* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Anatomy Block 5 Oral Quiz Review
Survey
Document related concepts
Transcript
Anatomy Block 5 Oral Quiz Review 3/3/2013 12:08:00 AM Teach or demonstrate the following: 1.) The four layers of the abdominal fascia 1. Superficial Fascia (Camper’s)=fatty, subcutaneous fascia 2. Membranous fascia (Scarpa’s) = deeper membranous fat 3. Deep Investing Fascia = ‘felt’ fascia that covers the abdominal muscles 4. Endoabdominal Fascia = fascia of the transversalis muscle Note: arcuate line differences 2.) The four muscles of the abdominal wall 1. Rectus abdominus a. Paired muscles that run vertically i. Origin – Pubis ii. Insertion – Costal cartilages 5-7, xiphoid process iii. Innervation – (T7-T12) segmental nerves iv. Action – Flexion of the lumbar spine 2. Transversus abdominus a. Muscle of the lateral & anterior abdomen b. Horizontal (transverse) fibers & deepest muscle layer i. Origins Iliac crest Inguinal ligament Thoracolumbar fascia Costal cartilages 7-12 ii. Insertions Xiphoid, linea alba Pubic crest & pectin pubis via conjoint tendon iii. Innervation Thoracoabdominal nn. (T6-T11) Subcostal nerve (T12) Iliohypogastric nerve (L1) Ilioinguinal nerve (L1) iv. Action – Compresses abdominal contents 3. External oblique a. Largest, most superficial abdominal muscle b. ‘Hands in pockets’ fiber direction i. Origin – Ribs 5-12 ii. Insertions Iliac crest Pubic tubercle Linea alba iii. Innervation Thoracoabdominal nn. (T7-T11) Subcoastal nerve (T12) iv. Action – contralateral rotation of the torso 4. Internal oblique a. Rotate your ‘hands in pockets’ 90° b. Inferior layer to external oblique i. Origin Inguinal ligament Iliac crest Thoracolumbar fascia ii. Insertions Linea alba Pectin pubis (via conjoint tendon) Ribs 10-12 iii. Innervation Thoracoabdominal nn. (T6-T11) Subcostal nerve (T12) Iliohypogastric nerve (L1) Ilioinguinal nerve (L1) iv. Action Compresses abdomen Unilateral contraction will rotate vertebral column ispilaterally 3.) The organization of the neurovascular bundles in the abdominal wall and relate these structures to back, flank and anterior abdominal wall pain. When considering pain of the lower back, flank, or anterior abdomen, one should know that the dermatomal map of the anterolateral abdomen is almost identical to the distribution of peripheral nerves. The spinal levels T7-T12 do not participate in plexus formation. The exception to this rule is at the L1 level (iliohypogastric & ilioinguinal). Here, the dermatome has two peripheral nerves and explains why a swift kick to Sam Sauce’s nuts will also elicit epigastric pain. Between the internal oblique and transversus abdominis muscles is a neurovascular plane, which corresponds with a similar plane in the intercostal spaces. In both regions, the plane lies between the middle and deepest layers of muscle. The neurovascular plane of the anterior abdominal wall contains nerves and arteries supplying anterolateral abdominal wall. In the anterior part of abdominal wall, nerves and vessels leave neurovascular plane and lie mostly in subcutaneous tissue (Moore’s 191). This photo is sort of helpful and sort of hilarious. 4.) Describe the four routes of the venous drainage of the anterior and posterior abdominal wall 1. Superior epigastric vein & branches of musculophrenic vein to the internal thoracic o to the subclavian 2. Inferior epigastric vein & deep circumflex iliac vein to the external iliac vessels 3. Superficial circumflex iliac vein & superficial epigastric vein to the femoral vein 4. Posterior intercostal vein of 11th intercostal space & anterior branches of the subcostal veins to the azygos/hemiazygos system 5.) The five umbilical peritoneal folds The peritoneal folds refer to the five, one unpaired and two paired, foldings in the anterior peritoneum (1) Median umbilical fold o overlies the median umbilical ligament extends from bladder’s apex to umbilicus (2) Medial umbilical folds o overlie the occluded remains of umbilical arteries (2) Lateral umbilical folds o overlie the inferior epigastric vessels o only fold that’s over a functioning adult structure o extends from the inguinal ring to the arcuate line o 6.) The borders of the inguinal canal and its contents; relate these structures to direct and