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09/06/1509/06/2015 AN INOVIETIVE WAY TO IMITATE HUMAN TOUCH Table of contents Introduction.......................................................................................................................... 2 Literature review .................................................................................................................. 3 Project Goal .......................................................................................................................... 4 Project description ............................................................................................................... 4 Overall design& characterization ..................................................................................... 4 Method of fabrication ........................................................................................................ 6 Application ......................................................................................................................... 6 Conclusion and recommendations:...................................................................................... 8 Reference .............................................................................................................................. 9 Abstract Human skin is a remarkable organ. It consists of an integrated, stretchable network of sensors allowing us to maneuver within our environment safely and effectively. Interest in large-area networks of electronic devices inspired by human skin is the motivation to creating electronic skin for medical diagnostics, among other applications. E-skin, an electronic skin device is an electronic network that form flexible and stretchable devices who is compatible with large-area implementation and integrated with multiple functionalities to imitate human touch. Furthermore, e-skin has developed to be a sensitive device that is able to sense objects that the human touch sense cannot. E-skins are already capable of providing increased performance in all life aspect, from innovative technology, many smartphone function can been done from a fingertip with an e-skin device implementation and it goes further to the health care filed to discover cancer. Those devices could be further improve through the innovative research and in the near Future additional functionalities can be preform via e-skin devices. 1 Introduction Human skin is the most visible and complex part of our body and even though it is easy to neglect the complexity of the largest sensory organ in our bodies. Our skin is the physical barrier through which we interact with our surroundings, allowing us to perceive various shapes and textures, changes in temperature, and varying degrees of contact pressure. To achieve such high sophistication in its sensing capabilities, several different types of highly specialized sense receptors are embed within our skin. These receptors first transduce information generated by physical contact into electrical signals and subsequently send it to the central nervous systems for more complex processing. All those signals are interpret by our brain so we successfully navigate in our physical world with ease. The effort to create an artificial skin with human-like sensory capabilities is motivate by the possibility of such large, multi-sensory surfaces being highly applicable for medical diagnostics. Sensor skins applied on or in the body could provide an unprecedented level of diagnostic and monitoring capabilities. The electronic skin is able to determine tumors at sizes four times smaller than can be detected by the most skilled health care provider during physical examination. One example of the benefits that human race can gain of this type of sensor is the detection of small cancerous growths like breast cancer. Breast cancer is the most common cancer in women worldwide. Studies have proved that early detection is the key to breast cancer survival. In addition, the smaller the tumor when discovered, the better the chance it has not spread nearby tissue. Now a days doctors use clinical test and other simulation tests like mammogram or MRI to detect lumps but as trained and gifted the doctors will be they cannot usually detect lumps smaller than 21mm while examine a patient. For clarification, the American Cancer Society published that a 94% survival rate is possible if the tumor will be detect at less than 10mm. Those facts demonstrate the importance of a device that will be able to detect tumors as tiny as possible and hence the highly importance of e-skin devices development. 2 Literature review "Imperceptible magneto-electronics" by Michael Melzer, Martin Kaltenbrunner, Denys Makarov, Dmitriy Karnaushenko, Daniil Karnaushenko, Tsuyoshi Sekitani, Takao Someya & Oliver G. Schmidt), in this article the author specifically the Future electronic skin characteristics that aims to mimic the original skin in both functionality and appearance. Although some of the multifaceted properties of human skin may remain exclusive to the biological system, electronics opens a unique path that leads beyond imitation and could equip us with unfamiliar senses. In addition, the article demonstrate giant magneto resistive sensor foils with high sensitivity, unmatched flexibility and mechanical endurance. "Human touch" by Leslie Reed, in this article the author describe how nanoparticle sensor could improve breast cancer detection. This paper shows a more specific research in the e-skin field by scientists from NebraskaLincoln University, Saraf and Nguyen. In their research, they developed a nanoparticlebased device that emulates human touch and when pressed against the skin creates changes in electrical current that can be capture by a high-quality digital camera. The nanoparticle film, just one-60th the thickness of a human hair, is a sort of "electronic skin" able to sense texture and relative stiffness. The model can successfully detect tumors as small as 5 millimeters, hidden up to 20 millimeters deep. This technology allow improved detection for skin cancer and could significantly enhance clinical breast exams for early detection of cancer. " Paper-thin e-skin responds to touch " by Sarah Yang from the Media Relations department on Berkley university review the research of a team led by Ali Javey, associate professor of electrical engineering and computer sciences and UC Berkeley coauthors on this study: David Hwang, Zhibin Yu and Kuniharu Takei. This research holds promise for sensory robotics and interactive environments and include the details for the first user-interactive sensor network on flexible plastic. The e-skin, responds to touch by instantly lighting up, the more intense the pressure, the brighter the light it emits. Furthermore, it explained the main approach for fabrication and characterization required. 