Download Gelyma - Integrity Ingredients Corporation

ADVANCED MARINE ACTIVE AGENTS
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Founded by experts in Marine Biology, GELYMA cultivates independence and passion for Phycology.
Thanks to its in-depth algal scientific know-how, always looking for new sourcing and applications,
GELYMA creates, develops, manufactures and sells innovative ingredients prepared from microalgae
and seaweeds collected throughout the world.
Its distribution network serves about 30 countries in Europe, North America and Asia.
Unique range of 26 active ingredients with effective solutions
China
2015
Trade names
Benefits
Doses
SKIN AGEING – ANTI-WRINKLING
for reducing the appearance of fine lines & wrinkles and improving firmness
Unique synergistic combination of algal growth substances
ACTISEANE
Marine growth substances : not similar to phyto-oestrogens
PATENTED
1% - 4%
Reinforces skin metabolism
Keeps vitality to mature skin
Complementary properties
• anti-UVB, anti-elastase and anti-hyaluronidase activities
• modulation of cytokine balance: IL-6 stimulation & IL-1α
inhibition
INCI names: water (and) Ascophyllum nodosum extract (and) Halopteris
scoparia extract
DERMOCEA
China
2015
Innovative association of innovative red seaweeds
for a plumper and firmer skin
0.5% - 2%
Wards off skin ageing
Restructures the cutaneous framework
• epidermal restructuring activity for reinforcing skin integrity
increase of Keratin K 14 expression
• reduction of saggy skins by enhancing skin moisture,
restoring skin volume and increasing skin firmness
activation of the synthesis of GAGs, collagens I & III
inhibition of MMP-1 activity
inhibition of hyaluronidase activity
INCI names: water (and) sucrose (and) Meristotheca dakarensis extract
(and) Jania rubens extract
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Targets adaptive defensive stress response through
hormesis based- prevention
FIRM’ACT
Up-regulates the gene expression of unique markers involved in
the adaptive cellular stress response for maximizing protective
effects (MT-1, MT-2 , HSPA1A , NQO1 genes)
3% -5%
Strengthens the dermal structure for boosting ECM
Maintenance
• stimulation of fibroblast proliferation
• stimulation Type I collagen synthesis
• stimulation hyaluronic acid synthesis
Clinical studies:
China
2015
Increases skin antioxidant capacity & protects skin against UVDamage (skin lipo peroxidation)
Delays facial skin sagging
Increases skin firmness & elasticity
INCI names: water (and) Himanthalia elongata extract (and) Fucus
vesiculosus extract (and) Saccharomyces cerevisiae extract.
The anti-ageing power behind Green caviar / Sea grape
OKINACEA
1% - 5%
Improves skin functional integrity by reinforcing the DEJ
• activation of Type IV collagen and laminin-5 synthesis
Ameliorates skin firmness by reinforcing the dermal structure
• increase of GAGs and Type I collagen synthesis
Clinical studies:
Reduces skin roughness - anti-wrinkle activity
INCI names: water (and) Caulerpa lentillifera extract (and) Hydrolyzed
Rice Bran protein
Age-defying strategy
TONIKELP
1% - 3%
Saves your skin from premature ageing
• stimulation of HAS-2 enzyme that produces hyaluronic acid
• increase of Type III collagen synthesis
• improvement of syndecan 4 synthesis
• protection against oxidative stress (mitochondrial SOD2)
• up-regulation of GADD 45A ( DNA repair)
• increase of the epidermal growth & wound healing (FGF7)
Consumer evaluation:
Backs up skin feeling and healthy appearance
China
2015
INCI names: water (and) Macrocystis pyrifera extract (and) Hydrolyzed
Yeast extract
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EYE CONTOUR CARE
for tightening reducing fine lines , under eye puffiness and dark circles
Takes care of the delicate area around the eyes
