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CT Seeram: Chapter 1 Computed Tomography - An Overview Early History “tomos” Greek word meaning section Sectional imaging methods first developed in 1920’s Early History: Conventional Tomography first used in 1935 image produced on film Image plane oriented parallel to film Anatomy in plane of fulcrum stays in focus anatomy outside of fulcrum plane mechanically blurred Conventional vs Axial Tomography Conventional Cut CT Axial Cut Conventional Tomography Blurring Image produced on film Objects above or below fulcrum plane change position on film & thus blur CT Image Not produced on film Mathematically reconstructed from many projection measurements of radiation intensity Digital Image calculated Acme MiniComputer Digital Image How Did We Go From… The story concerns these men. What was their Link? ??? Geoff Paul, Ringo, George, & John It Was the Late 1960’s A lot of the money was going here Follow the Money Measure Intensity of a Pencil Beam X-Ray Source Radiation Detector CT Image Measure a bunch of pencil beam intensities CT Image Now make measurements from every angle CT Image When you get done, multiple pencil beams have gone through every point in body Image Reconstruction X-Ray Source Acme MiniComputer Radiation Detector Projection (raw) Data Pixel (calculated) Data Digital Image 2-dimensional array of individual image points calculated each point called a pixel picture element each pixel has a value value represents x-ray transmission (attenuation) Digital Image Matrix 125 25 311 111 182 222 176 199 192 85 69 133 149 112 77 103 118 139 154 125 120 145 301 256 223 287 256 225 178 322 325 299 353 333 300 Numbers / Gray Shades Each number of a digital image corresponds to a gray shade for one pixel Image Reconstruction CT math developed in 1910’s Other Applications astronomy (sun spot mapping) electron microscope imaging Nuclear medicine emission tomography MRI CT History First test images in 1967 First clinical images ~ 1971 First commercial scanner 1972 CT History CT math developed in 1910’s First commercial scanner 1972 What took so long? CT History CT made possible by high speed minicomputer CT Computers Old mainframe computers too expensive & bulky to be dedicated to CT The st 1 Computer Bug CT history - Obsolete Terminology CTAT computerized transverse axial tomography CAT computerized axial tomography CTTRT computerized transaxial transmission reconstructive tomography RT reconstructive tomography Data Acquisition cross sectional image reconstructed from many straight line transmission measurements made in different directions Tube Detector Translate / Rotate CT Early Units 4 minute scans 5 minute reconstruction 80 X 80 matrix head only water bag fit tightly around head Beam Translation beam collimated to small round spot collimated at tube and collimator X-ray Tube Detector Beam Translation Tube/detector translates left to right Entire assembly rotates 1o to right Tube/detector translates right to left X-ray Tube Detector Translate - Rotate 180 translations in alternate directions 1 degree rotational increments between translations Projection Measurements Radiation detector generates a voltage proportional to radiation intensity Image Reconstruction Minicomputer does its thing Analog to Digital (A to D) conversion Digital Image Matrix Digital Matrix contains many numbers which may be Displayed on CRT Manipulated Stored 125 25 311 111 182 222 176 199 192 85 69 133 149 112 77 103 118 139 154 125 120 145 301 256 223 287 256 225 178 322 325 299 353 333 300 Digital Image Manipulation Window Level Smoothing Edge enhancement Slice reformatting 3D derived from multiple axial slices Digital Image Storage Magnetic Disk CD Tape Optical Disk PACS archive picture archival and communications system not part of CT contains images from many modalities allows viewing on connected computers CT - Improvements all CT generations measure same multi-line transmission intensities in many directions Improvements Protocol for obtaining many line transmissions # of line transmissions obtained simultaneously detector location Overall acquisition speed 2nd Generation CT arc beam used instead of Tube pencil beam several detectors instead of just one detectors intercepted arc radiation absorbent septa between detectors reduced scatter acted like grid Detectors 2nd Generation CT arc beam allowed 10 degree rotational increments scan times reduced 20 sec - 2 min 2 slices obtained simultaneously double row of detectors 10o 3rd Generation CT Wide angle fan beam rotational motion only / no translation detectors rotate with tube 30o beam Many more detectors scan times < 10 seconds 3rd Generation CT Z-axis orientation perpendicular to page Patient 4th Generation CT Fixed annulus of detectors tube rotates (no translation) inside stationary detector ring only a fraction of detectors active at once 3rd & 4th Generation (Non-spiral) CT Tube rotates once around patient Table stationary data for one slice collected Table increments one slice thickness Repeat Tube rotates opposite direction 3rd / 4th Generation Image Quality Improvements Faster scan times reduces motion artifacts Improved spatial resolution Improved contrast resolution Increased tube heat capacity less wait between scans / patients better throughput Spiral CT Continuous rotation of gantry Patient moves slowly through gantry cables of old scanners allowed only 360o rotation (or just a little more) tube had to stop and reverse direction no imaging done during this time no delay between slices dynamic studies now limited only by tube heating considerations Spiral CT Z-axis orientation perpendicular to page Patient Multi-slice CT Multiple rows of fan beam detectors Wider fan beam in axial direction Table moves much faster Substantially greater throughput Computer Improvements Reconstruction time Auto-printing protocols Image manipulation Backup time Slice reformatting 3D reconstruction And the ability to do it all simultaneously Cine CT (Imatron) four tungsten target rings surround patient replaces conventional x-ray tube no moving parts like 4 moving focal spots electron beam sweeps over each annular target ring can be done at electronic speeds 2 detector rings 2 slices detected maximum scan rate 24 frames per second Imatron Cine CT (scanned from Medical Imaging Physics, Hendee) CT Patient Dose In theory only image plane exposed In reality adjacent slices get some exposure because x-ray beam diverges interslice scatter Dose Protocols Plain X-ray entrance skin exposure Mammography mean glandular dose CT Computer tomography dose index (CTDI) Multiple-scan average dose (MSAD) CT Dose depends on kVp mA time slice thickness filtration • Noise • detector efficiency • collimation • matrix resolution • reconstruction algorithm CT Patient Dose Typically 2 - 4 rad AAPM has single slice protocol for measuring head & body doses More dose required at higher Noise resolution for same noise level More dose required to improve noise at same spatial resolution Resolution Dose Fundamental CT Tradeoff To improve one requires compromise on another Noise Resolution Dose New Stuff CT Angiography CT fluoroscopy CT virtual endoscopy / colonoscopy / ??scopy