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Blood Mr. Wilson 7th Grade pre-ap Instructions 1. 2. 3. 4. You will need at least one sheet of paper to complete # 2-4. Go through the PowerPoint and complete any task or questions. Take notes from the power point that you think would be helpful to help answer questions about the topic. Write down two things you learned and 1 question you have. Blood • Objectives: • Identify the parts and functions of blood • Explain why blood types are checked before a transfusion • Give examples of diseases of blood • Section Notes: • Blood plays a part in every major activity of your body. Blood Facts Functions of blood • Blood has four important functions • Blood carries oxygen from your lungs to all your body cells. Carbon dioxide diffuses from your body cells into your blood. Your blood carries carbon dioxide to your lungs to be exhaled. • Blood carries waste products from your cells to your kidneys to be removed • Blood transports nutrients and other substances to your body cells. • Cells and molecules in blood fight infections and help heal wounds. Parts of Blood • What % of your body weight is blood? Blood Clotting • You cut your finger while helping your mom cut up vegetables. Already the wound area has begun to heal. Bleedings stops because platelets and clotting factors in your blood make a blood clot that plugs the wounded blood vessels. • A blood clot also acts somewhat like a bandage. When you cut yourself, platelets stick to the wound and release chemicals. • Chemical reactions form a threadlike fibers that form a sticky net. The clot helps more blood from escaping. • After the clot becomes hard skin cells begin to repair under the scab, with the scab finally falling off. Bacteria that gets into the wound during the healing process usually are destroyed by white blood cells. Clotting factor • There are 13 proteins that make up the coagulation factor. The picture shows thirteen proteins that make up the clotting factor. • Most people will not bleed to death from a minor wound such as a cut or scrape. However, some people have a genetic condition called hemophilia which we will talk about in a few slides. Blood types • People are born with one of hour types of blood: A, B, AB, O. • Types A, B, and AB have chemical identification tags called antigens on their red blood cells. Type O red blood cells have no antigens. • Each blood type also has specific antibodies in the plasma. Because of these antibodies certain blood types cannot mix. This limits blood transfusion possibilities. • Rh factor also plays a role in whether a transfusion takes place or not. It is simply either Rh- or Rh+. Blood Transfusions • In 1665 the first successful blood transfusion was performed between two dogs. The first successful human to human blood transfusion was performed in 1818. However many failures followed. The different blood types and the problems that result when they are mixed were unknown at that time. • Research the discovery of the four types of blood? Transfusion Diseases of Blood • Anemia • Body tissue can’t get enough oxygen and are unable to carry on their usual activities. • Usually caused by lack of iron, lack of certain vitamins, or a major blood loss. • Sickle-cell disease • People with sickle-cell disease have misshapened red blood cells. The sickle-shaped cells clog the capillaries of a person with the disease. Oxygen cannot reach tissues served by the capillaries and wastes cannot be removed. • Leukemia • Is a disease in which one or more types of white blood cells are made in excessive numbers. These cells are immature and do not fight infection well. These immature cells fill the bone marrow and crowd out of the normal mature cells. • Hemophilia • Peoples plasma lacks on of the clotting factors that begins the clotting process. A minor injury can be a life threatening problem for a person with hemophilia. Summary • Blood carries oxygen, carbon dioxide, wastes and nutrients. • Blood contains cells that help fight infections and heal wounds. • Blood is a tissue made of plasma, red and white blood cells and platelets. • Platelets and clotting factors form blood clots to stop bleeding from a wound • Blood type-A, B, AB, or O-must be identified before a person receives a transfusion • Anemia affects red blood cells , while leukemia affects white blood cells.