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FLIGHT PHYSIOLOGY AND… APPLICATION TO PRACTICE Marian Williams RN BN CEN CFRN CTRN 1 2 OBJECTIVES To describe two basic aerodynamic principles. To define selected aerodynamic terms. To list and describe at least 6 stressors of flight and their applicability to patient care. To list 5 Gas laws and apply each law to at least two air medical interventions. To describe interventions for at least 5 in-flight patient conditions and transport considerations. 3 BASIC AERODYNAMICS Science of forces acting upon bodies and shapes in motion through the atmosphere Aerodyne - aircraft achieving lift from its forward motion through the air 4 FORCES OF FLIGHT LIFT GRAVITY (Weight) THRUST DRAG LIFT - Counteracts gravity (weight) -Generated by main rotor blades Is equal to gravity when in straight and level flight 5 FORCES OF FLIGHT THRUST Force generated by engines /rotor which propels the forward motion of the aircraft Also produced by tail rotor in helicopter DRAG Force generated by air moving across and around airframe and equipment Opposes thrust Caused by blades, skin friction, airflow around blades, non-lifting components of the aircraft/rotor 6 FORCES OF FLIGHT LIFT, GRAVITY(WEIGHT), THRUST AND DRAG are EQUAL when the aircraft is in straight and level flight and at a constant speed 7 8 CENTER OF GRAVITY Is the design reference point of the aircraft around which all of the aerodynamic forces are balanced and calculated Proper weight and the distribution of weight is considered for the optimum performance and safety of the aircraft 9 CENTER OF GRAVITY Each aircraft has a maximum gross weight that cannot be exceeded Altitude and temperature affect performance Distribution of weight alters center of gravity 10 CENTER OF GRAVITY Important to: Find out patient and passenger weight and number of bags Possibly restrict amount of baggage Overseas vs. domestic flight (raft adds to weight) Communicate to Pilot weights of patient and/or passenger and number of bags (Pre-flight conference) Consider small personal bags for overnight flights 11 AXIS OF CONTROL Three axes of control of the aircraft in flight LONGITUDINAL or Roll Controlled by aileron LATERAL or Pitch Controlled by elevator VERTICAL or Yaw Controlled by rudders 12 AXIS OF CONTROL 13 GRAVITATIONAL FORCES Centrifugal forces applied to the various axes of the aircraft and….its occupants 6 Basic Classifications +Gz -Gz +Gx -Gx +Gy -Gy 14 GRAVITATIONAL FORCES 15 CABIN PRESSURIZATION Creates near-the-earth atmosphere conditions Controls temperature and ventilation 16 CABIN PRESSURIZATION Atmospheric Zones Physiologic - sea level - 10,000 feet Physiologic Deficient - 10,000 - 50,000 feet • Oxygen required Space Equivalent - 50,000-250,000 feet • requires sealed cabin or full-pressure suit Space - >250,000 feet (120 miles) • requires sealed cabin or full-pressure suit • weightlessness 17 CABIN PRESSURIZATION 18 CABIN PRESSURIZATION Physiologically Deficient Zone (10K-50K) • Compensatory Stage from 10,000-15,000 feet – Increase in HR, BP, RR and depth • Disturbance Stage from 15,000-20,000 feet – Dizziness, sleepiness, tunnel vision, cyanosis • Critical Stage from 20,000-30,000 feet – Marked mental confusion and incapacitation followed by unconsciousness 19 CABIN PRESSURIZATION 20 LOSS OF CABIN PRESSURIZATION DUE TO: Structural failure (window or door) Mechanical malfunction of pressurization equipment MAY BE: Slow and gradual or SUDDEN 21 LOSS OF CABIN PRESSURIZATION Physiological Effects Hypothermia Gas Expansion Hypoxia Decreased Cardiac & Respiratory activity Decompression sickness Treatment 100% Oxygen on crew first and then patients Secure Equipment Unclamp Chest tubes and Catheters Descend below 10,000 feet 22 STRESSORS OF FLIGHT a. Decreased partial pressure of Oxygen b. Barometric Pressure Changes c. Thermal Changes d. Humidity