PHYCO’DERM®
Stimulates the major defense systems for increasing resistance
against environmental stressors
• protection against microbial infections & associated
inflammation
• protection against oxidative stress, regulation of cellular
redox state
• reinforcement of detoxification systems
3% -5%
improves dermis properties for reversing skin ageing
• up-regulation of genes involved in cell adhesion, hyaluronan
synthesis, down regulation of MMP 1- MMP14 - MMP11
genes
• stimulation of fibroblast proliferation
• stimulation of Type I collagen synthesis
Clinical studies:
China
2015
attenuates fine lines and wrinkles of crow’s feet
Minimizes the appearance of dark circles under the eyes
Reduces the volume of under-eye bags for alleviating puffiness
INCI names: water (and) glycerin (and) Undaria pinnatifida extract (and)
Corallina officinalis extract
SKIN HYDRATION
for maintaining skin hydration & water balance
MIRUAL
Marine moisturizer & cell protector
1.25% -10%
Nourishes the skin and helps to reconstitute the NMF
Maintains healthy moisture balance
Invigorates cell metabolism
Adapts its behaviour to free radical protection
Clinical studies:
Improves skin hydration
China
2015
INCI names: water (and) Codium fragile extract
SEA MOIST COMPLEX
Fights back against dry skin by replenishing depleted
moisture
1% - 5%
Synergistic action with glycerin
• reinforcement of the hydration properties of glycerin
Ameliorates the epidermal functions of dry skin
Clinical studies:
Improves hydration in dry skin
INCI names: glycerin (and) water (and) Kappaphycus alvarezii extract
(and) sea water
China
2015
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SKIN BARRIER
for minimizing TEWL & roughness
Strengthens the skin’s barrier function
ALGOMEGA NP
Re-equilibrates lipid deficient skin due to its balanced
composition in polyunsaturated fatty acids (omega-3, omega-6)
3% - 5%
Reinforces the skin barrier function
Decreases skin desquamation
Restores the structure of cell membranes after barrier function
damage caused by an irritant agent
Clinical studies:
Improves skin hydration and reduces water loss
INCI names: Silybum marianum seed oil (and) Nannochloropsis oculata
extract (and) Porphyra umbilicalis extract
SKIN ENERGIZING
for increasing cellular metabolism
SEAVIE
A marine-derived answer for invigorating skin due to
its nourishing composition
0.2% - 2%
Offers the skin intense nutrition for revitalizing it
Guarantees cells life expectancy in food starved conditions
Improves the cellular energetic status
• stimulation of the intracellular ATP synthesis
Protects the mitochondria of skin cells and keeps its
functionality
China
2015
INCI names: water (and) Fucus serratus extract
SKIN REPAIRING
for restoring skin integrity
Marine enhancer of skin repair
Regulates the major phases of skin regeneration
OCEA CARE
1% - 5%
• increase of the differentiation of fibroblasts into
myofibroblasts (overexpression of actins & integrins genes)
• stimulation of remodelling
• activation of essential growth factors (PDGF-EGF-IGF1)
Boosts the proliferation of skin cells
Clinical studies:
Favors skin’s natural recovery & increases skin hydration
Improves superficial skin imperfections
China
2015
INCI names: glycerin (and) water (and) Laminaria saccharina extract
(and) L-arginine
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SEBUM REGULATION
for oil control
The effective marine sebum regulator
SEBOCEA
Decreases sebum production
• inhibition of 5α-reductase
PATENTED
1% - 3%
Limits the resulting irritation
• inhibition of IL-8 and TNF α
Clinical studies & consumer evaluation:
Decreases the sebum spots number
Improves the comfort of the oily skin
INCI names: water (and) Fucus spiralis extract (and) Tetraselmis chui
extract.
