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Chapter 2 Basic Exercise Science Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Purpose • To provide the fitness professional with the fundamental concepts that pertain to the definition, structure, and function of the human movement system (kinetic chain). • By understanding basic anatomic structures and physiologic functions, the fitness professional will gain comprehensive insight into how the human body operates. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Objectives • After this presentation, the participant will be able to explain the basic structure and function of: • The nervous system • The skeletal system • The muscular system • The endocrine system • The participant will also be able to describe how these systems respond and adapt to exercise. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Introduction Human Movement System: • Movement is accomplished through the functional integration of three systems: the nervous, skeletal, and muscular systems. • These systems work in concert to produce motion (kinetic) or human movement. • All components must work together to produce sound movement; if one component is not working well, it will affect the others and cause kinetic chain impairments. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Kinetic Chain The kinetic chain • Kinetic means force(s); chain refers to a system that is linked together or connected. • All components work together to manipulate human motion. • If one component of the kinetic chain is not working properly, it will affect the others and ultimately affect the movement. Kinetic Chain Nervous System Muscular System Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Skeletal System The Nervous System • The nervous system is one of the main organ systems of the body and contains specialized cells that transmit and coordinate signals, providing a communication network within the body. • The nervous system comprises two main components: • The central nervous system (CNS) is composed of the brain and spinal cord. • The peripheral nervous system (PNS) is the nerves that communicate with the CNS. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins The Nervous System • The nervous system is a communication network within the human body that allows us to gather information about our internal and external environments, process and interpret the information, and respond. • Its three primary functions are: • Sensory • Integrative • Motor Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins The Nervous System • Sensory: The ability of the nervous system to sense changes in either the internal or external environment. • Integrative: The ability of the nervous system to analyze and interpret the sensory information to allow for proper decision making, producing the appropriate response. • Motor: The neuromuscular response to the sensory information. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Proprioception • The body’s ability to sense the relative position of adjacent parts of the body. • Training the body’s proprioceptive abilities will improve balance, coordination, and posture and enable the body to adapt to its surroundings without consciously thinking about movement. • Thus, it becomes important to train the nervous system efficiently to ensure proper movement patterns, which enhances performance and decreases the risk of injury. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins The Nervous System • Movement is a response to our sensory information and is, therefore, dictated by the nervous system. • This reflects the importance of training in a multisensory environment. • The most effective way to create positive long-term results in a client is to directly affect (properly train) his or her nervous system. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins The Neuron • The functional unit of the nervous system is known as the neuron. • Neurons are composed of three main parts: • Cell body: Cell organelles (nucleus, mitochondria, lysosomes, and Golgi complex) • Axon: Provides communication from the brain or spinal cord to other parts of the body • Dendrites: Responsible for gathering information from other structures of the body Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins The Neuron There are three main functional classifications of neurons determined by the direction of their nerve impulses: • Sensory: Transmits afferent nerve impulses from receptors to the brain or spinal cord • Motor: Transmits efferent nerve impulses from the brain or spinal cord to the effector sites, such as muscles or organs • Interneuron: Transmits nerve impulses from one neuron to another Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Central Nervous System The CNS consists of the brain and the spinal cord. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Peripheral Nervous System • Contains 12 cranial nerves and 31 pairs of spinal nerves (that branch out from the brain and spinal cord, respectively) as well as all sensory receptors. • Function: • • Provide a connection for the nervous system to activate different bodily organs such as muscles (motor information). Relay information from the bodily organs back to the brain, providing a constant update of the relation between the body and the environment (sensory information). Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Peripheral Nervous System Two further subdivisions of the PNS include the somatic and autonomic nervous systems: • The somatic nervous system consists of nerves that serve the outer areas of the body and skeletal muscle and are largely responsible for the voluntary control of movement. • The autonomic nervous system supplies neural input to the involuntary systems of the body. • The autonomic system is further divided into the sympathetic and parasympathetic nervous systems. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Sensory Receptors • Specialized structures located throughout the body, designed to transform environmental stimuli (heat, light, sound, taste, and motion) into sensory information that the brain or spinal cord can interpret to produce a response: • Mechanoreceptors respond to mechanical forces (touch and pressure). • Nociceptors respond to pain (pain receptors). • Chemoreceptors respond to chemical interaction (smell and taste). • Photoreceptors respond to light (vision). • For relevance to this course, we will focus attention on the mechanoreceptors. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Mechanoreceptors • Muscle spindle: Sensitive to change in length and rate of length change in muscle. • Golgi tendon organ: Sensitive to changes in muscular tension and rate of tension change. • Joint receptors: Respond to pressure, acceleration, and deceleration of the joint. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Physical Activity and the Nervous System • Early stage improvements to physical activity are largely due to changes in the way the CNS and PNS coordinate movement. • Unsuccessful activity can be modified with sensory input to improve performance. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins The Skeletal System • Framework for our structure and movement. • Resting ground for the muscles of our body. • Bones form junctions that are connected by muscles and connective tissue known as joints. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Divisions of the Skeletal System • Axial skeleton: • Skull • Rib cage • Vertebral column • Appendicular skeleton: • Upper and lower extremities • Shoulder and pelvic girdles Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Bone Growth Bones under go remodeling throughout life cycle: • Osteoclasts break down old bone tissue. • Osteoblasts build up new bone tissue. • Remodeling is the constant process of these cells. • In children, osteoblasts are more active; as we age, osteoclasts become more active. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Types of Bones Long bones: • Long cylindrical shaft and irregular or widened ends • Epiphysis: End of long bone • Diaphysis: Shaft of long bone; main production of red blood cells (RBCs) • Epiphyseal plate: Where bone growth (length) occurs Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Types of bones Long bones: • Periosteum: Tough membrane that coats bone • Medullary cavity: Central cavity of bone where marrow is stored • Articular cartilage: Cartilage that covers the articular surfaces of bones Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Types of Bones Short bones: • Similar in length and width and appear somewhat cubical in shape Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Types of Bones Flat bones: • Thin, protective Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Types of Bones Irregular bones: • Unique shape and function Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Bone Markings Depressions: • Flattened or indented portions of the bone • Common depressions: • • Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Fossa Sulcus Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Bone Markings Processes: • Projections protruding from the bone to which muscles, tendons, and ligaments attach • Common processes: • Condyle • Epicondyle • Tubercle • Trochanter Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Vertebral Column Vertebral column: • Series of irregularly shaped bones called vertebrae. • Houses the spinal cord. • Cervical spine has 7 (concave curve) • • • • vertebrae. Thoracic spine has 12 (convex curve). Lumbar spine has 5 (concave curve). Sacrum is fused triangle attached to pelvis. Coccyx is tail bone. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Joints • One bone that articulates with another bone. • Joint motion is referred to as arthrokinematics. • Typical joint motions seen in the human articular system include: • Roll: Rolling on joint surface on another such as femoral • • condyles rolling over the tibial condyles during a squat Slide: Sliding of a joint surface across another such as tibial condyles moving (sliding) across the femoral condyles during a knee extension Spin: Rotation of one joint surface on another such as head of the radius rotating on the end of the humerus during pronation and supination of the forearm Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Classifications of Joints • Synovial joints: • Produce synovial fluid • Have a joint cavity and fibrous connective tissue • Example: Knee • Nonsynovial joints: • No joint cavity and fibrous connective tissue • Little or no movement • Example: Sutures of the skull Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Functions of Joints • Provide the bones a means to be manipulated, allowing for movement throughout segments of the body. • Provide stability, allowing for movement to take place without unwanted movement. • All joints in the human body are linked together; movement of one joint will directly affect the motion of others. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Joint Connective Tissue • Ligaments connect bone to bone and provide static and dynamic stability as well as proprioception. • Characterized by poor vascularity and do not repair or adapt as easily as other tissues in the body. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Weight-bearing Exercise Weight bearing exercise: • Exercise that forces the body to work against gravity: • Running, lifting weights, calisthenics are weight bearing • Swimming and cycling are not • Helps build and maintain bones, muscles, and connective tissues; burns lots of calories. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins The Muscular System • Muscles generate internal tension that, under the control of the nervous system, manipulates the bones of our body to produce movement. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Structure of Skeletal Muscle Muscle is the compilation of many individual muscle fibers neatly wrapped together with connective tissue to form bundles: • The first bundle is the actual muscle itself, wrapped by an outer layer of connective tissue called fascia; the inner layer immediately surrounding the muscle is called epimysium. • The next bundle of muscle fiber is a fascicle that is wrapped by connective tissue called perimysium. • Each fascicle is made up of many individual muscle fibers that are wrapped by connective tissue called endomysium. • Each layer of connective tissue extends the length of the muscle, helping to form the tendon. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Connective Tissue • Tendons are the structures that attach muscles to bone and provide the anchor from which the muscle can exert force and control the bone and joint. • They have poor vascularity (blood supply), which leaves them susceptible to slower repair and adaptation. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Muscle Fibers • Contain typical cell components: • Cellular plasma called sarcoplasm (contains glycogen, fats, minerals, and oxygen-binding myoglobin) • Nuclei • Mitochondria (transform energy from food into energy for the cell) • Unlike typical cells, they also have structures called myofibrils. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Contractile Elements • Myofibrils contain myofilaments that are the actual contractile components of muscle tissue: • • Actin Myosin • Actin (thin) and myosin (thick) filaments form sections known as a sarcomere. • A sarcomere is the functional unit of the muscle, much like the neuron is for the nervous system: • It lies in the space between two Z lines; each Z line denotes another sarcomere along the myofibril. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Contractile Elements • Two protein structures that are also important to muscle contraction are tropomyosin and troponin. • Tropomyosin is located on the actin filament and blocks myosin binding sites located on the actin filament, keeping myosin from attaching to actin while the muscle is in a relaxed state. • Troponin, also located on the actin filament, plays a role in muscle contraction by providing binding sites for both calcium and tropomyosin when a muscle needs to contract. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Troponin Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Generating Force in a Muscle Neural activation: • Essential for a muscle to manipulate force for either movement or stabilization. • Generated by the communication between the nervous system and the muscular system or the motor unit (motor neuron and the muscle fibers with which it connects). Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Neural Activation 1. 2. 3. 4. 5. 6. Electrical impulses are transported from the CNS down the axon of the neuron. When the impulse reaches the end of the axon (axon terminal), chemicals called neurotransmitters are released. Neurotransmitters (chemical messengers) cross the synapse between the neuron and muscle fiber, transporting the electrical impulse from the nerve to the muscle. The specific neurotransmitter used for muscle contraction is acetylcholine (ACh). ACh falls into receptor sites on the muscle fiber, specifically designed for its attachment. Once attached, ACh stimulates the muscle fibers to go through a series of steps that produce muscle contractions. Summation causes either all motor fibers of a unit to fire or none; this is the “all or nothing law.” Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Sliding Filament Theory The proposed process of how the contraction of the filaments within the sarcomere takes place: • A sarcomere shortens as a result of the Z lines moving closer together. • The Z lines converge as the result of myosin heads attaching to the actin filament and asynchronously pulling (power strokes) the actin filament across the myosin. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Excitation–Contraction Coupling • • • • • • A nerve impulse (action potential) is transmitted through the neuron and down the axon to where the axon meets the muscle fiber (neuromuscular junction) and releases ACh. ACh transports across the synapse and binds to its receptor on the muscle fiber. This continues the neural message (action potential) to the muscle fiber that triggers the release of calcium (Ca2+) into the sarcoplasm (where the actin and myosin are located). Ca2+ binds to the protein troponin, forcing the protein tropomyosin to move away from the myosin binding site and allowing for myosin to attach to actin. Myosin attaches to actin, creating a pull of the filaments across each other (sliding filament theory) and causing the muscle to shorten (contract). Once the neural impulse for contraction subsides, calcium concentration in the sarcoplasm decreases, forcing myosin to unbind with the actin, ending the muscle contraction. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Muscle Fiber Types • Type I: Slow Twitch • • • • • • Higher in capillaries, mitochondria, and myoglobin Increased oxygen delivery Smaller in size Produce less force Slow to fatigue Long-term contractions (stabilization) • Type II: Fast Twitch • • • • • • Lower in capillaries, mitochondria, and myoglobin Decreased oxygen delivery Larger in size Produce more force Quick to fatigue Short-term contractions (force and power) Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Muscle Fiber Arrangement Muscle Types and Fiber Arrangements Type Fiber Arrangement Example Fusiform Parallel to direction of tendon Biceps brachii Fan-shaped Diverges from broad attachment to narrow one Pectoralis major Longitudinal Parallel to line of pull Sartorius Quadrilateral Parallel to line of pull Rhomboid Unipenniform Oblique to line of pull Posterior tibialis Bipenniform Oblique to line of pull Rectus femoris Multipenniform Oblique to line of pull Deltoid Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Muscles As Movers • Agonist muscles act as prime movers: Gluteus maximus is an agonist for hip extension. • Synergist muscles assist prime movers during movement: Hamstring and the erector spinae are synergistic with the gluteus maximus during hip extension • Stabilizer muscles support or stabilize the body while the prime movers and the synergists perform the movement patterns: Transversus abdominis, internal oblique, and multifidus stabilize the low back, pelvis, and hips during hip extension. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Endocrine System System of glands that secrete hormones that control bodily function: • Consists of host organs, chemical messengers, target cells. • Target cells bind specifically to hormones. • Regulates body functions (growth, metabolism, and response to stress). Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Endocrine Glands Primary glands of the endocrine system include: • Pituitary “master” gland with anterior, posterior and intermediate globes • Hypothalamus • Thyroid gland • Adrenal gland Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Endocrine Glands Pituitary gland: • Master control gland has three lobes: • • • Anterior: Secretes growth hormone, prolactin, adrenocorticotropic hormone (adrenal glands) thyroid-stimulating hormone (thyroid), folliclestimulating hormone (sex organs) and luteinizing hormone (sex organs). Intermediate: Secretes melanocyte-stimulatinh hormone (skin). Posterior: Secretes vasopressin (fluid retention) and oxytocin (childbirth). Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Endocrine Glands • Thyroid gland: Regulates metabolism. • Adrenal glands: “Fight-or-flight” hormones and inflammation (epinephrine “adrenaline” and norepinephrine). • Testosterone is produced in testes and adrenal glands; men produce 10 times more than women. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Blood Glucose Control • Control of blood glucose levels regulated by the pancreas to prevent wide swings in blood glucose levels. • Insulin: Brings glucose into cells from blood stream, resulting in net drop in blood sugar levels. • Glucagon: Signals the liver and muscles to break down and release glycogen stores; results in net rise of blood sugar levels. • Exercise improves body’s utilization of glucose. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins The Effects of Exercise • Epinephrine is released during exercise, which increases heart rate, elevates blood glucose, and opens airways. • Exercise is response to “flight-or-fight” mechanism. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Hormones • Both produced by men and women – Testosterone-men produce 10 times more is produced in testes and adrenal glands, major anabolic agent – Estrogen-produced in ovaries and adrenal glands, women produce significantly more – Cortisol produced in adrenal is main catabolic agent – Growth Hormone-produced in pituitary major anabolic agent – Thyroid-Found in in neck, controls metabolism – Exercise can elevate all these hormones Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Summary • The three components of the kinetic chain (nervous, muscular, and skeletal systems) all work together to produce movement. • The nervous system is composed of billions of neurons that transfer information throughout the body, through two interdependent systems: the CNS and the PNS. • The skeletal system is the body’s framework and is made up of bones and joints in two divisions: axial and appendicular. • The muscular system is made up of many individual fibers attached to bones by way of the tendons. Muscles generate force through neural activation, the sliding filament theory, and excitation–contraction coupling. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins