Risks for Cardiovascular
Disease
 High & Low Risks for Diabetes
 Is Tone Deafness Hereditary?
 Can Your Grandfather's Diet Shorten
Your Life?
Page 3 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
Course Code: 200031001
Video
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




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DNA Evidence Links Albert DeSalvo to Boston Strangler Murders
Supreme Court Rules DNA Samples Allowed in Arrests for Serious Crimes
DNA Evidence: Powerful Tool or Privacy Violation?
Richard III Found in a Parking Lot
Researchers: "Junk DNA" Plays Critical Role
Tomato: DECODED
Convictions Based on Hair Analysis Under Review
Researchers Map DNA of Fetus from Blood and Saliva of Parents
DNA Testing Connects Unlikely Cousins
DNA Testing: How Accurate Is It? And How Is It Done?
Division of Academics – Department of Science
Third Nine Weeks
Page 4 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Learning Goals
BIOLOGY I
Course Code: 200031001
SC.912.L16.3: Describe the basic process of DNA replication and how it relates to the transmission and conservation of the genetic information. ( Cognitive Complexity: Level 3:
Strategic Thinking & Complex Reasoning)
SC.912.L16.5: Explain the basic processes of transcription and translation and how they result in the expression of genes. ( Cognitive Complexity: Level 3: Strategic Thinking &
Complex Reasoning )
SCALE
LEARNING PROGRESSION

I am able to distinguish among the cellular processes of DNA replication,
transcription, and translation.
Using a given DNA nucleotide sequence, trace the pathway
from replication to transcription and translation.
Identify the corresponding protein sequence that will form
based on the original DNA nucleotide sequence and what
could occur if the original DNA sequence was changed in
any way.
Score/Step 5.0

I am able to differentiate the cellular processes of DNA replication, transcription,
and translation.
Create a diagram demonstrating the processes of DNA
replication, transcription and translation. Include
descriptions of each process and how they differ from one
another.

I am able to differentiate the cellular processes of DNA replication, transcription,
and translation.
Given a diagram of the processes of DNA replication,
transcription and translation, identify the correct sequence
of each process.

I am able to choose the correct cellular process of DNA replication.
Given a diagram of the components of DNA replication,
identify the correct sequence of replication.

I am able to understand that every organism has hereditary information stored in
DNA that get passed on from one generation to another.
Score/Step 4.0
Score/Step 3.0 Target
(Learning Goal)
Score/Step 2.0
Score/Step 1.0
SAMPLE PROGRESS MONITORING AND ASSESSMENT
ACTIVITIES
Division of Academics – Department of Science
Third Nine Weeks
Page 5 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Learning Goals
BIOLOGY I
Course Code: 200031001
SC.912.L16.8: Explain the relationship between mutation, cell cycle, and uncontrolled cell growth potentially resulting in cancer. (Cognitive Complexity: Level 2: Basic
Application of Skills & Concepts)
SCALE
LEARNING PROGRESSION
SAMPLE PROGRESS MONITORING AND ASSESSMENT
ACTIVITIES

I am able to assess how uncontrolled cell growth may result from mutations that
affect the proteins that regulate the cell cycle.
Describe how to prevent cancer by preventing mutations.

I am able to assess how uncontrolled cell growth may result from mutations that
affect the proteins that regulate the cell cycle.
Given a scenario of a patient just diagnosed with cancer,
trace the history of those cancer cells back to when they
were healthy.

I am able to state that mutations that affect the proteins that regulate the cell cycle
may result in uncontrolled cell growth.
Sequence the events that result in uncontrolled cell growth:
certain proteins regulate checkpoints in the cell cycle so
that it proceeds normally, a mutation occurs in the DNA of a
gene of one of these proteins, the wrong protein is made,
the checkpoint is no longer properly regulated, cells divided
without control.

I am able to recall that uncontrolled cell growth may result in cancer.
Given two difference sequences that show normal cell
division and uncontrolled cell division, describe the end
result of each sequence.

I am able to recall that cells divide in order to make more cells.
Score/Step 5.0
Score/Step 4.0
Score/Step 3.0 Target
(Learning Goal)
Score/Step 2.0
Score/Step 1.0
Division of Academics – Department of Science
Third Nine Weeks
Page 6 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Learning Goals
BIOLOGY I
Course Code: 200031001
SC.912.L.18.1: Describe the basic molecular structures and primary functions of the four major categories of biological macromolecules. ( Cognitive Complexity: Level 2: Basic
Application of Skills & Concepts )
SCALE
LEARNING PROGRESSION
SAMPLE PROGRESS MONITORING AND ASSESSMENT
ACTIVITIES

I am able to summarize the basic molecular structure and the primary function of
macromolecules in organisms.
Develop an argument for each macromolecule and justify
their level of importance in various organisms.

I am able to summarize the basic molecular structure and the primary function of
macromolecules in organisms.
Construct models of each of the four macromolecules and a
Venn diagram that compares and contrasts the molecules
based on elemental composition, structure, function.

I am able to identify the basic molecular structure and the primary function of
macromolecules in organisms.
Create a foldable that names the four macromolecules,
describes two major functions of each, and identifies the
basic molecular structure.

I am able to identify the primary function of the four macromolecules in organisms.
Match each macromolecule to a brief description of the
various functions.

I am able to recognize that there are four macromolecules.
Score/Step 5.0
Score/Step 4.0
Score/Step 3.0 Target
(Learning Goal)
Score/Step 2.0
Score/Step 1.0
Division of Academics – Department of Science
Third Nine Weeks
Page 7 of 7