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Name ____________________________ Date ______________ Period ________ Biology Unit 3 – Infectious Disease, Background Paper 3-3 Viruses From the common cold to AIDS and Ebola, viruses affect every living thing on earth. Even plants are not immune to viral infections. The ironic thing is that viruses themselves are not alive. They do not belong to any of the six kingdoms of living organisms (Eubacteria, Archaebacteria, Protists, Fungi, Plants, & Virus Capsid Animals). They fall short of the ‘living’ designation since they do not metabolize energy, they Viruses attacking bacteria cannot reproduce on their own, and they do not grow. They consist simply of a strand of genetic information – either DNA or RNA – surrounded by a shell of protein called the capsid1. Although they can do few of the things we usually use to typify living organisms they are masters at one thing. They can hijack the mechanisms of living organisms to make viral copies of themselves. Viruses have evolved two different systems of cell invasion and hijacking. The first and fastest method is called the lytic cycle. You catch a cold and the virus injects its own DNA into your cell where the instructions encoded on that strand of DNA tell your cell to stop functioning normally and divert all future energy to the production and assembly of new viruses. Once your cell is packed with these viral copies it splits open and spills millions of viruses out to infect other cells. These cells then become mini factories for more viruses. The cycle continues until either your body’s defense systems identify and hunt down the viruses or you die. The second method, the lysogenic cycle, is slower but very effective. The virus injects its genetic code into your cell. Rather than take over your cells machinery the DNA splices itself into your DNA and remains inactive. Every time your infected cell makes a copy of itself it also makes a copy of the viral DNA. At some point in the future the viral DNA becomes active and ‘breaks out’ into the lytic cycle of infection described above. Instead of just a few cells producing viruses your body now has millions of cells with copies of the virus DNA ready to become virus factories. On the back of this reading draw the steps of infection of both the lyic and lysogenic cycles. Your best source will be a search for images on the internet. When the reading is returned cut out and paste the drawings into your journal. I found a good one at http://www.bio.miami.edu/~cmallery/150/gene/18x5.jpg 1 Images CC BY Graham Colm Background 3-3,Disease2012 Text 2012 Greg Ballog Page 1 Name ____________________________ Date ______________ Period ________ Title of Reading: 3-3 Viruses Points Earned 1 2 3 4 5 6 7 Virus Life Cycles (3 points) A) What one question do I have about this article? 1 Point A&B B) Show or describe the reading to a parent or guardian (Name ___________________). What comments or questions did they have concerning the reading? (Biology Homework Time __________) Background 3-3,Disease2012 Text 2012 Greg Ballog # 1 2 3 Answer Page 2