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Viruses and Prokaryotes Chapter 21 Part 2 21.6 The Bacteria Bacteria are the oldest, most diverse, and most abundant prokaryotic lineage Most are harmless or benefit us by releasing oxygen, fixing nitrogen, or cycling nutrients Some bacterial chemoheterotrophs cause disease in humans Heat Lovers Thermophiles are an old lineage that live in volcanic springs or deep-sea hydrothermal vents Heat-stable DNA polymerase from Thermus aquaticus was used in the first polymerase chain reactions Cyanobacteria Chloroplasts evolved from ancient cyanobacteria • Put oxygen in Earth’s atmosphere Nitrogen fixation • Some cyanobacteria form heterocysts that fix atmospheric nitrogen (N2) into ammonia (NH3) resting spore heterocyst 6 µm Fig. 21-12, p. 342 Metabolically Diverse Proteobacteria Thiomargarita namibiensis strips electrons from sulfur Helicobacter pylori causes stomach ulcers Magnetotactic bacteria detect magnetic fields Myxobacteria form multicelled fruiting bodies Metabolically Diverse Proteobacteria 0.2 mm Fig. 21-13a, p. 343 1 µm Fig. 21-13b, p. 343 magnetite Fig. 21-13c, p. 343 capsule with resting cells Fig. 21-13d, p. 343 The Gram-Positive Heterotrophs Gram-positive bacteria have thick walls that stain purple by Gram-staining • Thin-walled bacteria (Gram-negative) stain pink Lactobacillus fermentation reactions produce yogurt and other foods Some form endospores in unfavorable conditions, and make deadly toxins • Anthrax, tetanus, botulism Gram-Positive Bacteria DNA spore coat capsule around cell wall Fig. 21-14b, p. 343 Spirochetes and Chlamydias Spirochetes are spring-shaped • Example: Borrelia burgdorferi (pathogen that causes Lyme disease) carried by ticks (vectors) Chlamydias are intracellular parasites • Example: C. trachomatis, a common cause of sexually transmitted disease 21.6 Key Concepts The Bacteria Bacteria are the most abundant prokaryotic cells on Earth Bacteria perform important services such as degrading wastes, adding oxygen to the air, and providing essential nutrients to plants Nearly all disease-causing prokaryotes are bacteria 21.7 The Archaeans Archaeans, the more recently discovered prokaryotic lineage, are the third domain – the closest prokaryotic relatives of eukaryotes Archaeans live everywhere – many live in very hot or very salty habitats Hardly any archaeans cause human disease Archaean Physiology Methanogens (methane producers) • Strict anaerobes Extreme halophiles (salt lovers) • Aerobic or photosynthetic Extreme thermophiles (heat lovers) • Chemoautotrophs or heterotrophs Methanogenic Archaeans 0.5 µm Life in Extreme Environments Fig. 21-17a, p. 345 5 µm Fig. 21-17b, p. 345 Fig. 21-17c, p. 345 Fig. 21-17d, p. 345 21.7 Key Concepts The Archaeans Archaeans are the more recently discovered, less studied prokaryotic group Some show a remarkable ability to survive in extreme habitats, but others live in more ordinary places They play important roles in ecosystems 21.8 Evolution and Infectious Disease Infection occurs when pathogens enter the internal environment and multiply Disease follows when the pathogen’s activities interfere with normal body functions Viruses, bacteria, and other pathogens evolve by natural selection, as do their hosts Deaths From Infectious Diseases The Spread of Diseases Sporadic diseases • Occur irregularly, affect few people Epidemic diseases • Spread quickly, then subside Endemic diseases • Occur continually, but don’t spread far Pandemic diseases • Break out and spread worldwide The SARS Epidemic An Evolutionary Perspective Two barriers prevent pathogens from dominating • Species that coevolve with specific pathogens have built-in defenses • A pathogen that kills its host too fast might disappear along with the host Emerging Diseases Animals in remote habitats carry dangerous pathogens that have not coevolved with humans • HIV, SARS, Ebola, and H5N1 avian influenza all came from close contact with animals • A bird flu caused the 1918 pandemic that killed 50 million people The Threat of Drug-Resistance In a population of pathogens, drug-resistant individuals survive and reproduce • About half the known strains of Streptococcus pneumoniae are penicillin resistant • Many strains of HIV are now resistant to the antiviral drugs used to fight them It’s a Small World In this age of global air travel and constant human migrations, it is difficult to contain the spread of dangerous pathogens Which is Deadlier? Ebola kills up to 90% of those infected, but is sporadic; Mycobacterium tuberculosis kills 50%, but is widespread and drug resistant 400 nm Fig. 21-19a, p. 347 0.5 µm Fig. 21-19b, p. 347 21.8 Key Concepts Evolution and Disease An immense variety of pathogens, or diseasecausing agents, infect human hosts Pathogens and their hosts coevolve; each acts as a selective agent on the other Animation: Body plans of viruses three major processes: conjugation, transformation, and transduction Animation: Enveloped DNA virus replication Animation: Examples of Eubacteria Animation: Gram staining Animation: Prokaryotic body plan ABC video: Bird Flu ABC video: Germs in Pakistan ABC video: Mask of Technology ABC video: AIDS Conference in Brazil ABC video: Beach Pollution ABC video: Polio Scare ABC video: The Problem with Pork ABC video: World AIDS Day Video: The face of AIDS