indirect inguinal hernias and to focal and diffuse abdominal pain The inguinal canal passes obliquely through the lower abdominal wall, extending between the superficial and deep inguinal rings. The borders of the canal are Anterior: aponeurosis of external oblique, fleshy internal oblique Superior: Medial crus of ext obl., musculoaponeurotic arches of internal oblique & transverse abdominus, transversalis fascia Posterior: Transversalis fascia, conjoint tendon (medial), and deep inguinal ring (lateral) Inferior: Inguinal ligament, lacunar ligament (medial), iliopubic tract (lateral) Contents are Male o Spermatic cord Vas deferens Ilioinguinal nerve Genital branch of genitofemoral nerve Testicular arteries/veins Pampiniform plexus Lymph vessels Cremaster muscle Female o Round ligament of the uterus o Ilioinguinal nerve o Lymph vessels Direct hernia Passes directly through the abdominal wall (Hesselbach’s Δ) to the superficial inguinal ring, forming peritoneal sac o Linea semilunaris (lateral rectus border) o Inferior epigastric vessels o Inguinal ligament Due to muscular weakness or increased intrabdominal pressure More common in aging men Indirect Does not extend to scrotum hernia Traverses the superficial, deep inguinal rings Is within the covering of spermatic cord May descend into scrotum can be congenital, common in younger males 7.) The location of the kidney, adrenal gland, urinary pelvis and ureter on a human and on an abdominal plain film and relate these structures to the presentation of flank pain Along mid-clavicular line Left kidney: T12-L3 Right Kidney: T12.5-L3.5 Pelvis’: L1-L2 Adrenals: T11 The ureters emerge ~L2 and descend in parallel (approx. linea semilunaris) and hit the bladder, which is midline, just superior to the pubis and inguinal ligaments. On abdominal plain film: P – renal pelvis * - ureter B – bladder Adrenals – unmarked K - kidney Week 32 3/3/2013 12:08:00 AM 1. The distinction between parietal and visceral peritoneum and explain their sensitivity to pain. Parietal peritoneum lines the abdominal wall and is external to the visceral peritoneum, which invests the viscera. The parietal peritoneum is extremely sensitive to pain and is innervated by the nerves involved with the local abdominal wall and diaphragm. Any injury or inflammation to the parietal peritoneum will present as an acute localized pain. The visceral peritoneum is not so sensitive and mainly carries sympathetic nerves to their appropriate viscera. However, pain receptors will fire on the visceral peritoneum if: Overdistension of hollow viscera (ie. Colon) Traction on the mesenteries which will stretch nerve plexi in the organ or mesentery Smooth muscle spasm Ischemia Injury to the visceral peritoneum presents as a dull, diffuse abdominal pain. 2. The concept of referred pain and to predict where in the body the pain of specific organ inflammation (dysfunction) will present clinically. Referred pain is simply the presentation of pain that reflects an injurious stimulus elsewhere, usually in the viscera. Note, this is not pain radiation. Referred pain happens when nerve fibers from regions of high sensory input (such as the skin) and nerve fibers from regions of normally low sensory input (such as the internal organs) happen to converge on the same levels of the spinal cord. The best known example is pain experienced during a heart attack. Nerves from damaged heart tissue convey pain signals to spinal cord levels T1-T4 on the left side, which happen to be the same levels that receive sensation from the left side of the chest and part of the left arm. A popular theory suggests that because the brain isn't used to receiving such strong signals from the heart, so it interprets them as pain in the chest and left arm. Following the concept of spinal levels illustrated above, think about shoulder pain. C3-C4-C5 keeps you alive right? The phrenic nerve is responsible for relaying any injury or inflammation of the thoracic diaphragm and shares spinal roots with the supraclavicular nerves (C3, C4), thus, diaphragmatic irritation may present as shoulder pain. Because I don’t have a great understanding of the innervation of the abdominal organs yet, I’m going to let this image from Moore’s pick up the slack. 