Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Medical Biology Lec -4- Shorooq Wessam Spermatogenesis Spermatogenesis is the process by which male spermatogonia develop into mature spermatozoa .spermatozoa are the mature male gametes,in many sexually reproducing organisms .Thus ,spermatogensis is the male version of gametogensis.The entire process permatogenesis produces mature male gaemes,commonly called sperm but specifically Known as spermatozoa ,which are able to fertilize the counterpart female gamete ,the oocyte,during conception to produce a single-celled individual known as a zygote .Spematogenasis takes place wihin several structures of the male reproductive system .the initial stages occur within the testis and progress to the epididymis where the developing gametes are stored until ejaculation .The seminiferous tubules of the testes are the starting point for the process ,where stem cells adjacent to the inner tubule wall divide in a centripetal direction beginning at the walls and proceeding into the innermost part or lumen to produce immature sperm .maturation occurs in the epididymis and involves the acquisition of a tail and hence motility. spermatocytogenesis is the male form of gametocyogenesis and results in the formation of sparmatocytes possessing half the normal complememt of genetic material. in spermatoytogenesis diploid….divides mitotically to produce adiploid intermediate cell called a primary spermatocyte .each prim spermatocyte duplicates its DNA and subsequently undergoes meiosis I to produce two haploid secondary spermatocytes.This division implicates sources of genetic variation, such as random inclusion of either parerntal chromosomes ,and chromosomal crossover ,to increase the genetic variability of the gamete. 1 Oogenesis in mammals It is interesting to note that such an important process in animal life cycles is done completey without he aid of spindle – coordinating centrsosomes. It consists of several process : oocytogensis , ootidogenesis and the final maturity to form an ovum. Folliculogenesis is a separate process during ootidogenesis . the creation of oogonia traditionally doesn’t belong to oogenesis , but to the common path of gametogenesis together with spermatogensis . 2 3 Lows of thermodynamics Energy exists in many forms such as heat , light , chemical energy and electrical energy . energy is the ability to bring about change or to do work . thermodynamics is the study of energy . in bioenergetics the cells convert potential energy , usually in the form of C-C covalent bonds or ATP molecules into kinetic energy to accomplish cell division , growth , biosynthesis and active transport among other things . First law of thermodynamics : energy can be changed from one form to another but it cannot be created or destroyed . the total amount of energy and matter in the universe remains constant , merely changing from one form to another . the first low of thermodynamics (conservation) states that energy is always conserved , it cannot be created or destroyed Second low of thermodynamics : states that "in all energy exchanges if no energy enters or leaves the system , the potential energy of the state will always be less than that of the initial state" . this is also commonly referred to as entropy , awatch spring – driven watch will run until the potential energy in the spring is converted and not again until energy is reapplied to the spring to rewind it . A car that has run out of gas will not run again until you walk 10 miles to a gas station and refuel the car . one the potential energy locked in carbohydrates is converted into kinetic energy (energy in use or motion) , the organism will get no more until energy is input again. In the process of energy transfer some energy will dissipate as heat entropy is a measure of disorder : cells are not disordered and so have low entropy . the flow of energy maintains order and life , entropy wins when organisms cease to take in energy and die. Ctabolism and Anabolism Anabolism is the total series of chemical reactions involved in synthesis of organic compounds . autotrophs must be able to manfacture (synthesize) all the organic compounds they need heterotrophs can obtain some of their compounds in their diet (along with their energy) . for example humans can synthesize 12 of the 20 amino acids , we must obtain the 4 other 8 in our diet .catabolism is the series of chemical reactions that breakdown larger molecules . energy is released this way , some of it can be utilized for anabolism , products of catabolism can be reassembled by anabolic processes ito new anabolic molecules . Endrogonic and Exergonic Energy releasing processes , ones that "generate" energy are termed exergonic reactions. Reactions that require energy to initiate the reaction are known as endergonic reaction . all natural processes tend to proceed in such a direction that the disorder or randomness of the universe increase (the second law of thermodynamics).Biochemical reactions in living organisms are essentially energy transfers .often they occur together , "linked" , in what are referred to as oxidation reduction reactions Reduction is the gain of an electron . sometimes we also havefor the ride , H ions along for the ride , so reduction also becomes the gain of H . oxidation is the loss of an electron (or hydrogen). In oxidation /reductions , one chemical is oxidized and its electrons are passed to another (reduced, then) chemical. Such coupled reactions are referred to as redox reactions , the metabolic processes glycolysis , krebs cycle and electron transport phosphorylation involved the transfer of electrons (at varying energy states) by redox reaction. 5