e. Noise f. Vibration g. Fatigue h. Gravitational Forces i. Third Spacing 23 STRESSORS OF FLIGHT a. Decreased Partial Pressure of Oxygen 1. Hypoxic hypoxia • Decrease in alveolar oxygen exchange • Interferes with ventilation and perfusion • If requires O2 at sea level - then O2 will be a significant issue at altitude Maximum altitude: 8000 feet Restrict to 5000 feet Respiratory disease with VC <900 ml Recent MI Cardio-pulmonary disease Hgb <9; Hct <25 Diving within 24 hours Thoracic or abdominal surgery within one week 24 STRESSORS OF FLIGHT a. Decreased Partial Pressure of O2 ALTITUDE SEA LEVEL 10,000 FEET 22,000 FEET SATURATION 98% 87% 60% 25 STRESSORS OF FLIGHT a. Decreased Partial Pressure of O2 2. Hypemic Hypoxia • Reduction in oxygen-carrying capacity of blood • Causes: – – – – – Anemia Hemorrhage Hgb. Abnormalities e.g. sickle cell Drugs - sulfur, nitrites Chemicals - CO, cyanide, cigarette smoke, exhaust fumes 26 STRESSORS OF FLIGHT a. Decreased Partial Pressure of O2 3. Stagnant Hypoxia - reduction in total cardiac output from pooling of blood, reduction in flow to tissues or restriction of blood flow Causes: • Respiratory failure, shock, acceleration, PE • Extremes in temperature, continuous positive pressure ventilation, postural changes, hyperventilation, tourniquets (restrictive clothes, seat belts) • Embolism, CVA, PEEP, arterial spasm, CHF 27 STRESSORS OF FLIGHT a. Decreased Partial Pressure of O2 4. Histotoxic Hypoxia (tissue poisoning) • Inability of cells to use molecular oxygen • Causes: – CO, cyanide, alcohol, medications 28 STRESSORS OF FLIGHT a. Decreased Partial Pressure of O2 ii. EPT and TUC • Effective performance time (EPT) – Amount of time an individual is able to perform USEFUL flying duties in an environment of inadequate oxygen • Time of useful consciousness (TUC) – Elapsed time from point of exposure to an oxygen deficient environment to a point where deliberate function is lost 29 STRESSORS OF FLIGHT a. Decreased Partial Pressure of O2 TUC Influence by: • Rate of ascent , Physical fitness, Physical activity, • Temperature, Individual tolerance, Self-imposed Stresses 30 ALTITUDE and TUC 31 STRESSORS OF FLIGHT a. Decreased Partial Pressure of O2 Causes of Hypoxia • • • • • High Altitude Hypoventilation Pathological Condition of the Lung Malfunctioning Oxygen Equipment Miscalculation of Oxygen Needs 32 GRAPH 33 STRESSORS OF FLIGHT a. Decreased Partial Pressure of Oxygen Treatment of Hypoxia • • • • • 100% Oxygen delivered with Positive Pressure Monitor breathing- control hyperventilation Monitor equipment - Pre-Flight Checks Descend Increase fluids, Prevention 34 STRESSORS OF FLIGHT a. Decreased Partial Pressure of Oxygen iii. Hyperventilation • Is abnormal increase in rate and depth of breathing • Causes: – Psychological stress – Environmental stress - Hypoxia, Vibration, Heat – Drugs - Salicylates, Female hormones 35 STRESSORS OF FLIGHT a. Decreased Partial Pressure of Oxygen iii. Hyperventilation • Treatment – – – – Administer 100% Oxygen Check Equipment Distraction techniques Descend 36 STRESSORS OF FLIGHT b. Barometric Pressure Changes • Boyle’s Law - trapped or partially trapped gases within certain body cavities – – – – – – Barotitis Media Barosinusitis Barondontalgia Barobaric Trauma GI Effects Miscellaneous Effects 37 STRESSORS OF FLIGHT b. Barometric Pressure Changes Ascent • Pressure is decreased and gases expand Descent • Pressure is increased and gases contract 38 STRESSORS OF FLIGHT b. Barometric Pressure Changes AKA - Atmospheric pressure Pressure exerted against an object or person by the atmosphere Sea level - 15 pounds per square inch AKA psi (14.7 to be exact) As altitude increases, psi decreases 39 B. BAROMETRIC PRESSURE b. Barometric Pressure Cabin Pressurization • Maximum Pressure Differential: – LEAR - 9.2 lbs. per square inch – GULFSTREAM - 9.6 lbs./square inch – AIRBUS 