3. Trace or follow the surfaces of the parietal and visceral peritoneum and their various interconnecting ligaments throughout the peritoneal cavity and predict to drainage locations for excessive fluids (ascites) in the supine patient. As detailed above, the parietal peritoneum lines the abdominal cavity. The visceral peritoneum invests the abdominal viscera and whose invaginations develop into peritoneal ligaments that hold the viscera in place and whose double-layered structures allows the passaging of neurovasculature to the appropriate organ. Continuities and connections between the parietal and visceral peritoneum exists where the gut tube exits and enters the abdominal cavity. Mesentery is a term for a double layer of peritoneum, both parietal and visceral. Usually connecting an organ to the abdominal wall. Anything with ‘meso-‘ mesentery. Note there is a mesoesophagus, mesogastrium & mesoappendix, aside from the mesocolons. See omentums in #4, similar structures. Peritoneal ligaments are double layered (visceral?) peritoneum that connects organs to each other, or to the abdominal wall. They are named, typically, after what they connect. The liver is connected by the: Falciform ligament – to the anterior abdominal wall Coronary ligament (3 parts) connect to inferior diaphragmatic surface o Right triangular o Left triangular (continuous with falciform) o Hepatorenal ligament – from lower posterior liver to the right kidney, forms right margin of the epiploic foramen Hepatogastric ligament – to the membranous portion of the lesser omentum Hepatoduodenal ligament – to the duodenum via the free, thickened edge of the lesser omentum The stomach is connected by the: Gastrophrenic ligament – to the inferior diaphragmatic surface Gastrosplenic ligament – to the splenic hilum Gastrocolic ligament – to the transverse colon via the greater omentum, saggy gross part The spleen is connected by the: Others Gastrosplenic ligament (above) Splenorenal ligament – to the left kidney Phrenicocolic ligament o Left hepatic flexure of transverse colon to the diaphragm Phrenicoesophageal ligament o Distal esophagus to the inferior diaphragm Ascites: would collect in hepatorenal and rectouterine recesses in the supine patient. 4. The distinction between greater and lesser omental sac and between the greater and lesser omentum The greater omental sac is synonymous with the general abdominal cavity. This includes everything inside the peritoneum, except the lesser sac. The lesser omental sac is formed by the greater and lesser omentum(s). It is connected with the greater sac at one point, known as the Foramen of Winslow or the epiploic foramen, which is generally proximal to the stomach. The margins of the sac are: Anteriorly by quadrate lobe of liver Left lateral margin by left kidney/adrenal Right lateral margin by epiploic foramen & lesser omentum Behind the stomach, front of pancreas The greater omentum is a large 4-layered fold of visceral peritoneum that hangs inferiorly from the greater curvature of the stomach, passing over the small intestines, before it reflects upon itself and ascends to the transverse colon before reaching the posterior abdominal wall. The lesser omentum is a double layer of visceral peritoneum that extends from the liver to the lesser curvature of the stomach and the origin of the duodenum. 5. Delineate the location of the esophagus, stomach, and duodenum and describe their surrounding relationships with the structures of the peritoneal cavity and the posterior body wall The esophagus is about 27cm long and runs from the pharynx to the cardia of the stomach. Posterior posterior abdominal wall, thoracic duct at T5, and descending aorta. Anterior trachea until T4/5, left bronchus, left atrium, and diaphragm Left lateral thoracic duct, aorta, left subclavian artery and left lung Right lateral right lung, azygos vein (better approach side for esophageal surgery) The stomach Posterior Lesser sac, pancreas, transverse mesocolon, transverse colon, left kidney/adrenal, spleen & splenic artery Anterior Anterior abdominal wall, left costal margin, diaphragm, & left lobe of liver Superior Left dome of diaphragm The duodenum is about 25cm long and has four regions (see dotted line on image below) a. First (5cm) Anterior liver & gallbladder, peritoneum Posterior