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HOW THE BODY DIGESTS FOOD Digestion is the body’s way of processing food into smaller molecules that it can use for energy and to get rid of waste. There are several steps in the digestion process as food passes through the body including ingestion, secretion, mixing, digestion, absorption, and excretion. Several organs and pathways (seen in Figure 1) participate in the digestion process both mechanically and chemically. By taking a closer look into the steps in the digestion process, we are better able to understand what goes on in our bodies when we eat food. Figure 1. Basic anatomy of the GI tract and organs involved in digestion.1 Ingestion Secretion The digestion process begins in the mouth where teeth start to chew up the food. Meanwhile, enzymes from the salivary glands help initiate the breakdown of food so that it is lubricated as it travels down through the pharynx and esophagus. Once the food is chewed up and traveling down the pharynx, it is called bolus. The esophagus carries the bolus past the esophageal sphincter and into the stomach. The sphincter’s function is to trap the food in the stomach so that it isn’t regurgitated back into the esophagus. There are sphincters (pyloric, ileocecal) that have the same function in other locations through the GI tract that will be discussed. Secretion starts the moment food enters the mouth. The body secrets several liters of fluids each day including saliva, mucus, hydrochloric acid, enzymes, and bile. All of these fluids play an important role in helping to break down food. Saliva contains an enzyme called salivary amylase, which lubricates the food and begins the digestion of carbohydrates. Mucus provides a protective barrier on the inside of the gastrointestinal tract as the bolus travels through, and hydrochloric acid from the stomach digests the food chemically while also killing any unnecessary bacteria. Enzymes help to disassemble large macromolecules into smaller molecules via chemical reactions. Lastly, bile assists in breaking down masses of lipids into tiny globules that can easily be digested. There are other fluids that are secreted by organs during the digestion process, like pancreatic juice, but the five mentioned are the major ones. Movement and Mixing Movement and mixing occurs in every pathway through the GI tract as the bolus travels down. The three methods the body uses to mix and move foods are swallowing, peristalsis, and segmentation. Swallowing is the process of taking in the food where the muscles work to move the food towards the stomach. Peristalsis is the wave-like movement that travels down the GI tract; it starts at the esophagus and works all the way down past the intestines to the end of the GI tract. Figure 2 is a simple representation of how the smooth and skeletal muscles move the bolus in a wave-like pattern. Finally, segmentation is short contractions that occur in the small intestine to help increase absorption of nutrients and mixing of fluids. Swallowing, peristalsis, and segmentation are all vital steps in the mixing and movement portion of the digestion process. Figure 2. Demonstration of peristalsis.2 Digestion Digestion transforms the food into basic compounds that will be used by the body or stored for future energy. Small particles of food can be broken down into both major and minor nutrients. Major nutrients include macronutrients, which must be broken down enzymatically, and minor nutrients including carbohydrates, proteins, and lipids. There are two types of digestion, mechanical and chemical (Figure 3), and both contribute equally to the breakdown of food. Mechanical digestion begins with the teeth chewing food and then continues with the mixing and movement of food, aided by contractions (segmentation). Chemical digestion occurs simultaneously with mechanical digestion through the help of the bile produced by the liver. Chemical digestion begins in the mouth as well, where the enzymes in saliva assist in breaking down carbohydrates. The enzymes and acid in the stomach contribute to this chemical breakdown, but most of the chemical digestion occurs in the small intestine where the pancreas secretes pancreatic juice. Carbohydrates, for example, will be broken down into monomers called monosaccharides. Through the combination of chemical and mechanical digestion, food will be successfully broken down into four components: amino acids, fatty acids, monosaccharides, and nucleotides. These four components are considered the basic “building blocks” that the body uses for energy. content of the interstitial cavity where the bile helps to further dissolve it into fatty acids or cholesterol. After crossing the mucosa, the small molecules are reformed into large molecules and then travel through vessels to be stored in different parts of the body. Finally, water and salts are absorbed by the small intestines and assimilation occurs, where nutrients are delivered to other cells in the body. Figure 4. Monosaccharides broken down into glucose molecules via chemical digestion.4 Figure 3. Examples of chemical and mechanical digestion in the stomach.3 Absorption Once broken down into the four building blocks, the body is ready to absorb the food. Absorption begins in the stomach with the help of the secreted fluids. In the walls of the small intestine, small blood and lymphatic vessels pick up the amino acids, fatty acids, monosaccharides, and nucleotides and carry them to the rest of the body. The large intestine participates in absorption by further absorbing water and vitamins. Absorbed materials cross the mucosa of the upper cavity of the small intestine into the blood, and are carried off to different parts of the body for storage or usage. As seen in Figure 4, monosaccharides are further broken down by enzymes into glucose molecules; the glucose molecules will then travel to the liver where they will be stored or used by the body for energy. Fats are dissolved into the watery Elimination Elimination is the final step in the digestion process. This step helps excrete waste from the body through a process called defecation. Defecation is controlled voluntarily by the brain so that the body eliminates indigestible substances, preventing them from accumulating inside the intestines. Solid wastes exit the body in the form of feces. The rectum allows for storage of the wastes until it is ready to exit the body, either voluntarily or involuntarily. Conclusion Through these five steps (ingestion, secretion, mixing and movement, digestion, absorption, and excretion) the body is able to process food for energy and get rid of wastes. Ingestion is the intake of food in the mouth, which ignites the body to start secreting different fluids like saliva, bile, acids, enzymes and mucus. These fluids help to break down the food into smaller molecules that can be easily digested. Mixing and movement then occurs within the pathways, followed by mechanical and chemical digestion. The body then absorbs the necessary nutrients it needs and uses is for energy or stores it somewhere else in the body. Finally, unnecessary wastes are excreted from the body. Image References 1.http://www.bing.com/images/search?q=ingestion+step+of+ digestion&view=detailv2&&id=2A2013AF799E542E94631 E996E8144261B53EC39&selectedIndex=3&ccid=IpF0YSp E&simid=607997478140709452&thid=OIP.M229174612a4 4334543d8e563c07953eco0&ajaxhist=0 2.http://www.bing.com/images/search?q=perastalsis&view=d etailv2&&id=5B9CA3F4F7A4772622BC98AD135AF5EAC CA61982&selectedIndex=48&ccid=tnA5touN&simid=6079 98599127043670&thid=OIP.Mb67039b68b8d7afd0b223045 f2c68784o0&ajaxhist=0 3.https://www.google.com/search?q=ingestion&espv=2&biw =1205&bih=757&site=webhp&source=lnms&tbm=isch&sa= X&ved=0CAYQ_AUoAWoVChMItOLe8uriyAIVQjoCh1fRQf#tbm=isch&q=chemical+digestion&imgrc=xM5yYSHm4Px 2tM%3A 4.https://www.google.com/search?q=absorption+process&es pv=2&biw=1089&bih=712&source=lnms&tbm=isch&sa=X &ved=0CAYQ_AUoAWoVChMIp4rD1sDWyAIVCVUCh0vqgGc#tbm=isch&q=break+down+of+carbohydrates&i mgrc=_n9jGZjYBqICHM%3A