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Thyroid:Symptomsandwhattheymeantoyou
ByDRVIVIENLIMCHINCHIN
SPECIALISTINENDOCRINOLOGY(GLANDSANDHORMONES)
Oneinninepatientsmaysufferfromathyroiddisorderandoverhalfofthemmightnotbeawareof
this.Thethyroidisaglandthatresidesbelowthevoicebox(wheretheAdam’sappleisinthemales)
intheneck.
Themajorthyroidproblemsare:
-
Toomuchthyroidhormone–knownashyperthyroidism
Toolittlethyroidhormones–knownashypothyrioidism
Toobigathyroidgland–knownasagoitre
Cancer
Toomuchthyroidhormones-hyperthyroidism
Symptoms:
-
feelstoohot
losingweightevenwithincreasedappetite
shakingofhands
fastheartrateorfeelingasenseofheartbeatingveryfastinthechest
bulgingeyes
menstrualirregularities
hairloss
diarrhoea
anxious,restless,fidgety
Causes:
-
mostlikelysecondarytoantibodiesagainstthethyroidglandcausingittoproducemore
hormones
lesslikely–thyroidnodulethatisactive,glandwithmanynodulesthatareactive,acentral
pituitarycausethatisproducingcommandhormonesthattellthethyroidglandtoproduce
morethyroidhormones
Treatment:
-
medication–inmostcountriesthisistheinitialtreatmentegmethimazole,carbimazoleor
propylthiouracil
radioactiveiodine
surgery–usuallythisisamethodoflastresortunlessthethyroidglandistoobigandis
obstructingtheairwayorforcosmeticreasons
Toolittlethyroidhormones–hypothyrioidism
Symptoms:
-
slowingdown
weightgain
coldintolerance
constipation
feelingtired
menstrualirregularities
hairloss
Causes
-
Vastmajorityduetothyroidantibodiesthatdestroythethyroidglandhenceleadingtoa
decreaseinproductionofthyroidhormones
Treatment
-
Appropriatereplacementofthethyroidhormone
Bigthyroid–goitre
Causes:
-
Bothhyper-andhypo-thyroidismcanbeassociatedwithabigthyroid
Anodule(lump)ormultiplenodulesinthethyroid
Rarelycancer
Treatment:
-
-
-
Firsttobeabletovisualisethethyroidglandusinganultrasound.Andtoseeifthereareany
nodules.Ifthereare,toascertainwhethertheyarecancerousornot–onewayisbythe
ultrasoundcharacteristicsandtheotherbydoingabiopsyofthethyroidnodule–thisis
knownasfineneedleaspirationcytology.Asmallneedle(smallerthanthatofaneedleused
totakebloodfrompatients)isinsertedintothethyroidnoduleandcellsobtainedfor
visualisationunderthemicroscope.
Ifthenodulesarenotcancerous–optionsofmanagementarediscussedandwillincludethe
following:
o Continuewithmonitorregularlywithultrasound
o Removalofthelobewhichthenoduleisin
Ifthenoduleiscancerous–seebelow.
Thyroidcancer
Thisisusuallyslowgrowingandmightpresentasanodule.Fortreatmentofnodulesseeabove.If
cancerisproven,managementisassuch:
-
Removalofthewholeofthethyroidgland
Decisionmadeastowhetherradioactiveiodineisneeded–thisisusuallydoneforthyroid
cancerswithhigherriskofrecurrence
Suppressivetherapy–ietosuppressthecommandhormonesforthethyroidglandthatcan
alsostimulatecancercells.Thisisusuallydonebygivingthyroidhormonereplacementsata
higherdosethannormal.