Bile duct, gastroduodenal artery, portal vein, IVC Superior Epiploic foramen, neck of gallbladder Inferior Pancreas Medial pylorus b. Second (8cm) descending Anterior gallbladder, hepatic flexure Posterior right kidney/hilum, psoas major Medial pancreas, pancreatic duct Superior Superior duodenum Inferior inferior duodenum Laterial Ascending colon (10cm) Anterior small bowel mesentery, superior mesenteric a/v Posterior right psoas, IVC, aorta Superior head, uncinate process of pancreas, superior mesenteric c. Third vessels Inferior ileum d. Fourth (2.5cm) ascending Anterior beginning of root of mesentery, jejunum Posterior left psoas, left margin of aorta Medial Superior mesenteric a/v, uncinate of pancreas Superior Body of pancreas Inferior coils of jejunum 6. Trace the blood supply, innervation and lymphatic drainage of the esophagus, stomach, and duodenum Esophagus Arterial blood supply o Neck: inferior thyroid artery o Thorax: branches from thoracic aorta o Abdomen: branches from left gastric artery Venous drainage o Neck: inferior thyroid vein brachiocephalics o Thorax: Azygos, hemiazygos systems o Abdomen: left gastric vein portal vein Innervation o Sympathetic: greater splanchnic nerve (T6-T9) & periarterial plexuses via left gastric and inferior phrenic arteries o Parasympathetic: Esophageal plexus, (by vagal trunks forming anterior and posterior gastric branches) o Enteric Myenteric neurons Between longitudinal and circular muscle layers Submucosal neurons Deep to the muscularis mucosae Interneurons Ascend/descend between the above on vertical axis Lymphatic drainage o Neck: deep cervical lymph nodes to thoracic duct o Thorax: superior and posterior mediastinal nodes to thoracic duct o Abdomen: follows left gastric vein to celiac & gastric nodes to the intestinal lymphatics trunks to the cisterna chyli Stomach Arterial blood supply (celiac trunk) o Left gastric artery to left aspect of lesser curvature o From splenic short gastric & left gastroepiploic Usually a pair of short gastric arteries to the fundus Left gastroepiploic to the left aspect of greater curvature of stomach Anastomosis with right gastroepiploic artery o From common hepatic artery Hepatic artery right gastric artery to the right aspect of the lesser curvature Gastroduodenal artery right gastroepiploic artery to the right aspect of the greater curvature of the stomach Venous drainage o Right & left gastric veins portal vein o Right gastroepiploic superior mesenteric vein portal o Left gastroepiploic splenic portal o Short gastric splenic portal Innervation o Sympathetic: greater splanchnic nerve (T6-T9) via celiac plexus o Parasympathetic: Anterior vagal trunk: anterior gastric branches Posterior vagal trunk: anterior and posterior gastric branches o Enteric Myenteric neurons Between longitudinal and circular muscle layers Submucosal neurons Deep to the muscularis mucosae Interneurons Ascend/descend between the above on vertical axis Lymphatic drainage o All the following are nodes that drain into the celiac intestinal trunks to the cisterna chyli Superior gastric nodes Inferior gastric nodes Pacreaticolienal nodes Paracardial nodes Subpyloric nodes Duodenum Arterial blood supply o Gastroduodenal superior pancreaticoduodenal artery Splits anterior/posterior, supplying the anterior aspects of pancreas & duodenum and the posterior aspects o The above anastamose with the branches from the inferior pancreaticoduodenal artery, which at that point, demarcates the border between the foregut and the midgut, as the IPDA is a branch off the superior mesenteric artery Venous drainage o Posterior and anterior pancreaticoduodenal veins which reach the portal vein via the superior mesenteric vein & splenic vein Innervation o Sympathetic: greater and lesser splanchnic nerves (T5-T11) via the celiac and superior mesenteric plexuses and via periarterial plexuses on the pancreaticoduodenal arteries o Parasympathetic: anterior and posterior vagal trunks Lymphatic drainage o Anterior aspects of the duodenum drains to pyloric nodes o Posterior aspects drain to the superior mesenteric nodes Both of the above drain to the celiac nodes 7. Delineate the location of the liver, gall bladder, spleen and pancreas and describe their surrounding relationships with the structures of the peritoneal cavity and the posterior body wall The liver mainly occupies the upper right quadrant, below ribs 6-10, and on the left 6-7 costal cartilages. It has 4 lobes, 2 major, and major three surfaces. Superior involves both right & left lobes, convex, which fits under the vault of the diaphragm, which encompasses that entire surface Inferior uneven, multiple concavities, directed inferoposteriorly o Gastric impression major fossa formed by the stomach under the left lobe o Duodenal impression just posterior to gallbladder fossa and anterior to the renal impression o Renal impression posterior fossa under the right lobe o Colic impression anterior fossa formed by the right colic flexure o Gallbladder fossa formed by ________ (fill-in) Posterior rounded and broad on right lobe, narrow on left o There is a portion not covered in peritoneum, is directly attached to the thoracic diaphragm, marked by the coronary ligaments o The posterior right lobe and caudate lobe ‘wrap’ a portion of the IVC Gall Bladder Anterior anterior abdominal wall & inferior surface of liver Posterior Transverse colon; 1st & 2nd parts of duodenum Spleen (left side ) Superior diaphragm Posterior left kidney Anterior Stomach Inferoanterior transverse colon Medial lesser sac, pancreas, splenic hilum Pancreas Head o o o Body o o Anterior transverse colon Right lateral duodenum (spooning) Posterior IVC, common bile duct, aorta, renal veins, Anterior stomach (separated by omental bursa) Posterior Abdominal aorta, splenic vein, left kidney and associated vessels, origin of superior mesenteric artery o Inferior duodenojejunal flexure & left colic flexure Tail o Extends to the gastric surface of spleen to the phrenicosplenic ligament and contacts the left colic flexure 8. Trace the blood supply, innervation and lymphatic drainage of the liver, gall bladder, spleen and pancreas Liver Blood supply o Arterial: from common hepatic hepatic artery Left hepatic artery to the left lobe Right hepatic artery to the right lobe o Portal: from the portal vein, the liver derives nearly 50% of its oxygen supply Venous drainage o The hepatic veins carry de-oxygenated blood from the liver and blood cleaned by the liver from the portal circulation to the inferior vena cava Note: no valves on these veins and the derive from the ‘central vein’ from histology Innervation (via hepatic plexus, a derivative of the celiac plexus) o Sympathetic: Greater and lesser splanchnic nerves (T6-T11) o Parasympathetic: anterior and posterior vagal trunks Lymphatic drainage o All lymphatic vessels of the liver lead to the celiac nodes Remember these drain to the intestinal lymph trunks to the cisterna chili Gall Bladder Arterial blood supply o Celiac trunk right hepatic cystic artery Most common arrangement (~70%) Venous drainage o The cystic vein doesn’t have to travel far to dump its blood into the right branch of portal vein Innervation (via celiac plexus) o Sympathetic: greater & lesser splanchnic nerves o Parasympathetic: anterior and posterior vagal trunks Causes contractions (peristalsis) of gall bladder Lymphatics o To hepatic lymph nodes that send efferents to the celiac nodes cisterna chili Spleen Arterial Blood Supply o Celiac trunk splenic splenic hilum Venous drainage o Splenic vein joins the superior mesenteric vein to form the hepatic portal vein Innervation (via celiac plexus) o Sympathetic: Greater and lesser splanchnic nerves (T6-T11) o Parasympathetic: anterior and posterior vagal trunks Lymphatic drainage o Into pancreaticosplenic nodes, pyloric nodes, which join the intestinal trunks to the cisterna chili Pancreas Arterial Blood Supply o From gastroduodenal superior pancreaticoduodenal artery Splits anterior/posterior, supplying the anterior aspects of pancreas & duodenum and the posterior aspects o The SPDA anastamoses with the branches from the inferior pancreaticoduodenal artery, which at that point, demarcates the border between the foregut and the midgut, as the IPDA is a branch off the superior mesenteric artery o From the splenic artery dorsal artery to pancreas Venous drainage o The superior pancreaticoduodenal veins join with the portal vein o The inferior pancreaticoduodenal veins join with the jejunal veins superior mesenteric portal Innervation (celiac and superior mesenteric plexuses) o Sympathetic: Greater and lesser splanchnic nerves (T6-T11) o Parasympathetic: anterior and posterior vagal trunks Positive secretomotor function Lymphatic drainage o Pancreaticoduodenal nodes to the intestinal trunks to the cisterna chyli Week 34: Welcome Back 3/3/2013 12:08:00 AM Demonstrate the blood supply, innervation and lymphatic drainage of the jejunum and the ilium. Note: There’s barely any difference between these answers (jejunum & ilium) other than anatomic location and the arterial characteristics Jejunum Arterial blood supply o Abdominal aorta Superior mesenteric artery jejunal branches o Branches form loops with each other termed arterial arcades and send vertical branches (vasa recta) directly to the intestinal parenchyme Jejunal branches have long vasa recta Venous drainage o The superior mesenteric vein drains the jejunum (and ilium) --> becomes portal vein Innervation (by extension along superior mesenteric vessels) o Superior mesenteric plexus Sympathetic: Greater & lesser splanchnic nerves (T8T10) Parasympathetic: posterior vagus n. via celiac plexus o Enteric Myenteric neurons Between longitudinal and circular muscle layers Submucosal neurons Deep to the muscularis mucosae Interneurons Ascend/descend between the above on vertical axis Lymphatic drainage o Lacteals, blind-ended lymphatic spaces within intestinal villi, absorb fat from the lumen and deliver it to three groups of nodes, in sequential order Juxtaintestinal: right next to the intestinal wall Mesenteric: scattered among arcades Superior central: located by the proximal superior mesenteric artery Ilium Arterial Blood Supply o Abdominal aorta superior mesenteric artery ileal branches o Branches form loops called arterial arcades and send vertical vasa recta to the intestinal parenchyme Vasa recta are short compared to jejunum Venous Drainage o The superior mesenteric vein drains the jejunum (and ilium) --> becomes portal vein Innervation o Superior mesenteric plexus Sympathetic: Greater & lesser splanchnic nerves (T8T10) Parasympathetic: posterior vagus n. via celiac plexus o Enteric Myenteric neurons Between longitudinal and circular muscle layers Submucosal neurons Deep to the muscularis mucosae Interneurons Ascend/descend between the above on vertical axis Lymphatic Drainage o Lacteals, blind-ended lymphatic spaces within intestinal villi, absorb fat from the lumen and deliver it to three groups of nodes, in sequential order Juxtaintestinal: right next to the intestinal wall Mesenteric: scattered among arcades Superior central: located by the proximal superior mesenteric artery Demonstrate the blood supply, innervation and lymphatic drainage of the ascending, transverse and descending colon and rectum. Ascending Colon Arterial Blood Supply o Abd aorta SMA ileocolic artery & right colic artery o These anastamose with each other AND the middle colic artery, forming the marginal artery Venous Drainage o Ileocolic & right colic veins Superior mesenteric vein portal vein Innervation o Sympathetic: lesser splanchnic nerve (T10) o Parasympathetic: posterior vagus via superior mesenteric plexus Lymphatic Drainage o From paracolic & epicolic lymph nodes ileocolic & intermediate right colic nodes superior mesenteric nodes Transverse Colon Arterial Blood Supply o AA SMA middle colic artery, with small contributions from the right and left colic arteries via marginal anastamoses Venous Drainage o Middle colic vein SMV portal vein Innervation (both via superior mesenteric plexus) o Sympathetic: lesser splanchnic nerve (T11) o Parasympathetic: posterior vagal trunk Lymphatic Drainage o Middle colic lymph nodes SM nodes Descending (& Sigmoid) Arterial Blood Supply o AA IMA left colic and sigmoid arteries o Marginal artery also contributes via anastamosis Venous Drainage o Inferior mesenteric vein splenic portal Innervation o Sympathetic: lumbar splanchnic nn, superior mesenteric plexus, and IMA periarterial branches o Parasympathetic: Pelvic splanchnic nn via the inferior hypogastric plexus Lymphatic Drainage o Epicolic & paracolic nodes intermediate colic nodes inferior mesenteric nodes Rectum Arterial Blood Supply o Superior rectal artery (from IMA) o Right and left middle rectal arteries (from anterior divisions