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Neuroscience for the Study of
Communicative Disorders, 3e
Chapter 3: Internal Anatomy of the Central Nervous
System
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Learning Objectives
• Identify shapes of corticospinal fibers at different neuraxial levels
• Recognize the ventricular cavity at various neuraxial levels
• Recognize major internal anatomic structures of the spinal cord and describe their
functions
• Recognize important internal anatomic structures of the medulla and explain their
functions
• Recognize important internal anatomic structures of the pons and describe their
functions
• Identify important internal anatomic structures of the midbrain and discuss their
functions
• Recognize important internal anatomic structures of the forebrain (diencephalon,
basal ganglia, and limbic structures) and describe their functions
• Follow the continuation of major anatomic structures and relate them in each
sequential section of the brain
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Anatomic Orientation Landmarks
• Shapes of Corticospinal Fibers
• Shape of Ventricular Cavity
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Spinal Cord in Cross-Sections
• Sacral Section
• Lumbar Section
• Thoracic Section
• Cervical Section
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Brainstem in Transverse Sections
• Medulla Oblongata
– Caudal Medulla
– Lower (Caudal) Third of Medulla
– Middle Third of Medulla
– Rostral Third of Medulla
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Brainstem in Transverse Sections - continued
• Pons
– Lower Pons
– Middle Pons
– Pontomidbrain Junction
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Brainstem in Transverse Sections - continued
• Midbrain
– Caudal Midbrain
– Rostral Midbrain
– High Rostral Midbrain
• Midbrain–Diencephalon Junction
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Forebrain in Coronal Sections
• Coronal Section Through Posterior Thalamus
• Coronal Section Through Midthalamus
• Coronal Section Through Anterior Thalamus
• Coronal Section Through Anterior Commissure
• Coronal Section Through Anterior Limb of Internal Capsule
and Caudate Head
• Coronal Section Through Anterior Horn
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Summary
• Knowledge of the internal brain anatomy is the most important
part of training in neuroscience and is essential for solving
clinical problems. It is learned best by repeated studying of
internal structures on the serial sections of the spinal cord,
brainstem, and forebrain, and by relating structures to their
functions. Visual orientation to structures as well as functional
knowledge of internal anatomy are essential and are the basis
for overall understanding of brain structures and their relation
to clinical symptoms.
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Technical Terms
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amygdaloid nucleus
anterior medullary velum
caudate nucleus
central gray
cerebral aqueduct
choroid plexus
cingulate gyrus
collateral trigone
corona radiata
fornix
hippocampus (hippocampal
formation)
hypothalamus
inferior cerebellar peduncle (restiform
body)
inferior colliculus
insula (isle of Reil)
internal arcuate fibers
lateral geniculate body
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lateral lemniscus
medial geniculate body
medial lemniscus
medial longitudinal fasciculus
middle cerebellar peduncle (brachium pontis)
pineal
principal (inferior) olivary nucleus
pyramidal decussation
red nucleus
reticular formation
semiovale center
spinocerebellar tract
substantia nigra
subthalamic nucleus
superior cerebellar peduncle (brachium
conjunctivum)
superior colliculus
thalamus
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Quiz Questions
1. Define the following terms:
1. Cerebral aqueduct
2. Inferior colliculus
3. Lateral geniculate body
4. Medial geniculate body
5. Medial longitudinal fasciculus
6. Pyramidal decussation
7. Red nucleus
8. Substantia nigra
9. Subthalamic nucleus
10. Superior colliculus
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Quiz Questions-continued
2.
Identify three landmark structures of the internal
medulla and define their functions.
3.
What ventricular cavity is located dorsal to the pons?
4.
Identify three landmarks of the internal pons and
define their functions.
5.
What differentiates tectal and tegmental regions in
the midbrain?
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins
Quiz Questions-continued
6.
Name three major internal structures of the midbrain
and define their functions.
7.
List five structures that are present on a coronal
forebrain cut at the caudate head level and define their
functions.
8.
Explain why a hemorrhage in the right caudal medulla
involving the corticospinal fibers will cause a left
hemiplegia.
Copyright © 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins