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Basic CT Physics Christina L. Sammet, Ph.D., DABR Medical Physicist, RSO/LSO Research Assistant Professor, Northwestern University Disclosures • I am a member of the Bayer HealthCare Informatics Global Advisory Board. 2 Outline 1.) Current technology for cardiac CT imaging 2.) What influences radiation dose in cardiac imaging? 3.) What do these radiation units mean? 4.) How is radiation dose calculated in CT imaging? 3 Outline 1.) Current technology for cardiac CT imaging 2.) What influences radiation dose in cardiac imaging? 3.) What do these radiation units mean? 4.) How is radiation dose calculated in CT imaging? 4 Current technology for Cardiac CT imaging 5 Axial vs. Helical Scanning Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012 6 Axial vs. Helical Scanning Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012 7 Dual Source CT Scanner Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012 8 Volume Scanners Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012 9 Outline 1.) Current technology for cardiac CT imaging 2.) What influences radiation dose in cardiac imaging? 3.) What do these radiation units mean? 4.) How is radiation dose calculated in CT imaging? 10 What influences radiation dose in cardiac imaging? 11 Z-axis dose modulation Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012 12 Z-axis dose modulation Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012 13 “On the fly” Dose Modulation Vendor GE Philips Siemens Toshiba Longitudinal Tube Current Modulation Auto mA Z-modulation (ZDOM) CareDose N/A Longitudinal + Angular Tube Current Modulation Smart mA 3D Modulation (DDOM) CareDose 4D Sure Exposure 3D Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012 14 Prospective vs. Retrospective Cardiac Gating Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012 15 Beam Shaping Filter Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012 16 Beam Shaping Filter Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012 17 Outline 1.) Current technology for cardiac CT imaging 2.) What influences radiation dose in cardiac imaging? 3.) What do these radiation units mean? 4.) How is radiation dose calculated in CT imaging? 18 What do these radiation units mean? 19 Absorbed Dose and the “Gray” • Gray = Joule/kilogram = Energy/unit mass • Physical quantity, and does not take into account any biological context • Diagnostic imaging procedures are in the mGy range • mGy is unit used for organ doses, CTDI and SSDE 20 Effective Dose and the “Sievert” • Derived unit of radiation that is a measure of the health effect of low levels of ionizing radiation on the human body. • The Sievert represents the probability of radiation induced carcinogenisis and genetic damage • Diagnostic imaging procedures are in the mSv range • mSv is used exclusively for effective doses • Dependent on the organs exposed and the age of patient 21 Radiobiology https://www.med-ed.virginia.edu/courses/rad/radbiol/02bio/bio-04-01.html 22 Radiobiology Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012. 23 Radiobiology Bushberg JT, et al. The Essential Physics of Medical Imaging, Wolters Kluwer, Philadelphia, 3rd Edition, 2012. 24 Pediatric Radiosensitivity • According to ICRP publication 103 (2007) the excess relative risk of cancer for the adult population is 4.1 - 4.8% per Sv. • Children have a higher relative risk when compared to adults due to their increased growth rate and ongoing cellular differentiation. • Depending on the age of exposure, children have a lifetime risk of radiation-induced carcinogenesis 2-3 times higher than adults. Pediatric Radiosensitivity • Reference: Donald J. Peck and Ehsan Samei, Image Wisely “How to Understand and Communicate Radiation Risk”, Image Wisely, ACR (2010). 26 Outline 1.) Current technology for cardiac CT imaging 2.) What influences radiation dose in cardiac imaging? 3.) What do these radiation units mean? 4.) How is radiation dose calculated in CT imaging? 27 How is radiation dose calculated in CT imaging? 28 Dose in CT • The relatively simple geometry and method of calculating dose in radiography is not applicable to CT where there are thousands of projections. • A new method of dosimetry is needed and is currently under development by the medical physics community • Though not an ideal method of patient dosimetry, currently CT Dose reports include the parameters Computed Tomography Dose Index (CTDIvol) and the Dose-Length-Product (DLP). Bushberg, Jerrold, et al. The Essential Physics of Medical Imaging. Philadelphia, 2012. CT Dose Report Examples CTDIvol CTDIvol is the dose delivered by the selected protocol to a SINGLE SLICE of a plastic cylinder. Bushberg, Jerrold, et al. The Essential Physics of Medical Imaging. Philadelphia, 2012. CTDIvol CTDIvol does not factor in ANY information about the patient. Bushberg, Jerrold, et al. The Essential Physics of Medical Imaging. Philadelphia, 2012. CTDIvol Very important point about CTDIvol in Pediatric Imaging! • The phantom sizes used to estimate the CTDIvol may be inappropriate for pediatric sized patient. • For Instance, a body protocol that references a 32cm CTDI phantom will grossly underestimate the dose for a small ped (usually assumed to be about a factor of two). • Most methods that convert Dose Length Product to Effective Dose attempt to correct for patient size. SSDE 34 CTDIvol Other Important things to remember about CTDIvol • The CTDIvol displayed on the scanner before the Topogram (ie. such as when you are building a protocol) will be only dependent on the technique and the phantom used (16cm or 32cm). Therefore, it will not accurately reflect the patient dose. • If you have a scanner with dose modulation that uses the topogram to estimate patient thickness, you will notice that the CTDIvol will adjust to reflect the anticipated decreased (or increased dose). • You will get yet another CTDIvol number in the dose report. This will reflect the dose modulation based on the topogram (what you saw right before you scanned) and the “on-the-fly” dose modulation. DLP • Dose Length Product is just the product of CTDIvol and the length of the scan in the z-axis. • DLP has units of mGy*length • DLP is takes into account the length of the anatomy that was exposed and is used for effective dose calculations What can be done with DLP? • • • • • “Shrimpton” Method “Deak” Method Alessio Online Calculator ImPact Calculator “Huda” Method AJR:199, August 2012. Example: The Deak Method Radiology: Volume 257: Number 1—October 2010. Example: The Deak Method Conversion of Effective Dose to Cancer Risk? . Bushberg, Jerrold, et al. The Essential Physics of Medical Imaging. Philadelphia, 2012 Conversion of Effective Dose to Individual Patient’s Cancer Risk? Big No-No!!! Risk estimates apply to a population that would be exposed to that effective dose, not the individual! When communicating with patients it is better to convert effective doses to background radiation or another familiar source of radiation. Thank you! Christina L. Sammet, Ph.D., DABR Email: [email protected] 44