Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Biological Bases of Behavior. Page 1 PSYC 7150 Biological Bases of Behavior Syllabus Spring 2005 Course: Biological Bases of Behavior (PSYC 7150) Semester: Spring 2005 Meeting Times: Tuesday, 12:30-2:00; Thursday, 12:30-1:30. Location: Haley Center, 3218. Instructor: Christopher Newland, Ph.D. 110 Thach 844-6479 [email protected] Text Biological Psychology. Rosenzweig, Breedlove, and Watson. 4th Edition. (2005) Selected Readings to be made available Web Address: http://www.duc.auburn.edu/~newlamc/personal Overview and Course Objectives. This course will cover some of the many relationships between the brain and behavior. My goal is to introduce the material and prepare you to go further with it as the opportunities arise. We will cover the basic foundations and how they contribute to our understanding of specific systems (e.g., motor function, learning) or sets of problems (e.g., behavior disorders). I trust that you already know something about how behavior is established, maintained and organized. We will cover the structure of the nervous system, the different dimensions along which structure falls (e.g., physical, chemical), the function of different components of the central nervous system, motor systems, the fundamental units of the nervous system (the neuron and the synapse), and the neurobehavioral bases of selected behavior disorders. The text is an exceptionally clearly written one so I will rely on you to do much of the reading on your own. I have chosen a fairly simple text so that we can spend some time on supplementary readings. The readings have been selected because they identify an interesting new trend in the behavioral neurosciences or because they illustrate how research is conducted in this area. Once we have finished with some background material we begin with the readings. You must submit one question per reading by 12 NOON on the day before the class on which the reading is scheduled to be covered. Some of this is difficult material, especially the first time through (and we will go fast), but it is within reach. I advise you to come to class prepared and to resist mightily the temptation to procrastinate. Read the assignment once before class, perhaps in one sitting. The first reading need not be to memorize details but rather to get an overview of what is in the chapter. Keep up with the material as we go through it in class. Read the chapter before quizzes and that reading should be for detail. I advise that when reading the chapter the second time you pause at the end of each section and summarize it using words and complete sentences. Pretend you are teaching it to someone else and, using the correct terms and experiments, explain what was in the chapter. Biological Bases of Behavior. Page 2 By the end of the semester you should: o Be able to describe the major features of the brain and spinal cord. o Understand the action potential of neurons and the important events that take place in the synapse. o Understand how synaptic events contribute to our understanding of drugs and of some behavioral disorders. o Describe the major effector systems associated with movement. o Have an appreciation of how behavior and the other neurosciences jointly contribute to our understanding brain/behavior relationships. o Have an appreciation of behavior and the nervous system fit into the broader context offered by our understanding of evolution by natural selection. Evaluation. Your grade from this section will be an average taken from the four exams. There will be three in-class exams. The fourth "exam" will come from the questions and comments on the extra readings. To count a question must posted on WebCT on time (submitted by the day before the reading is covered) and quality (evidence of a thoughtful reading of the entire paper) as well as participation in class discussion of the readings Course Structure. The course (and quizzes) will be centered around the textbook and readings. Class time will be used partly to cover material from the textbook, especially material that might be difficult to get from the book alone. For this I will need your help in letting me know what parts of the book you find difficult. I also hope to use some class time to extend the discussion in the textbook either to cover a topic in a little more depth or to discuss a point raised by the authors. Academic Honesty. Cheating is theft and a betrayal of the good-faith required for higher education to function. It will not be tolerated but will be dealt with according to the policies established in the Tiger Cub. You are expected to do your own work on quizzes but, of course, you may study together for quizzes. Students with Disabilities. Students who need accommodations are asked to arrange a meeting during office hours the first week of classes, or as soon as possible if accommodations are needed immediately. If you have a conflict with my office hours, an alternate time can be arranged. To set up this meeting, please contact me by E-mail. Bring a copy of your Accommodation Memo and an Instructor Verification Form to the meeting. If you do not have an Accommodation Memo but need accommodations, make an appointment with The Program for Students with Disabilities, 1244 Haley Center, 844-2096 (V/TT). Biological Bases of Behavior. Page 3 PG 683: Biological Bases of Behavior Lecture Schedule: Spring, 2005 WEEK OF # TOPIC ASSIGNMENT. 