319 /320 - 8.6 lbs./square inch – BOEING 777 – 8.0 lbs./square inch – Boeing 787 Dreamliner -9.8 lbs./square inch As altitude increases air is pumped into cabin to pressurize and is constantly being exchanged to maintain oxygen levels i.e. Aluminum balloon with no expansion properties 40 Altitude/Volume/Pressure Relationships 41 STRESSORS OF FLIGHT b. Barometric Pressure Changes • a. Barotitis Media – Failure of ventilation of middle ear via Eustachian tube – Severe pain, tinnitus, vertigo, nausea, petechial hemorrhage in ear – Ascent: Gas volume in middle ear expands and is passively expelled through the Eustachian tube – Descent: Gas volume in middle ear contracts creating a negative pressure within the middle ear and Eustachian tube collapsing and preventing equalization of pressure with atmosphere 42 STRESSORS OF FLIGHT b. Barometric Pressure Changes • a. Barotitis Media – Incidence » Increased at lower altitudes and on descent » Increased with URI – Management » Yawn, swallow, Valsalva » Re-ascend and slow descent » Topical vasoconstrictors - e.g. Neosynephrine nasal spray 43 STRESSORS OF FLIGHT b. Barometric Pressure Changes • a. Barotitis Media – Increased incidence with patients with head, facial or neck trauma – Treatment for Patients » Wake sleeping patients » Tell patients to yawn or swallow, chew gum, if able, suck on hard candy » Give babies a pacifier to suck – May be delayed reaction if on 100% O2 related to absorption of oxygen by the middle ear 44 Middle Ear / Eustachian Tube 45 STRESSORS OF FLIGHT b. Barometric Pressure Changes • b. Barosinusitis – Inflammation of soft tissue within the frontal and maxillary sinus particularly resulting from positive and negative internal pressure changes developing in response to altitude changes – Signs and Symptoms » Severe pain, maxillary gum pain, teeth pain, facial pain, lacrimation, epistaxis » Increases on ascent 46 STRESSORS OF FLIGHT b. Barometric Pressure Changes • b. Barosinusitis – Interventions » Re-ascend and slow Descent » Direct pressure on sinuses » Topical vasoconstrictors 47 Facial Sinuses 48 STRESSORS OF FLIGHT b. Barometric Pressure Changes • c. Barodontalgia – Severe toothache from gas expansion may occur in teeth with defective fillings, decay or abscesses – Treatment » Reascent and slow descent » Warm compresses, analgesia, » Restrict flight duty 48-72 hours after deep reconstruction 49 STRESSORS OF FLIGHT b. Barometric Pressure Changes • d. Barobaric (Barobaro)Trauma – Occurs in obese people with large amounts of adipose tissue – High concentrations of nitrogen occur with pressure changes – Fragile cell membranes weaken allowing release of nitrogen with large concentrations of lipids predisposing the patient to fat and nitrogen emboli – Signs and Symptoms: SOB; chest pain, petechiae, pallor, tachycardia – Treatment: 100% oxygen 15 minutes prior to transport to decrease nitrogen level 50 STRESSORS OF FLIGHT b. Barometric Pressure Changes • 5. Gastrointestinal Effects Gases within alimentary canal expand at a higher rate than gases in other body tissues due to presence of volatile digestive fluids within the GI tract ( wet gases expand to a greater extent than dry) » 1 liter of gas at sea level equals 1.5 liters at 9000 feet » Intestinal volume may increase 30% at 7-8000 feet » Occur more in patients with disruption of bowel function » Hiatal hernia & GERD patients increased eructation and pain during ascent 51 STRESSORS OF FLIGHT b. Barometric Pressure Changes • e. Gastrointestinal effects – Signs and Symptoms » Pain, Nausea, Vomiting, Hyperventilation, SOB » Pressure on diaphragm and decrease expansion especially in pediatric patients » Syncope - from reflex venous pooling of the blood caused by overdistention of the abdominal organs thus decreasing cardiac preload, hypotension and decreased tissue perfusion » Possibly shock 52 STRESSORS OF