of common iliac arteries) o Inferior rectal artery (from internal pudendal arteries from internal iliac artery) Note: inferior & superior anastamose, tho rarely do they anastamose with the middle rectals Venous Drainage o Via superior, middle and inferior rectal veins Note: portal meets systemic via anastomoses Hemorrhoids! Innervation o Sympathetic: lumbar splanchnic nn., periarterial plexuses of IMA & superior rectal arteries o Parasympathetic: pelvic splanchnic nerves (S2-S4) via the left and right inferior hypogastric plexuses o Motor: pudendal (S2-S4) external anal sphincter o Somatic afferents: inferior anal (rectal) nerve (S2-S4) Lymphatic Drainage o Superior ½ rectum: Sacral nodes pararectal nodes inferior mesenteric nodes caval nodes o Inferior ½ rectum: sacral nodes internal iliac nodes Use embryological events to explain the adult morphology of the pancreas and use its adult structure to explain the dire consequences of most pancreatic diseases. At the septum transversum, one dorsal and one ventral bud form from the duodenum, each with their own common duct. As the small intestine develops, the smaller ventral bud, which begins as a branch of the future common bile duct, connecting the liver and gall bladder to the duodenum, swings around to the dorsal side. The dorsal bud, which has a direct connection of its own to the duodenum, remains put. The ventral bud joins the dorsal around the sixth week. The ventral duct will give rise to the pancreatic duct and the dorsal duct will become the accessory pancreatic duct. Usually, this accessory duct joins the main duct to empty into the common bile duct. However, sometimes the accessory duct’s opening to the duodenum remains patent and will empty directly into the duodenum via the minor duodenal papilla. The adult structure of the pancreas has a single output of pancreatic juice. Any structural blockage or stricture of drainage vessels is likely to cause damage because of the specific contents (zymogens) of the pancreatic juice becoming activated and causing self-digestion. Note that blockage at the ampulla of Vater, due to gallstone etc…, will also block bile drainage to the duodenum and will back up into the pancreas, activating digestive juices. Compare and contrast the flow of bile from the flow of pancreatic juices through the biliary tree into the duodenum. Pancreatic juices first begin at the exocrine acinus. There, acinar cells secrete digestive zymogens into the acinar lumen, which is collected through a series of intercalated ducts that eventually join the pancreatic duct (or accessory pancreatic duct.) In those ducts, water and bicarbonate are secreted in large amounts that add significant volume and dilute the pancreatic juice. The pancreatic duct joins the common bile duct just proximal to the ampulla of Vater, and together, perforate the duodenum at the major duodenal papilla. Bile begins in the liver. From hepatocyte to the bile canaliculi, the bile flow from small intrahepatic ducts to extraheptic ducts that join the cystic duct to form the common bile duct. Note, the biliary duct epithelium also secretes a large volume of water and bicarbonate to the bile. The common bile duct, as above, joins the pancreatic duct and, together, they drain their contents into the descending duodenum at the major duodenal papilla. Compare and contrast the role of the small bowel in digestion to that of the large bowel. The small bowel, from duodenum to ilium, is responsible for the body’s chemical digestion of protein, fat, and certain carbohydrates. The large intestine does not produce digestive enzymes and serves mostly an absorptive and poo-forming function. However, a small amount of digestion does occur on complex plants starches that remain undigested by our endogenous amylases, etc. The digestion that does occur is by gut flora which possess digestive enzymes we do not. The resultant products (acetate, propionate, butyrate) are absorbed at the large colon as well and provide a small caloric input daily. Use vertebral levels to relate the pancreas, duodenum, kidneys and spleen to each other on an abdominal plain film. Vertebral levels Pancreatic Body – L2 Duodenum Part 1 – L1 Part 2 – L2 L3 Part 3 – L3 Part 4 – L3/L2 Kidneys – T12 L3 Right kidney slightly lower