SLIMMING
for shaping and contouring fatty areas
Reshapes the silhouette & prevents the loss of firmness
SLENDYL
Banishes fat deposits by acting on the three main pathways
Action on adipogenesis (mature adipocyte formation)
1% - 4%
Blocks adipocyte differentiation by reducing the capacity to
store fats in pre-adipocytes through multiple ways of action
• locks precursors recruitment and regulates differentiation at
different time points
• triggers the induction of key transcriptions factors
• controls the transport/oxidation of fatty acids
• inhibits lipid accumulation during pre-adipocytes maturation
Action on lipogenesis
Regulates lipogenesis by preventing the formation of new
adipocytes and thus fat storage
Action on lipolysis
Stimulates the lipolysis by promoting triglycerides breakdown
in adipocytes
China
2015
Firms up the skin naturally
• reinforces the properties of dermis by stimulating Type I
collagen synthesis
Clinical studies:
reduces the shape/morphology of the thighs for
refining the silhouette
INCI names: water (and) Himanthalia elongata extract (and) Undaria
pinnatifida extract
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PROTECTION - DETOXIFICATION
For preventing damage against reactive species & free radicals
Advanced scavenger of reactive species
From green vegetative cells cultured in optimal conditions
ASTAPLANCTON
G8
0.5% - 2%
Protects against reactive oxygen species (ROS)
• scavenging activity
Protects DNA against singlet oxygen & hydroxyl radical
Captures reactive carbonyl species (RCS), mediators of carbonyl
stress
• protection of proteins from oxidation
• preservation of the fine cell structure against RCS induced
damage
China
2015
Complementary benefits with ASTAPLANCTON HA
INCI names: water (and) Haematococcus pluvialis extract (and) sea water
The best radical scavenger from the Mediterranean
SEA HEATHER
Combats damage induced by the both pathways of the lipid
peroxidation
PATENTED
2% - 10%
• action on the no enzymatic pathway
protection against cellular lysis due to superoxide
anion, hydrogen peroxide, alkoxyl radical, singlet
oxygen and hydroxyl radical
• action on the enzymatic pathway
anti- inflammation activity
Protects DNA against superoxide anion & hydrogen peroxide
Guarantees full cell membrane functionality after chemicalinduced irritation
China
2015
Clinical studies:
Lowers skin reactivity by reducing stinging sensations
INCI names: water (and) Cystoseira amentacea/caespitosa/brachycarpa
PROTECTION - DETOXIFICATION
for preventing damage against pollution and extreme environmental conditions
PATENTED
KIMARINE
Takes the offensive against city pollution
2% - 5%
Protects against free radicals and UVA-induced damage
Protects against urban pollution
• action against cigarette smoke, exhaust fumes, heavy
metals (cadmium, lead)
INCI names: water (and) Undaria pinnatifida extract
China
2015
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Safeguards
conditions
OROSEA
the
skin
against
extreme
environmental
PATENTED
Strengthens the skin’s defence from outside aggressions
0.5% - 3%
Protects against extreme conditions (heat-cold-osmotic stress)
Improves thermotolerance by modulating the gene expression
involved in cellular defence against heat stress (heat shock
response, cellular redox regulation, cell apoptosis prevention,
antioxidant protection, inflammation prevention) thus leading
to enhanced survival and reduced damage
Clinical studies:
Provides the skin comfort via moisturizing after unique
application for at least 8h
Improves the skin’s appearance after two days applications only
INCI names: water (and) Rissoella verruculosa extract
PATENTED
PHYACTYL
A detoxifying agent from marine origin
2% - 5%
Protects against the most harmful ROS
• action against singlet oxygen, superoxide anion, hydrogen
peroxide & hydroxyl radical
Protects DNA against singlet oxygen & hydroxyl radical
Protects against ozone & chemical stress (sodium lauryl
sulphate)
INCI names: water (and) Sargassum muticum extract
