Download Skin Care Presentation - Part one

Cutaneous Lymphoma and
Skin Maintenance:
Guidelines
Tara Jennings, BA
Clinical Research Fellow
Department of Dermatology & Cutaneous
Biology
Thomas Jefferson University
Objectives
• Overview of Skin Biology and Cell Turnover
• Maintaining healthy skin: Why is this
important?
• Skin care guidelines for patients with
Cutaneous Lymphoma
Function of our Skin
Largest organ in our body
•Most important protection against
environmental influences
• Temperature Regulation
• Sensation
Protection From:
•Microbes, bacteria
•Dehydration
•UV light
•Cuts and Bruises
•Extreme Temperatures
http://www.woundcare-bbraun.com/cps/rde/xchg/om-woundcare-en-int/hs.xsl/7507.html
Layers of Skin
THREE LAYERS
EPIDERMIS
•External layer
responsible for
“waterproofing” and
protection
DERMIS
•Contains connective
tissue, sweat glands,
blood vessels, and hair
follicles
HYPODERMIS
•Subcutaneous (fat)
layer
Epidermis
Keratinocytes
•Made of Keratin
•Differentiate from
Stratum Basale to
Stratum Corneum
•Slowly lose
nuclei and
become dead
cells
(Corneocytes)
Stratum Corneum
Stratum Granulosum
Stratum
Spinosum
Stratum Basale
Desquamation
• Cells shed in order to
maintain barrier
• New cells replace old
• total epidermis is replaced
every 28 days
• Majority of dust in the
world is actually dead
skin!
Stratum Corneum
Composed of Corneocytes & Lipids (Brick and Mortar
Structure)
•Intracellular Lipids: form water-resistant barrier
• Ceramides, Fatty Acids, Cholesterol
• Selective permeability
•Corneocytes
NMF
• Dead cells composed of keratin (give cell structure and elasticity)
and Natural Moisturizing Factor
Corneocyt
e
Intercellular
Lipids
Natural Moisturizing
Factor
• Found only in the Stratum
Corneum
• Allow us to take up and
release water
– Maintains skin hydration
– Attracts water from
atmosphere
– Maintains skin elasticity
– Regulates Desquamation
• Production decreases with
Age
Objectives
• Overview of Skin Biology and Cell Turnover
• Maintaining healthy skin: Why is this
important?
• Skincare guidelines for patients with
Cutaneous Lymphoma
Why is Gentle Skin Care
important?
• Preventing Dry Skin Stopping the itch!
– Maintaining quality of
life
– Preventing Infection
Preventing Infection:
Skin as a Barrier
• Lymphocytes reside in
the dermis
– recognize and kill foreign
materials
• Two types of
lymphocytes
– B-Cells: Make antibodies
– T Cells:
• Helper T: Help activate BCells to make antibodies
• Cytotoxic T: Directly kill
foreign bodies
Immunosuppression in
patients with cutaneous
lymphoma
• T-cells and B-cells that normally reside in
the skin become malignant
• Normal T/B cells are outnumbered and
cannot do their job
http://www.skinrepair.uk.com/wp-content/uploads/2013/12/skin-barrier-reapir-cropped-Page_1.jpg
Microorganism
s
Why is Gentle Skin Care
important?
• Stopping the itch!
– Maintaining quality of
life
– Preventing Infection
– Preventing
Disease
Progression
Why is Gentle Skin Care
important?
• Stopping the itch!
– Maintaining quality of
life
– Preventing Infection
– Preventing
Disease
Progression
– Dry skin can make recognizing
lesions more difficult
• In order to efficiently treat and track your
disease, we need to know your disease
burden
BEFORE
AFTER VASELINE
Outline of Presentation
• Overview of Skin Biology and Cell Turnover
• Maintaining healthy skin: Why is this
important?
• Skincare guidelines for patients with
Cutaneous Lymphoma
Gentle Skincare Guidelines
1. Changing your shower habits
2. Moisturizing
3. Gentle Skincare and your Treatment Regimen
Changing your Shower
Habits
1. Duration and Temperature
• 5 minute Showers
• Avoiding Hot Water
Avoiding Long
Showers/ Hot water
• Skin is extremely
sensitive to excessive
moisture
• Water-protectant film
becomes destroyed
– Cells swell up
– Lipids in top layer are
removed
– Dry/Cracked Skin