than left Spleen – T7/T8 T11 Week 35 3/3/2013 12:08:00 AM Demonstrate the blood supply to the organs of the celiac artery territory Liver Celiac trunk common hepatic a. hepatic a. r & l hepatic aa. Gall Bladder Celiac trunk common hepatic a. hepatic a. r. hepatic a. cystic artery Stomach Celiac trunk left gastric a. left aspect of lesser curvature Celiac trunk common hepatic a. hepatic a. right gastric a. right aspect of the lesser curvature Celiac trunk splenic a. left gastro-omental a. left aspect of greater curvature Celiac trunk common hepatic a. gastroduodenal a. right gastro-omental a right aspect of greater curvature Celiac trunk splenic a. short gastric & posterior gastric aa. Esophagus Celiac trunk left gastric a. esophageal branch abdominal esophagus Spleen Celiac trunk splenic a splenic hilum Superior duodenum Celiac trunk common hepatic a. gastroduodenal a. superior pancreaticoduodenal a. anterior and posterior branches Superior pancreas Celiac trunk common hepatic a. gastroduodenal a. superior pancreaticoduodenal a. anterior and posterior branches Demonstrate the blood supply to the organs of the superior and inferior mesenteric artery territories. Inferior duodenum & pancreas SMA inferior pancreaticoduodenal aa. anterior & posterior branches Jejunum & ileum SMA jejunal branches o Branches form loops with each other termed arterial arcades and send vertical branches (vasa recta) directly to the intestinal parenchyme o Jejunal branches have long vasa recta SMA ileal branches o Branches form loops called arterial arcades and send vertical vasa recta to the intestinal parenchyme o Vasa recta are short compared to jejunum Cecum & Ascending Colon SMA ileocolic a & right colic a. Transverse Colon SMA middle colic artery & marginal artery Descending Colon IMA left colic & marginal artery Sigmoid Colon IMA sigmoid arteries Rectum Superior: IMA superior rectal artery Middle & inferior from common & internal iliac arteries Demonstrate the clinical presentation of portal hypertension a) due to liver failure; b) due to occlusion of the portal vein proximal to the splenic vein A) Liver failure will cause portal hypertension that can manifest in multiple, and usually, in all of the following presentations: Esophageal varices (via left gastric vein backup) Hemorrhoids (via inferior mesenteric veins) Caput medusa (via occluded umbilical veins) Ascites B) Portal occlusion (at juncture of splenic/SMV, before the umbilical and left gastric veins empty into portal system) Milder ascites Hemorrhoids For next three parts, I give you Jack Greater splanchnic nerve: T6-T9 Lesser splanchnic nerve: T10-T11 Least splanchnic nerve: T12 Generally, this is the schpeal for each of the next three questions. At each spinal nerve, you have visceral and somatic afferents. With chronic stimulation of the visceral components, that impulse will spill over and stimulate the somatic nerve at that spinal level and cause the sensation of pain. In the anterior abdominal wall, we use four quadrants to navigate the clinical presentation of abdominal pain and the spinal levels of each quadrant’s underlying viscera to create a differential. Use the innervation of the celiac organs to diagnose upper right or left quadrant pain patterns The celiac plexus provides sympathetics from the greater and lesser splanchnic nerves, which are T6-T11. Note, T11 is a small contribution here. LUQ – spleen, pancreas, pancreatic duct, stomach, esophagus RUQ – liver, gall bladder, pancreas, pylorus Use the innervation of the superior mesenteric organs to diagnose periumbilical pain patterns and lower right quadrant pain patterns The superior mesenteric organs (midgut) receive visceral input from all three thoracic splanchnic nerves, which means that T6-T12 are involved here. Periumbilical – small bowel mesentery, pancreas, appendix, distal stomach LRQ – appendix, cecum, ascending colon, ileum Use the innervation of the inferior mesenteric organs to diagnose lower left quadrant pain patterns The inferior mesenteric organs receive sympathetic input from the lumbar splanchnic nerves, which are L1 & L2, via the inferior mesenteric plexus. Also, parasympathetics now originate from the pelvic splanchnic nerves (S2S4). LLQ: Transverse, descending, sigmoid colon, rectum, mesentery