FLIGHT b. Barometric Pressure Changes • e. Gastrointestinal effects – Staff Interventions » Avoid carbonated beverages and gas producing foods » Avoid chewing gum & avoid eating just prior to flight – Patient Interventions » Stop Gastric feedings at least 4 hrs. prior to flight to prevent risk of aspiration from turbulence » Vent Gastric tube several times during flight » Vent colostomy bags » Provide airway management if necessary » Reposition patient; abdominal massage 53 STRESSORS OF FLIGHT b. Barometric Pressure Changes • f. **Respiratory System – Lung tissue is easily stretched and collapsed in response to pressure and volume changes of gases – Ascent » Can cause a pneumothorax to expand as barometric pressure drops » If lung tissue is compressed and no gas expansion occurs, intrathoracic pressure will begin to rise » Compression of vascular structures occurs, decreased cardiac preload, and decreased tissue perfusion 54 STRESSORS OF FLIGHT b. Barometric Pressure Changes • f. Respiratory System – Sudden loss of cabin pressurization may cause gases within the air passages to expand in an explosive manner leading to pulmonary overpressurization – Trapped gases can be forced into potential spaces causing pneumothorax, mediastinal emphysema and air embolism – Caution » Chest trauma patients » Patients with >20% pneumothorax have a chest tube placed prior to flight 55 STRESSORS OF FLIGHT b. Barometric Pressure Changes • f. Respiratory System – Caution » A 50% Pneumothorax on the ground will become 75% at 10,000 feet » Chest tubes may clot off from lack of flow » If chest tube is removed, wait 48-72 hours prior to fixed wing transport unless sea level altitude can be maintained » ETT and Trach tube balloons expand with ascent and contract with descent - partially deflate on ascent and reinflate on descent or use sterile water (Long flights at altitude primarily) Not usually needed for short rotor flights under 10,000 feet 56 Lung Expansion 57 STRESSORS OF FLIGHT b. Barometric Pressure Changes • g. Cardio-Vascular System – Decreased Cardiac Output » Decrease venous return if expanding gas volumes within thoracic and abdominal cavities create pressure on vena cava » Fat/Air Embolism - Barobaric trauma – Caution » Hypotensive patients with air trapped in chest or abdomen » Obese patients exposed to rapid decompression 58 STRESSORS OF FLIGHT b. Barometric Pressure Changes • h. Extremities » Soft tissue swelling in injured extremity with decreased barometric pressure » May be a particular problem in patients with a tight fitting splint or cast » Check distal circulation frequently » May need to bivalve the cast » If pneumatic splint applied, will need to release pressure during ascent » If MAST suit used, on descent, it will deflate and patient may experience hypotension (has release valve when pressure exceeds 90 mm Hg) 59 STRESSORS OF FLIGHT b. Barometric Pressure Changes • i. Decompression Sickness – Cause: » Rapid Decompression » Extended exposure to altitudes over 18,000 feet » Rapid ascent to altitudes above 25,000 feet – Symptoms » Pain in joints of arms or legs; visual disturbances; » Headaches; dizziness; unilateral paresthesia; confusion » Personality changes 60 STRESSORS OF FLIGHT b. Barometric Pressure Changes • i. Decompression Sickness – ‘Bends’ - limb pain – ‘Creeps- - skin irritation – ‘Staggers’ - disturbances of CNS – ‘Syncope’ - cardiovascular collapse – ‘Chokes’ - SOB associated with a burning sensation in mediastinum and a dry cough 61 STRESSORS OF FLIGHT b. Barometric Pressure Changes • i. Decompression Sickness – Symptoms » Cardio-pulmonary arrest secondary to massive PE » Onset of symptoms may be immediate or delayed up to 6 hours – Management » Oxygen preflight » Rapid descent » 100% O2 » Splint affected limbs » Transport to hyperbaric facility 62 STRESSORS OF FLIGHT b. Barometric Pressure Changes • j. Miscellaneous – A. IV Rates » Ascent - air volume expands and increases drip rate » Descent-air column contracts & decreases drip rate » Air volume expansion in glass bottles could break them » Remedies Always use IV pumps Plastic IV bags 63 STRESSORS OF FLIGHT b. Barometric Pressure Changes • i. Miscellaneous – B. Pregnancy » Altitude changes can increase intestinal gas and increase pressure on uterus and cause or increase contraction and fetal activity » 1000-7000 feet - fetal hypoxia unlikely due to fetal blood has increased capacity to carry oxygen » If uteroplacental unit is healthy and mother’s condition is not severely compromised, fetus can tolerate up to 30 minutes of decreased oxygen supply 64 STRESSORS OF FLIGHT b. Barometric Pressure Changes • 9. Miscellaneous – B. Pregnancy » Caution for conditions that decrease placental ability to supply oxygen to fetus: » Placenta abruptio » Maternal hemorrhage » Pre-eclampsia (PIH) » Eclampsia – Pre-eclamptic patient is at risk for pulmonary edema due to increased vessel wall permeability » Altitude & gas expansion increases permeability 65 STRESSORS OF FLIGHT b. Barometric Pressure Changes • 9. Miscellaneous – B. Pregnancy » G forces » Positive acceleration increases ventilation differences that may already be present » Increased chance of further dilatation of cervix and rupture of bulging membranes » Can increase pressure of fetus against cervix 66 STRESSORS OF FLIGHT b. Barometric Pressure Changes • 9. Miscellaneous – Pregnancy – Remedies » Patient position-safety straps low on pelvic girdle » For advanced dilatation and amniotic sac protrusion, place patient head at the back to decrease pressure on cervix during takeoff » Patient in left lateral position to decrease uterine pressure on vena cava » Oxygen administration » Patient NPO » Patient voided 67 STRESSORS OF FLIGHT b. Barometric Pressure Changes • 9. Miscellaneous – C. Penetrating Eye Injuries » Caution: » May rupture eyeball unless flown at sea level – D. Pressure Monitoring Devices » Re-zero upon reaching altitude 68 STRESSORS OF FLIGHT c. Thermal Changes – With each 1000 feet altitude increase there is a corresponding 3 degree F. decrease in temperature – Hyper- and hypo- thermia increase the body’s oxygen requirements – Increased altitude - humidity falls – Patient Interventions » Blankets; pad sides of aircraft, warm IV solutions » Warm fluids, if possible; cover head (especially pediatric patients) » Increase aircraft temperature; remove wet dressings » Trauma patients more susceptible 69 STRESSORS OF FLIGHT d. Humidity As altitude increases, humidity decreases 90% of atmospheric moisture is concentrated under 16,000 feet Long flights - particularly dry • Signs and Symptoms – Increased hypoxia due to dry, mucous membranes and thick secretions – Dehydration stimulates hypothalmus to increase body’s BMR and increase Oxygen demand 70 STRESSORS OF FLIGHT d. Humidity • Remedies – – – – Humidified oxygen at all times Increase patient’s fluid intake especially on long flights Increase IV fluid rate if the patient is NPO Trauma patients are more susceptible 71 STRESSORS OF FLIGHT e. Noise • Measured in terms of Frequency and Intensity • Intensity - measured in decibels – – – – Heart beat - 10 dB Jet engine at full power - 170 dB Intensities >140 dB - also felt as vibration Generally inside cabin (rotary and fixed wing) - 100120 dB – 80 dB- one must shout to be heard – Can tolerate <80 dB for 8 hours/day -no hearing impairment • Frequency - pitch 72 STRESSORS OF FLIGHT e. Noise • Effects – – – – – – – – Distraction and mental fatigue Mild C-V stimulation increases oxygen consumption Nausea Visual disturbance Mild vertigo Temporary or permanent hearing loss Fullness and ringing in the ears Decreased concentration 73 STRESSORS OF FLIGHT e. Noise • Interventions – Helmets – Ear plugs (filter 15-20 dB) – May use Doppler and and NIBP devices to hear blood pressures – Develop skills of palpation and inspection 74 75 STRESSORS OF FLIGHT f. Vibration • Is a power source traveling over turbulence in air • Rotor - worse at a hover • Fixed wing - storm cloud penetration or high speed, low level flight • Low frequency motion sickness, fatigue, SOB, abdominal and chest pain • Increases bubbling and back flow in equipment for example, oxygen humidifiers 76 STRESSORS OF FLIGHT f. Vibration • Physiological Effects – Increased metabolic rate, increased RR, HR – Redistribution of blood flow with peripheral vasoconstriction – Disturbance of dynamic visual acuity, speech and fine muscle coordination • Interventions – Avoid direct contract with aircraft frame – Secure patient; provide adequate padding and skin care – Loosen clothing, use oxygen, focus eyes outside aircraft – Position changes 77 STRESSORS OF FLIGHT f. Vibration • Equipment Effects – Cause artifact on cardiac monitors – Pulse oximeters may fail to lock in peripheral pulse – Pacemakers may malfunction 78 STRESSORS OF FLIGHT g. Fatigue End product of all of the stresses or flight as they affect the human body Contributing factors • • • • • • Poor cardiovascular conditioning Smoking; alcohol usage Medication / drug ingestion Dehydration; unbalanced diet Inadequate rest / erratic schedule Noise, vibration, hypoxic environment 79 STRESSORS OF FLIGHT g. Fatigue DEAT H • D - Drugs – Antihistamines especially • E - Exhaustion – Personal stress • A - Alcohol – No ingestion for 12 hours; effects accentuated at altitude • T - Tobacco – CO combines with Hgb and contributes to loss of nite vision • H - Hypoglycemia 80 STRESSORS OF FLIGHT g. Fatigue Jet Lag • Complex bodily functions (reaction, performance and decision times) are affected by rapid shifts through several time zones • It takes one 24 hour period per one hour shift in time zone to recover – e.g. cross 4 time zones = 4 x 24 hours to adjust bodily cycles • Individual variation 81 STRESSORS OF FLIGHT h. Gravitational Forces • Speed - rate in the direction of travel • Velocity - rate and direction • Acceleration - rate of change of velocity – Linear - acceleration - change of speed and no change in direction – Radial - acceleration - change of direction without a change of speed • Weight - force exerted by the mass of the accelerating body • Mass - inertia of an object 82 STRESSORS OF FLIGHT h. Gravitational Forces 1 G is the force exerted upon a body at rest Axis - longitudinal, lateral and vertical Patient Considerations • Patient location and position before takeoff and landing » During acceleration there is decreased venous return and therefore decreased CMO, pooling of fluid in lower extremities » CMO decreases with a rapid rate of climb 83 STRESSORS OF FLIGHT h. Gravitational Forces Patient Considerations • During Ascent – Patient with head at front of aircraft » Fluid pools in lower extremities » Decrease risk of transient increase of ICP » e.g. Patient with risk of intracranial bleed » Patient with head injury » Patient with fluid overload • During Descent – Opposite of above 84 STRESSORS OF FLIGHT h. Gravitational Forces Patient Considerations • Cardiac Patients – Head at back of aircraft for takeoff (head flat) » Blood will pool in upper part of body which may assist in myocardial perfusion 85 STRESSORS OF FLIGHT h. Gravitational Forces Patient Considerations • Head Injury Patient (if head flat) – Head facing back of plane for takeoff • Fluid Overload Patient (if head flat) – Head should be facing back of plane for takeoff • Intrathoracic Injuries (if head flat) – Head should be facing back of aircraft for takeoff • Intraocular Injuries (if head flat) – Head should be facing back of aircraft for takeoff 86 STRESSORS OF FLIGHT h. Gravitational Forces Positive G forces (acceleration) • • • • Blood pooling in lower extremities