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Cardiovascular System 1 EDU2HBS Human Body Systems 2 EDU2HBS Human Body Systems The Cardiovascular System A closed system of the heart, blood and blood vessels  The heart pumps blood  Blood vessels allow blood to circulate to all parts of the body The function of the cardiovascular system is 3 EDU2HBS Human Body Systems The Blood (Physical Characteristics)  Color range  pH must remain between 7.35–7.45  Blood temperature is slightly higher than body temperature 4 EDU2HBS Human Body Systems Blood Plasma  Includes many dissolved substances  Nutrients  Salts (metal ions)  Respiratory gases  Hormones  Proteins  Waste products EDU2HBS Human Body Systems 5 Erythrocytes (Red Blood Cells)  Outnumber white blood cells 1000:1  Contain a protein chemical called hemoglobin  Make blood bright red  Contains the element iron which carries oxygen 6 EDU2HBS Human Body Systems Leukocytes (White Blood Cells) Platelets  occurs when blood vessels are ruptured. 7 EDU2HBS Human Body Systems The Heart  Location  Thorax between the lungs  Pointed apex directed toward left hip  About the size of your fist 8 EDU2HBS Human Body Systems The Heart: Coverings  Pericardium – a double walled membrane  Visceral pericardium  Parietal pericardium  Serous fluid fills the space between the layers of pericardium 9 EDU2HBS Human Body Systems The Heart: Heart Wall  Three layers  Epicardium  Outside layer  This layer is the parietal pericardium  Myocardium  Middle layer  Endocardium  Inner layer 10 EDU2HBS Human Body Systems External Heart Anatomy 11 EDU2HBS Human Body Systems The Heart: Chambers  Four chambers  Atria  Receiving chambers  Right atrium  Left atrium  Ventricles  Discharging chambers  Right ventricle  Left ventricle 12 EDU2HBS Human Body Systems Blood Circulation 13 EDU2HBS Human Body Systems The Heart: Valves  Four valves  Atrioventricular valves – between atria and ventricles  Mitral valve (left)  Tricuspid valve (right)  Semilunar valves between ventricle and artery  Pulmonary semilunar valve  Aortic semilunar valve 14 EDU2HBS Human Body Systems The Heart: Valves  Valves open as blood is pumped through  Close to prevent backflow 15 EDU2HBS Human Body Systems Coronary Circulation  The heart has its own nourishing circulatory system  Coronary arteries  Cardiac veins  Blood empties into the right atrium via the coronary sinus EDU2HBS Human Body Systems 16 The Heart: Conduction System  Intrinsic conduction system (nodal system)  Heart muscle cells contract, without nerve impulses, in a regular, continuous way 17 EDU2HBS Human Body Systems 18 EDU2HBS Human Body Systems Heart Contractions  Sequential stimulation occurs at other autorhythmic cells  AV node  AV bundle  Bundle branches  Purkinje fibres 19 EDU2HBS Human Body Systems The Heart: Cardiac Output  Cardiac output (CO)  CO = (heart rate [HR]) x (stroke volume [SV])  Stroke volume 20 EDU2HBS Human Body Systems The Heart: Regulation of Heart Rate  Starling’s law of the heart – the more that the cardiac muscle is stretched, the stronger the contraction  Changing heart rate is the most common way to change cardiac output 21 EDU2HBS Human Body Systems The Heart: Regulation of Heart Rate Increased heart rate  Sympathetic nervous system  Crisis  Low blood pressure  Hormones  Epinephrine  Thyroxine  Exercise  Decreased blood volume 22 EDU2HBS Human Body Systems The Heart: Regulation of Heart Rate Decreased heart rate  Parasympathetic nervous system  High blood pressure or blood volume  Decreased venous return 23 EDU2HBS Human Body Systems Blood Vessels: The Vascular System  Taking blood to the tissues and back  Arteries  Arterioles  Capillaries  Venules  Veins 24 EDU2HBS Human Body Systems Differences Between Blood Vessel Types  Walls of arteries are the thickest  Lumens of veins are larger  Walls of capillaries are only one cell layer thick to allow for exchanges between blood and tissue 25 EDU2HBS Human Body Systems Movement of Blood Through Vessels  Most arterial blood is pumped by the heart  Veins use the milking action of muscles to help move blood Figure 11.9 26 EDU2HBS Human Body Systems Capillary Beds  Capillary beds consist of two types of vessels 1. Vascular shunt – directly connects an arteriole to a venule 27 EDU2HBS Human Body Systems Capillary Beds 2. True capillaries – exchange vessels  Oxygen and nutrients cross to cells  Carbon dioxide and metabolic waste products cross into blood Figure 11.10 EDU2HBS Human Body Systems 28 Pulse  Monitored at “pressure points” where pulse is easily palpated 29 EDU2HBS Human Body Systems Blood Pressure  Pressure in blood vessels decreases as the distance away from the heart increases 30 EDU2HBS Human Body Systems Blood Pressure: Effects of Factors  Neural factors  Autonomic nervous system adjustments (sympathetic division)  Renal factors  Regulation by altering blood volume  Renin – hormonal control 31 EDU2HBS Human Body Systems Blood Pressure: Effects of Factors  Temperature  Heat has a vasodilation effect  Cold has a vasoconstricting effect  Chemicals  Various substances can cause increases or decreases  Diet 32 EDU2HBS Human Body Systems Factors Determining Blood Pressure 33 EDU2HBS Human Body Systems Variations in Blood Pressure  Human normal range is variable  Normal  140–110 mm Hg systolic  80–75 mm Hg diastolic  Hypotension  Low systolic (below 110 mm HG)  Often associated with illness  Hypertension  High systolic (above 140 mm HG)  Can be dangerous if it is chronic EDU2HBS Human Body Systems 34