China
2015
SOOTHING – ANTI-INFLAMMATION – SENSITIVE SKIN
for protecting and calming reactive skin
Marine immunity booster for improving the comfort of
fragile and vulnerable skin
OCEA
DEFENCE
2%
Reinforces the cutaneous shield
• boosts the innate immune system
• regulates the protective damage mechanisms linked to
cellular homeostasis and oxidative stress
• protects the connective tissue from degradation
• protects against DNA strand breaks from UVA/visibleinduced damage (Comet assay)
• keeps inflammation under control
Clinical studies:
China
2015
Reduces UV-induced redness with a short term efficacy
INCI names: caprylic capric triglycerides (and) Laminaria ochroleuca
extract (and) tocopherols
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Offers efficient protection to irritated skin
EFFICIENSEA
Protects DNA against singlet oxygen-induced damage
PATENTED
1% - 5%
Keeps inflammation under control
• inhibition of phospholipase A2, 5-lipoxygenase & IL 1α
Complementary properties
• protection against UVB radiation
• inhibition of elastase properties
Clinical studies:
Attenuates skin irritation (stinging sensations)
China
2015
INCI names: water (and) Pelvetia canaliculata extract
The best radical scavenger from the Mediterranean
PATENTED
SEA
HEATHER
Combats damage induced by the both pathways of the lipid
peroxidation
• action on the nonenzymatic pathway
protection against cellular lysis
2% - 10%
• action on the enzymatic pathway - anti- inflammation
activity
protection against phospholipase A2 – 5-lipoxygenase
Protects DNA against superoxide anion & hydrogen peroxide
Guarantees full cell membrane functionality after chemicalinduced irritation
China
2015
Clinical studies:
Soothes skin irritation and reduces stinging sensation
INCI names: water (and) Cystoseira amentacea/caespitosa/brachycarpa
TANNING – SKIN GLOW
for developing a more natural tan
BRONZ’ALG
For a sun-kissed & healthy complexion all year round
Regulates the major genes of melanogenesis pathways (MITF
factor and melanogenic enzymes TYR & TYRP-1, Wnt/catenin,
endothelin/protein kinase pathways, involvement in
melanocytes-keratinocytes interactions)
PATENTED
0.5 % - 5 %
Protects against UVA/UVB-induced damage
Promotes skin pigmentation independent to sun exposure
Clinical studies:
Accelerates tanning
Revives dull skin for a glowing appearance
INCI names: water (and) Bifurcaria bifurcata extract (and) acetyl- tyrosine
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SUN CARE
for protecting against UV damage
HELIONORI
Acts as a genuine UVA bioprotector against UVA induced
skin alterations
PATENTED
Unique resource in mycosporines-like amino acids MAAs
(natural marine UV filters)
1% - 4%
Provides a safe marine alternative to synthetic UVA filters
(stable to intense solar light and heat exposure)
Prevents the formation of sun burn cells
Protects cell metabolism against UVA irradiation
Protects DNA (Comet assay on human melanocytes) & cell
membranes against UVA
China
2015
INCI names: water (and) Porphyra umbilicalis extract
ASTAPLANCTON
HA
Astaxanthin helps for potent UVA-UVB protection
0.5% - 2%
From red, non motile resting cells accumulating the pigment
astaxanthin under inductive high light intensity (sunlight)
Protects against UVA & UVB
Stimulates the cellular metabolism
Shows anti-oxidant protection superior to that of tocopherol
Complementary benefits with ASTAPLANCTON G8
China
2015
INCI names: Helianthus annuus (Sunflower) seed oil (and) Haematococcus
pluvialis extract
Helps shield your skin against damaging effects
of sun exposure
2% - 5%
SUN’ALG
Strengthens the skin’s defence mechanisms by up-regulating
genes involved in oxidative stress, DNA repair, skin defense and
barrier function
Offers high protection against both UVA and UVB radiation
Prevents the formation of sun burn cells
Fights against inflammatory skin reactions
Clinical studies:
Diminishes redness and soothes sunburns (erythema)
China
2015
INCI names: Pongamia glabra seed oil (and) Dunaliella salina /
Haematococcus pluvialis extract
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SKIN LIGHTENING
for regulating skin pigmentation
LIGHTOCEANE
Potent skin lightener from the Ocean
PATENTED
Influences all main pathways involved in melanogenesis
• before melanin synthesis
reduction of the production of nitric oxide NO
1% - 3%
• during melanin synthesis
inhibition of tyrosinase & melanin synthesis
• after melanin synthesis
control of melanosome transfer to keratinocytes
Complementary properties:
• protection against free radicals and UVA/UVB irradiations
• protection against inflammation (inhibition LOX –IL1 α)
• protection against protease deterioration anti-collagenaseanti-elastase & anti-hyaluronidase properties)
INCI names: water (and) Halidrys siliquosa extract
LIGHTOCEANE
G40
INCI names: glycerin (and) water (and) Halidrys siliquosa extract
GELYOL® LINE
standardised & concentrated hydroglycolic seaweeds extracts
anti-oxidant & slimming properties
GELYOL® AN
55
INCI names: butylene glycol (and) water (and)
Ascophyllum nodosum extract
remineralizing & revitalising properties
GELYOL® GS
45
INCI names: butylene glycol (and) water (and)
Gelidium sesquipedale extract
(Gelidium cartilagineum extract)
moisturizing & osmoregulating properties
GELYOL® LN
25
INCI names: butylene glycol (and) water (and)
Lessonia nigrescens extract
0.5% - 3%
China
2015
2% - 5%
China
2015
1% - 3%
China
2015
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SUSTAINABILITY PRINCIPLES
Understanding where seaweeds present in our products as raw materials come from is a priority for us.
This is demonstrated by:
strict selection for optimal quality and traceability of sourcing algal biomass from field as well as from cultivation
correct systematic determination of species in agreement with the Botanical code of International nomenclature and the
currently accepted names by Algae base (www.algaebase.org)
environmental responsibility for the conservation of natural resources and the algal biodiversity in order to insure the
regeneration of algal biomass, reduce environmental operational impacts and contribute to the health of aquatic
ecosystems
responsible considerations of partnerships with local experienced harvesters and well-trained international producers
ensuring the sustainability of the valuable resource and its ecosystem in order to minimize the social footprint of
commercial production in agreement with Nagoya Protocol
strict compliance of resource management with laws and regulations e.g. EU Nature directives (Natura 2000) – CITES
(Washington Convention)
optimization of manufacturing process within eco-responsible guidelines.
Our sourcing sites are presented here after.
ATLANTIC OCEAN (EUROPE)
Ascophyllum nodosum
Bifurcaria bifurcata
Corallina officinalis
Fucus serratus
Fucus vesiculosus
Gelidium sesquipedale
Halidrys siliquosa
Halopteris scoparia
(Stypocaulon scoparium)
Himanthalia elongata
Laminaria ochroleuca
Laminaria saccharina
(Saccharina latissima)
Porphyra umbilicalis
SOUTH PACIFIC OCEAN
Lessonia nigrescens
Macrocystis pyrifera
ATLANTIC OCEAN (AFRICA)
Meristotheca dakarensis
(Meristotheca senegalensis)
INDIAN OCEAN
Cultivation
Caulerpa lentillifera
Kappaphycus alvarezii
MEDITERRANEAN
Cosmopolite element
Jania rubens
Endemic element
Cystoseira sp.
Rissoella verruculosa
Invasive sp. (Aliens)
Codium fragile
Sargassum muticum
Undaria pinnatifida
MICROALGAE
Cultivation
France-Spain- Hawaii-Australia
Dunaliella salina
Haematococcus pluvialis
Nannochloropsis oculata
Tetraselmis chui
Our ultimate goal is to deliver consumers visible benefits with a main challenge that combines innovation and
efficiency with sustainability and respect of the algal biodiversity.
GELYMA
Parc d’Affaires Marseille Sud (C4) - 1 Boulevard de l’Océan - 13009 Marseille - France
Phone: +33 4 96 14 09 82 - Fax: +33 4 96 14 09 83 - E-mail: [email protected] - contact @gelyma.com
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