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memory & attention Modular Operant Box for Operant Conditioning Modular Operant Behavior System Our Modular Operant Chamber is an entirely modular experimental enclosure designed to conduct operant conditioning procedures (e.g. food reinforcement, DMTS, conflict tests, self-administration, etc). The operant chamber is made in an entirely modular structure which allows complete disassembling or rearrangement to build a new space of different dimensions/components or to enable storage in the minimum space. It can be easily transformed from rat chamber to mice chamber (or vice versa) with a reduced cost. A frontal door offers a total accessibility inside the chamber. Walls and cover can be of different material or color, since they are totally removable. Each chamber is associated with a Link Box which provides power to up to 8 (expandable to 16) Operant Modules (levers, lights, sound, dispensers, electrical shock) conferring to the chambers a full autonomy. Special accessories are provided for self-administration procedures. Only one cable connects the Link Box to the LE85XCT Programmer or PC (PackWin Software), this last for advanced protocol configuration and running. The Cages can be equipped with a weigh transducer in order to record activity or freezing. Key Features • Entirely modular system • Easily transformed between rat and mice chamber • Reduced number of cables • Possibility of customization • Up to 8 stations can be connected at once to PC through a single cable Parameters Measured • Number of responses (LE 85XCT) • Number of reinforcements (LE 85XCT) • Many user-defined parameters (see PackWin software) Specifications Base Dimensions 440 (W) x 360 (D) x 35 (H) mm Working Area (Mouse) 200 (W) x 200 (D) x 250 (H) mm Working Area (Rat) 250 (W) x 250 (D) x 250 (H) mm Material Composition Stainless steel, aluminum and methacrylate Power Supply 110V/220V, 50/60Hz Maximum Number 8 stations connected to a PC of Stations (When Working with PC) Connection of Several Units to PC No need of PC interfaces! Direct connection through one cable! Certifications CE compliant Components Included • Operant Chamber (mice or rat) • Instruction manual • Cables and connectors • 2 year warranty Options • Link Box (power connection box for up to 8 modules) • Wide range of modules • Sound attenuating box • MPS push button • Experiment progamation unit (with ratio and interval schedules and shocker) • PackWin software 40 Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com Panlab | Harvard Apparatus • Spain +34934190709 • international +34834750697 • fax +34934750699 • www.panlab.com memory & attention Modular Operant Box for Operant Conditioning (continued) Model Product LE1002CP Operant Chamber Setup for Mice BH1 76-0146 Including Pellets Dispenser, Lever, Light Stimuli, Mice Shock Grid and LINK BOX 01 Order # Price $ 4,680.00 LE1005CP Operant Chamber Setup for Rats Includes Pellets Dispenser, Lever, Light Stimuli, Rat Shock Grid and LINK BOX 01 BH1 76-0148 4,472.00 LE1002CL Operant Chamber Setup for Mice BH1 76-0147 Includes Drop Liquid Dispenser, Lever, Light Stimuli, Mice Shock Grid and LINK BOX 01 4,680.00 LE1005CL Operant Chamber Setup for Rats BH1 76-0149 Includes Drop Liquid Dispenser, Lever, Light Stimuli, Rat Shock Grid and LINK BOX 01 4,472.00 Contact Technical Support for the Broad List of Additional Modules for our Modular Operant Chambers! Options LE1002 Modular Mice Operant Chamber BH1 76-0151 2,028.00 LE1005 Modular Rats Operant Chamber BH1 76-0152 2,054.00 LE100201 Mice Shockable Grid BH1 76-0153 359.00 LE100501 Rats Shockable Grid BH1 76-0154 499.00 LE1050 MPS Push Button BH1 76-0155 307.00 LINKBOX01 Link & Power for up to 8 Modules BH1 76-0156 993.00 LE26 Sound Attenuating Box BH1 76-0157 2,236.00 LE85XCT PROGRAMMER with Ratio BH1 76-0158 & Interval Schedules and Shocker 4,108.00 LE10026 Shock Generator with Scrambler, 0 - 2 mA Output BH1 76-0159 1,612.00 PACKWIN PC software to Control up to 8 Operant Chambers BH1 76-0002 5,753.00 LE1010 Harness Set for Electrical Stimulation BH1 76-0160 749.00 LE12605 Electrical Stimulator BH1 76-0161 2,132.00 Pump 11 Plus BH1 70-2208 1,705.00 Citations Pellon R et al. (2007) Pharmacological analysis of the effects of benzodiazepines on punished schedule-induced polydipsia in rats. Behav. Pharmacol. 18(1): 81-87. (Punished scheduleinduced drinking, rats, Spain) Pérez-Padilla A, Pellón R (2006) Level of response supresión and amphetamine effects on negatively punished adjunctive licking. Behav. Pharmacol. 17(1): 43-49. (Punished scheduleinduced drinking, rats, Spain) Conejo NM et al. (2005) Brain metabolism after extended training in fear conditioning task. Psicothema. 17(4): 563-568 (disruption of lever pressing in fear conditioning task, Rat, Spain) Manrique T et al. (2005) Early learning failure impairs adult learning in rats. Dev. Pshychobiol. 46(4): 340-349. (Rat, Spain). Toro JM et al. (2005) Backward Speech and Speaker Variability in Language Discrimination by Rats. J. Exp. Psychol. 31(1): 95–100. (rat, Spain) Lopez-Moreno JA et al. (2004) Long-lasting increase of alcohol relapse by the cannabinoid receptor agonist WIN 55,212-2 during alcohol deprivation. J. Neurosci. 24(38): 8245-8252. (ethanol self-administration, rat, spain) Pérez-Padilla A, Pellón R (2003) Amphetamine increases schedule-induced drinking reduced by negative punishment procedures. Psychopharmacol. 167(2): 123-129. (Punished scheduleinduced drinking, rats, Spain) Burgal M et al. (1988) Asymmetric incorporation of [14C]cyanate and of fluorescein isothiocyanate in mamillary body of conditioned rats. Neurochem. Res. 13(5): 435-442. (learning, Rat) Cuomo V et al. (1983) Behavioral and biochemical effects in the adult rat after prolonged postnatal administration of haloperidol. Psychopharmacol. 81(3): 239-243. (Differential reinforcement of low rate schedule, rat, Italy) Cuomo V et al. (1981) Enduring behavioral and biochemical effects in the adult rat after prolonged postnatal administration of haloperidol. Psychopharmacol. 74(2): 166-169. (Differential reinforcement of low rate schedule, rat, Italy) Harvard Apparatus • phone 508.893.8999 • toll free U.S. 800.272.2775 • fax 508.429.5732 • www.harvardapparatus.com Panlab | Harvard Apparatus • Spain +34934190709 • international +34834750697 • fax +34934750699 • www.panlab.com 41