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The management of outpatients with stable coronary artery disease in clinical practice Need for contemporary data in stable CAD Data from randomized clinical trials often have limited external validity (generalizability) highly selected patient populations often limited to specific geographic settings often limited to pts with angina or with acute coronary syndrome most data pertain to hospitalized patients many studies antedate the advent of modern prescriptions In addition, there is a lack data on heart rate actually achieved in practice and its relation to outcomes CAD: coronary artery disease Worldwide contemporary registry in outpatients with stable CAD An international, prospective, observational longitudinal registry in outpatients with stable CAD The population of the CLARIFY will cover the entire spectrum of the outpatients with CAD 5 years follow-up CAD: coronary artery disease 39 countries Latvia Austria France Belgium/lLuxembourg Germany Lithuania Bulgaria Greece Netherlands Czech Republic Denmark Europe Poland Slovakia Portugal Slovenia Hungary Romania Ukraine Italy Russia Lithuania Ireland Spain Finland UK Americas Argentina Brazil Canada Mexico Asia West Indies China Middle East & Africa Korea Gulf Countries Malaysia Saudi Arabia Singapore South Africa Thailand Australia Objectives Characterize contemporary CAD patients (demographic characteristics, clinical profile) Describe their management and outcomes over 5 years of follow-up Identify gaps between treatment and evidence Determine the long-term prognostic determinants in CAD, including resting heart rate, and develop a robust risk prediction model CAD: coronary artery disease Inclusion criteria Stable coronary artery disease proven by history of at least one of the following: Documented myocardial infarction (more than 3 months ago) Coronary angiography showing at least one coronary stenosis of more than 50% Chest pain with myocardial ischemia proven by stress ECG, stress echocardiography or myocardial imaging PCI or CABG (more than 3 months ago) Data collection Follow-up Baseline 12 months 24 months 36 months 48 months 60 months Data to be collected (eCRF) History and clinical examination; regular medications Clinical examination; regular medications; clinical outcomes * Every 6 months – phone call (health status, address) Importance of CLARIFY Will provide data on HR and outcomes in “real world” contemporary outpatients with stable CAD; clinical and demographic aspects of the disease and treatment Will provide dynamic estimation of the changing patterns of HR management, disease presentation, and therapy Will help to develop a risk prediction tool based on HR Will give robust data for global and national publications, for scientific communications (congresses, abstracts), for health care administrators Will provide data for educational programs HR: heart rate CAD: coronary artery disease