Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Cell culture wikipedia , lookup
Embryonic stem cell wikipedia , lookup
Cell theory wikipedia , lookup
Organ-on-a-chip wikipedia , lookup
Microbial cooperation wikipedia , lookup
State switching wikipedia , lookup
Induced pluripotent stem cell wikipedia , lookup
Human embryogenesis wikipedia , lookup
Adoptive cell transfer wikipedia , lookup
Hematopoietic stem cell wikipedia , lookup
Artificial heart wikipedia , lookup
WEBQUEST THE HEART Student Pages Designers Brianne Miller, Molly Bugaile 1 The Heart T he heart is the most important muscle in the human body because it pumps blood all throughout the body, allowing other organs to function properly. The blood delivers oxygen and nutrients to the brain, muscles, bones and organs. T he heart acts like a pump! Before each beat, the heart fills with blood. Then it contracts (squeezes) to squirt blood into the blood vessels all through the body. The heart is made of millions of special long muscle cells, called cardiomyocyte cells. The contraction (tightening) of these cells causes the heart to beat. The contractions are controlled by electrical signals that pass from cell to cell. How neat! T he right side of the heart (atrium and ventricle) receives blood from the body and pumps it into the lungs. The left side of the heart does the exact opposite: it receives blood from the lungs and pumps it out to The heart is a powerful muscle! the body. The heart does this all day and all night, every day. The heart is one hard worker! W hen a heart attack occurs, heart tissue dies. The body cannot make new heart muscle tissue on its own. Instead it makes scar tissue which is a more disorganized tissue, and weakens the heart! R egenerative medicine helps an injured body heal faster by enhancing the body’s natural healing process. Many treatments will use stem cells that can be found in the center of the bone - the bone marrow. These stem cells are capable of becoming new blood, bone or heart cells. Ready to learn more about the heart? H ow does regenerative medicine help the heart? In the laboratory, stem cells from the bone marrow are exposed to growth factors. Growth factors are proteins that help the stem cells grow and stay healthy until they are put back in the body. In the laboratory, the stem cells multiply and grow to become new heart cells. These new heart cells are then placed on a mesh patch (which is flexible) and in turn, the patch is placed on the heart. Eventually, the cells on the flexible patch grow into new heart cells and replace the damaged (or dead) cells. Over time, the patch is absorbed into the body. Because of regenerative medicine, the heart can continue beating normally! Tissue Engineering For Life: Teacher Guide. Version #3 Heart Module - Student Student Pages 2 Today we will go on a journey to explore regenerative medicine. Using the Internet as a resource tool, you will explore websites for details and find answers to questions about regenerative medicine. Through your own research, you will make new discoveries! Along the way, write down any key points or cool information you find. Later, we will share our results with the entire class. Now, get to work, but as always, enjoy the journey! my notes Heart Module - Student Task Process Using the Internet and a specific website as our guide, we will venture through the depths of regenerative medicine. How awesome! Through discovering and exploring the “Dr. Allevable’s Unbelievable Laboratory” website, you will follow directions given to complete the assigned task. Evaluation Once you have gained the necessary background information, you will demonstrate what you have learned about the heart and regenerative medicine to the class! This can include a poster about advances in regenerative medicine, a brochure, or even a flip book detailing a heart attack or the growth of young cells (stem cells). Once you decide on a product, share this idea with your teacher so he or she can record it. Remember, the project types listed are simply ideas. You can create whatever you want! Just be sure to check with your teacher for specific ideas he or she would like to see. Conclusion Carefully follow directions on the attached page. Please work quietly and do not disturb others. Be considerate of those around you. Do your best work and remember to always do your own work. Above all else, RESPECT others – for respect is essential in making our classroom successful. Instructions Part I: Regenerative Medicine 1. How long does it take for regenerative medicine advances to heal injuries? a). it’s longer than other healing processes b). it’s shorter than other healing processes c). there is no significance d). it’s more complicated 2. What does regenerate mean? _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ Tissue Engineering For Life: Teacher Guide. Version #3 3 _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ my notes Part II: The Heart Heart Module - Student 3. What is regenerative medicine? 1. Why is the heart the most important muscle in our body? _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 2. What is the job of the heart? a). it sends signals to other parts of the body b). it delivers nutrients to the organs c). it creates plaque in the arteries d). it pumps blood 3. What is the heart made of? a). cardiomyocyte cells b). stem cells c). plant cells d). B cells & T cells 4. What are cardiomyocyte cells? a). B cells & T cells b). cells that make up plants c). long muscle cells which enable the heart to beat d). cells that are in all our organs 5. How does the heart beat? Mark all TRUE statements. a). heart muscles squeeze together b). it makes noises (‘thud thud, thud thud’) c). by delivering oxygen to other parts of the body d). the contraction of cardiomyocyte cells, controlled by electrical signals 6. Draw the inside of the heart. Tissue Engineering For Life: Teacher Guide. Version #3 4 _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ my notes 8. What role does the septum play? _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ Heart Module - Student 7. What are the atria? _____________________________________________________________________ 5 Part III: Regenerative Medicine in the Heart 1. What is the main cause of heart tissue damage? _____________________________________________________________________ _____________________________________________________________________ 2. What is a heart attack? _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 3. What is the main cause of a heart attack? _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 4. Are any other parts of the body affected by a heart attack? _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 5. Why is the heart much weaker after a heart attack? _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ ______________ Tissue Engineering For Life: Teacher Guide. Version #3 my notes 6. Mark which statement or statements are TRUE. You can prevent heart attacks by: a). healthy diet and regular exercise b). seeing the doctor regularly c). smoking d.) watching TV Heart Module - Student _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 6 7. Can you think of some more healthy activities that help your heart? _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 8. What are stem cells? a). T cells and B cells b). plant cells c). young cells found in bone marrow d). cardiomyocyte cells 9. What characterizes a biological scaffold? Mark the TRUE statements. a). a biological scaffold lasts forever b). it looks just like the tissue it is trying to heal c). it provides support for new cells and new blood vessels d). it’s very hard and sturdy 10.Can you explain the new regenerative medicine treatment that is currently in development to heal injured hearts? _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ 11.What do you think the main goal of regenerative medicine is? _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ Tissue Engineering For Life: Teacher Guide. Version #3 Have time to spare? More Websites ◊◊ American Heart Association - http://www.americanheart.org/presenter.jhtml?identifier=1557. Check out this site! It’s a detailed description of how the heart works. Remember learning this? Jot down new notes and feel free to share them with those near you. For fun, feel free to quiz each other! How much does your classmate REALLY remember?! ◊◊ American Heart Association - Fitness http://www.americanheart.org/presenter.jhtml?identifier=1200013. Learn more about how important exercise and fitness is. Look for answers to the following questions: ◊◊ What are the best activities for your heart? ◊◊ What are some of the worst activities for your heart? ◊◊ What are Heart Walks and where is one nearest you? ◊◊ How can you get physical activity at home? ◊◊ What are some benefits of physical activity? Evaluation Choices Show your classmates and teacher(s) what you know! Create a visual presentation with images and writing that describes at least 6 things you learned about the heart and regenerative medicine. Cite any outside sources. Some ideas are listed below. ◊◊ An informative poster about new medical advances associated with regenerative medicine ◊◊ A brochure about the heart ◊◊ A flip book showing how the heart works ◊◊ Got another idea? Make sure to check with your teacher first! Have fun everyone! Tissue Engineering For Life: Teacher Guide. Version #3 Heart Module - Student my notes 7