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4 Patient Information LABOR ENDERS EN DE RS Toxoplasmosis during pregnancy R Important information for women BO Transmission routes of Toxoplasma gondii: © Undercooked or raw meat Contamin. and meat vegetables products /windfall Cow Pig Sheep Goat Garden- Sand- Litter ing pit box Soil Contamination by cat faeces Newly infected cat © Labor Enders LA Pregnant women 4 Patient Information Toxoplasmosis (infection with the Toxoplasma gondii parasite) What are the possible consequences of toxoplasmosis in pregnancy? R EN DE RS In healthy pregnant women, an infection with the “Toxoplasma gondii” parasite rarely leads to symptoms. However, without treatment, a primary infection around the time of conception or during pregnancy can have consequences of varying severity for the child. These range from brain calcifications with possible convulsions up to hydrocephaly and blindness. The risk of the infection being passed from mother to child is lower if infection occurs during early pregnancy than in mid to late pregnancy. BO Who is at risk of infection? LA Around 70 % of women of child-bearing age in Germany have no antibodies against Toxoplasma gondii, and therefore no protection against a first infection. How can one get infected? © The most common sources of infection with Toxoplasma are raw or undercooked meat and meat products (e.g. raw mince, steak tartare, carpaccio, rare steak, smoked spreadable sausages such as German Teewurst and Mettwurst, cured bacon, gammon etc.), but also by contact with cat faeces (e.g. when cleaning the litter box or when gardening). EN DE RS Further sources of infection include infected raw milk (raw goat, sheep or cow milk) and unwashed food that has been contaminated with Toxoplasma (salads, vegetables, berries or fruit). R How do you know if you have toxoplasmosis? © LA BO Generally, toxoplasmosis produces no recognisable signs of illness, so that it can only be detected through antibody testing in the blood. Flu-like symptoms such as fever, headaches, tiredness, swollen lymph nodes, joint and muscle pains occur in only less than 10 % of all cases. When should you have a blood test for Toxoplasma gondii? Ideally 3–4 months prior to a planned pregnancy. Alternatively during early pregnancy or once your pregnancy has been confirmed by a doctor. 4 Patient Information Antibody testing In Germany, testing for Toxoplasma gondii antibodies in blood is paid for individually (individual health service) and will only be reimbursed by statutory health insurances upon suspicion of acute infection. RS ▶ IgG antibodies before pregnancy: (3–4 months before conception if possible) ▶ IgG (and possibly also IgM) antibodies EN DE during pregnancy: What to do if you have no antibodies: ▶ You should comply with hygiene practices; avoid certain foods (see below) R ▶ Antibody testing every 8–10 weeks If acute toxoplasmosis is detected: LA BO Specific treatment depending on stage of pregnancy is recommended. What can you do to prevent infection with Toxoplasma gondii? © Only eat meat and meat products that are thoroughly cooked through, as well as salads, fruit and vegetables that have been carefully washed. Avoid raw milk or raw dairy products. Maintain good personal hygiene after contact with cats (washing hands). Have somebody else clean cat litter boxes using hot water. Wearing gloves while gardening can protect you from direct contact with potentially contaminated soil. ® Labor Prof. G. Enders & Kollegen MVZ · Stuttgart.2013 · www.labor-enders.de