Increased intravascular pressures Stagnant hypoxia e.g. pushed against seat Negative G forces • Stagnant hypoxia (deceleration) • Blood pooling in upper body • e.g. fall out of seat; fall through trap door 87 STRESSORS OF FLIGHT i. Third Spacing • Loss of fluid from the intravascular to extravascular tissue secondary to a decrease in ambient pressure surrounding the vessel walls • Associated with long distance or high altitude flights • Aggravated by existing fluid leaking, cardiac disease and nephrotic disease • Affected by exposure to excessive G forces, vibration and temperature extremes 88 STRESSORS OF FLIGHT i. Third Spacing • Signs and Symptoms – – – – – – Edema Tachycardia Hypotension Dehydration Tachypnea Shortness of breath • Remedies – Rest; adequate fluids; no alcohol within 12 hrs of flight – No tobacco – Small frequent meals 89 ELECTROMAGNETIC INTERFERENCE D. Electromagnetic Interference May be generated by all types of electronic device Medical equipment may affect aircraft, navigational and communication systems Notify pilots prior to defibrillation, cardioversion or pacing 90 GAS LAWS Govern body responses to changes in: Barometric pressure Temperature Critical as the aircraft Ascends Descends Volume 91 GAS LAWS BOYLE’S LAW HENRY’S LAW DALTON’S LAW GRAHAM’S LAW CHARLES’ LAW 92 GAS LAWS a. Boyle’s Law Volume of a gas is inversely proportional to the pressure to which that gas is exposed i.e. - Gas volume expands proportionately to decreases in barometric pressure Closed containers expand as altitude increases e.g. e.g. E.T./T.T balloon Foley catheter balloon, E.g. IV bags, IV glass containers e.g. Stomach, lungs, bladder, bowel, sinuses, uterus 93 GAS LAWS 94 GAS LAWS a. Boyle’s Law Volume of the air or gas increases in a closed body cavity or equipment space because the external pressure is decreasing Formula P1V1= P2V2 1 - Initial pressure 2 - Final pressure 95 GAS LAWS a. Boyle’s Law Lungs expand • Pneumo-thorax will increase with altitude • Rate and depth of respiration • Increased intrathoracic pressure Bladder • Increased desire to urinate Sinuses, Teeth Increase pain Stomach and Bowels Increased gas Increased pain Increased pressure on diaphragm Uterus Brain hemorrhage 96 GAS LAWS a. Boyle’s Law Caution • Transporting patients with a pneumothorax or pneumocephaly • Transporting patients with tube feedings (stop same prior to transport) • Empty bladder - Foley / Void • Women in labor • Patient with distended and/or bowel obstruction 97 GAS LAWS a. Boyle’s Law Electronic controlled ventilators - no effect Need IVAC Mini-med to infuse all IV’s on controls Equipment needs to Flow rate of O2 may be rechecked and change, though recalibrated at Oxygen cylinder altitude and again at ground level pressures 98 GAS LAWS a. Boyle’s Law Pilots can control pressure inside cabin to a certain extent Pilots perhaps can fly at a lower altitude Perhaps may decide not to take the patient 99 GAS LAWS b. Dalton’s Law of Partial Pressures The pressure of a gaseous mixture is equal to the sum of the partial pressures of the gases in that mixture As altitude increases and barometric or atmospheric pressure decreases, gas expansion causes the AVAILABLE oxygen to decrease as the gas molecules move farther apart 100 GAS LAWS b. Dalton’s Law of Partial Pressures Pt = P1 + P2 + P3…..Pn 101 GAS LAWS 102 GAS LAWS 103 GAS LAWS 104 GAS LAWS 105 GAS LAWS Dalton’s Law b. Barometric pressure multiplied by the concentration of a gas is equal to the partial pressure of the gas Therefore, hypoxia occurs with flight to higher altitudes • (Oxygen molecules are present but are farther apart) 106 GAS LAWS b. Dalton’s Law Remedies: • Increase oxygen liter flow • Increase oxygen percentage by using alternate methods of O2 administration • Fly at lower altitude 107 GAS LAWS c. Charles’ Law At a constant pressure, the volume of a given gas is