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PERIORBITAL VS ORBITAL
CELLULITIS
Morning Report 7/25/12
Melanie McIntosh
Anatomy
Pathogenesis
Rhinosinusitis (especially ethmoiditis)
 Extension of external ocular infection

 Stye,
dacryocystitis/dacryoadenitis
Skin trauma (insect bites, acne, surgery)
 Dental abscess
 Hematogenous seeding

Epidemiology
Periorbital Cellulitis



More common overall
Age <5yrs
M=F
Orbital Cellulitis

All ages
 Average:


6.8 yrs
2:1 M>F
Associated with
sinusitis and URIs
 More
common in winter
Clinical Presentation

Unilateral erythema, edema, warmth, tenderness of
eyelid
Fever, systemic illness can be seen

Orbital Cellulitis – increased intra-orbital pressure

Vision changes (i.e. diplopia)
 Ophthalmoplegia
 Proptosis
 Chemosis
 Limited EOM
 Reduced visual acuity
 Abnormal light reflexes

Differential Diagnosis

Edema
 Allergic
Reaction
 Hypoproteinemia
 Sickle Cell – orbital wall infarction, subperiosteal
hematoma

Proptosis
 Orbital
Pseudotumor
 Graves Disease - exophthalmos
Diagnostic Work-up

Periorbital Cellulitis – typically clinical dx


Orbital Cellulitis



EOMI
Elevated WBC, CRP, ESR (but DO NOT use alone to make
the diagnosis!)
Wound Culture
CT Scan c contrast
Edema  unable to examine eye
 CNS involvement
 Loss of visual acuity, proptosis, ophthalmoplegia
 Worsening/no improvement after 24-48hrs tx

Contrast CT – Orbital Cellulitis
Proptosis
 Intraorbital free air
 Diffuse fat infiltration

Indications for Inpatient Admission


Diplopia, loss of visual acuity, abnormal light
reflexes, proptosis, ophthalmoplegia
CNS Involvement
 Lethargy,
vomiting, HA, seizures, focal deficits, altered
mental status

Inability to fully examine eye
Pathogens

75% Staph & Strep
 S.
epidermidis, S. aureus, S. pyogenes
 MRSA
H. influenza type b
 S. pneumo
 Polymicrobial

 Especially
seeding from dental abscess
Treatment
Periorbital Cellulitis





Staph and Strep
coverage
MRSA
PO = IV
7-10 days
Should see
improvement in
24-48hrs
Orbital Cellulitis





Coverage for Staph,
Strep, and organisms
causing rhinosinusitis
MRSA
10-14 days
Start with IV, but may
switch to PO after
seeing improvement
Surgery
Complications – Periorbital Cellulitis

Recurrent Periorbital Cellulitis (RPOC)
3
infections within 1 yr, spaced by at least one month
 Not due to treatment failure
 Underlying causes
 Atopy
 Nonbacterial
organisms – HSV, Mycobacteria
 Collagen Vascular Disorders
 Structural abnormalities
 Immunosuppression
Complications – Orbital Cellulitis

Cavernous Sinus Thrombosis
 Acute
or slowly progressive symptoms of orbital
cellulitis
 Proptosis,
 Late

periorbital edema, and ophthalmoplegia
Signs: vision loss, meningismus
Intracranial Infections
 Subdural
empyema, Intracerebral abscess, Extradural
abscess, Meningitis

Optic Nerve Damage – vision loss
 Septic
emboli
 Compression  ischemia