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St. Michael-Albertville High School CIS Human Biology (Master) Teacher: Kay Nowell September 2014 Content CEQ Skills 1. Describe the process of gastrulation and the resulting arrangement How does a single undifferentiated cell lead of the embyro's organs. to a complex multicellular organism? 2. Explain how the onedimensional information in DNA is How does the body used to direct the three maintain homeostasis? dimensional form of an How have technological embryo. advances helped in the 3. Explain how nuclear fight against disease? transplantation can be used to clone animals What effect does 4. Describe some of the culture, politics and practical applications of economics have on our reproductive cloning ability to fight disease? 5. Describe the process and goals of therapeutic cloning 6. Distinguish between Embryonic Development and Stem opposing viewpoints of the use of stem cells Cells and explain the basis for UEQ those viewpoints How does information from DNA result in the formation of an embryo? Learning Targets I can describe how the process of gastrulation produces a three layered embryo which forms the organ systems. I can explain how genes regulate and coordinate development. I can compare and contrast the current stem cell technologies and recognize the ethical implications. Assessment Stem Cell Activities Resources & Technology Campbell Biology Concepts and Connections 7th Edition; Reece, Taylor, Simon and Dickey Copyright 2012 Notes: Do the stem Pearson Chapter 27.9-27.12 Reproduction cell science first... Life before birth video and Embryonic Development and Ch. also show lifes greatest 11.12-11.15 miracle because it shows gastrulation 29 The Science and Ethics of Stem Cell Research: The Northwest Association of min. in... Biomedical Research www.nwabr.org NW association for biomed research lesson 1.1 modeling Howard Hughes Medical Institute Holiday stem cell development. Lectures on Science: Potent Biology Stem text 27.9-27.12 Cells, Cloning and Regeneration didn't use Stem Cell basics pkt. Articles: skipping Stem cell pluripotency, new basics http://stemcells.nih.gov.info/ student ways to make esc, race pkt to grow new organs, growing livers in Biotech Power point lymph nodes. Show Body builders 9 min. DVD/Video Library: Body BuildersGrowing body organs 9min, Life's Greatest Make sure that you Miracle (NOVA), Stem Cell encorporate new Research:Independent Lens, Life before developments into the birth unit on the stem cell basics packet to avoid confusion to what can and cannot be done. www.curriculummapper.com 1 of 8 CIS Human Biology (Master) Nowell Content Skills What are the differences between adult, fetal and embryonic stem cells? Explain the differences between reproductive technologies and describe their medical potentials How do ethical considerations determine which therapies will be pursued? Learning Targets St. Michael-Albertville High School Assessment Resources & Technology Unit Test Stem cell ethics section Science and Ethics of stem cell research activites, Independent Lens video When does life begin conception quiz rewrite the Principles of Embryonic development and include learning targets on the handout below the key points. October 2014 Content Gene Expression and DNA Technologies What is the cellular basis of reproduction and inheritance? How are genes controlled? Skills 1. Explain how gene expression is controlled 2. Explain the significance of the epigenome in terms of environmental changes to the genome and lifestyle choices. 3. Distinguish between the genome and the proteome Learning Targets I can explain the role of regulatory genes in the expression of the DNA. Assessment Fruit Fly experiments did not do, may consider. Unit Test I can describe the significance of the epigenome and how lifestyle choices can alter the expression of genes. Epigenetics activity Resources & Technology Campbell Biology Concepts and Connections 7th Edition; Reece, Taylor, Simon and Dickey Copyright 2012 Pearson Chapter 11 How Genes are Controlled and Chapter 12 DNA Technology and Genomics National Institute of Health Curriculum Supplement: Human www.curriculummapper.com 2 of 8 CIS Human Biology (Master) Nowell Content What is the genetic basis of cancer and how can lifestyle choices reduce the risk? How can DNA technologies be used to improve lives? How do cells age? Skills 4. Explain how viruses, proto-oncogenes, and tumor-suppressor genes can each contribute to cancer. 5. Describe how telomere length dictates a cell’s life span. 6. Analyze the benefits and risks of emerging DNA technologies Learning Targets I can explain how genes regulatory genes are involved in the development of cancer. I can analyze the benefits and risks associated with emerging DNA technologies. St. Michael-Albertville High School Assessment Resources & Technology Genetic Variation Howard Hughes Medical Institute Holiday Lectures on Science: Genomics and Chemical Genetics and The Double Life of RNA HHMI Gene Regulation Guide, HHMI Gene Expression Guide, HHMI Biotechnology Guide Ghost in your Genes epigentics Video and resources NOVA DVD: Genes (Sci. Am Frontiers) Guest Speaker on Genetic Cancer link http://learn.genetics.utah.edu... / http://www.time.com/time/magaz... http://www.sciencemag.org/site... http://epigenome.eu/en/1,1,0 November 2014 www.curriculummapper.com 3 of 8 Nowell Content Immune System and Disease UEQ How do infectious agents cause disease? What is innate immunity? How does the adaptive immune response counter specific invaders? How can malfunction or failure of the immune system cause disease? CIS Human Biology (Master) Skills 1. Explain the nature of innate defenses 2. Identify the steps of the inflammatory response and how they help to prevent the spread of disease 3. Describe the structure and functions of the lymphatic system 4. Describe the adaptive immune response 5. Define and distinguish between the humoral and cell mediated immune responses 6. Explain how cytotoxic T cells destroy infected body cells 7. Explain why it has been difficult to develop a successful treatment for AIDS 8. Explain how the body distinguishes self from non-self and how this system complicates organ transplantations 9. Describe how the malfunction or failure of the immune system can cause disease. Learning Targets I can describe the role of the lymphatic system in fighting disease. I can differentiate between the first, second and third line of defense. I can explain how the body distinguishes cell from non-self and how infectious organisms and cancer are able to elude the defense system. St. Michael-Albertville High School Assessment Unit Test Immune system Immune system activities and assignments Infectious Disease Project Resources & Technology Campbell Biology Concepts and Connections 7th Edition; Reece, Taylor, Simon and Dickey Copyright 2012 Pearson Chapter 24 Immune System and Disease National Institute of Health Curriculum Supplement: Evolution and Medicine, Confronting the Microbe Menace. AIDS Evolution of an Epidemic HHMI Immunology Guide, The National Center for Case Study Teaching in Science http://sciencecases.lib.buffalo.edu Northwest Association for Biomedical Research: HIV Vaccine Research The Pathophysiology of the Human Immunodeficiency Virus: HIV Curriculum for the Health Professional RX for Survival Disease Warriors DVD and Curriculum Video/DVD Library: AIDS in Africa, Age of AIDS (Frontline), The Link Between Environmental www.curriculummapper.com 4 of 8 CIS Human Biology (Master) Nowell Content Skills Learning Targets St. Michael-Albertville High School Assessment Resources & Technology Change and Infectious Disease (Journey to Planet Earth), Race Against the Super Flu, Microkillers Ebola, Influenza 1918 Epidemic, Black Death (not bubonic plague???), Unnatural Causes, Anatomy of a pandemic, Killer Disease on Campus (Meningitis), Vaccines (Frontline), Parasites, Secrets of the Dead Black Death, Ebola Plague Fighters (NOVA), Killer Flu, H5N1 Flu (Primetime), December 2014 Content Endocrine System UEQ 1. How do hormones affect cells? 2. How are the nervous and the endocrine systems connected? 3. What are the implications of hormone imbalances on the body systems? 4. How do hormone levels change over the course of a lifetime? Skills Compare and contrast the mechanisms and functions of the endocrine and nervous system 2. Distinguish between the signaling mechanisms of amino-acidderived hormones and steroid hormones 3. Describe the Learning Targets Assessment Unit Test Professor hauslein retired. New advisor and will need to revamp course to match the college Completion of Case Study 1. Resources & Technology Campbell Biology Concepts and Connections 7th Edition; Reece, Taylor, Simon and Dickey Copyright 2012 Pearson Chapter 26: Hormones and Endocrine System: DVD/Video Library: Doping for Gold, Science of the Sexes, Is it a Boy or Girl?, Steroids. The National Center for Case Study Teaching in Science http://sciencecases.lib.buffalo.edu www.curriculummapper.com 5 of 8 CIS Human Biology (Master) Nowell Content Aging, Diabetes, Depression, Sleep, Gonads