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3D speckle tracking images Wen-Chung Yu, M.D., FESC Taipei Veterans General Hospital, National Yang-Ming University, Taipei, Taiwan Speckle tracking echocardiography makes it feasible to assess global and regional myocardial function. Recent studies support the role of speckle tracking echocardiography in analysis of left ventricular dyssynchrony, prediction the outcome of myocardial infarction and heart failure. However, acquisition and analysis of myocardial strain with 2D speckle tracking is relative time consuming and it may limit its clinical application. With the rapid advance in the field of 3D echocardiography and technology of data processing, it is possible to analysis myocardial strain bases on 3D image. The preliminary studies showed acceptable accuracy compared with strain from 2D speckle tracking or MRI tagging. It also has been shown to be an acceptable method to assess left ventricular volume and mass. Our preliminary experiences of 3D speckle tracking in hypertrophic obstructive cardiomyopathy will be presented. Recent progress of this new modality of echocardiography will be updated.