directly proportional to the absolute temperature of that gas (if mass and pressure are held constant) Increases in temperature cause gas molecules to move faster thus exerting greater force and leading to volume expansion 108 GAS LAWS c. Charles’ Law e.g. As the temperature decreases, the pressure reading in the oxygen tank decreases (the converse is true) e.g. If the patient’s temperature increases, the PO2 decreases 109 GAS LAWS c. Charles’ Law For example, O2 delivered by a ventilator may be 72 degrees F, so Tidal Volume increases as the oxygen is heated by the body 110 GAS LAWS c. Charles’ Law Remedies • Maintain cabin at constant temperature (CAMTS – 85 degrees F.) • Pad aircraft interior that touches patient • Maintain patient’s temperature as near normal as possible 111 112 GAS LAWS d. Henry’s Law The quantity of gas dissolved in a liquid is directly proportional to the pressure of that gas above the liquid. i.e. The more pressure that is exerted above a liquid, the amount of that gas dissolved in the liquid will increase P1 = P2 A1 A2 113 GAS LAWS d. Henry’s Law e.g. Bottle of Perrier water opened e.g. Only a few cells separate atmospheric gases from the alveolar- capillary membrane in the lungs. As pressure is reduced, the amount of gas dissolved in the solution is reduced, leading to hypoxia and nitrogen gas bubble formation Decompression sickness (diver ascends too rapidly) 114 115 GAS LAWS e. Graham’s Law of Gaseous Diffusion Rate of diffusion of a gas through a liquid medium is directly related to the solubility of the gas and is inversely proportional to the square root of its density or gram molecular weight • i.e. Gases will go from a higher pressure or concentration to a region of lower pressure or concentration 116 GAS LAWS e. Graham’s Law As altitude increases, the faster the rate of CO2 is 19 times more diffusible than oxygen diffusion of O2 out of CO is about 200 times the tissues and more diffusible than therefore a rapid oxygen drop in TUC 117 GAS LAWS e. Graham’s Law Remedies • Increase oxygen flow and FiO2 • Decrease cabin pressure • Fly at lower altitude 118 F. IN-FLIGHT EMERGENCIES Cardio-Pulmonary arrest Cardiac Tamponade Accidental Extubation Cardiac Dysrhythmias Hypovolemia Tension Pneumothorax Hypotension 119 FLIGHT PRACTICE HINTS PRE-FLIGHT CHECKS As per Pre-Flight Check List Check ALL equipment operations Know what is in your packs - check each flight! Have extra IV supplies in flight suit Have ‘stash’ of emergency drugs close by Know how to use hands-off pacer/defibrillator pads 120 FLIGHT PRACTICE HINTS Always call for patient report prior to leaving for flight Call receiving hospital to ensure that they are expecting the patient Place anticipated articles in one place Your pilots are good sources of information and assistance Keep overnight bag with you at all times Keep emergency items with you - e.g. matches, candle, water 121 Variable Gas Distribution Relation to Latitude Prevailing environmental temperature varies from earth’s poles to equator The Cooler temperatures at the poles cause gas volume to shrink (Charles’ Law) resulting in greater gas density near the earth’s surface-the converse is true near the equator Greater physiological stresses are experienced in colder environments 122 Variable Gas Distribution Related to Altitude Gases are not uniformly distributed throughout the different altitudes (curve) Air density is greater in lower atmosphere Uneven distribution of gases results in greater barometric change per unit of altitude change in lower atmospheres As amount of Barometric Pressure change increases, the potential for adverse physiological effects also increases 123 124 SUMMARY Aerodynamics of Flight review Stressors of flight and Gas Law effects alter you and your patients’ responses. Know your equipment and be proactive and prepared for emergencies. 125 THANK YOU! 126