10 Jan 1 Origins of Neuroscience, Consciousness, Reductionism. Chapter 1 Ethics of Animal research. TBA Neurons and Glia Chapter 2. 17 Jan 2 Neural Structure 24 Jan 3 Ion Channels, Resting Potential, Action Potential, Chapter 3 Neurotransmission. (Washington, Thurs) 31 Jan 4 Neurotransmission. Chapter 4 7 Feb 5 Evolution of Brain and Behavior. Chapter 6 Smart Crows, Drunken Mice [1, 2, 3] Development (Study Section, Thurs) Chapter 7 14 Feb 6 EXAM 1. Wednesday 17 Feb. 21 Feb 28 Feb 7 8 Autism [4, 5] Aging Chapter 7. Chemicals and the Pace of Aging [6] General Principles of Sensory Processing Chapter 8 Modification of Sensory Cortex [7, 8] 7 Mar 9 Vision (SOT, Tues) Chapter 10 14 Mar 10 Motor Control and Plasticity Chapter 11 Stroke Therapy [9, 10, 11] Homeostasis Chapter 13 21 Mar 11 [12, 13] 28 Mar 12 Spring Break. 4 Apr 13 EXAM 2. 11 Apr 14 Biological rhythms. Chapter 14 Schizophrenia and Depression Chapter 16 [14] 18 Apr 15 25 Apr 16 30 Apr 17 3-4 May 6 May Learning and Memory Chapter 17, 18 Mechanisms of respondent conditioning Cortex, Striatum, Choice, and Reinforcement. Influences over development/assessment of risk [15, 16] [17, 18] [19, 20, 21] Conceptual Issues in Reductionism. [22, 23] Reading Period FINAL EXAM FRIDAY, 6 MAY 2005 5:00-7:30, EXAM 3 Biological Bases of Behavior. Page 4 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. Wahlsten, D., Metten, P., Phillips, T. J., Boehm, S. L., 2nd, Burkhart-Kasch, S., Dorow, J., Doerksen, S., Downing, C., Fogarty, J., Rodd-Henricks, K., Hen, R., McKinnon, C. S., Merrill, C. M., Nolte, C., Schalomon, M., Schlumbohm, J. P., Sibert, J. R., Wenger, C. D., Dudek, B. C., & Crabbe, J. C. (2003). Different data from different labs: Lessons from studies of geneenvironment interaction. Journal of Neurobiology, 54(1), 283-311. Weir, A. A. S., Chappell, J., & Kacelnik, A. (2002). Shaping of hooks in new caledonian crows. Science, 297(5583), 981-. Emery, N. J., & Clayton, N. S. (2004). The mentality of crows: Convergent evolution of intelligence in corvids and apes. Science, 306(5703), 1903-1907. Rodier, P. M. (2002). Converging evidence for brain stem injury in autism. Development & Psychopathology, 14(3), 537-557. Rodier, P. M. (2004). 2003 warkany lecture: Autism as a birth defect.[see comment]. Birth Defects Research, 70(1), 1-6. Newland, M. C., & Rasmussen, E. B. (2003). Behavior in adulthood and during aging is affected by contaminant exposure in utero. Current Directions in Psychological Science, 12(6), 212-217. Blake, D. T., Byl, N. N., & Merzenich, M. M. (2002). Representation of the hand in the cerebral cortex. Behavioural Brain Research, 135(1-2), 179-184. Blake, D. T., Strata, F., Churchland, A. K., & Merzenich, M. M. (2002). Neural correlates of instrumental learning in primary auditory cortex. Proceedings of the National Academy of Sciences of the United States of America, 99(15), 10114-10119. Liepert, J., Bauder, H., Wolfgang, H. R., Miltner, W. H., Taub, E., & Weiller, C. (2000). Treatment-induced cortical reorganization after stroke in humans. Stroke, 31(6), 1210-1216. Taub, E., Crago, J. E., Burgio, L. D., Groomes, T. E., Cook, E. W., 3rd, DeLuca, S. C., & Miller, N. E. (1994). An operant approach to rehabilitation medicine: Overcoming learned nonuse by shaping. Journal of the Experimental Analysis of Behavior, 61(2), 281-293. Taub, E., & Uswatte, G. (2003). Constraint-induced movement therapy: Bridging from the primate laboratory to the stroke rehabilitation laboratory. Journal of Rehabilitation Medicine(41 Suppl), 34-40. Corwin, R. L., Woolverton, W. L., & Schuster, C. R. (1990). Effects of cholecystokinin, damphetamine and fenfluramine in rats trained to discriminate 3 from 22 hr of food deprivation. Journal of Pharmacology & Experimental Therapeutics, 253(2), 720-728. Salamone, J. D., Wisniecki, A., Carlson, B. B., & Correa, M. (2001). Nucleus accumbens dopamine depletions make animals highly sensitive to high fixed ratio requirements but do not impair primary food reinforcement. Neuroscience, 105(4), 863-870. Winterer, G., & Weinberger, D. R. (2004). Genes, dopamine and cortical signal-to-noise ratio in schizophrenia. Trends in Neurosciences, 27(11). Kandel, E. R. (2001). The molecular biology of memory storage: A dialog between genes and synapses. Bioscience Reports, 21(5), 565-611. Roberts, A. C., & Glanzman, D. L. (2003). Learning in aplysia: Looking at synaptic plasticity from both sides. Trends in Neurosciences, 26(12), 662-670. Schultz, W., Tremblay, L., & Hollerman, J. R. (2000). Reward processing in primate orbitofrontal cortex and basal ganglia. Cerebral Cortex, 10(3), 272-284. Schultz, W., Tremblay, L., & Hollerman, J. R. (2003). Changes in behavior-related neuronal activity in the straitum during learning. Trends in Neurosciences, 26(6), 321-328. Costa, L. G., Aschner, M., Vitalone, A., Syversen, T., & Soldin, O. P. (2004). Developmental neuropathology of environmental agents. Annual Review of Pharmacology & Toxicology, 44, 87-110. Biological Bases of Behavior. Page 5 20. 21. 22. 23. Rodier, P. M. (2004). Environmental causes of central nervous system maldevelopment. Pediatrics, 113(4 Suppl), 1076-1083. Weiss, B. (1988). Neurobehavioral toxicity as a basis for risk assessment. TIPS, 9, 59-62. Bennett, M. R., & Hacker, P. M. (2001). Perception and memory in neuroscience: A conceptual analysis. Progress in Neurobiology, 65(6), 499-543. Bennett, M. R., & Hacker, P. M. (2002). The motor system in neuroscience: A history and analysis of conceptual developments. Progress in Neurobiology, 67(1), 1-52.