and Sex Hormones, Metabolism, Environmental Hormone Disruptors,Stress and the Adrenal Gland Skills Learning Targets St. Michael-Albertville High School Assessment Resources & Technology interrelationships between the hypothalamus and the pituitary glands 4. Explain the role of hormones in: aging, diabetes, depression, sleep, metabolism, stress and aging January 2015 Nervous System Content UEQ How do neurons receive and process inputs and communicate responses How do neurotransmitters function at the synapse How do drugs act at chemical synapses and how can this lead to addiction? What are the roles of the sympathetic and parasympathetic divisions of the nervous system? Skills 1. Describe the structure and function of the subdivisions of the nervous system 2. Describe the structure and functions of neurons and the myelin sheath 3. Explain how an action potential is produced, propagated and returned to resting potential 4. Compare and contrast types and functions of neurotransmitters 5. Explain how drugs can alter chemical synapses Learning Targets We did not get to this unit. I will be redesigning the curriculum with Professor Hauslein from SCSU this summer and will add targets if we keep this unit in the curriculum. Hauslein retired. will rewrite to allign with SCSU Assessment Resources & Technology Unit Test Nervous system Campbell Biology Concepts and Connections 7th Edition; Reece, Nervous system activities Taylor, Simon and Dickey Copyright 2012 Pearson Chapter and assignments 28 Nervous Systems Reaction Paper National Institute of Health Curriculum Supplement: Neurological Condition Understanding Neurobiology Project Through the Study of Addiction Comprehensive Final Howard Hughes Medical Institute Project: Scientific Poster Holiday Lectures on Science: Presentation at SCSU Cancer/Neuroscience: Learning Research Colloquim. Assessment and resources from Patients the science of medicine. Making Your Mind: will vary depending on www.curriculummapper.com 6 of 8 CIS Human Biology (Master) Nowell Content How does the limbic system coordinate emotions, memory and learning? How can changes in brain physiology result in neurological disorders? Skills Learning Targets 6. Compare the functions of the motor and autonomic nervous systems 7. Compare the structures, functions and interrelationships of the parasympathetic, sympathetic and enteric divisions of the peripheral nervous system. 8. Describe the main parts and functions of the human brain. Detail the structures and functions of the cerebral cortex 9. Explain how the brain regulates sleep and arousal 10. Describe the structure and functions of the limbic system and relate it to how memories are stored. 11. Describe the causes, symptoms and treatments of schizophrenia, depression, Alzheimer’s and Parkinson’s disease St. Michael-Albertville High School Assessment Resources & Technology topic, time of year, current molecules, motion and memory events, etc... The National Center for Case Sheep brain dissection Study Teaching in Science http://sciencecases.lib.buffalo.edu DVD library:Football high (head injuries), Blow to the Brain (60 minutes program 13 min), Stress portrait of a killer, Worried Sick (Sci. Am. Frontiers), Placebo Effect (Sci. Am Frontiers), Concussions and Female Athletes, How Does the Brain Work (Nova Science Now), Savants Accidental Genius, Chess Champions-Brain Wiring, Parkinson's (Frontline), Inside the Teenage Brain (Frontline), Don't Forget -Alzheimer's (Sci. Am Frontiers), Alzheimer's, Awakenings February 2015 Research Colloquim at St. Cloud State Content Skills Learning Targets Assessment Resources & Technology www.curriculummapper.com 7 of 8 Nowell Content EQ will be determined by the instructor at SCSU. The topic changes every year. CIS Human Biology (Master) Skills Compile research from primary sources to investigate an issue in human biology. Create a scientific poster that will be used to convey information on the selected topic to an audience at research Colloquium. Learning Targets I can compile current primary research sources to develop a scientific poster to convey the complexity of an issue to an audience at the Research Colloquium. St. Michael-Albertville High School Assessment Comprehensive Final Project: Scientific Poster Presentation at SCSU Research Colloquium. Assessment and resources will vary depending on topic, time of year, current events, etc... Resources & Technology Internet resources Guest Instructor Present the poster and explain in further the poster. www.curriculummapper.com 8 of 8