3 Project Goal Innovative sensing tools have been development that make use of nanotechnology to detect and monitor various elements in personal or professional life. It opens up the possibilities for infinite innovative applications, starting from diagnosis and treatments of diseases, continuing with quality control of goods and environmental aspects, and ending with monitoring security issues. A fascinating idea is the possibility to imitate the human senses by means of nanotechnology and nanoscale sensors. For example, artificial skin with human-like sensory capabilities being highly applicable for medical diagnostics is a breakthrough in cancer early discovery. The main goal of making an electronic skin is that it can "feel" and images small lumps that fingers can miss. Knowing the size and shape of a lump could allow for earlier identification of cancer, which could save lives. The electronic skin is able to determine tumors at sizes four times smaller than can be detected by the most skilled health care provider during physical examination. Another great advantage of the device is its ability to record the images so that they will be included in the patient’s medical records and that it provides results right away. Project description Overall design& characterization Human skin is the inspiration for artificial skin systems. Artificial skin, also known as e-skin imitate skin function but should be much more sensitive to discover and sense elements that the human skin cannot. For this demand to be completed e-skin design should consist a fully research for all the materials- nanoparticles and polymers that will be used in the fabrication. The research that should consist the materials mechanical properties to ensure that they are similar to the properties of human skin (e.g. flexibility and stretch ability). Equally important is the ability of human skin to cure itself, artificial skin should be able to do the 4 same with at least equal or higher quality, allowing it to last a lifetime. Other desirable properties, including biocompatibility and biodegradability, self-healing and temperature sensitivity. To achieve these properties, the choice of materials is critical, and technological advancements in e-skin have been largely possible through the development of new materials and processing methods for the fabrication of stretchable and flexible devices. In addition, good electrical performance and compatibility with large-area processing techniques are important to create highly functional, low-cost devices. Nanomaterials often provide an advantageous combination of physical properties and cost. The e-skin also need to be durable for all kind of forces such as normal, shear and bending as illustrating in the picture below: Another factor that need to be revise is developing e-skin hardware, who its true value is derive from effective digitization, which requires software to provide a communication interface with the user. The signals produced from sensors in e-skins are analog, and signal digitization is required for interfacing with modern digital microprocessors. Ideally, digitization would be a process that does not require considerable power consumption. After digitization, software algorithms need to process and interpret the large amounts of data. 5 Method of fabrication Following from the demands above E-skin should be a network of mechanically flexible sensors that can be wear or implement. A thin and interactive sensor network that will be able to arrange in a layered form on a surfaces of virtually any shape. The device should give out immediate feedback when touched. A research team at Berkeley University have created a matrix of interactive pressure sensors that response to touch with light, the intensity of the light is proportional to the pressure. Unlike a stiff iPhone touchscreen, this system is highly flexible and can be easily laminated onto any surface, no matter how geometrically complex. The fabrication consist of a thin layer of polymer on top of a silicon wafer and then used standard semiconductor manufacturing techniques to layer in a transistor, an organic LED and a pressure sensor on top of each other. Finally, they simply peeled off the plastic from the silicon base, leaving a freestanding film with a sensor network embedded in it. Their result was a matrix of 16 by 16 sensors that is highly interactive with a response time of just one millisecond. Application The main purpose of e-skin is to make life easier and more comfortable as possible just like the main purpose of Nano sensors in general; e-skin can be a great use for medical devices in multiple areas and especially in the cancer discover field since this area demand accuracy above all things. 6 Ravi Saraf and Chieu Van Nguyen, scientists at the University of Nebraska, have suggested an innovative design for e- skin. They have created an electronic skin that can detect lumps as small as 5mm and as deep as 20mm into the tissue. The electronic skin device, which is about 150nm thick, has many layers comprised of nanoparticles and polymers. It is fabricated layer-by-layer using the following polymers: PAH and PSS to create a thin-film tool. Their research is a significant breakthrough, early detection of breast cancer could save the lives of many people because it is a known fact that early detection of cancer and especially breast cancer is among the most important factors for survival. The electronic skin is able to determine tumors at sizes four times smaller than can be detected by the most skilled health care provider during physical examination. An illustration shown in the image below: The device held against the skin, capture an image with a high-resolution camera, an image of the tissue that show any abnormalities. The device has been optimized for sensitivity in order to provide high quality images without the need for uncomfortable pressure on the breast so the patient will feel as comfortable as possible, a very important factor to consider because breast test is an inconvenient situation as it is. According to Saraf and Nguyen the team is now building the first prototype of the device, it will take about a year to build and cost an estimated $1.5 million. 7 Conclusion and recommendations: E-skin development has accelerated dramatically in the past few years since new materials and processes has developed. This progress e-skin functions are rapidly converging with those shown in science fiction movies. e-skin design require a lot of different aspect, it begin with the materials that need to be choose in a way to ensure all demands are fulfill, the structure should be well designed and another important factor is the data analyzer that need to consist a solid and reliable software. As described e-skin is an important tool that can contribute a lot to the population of the world in all kind of field and especially in the health care area. The rapid pace of progress in e-skin technology suggests that the fabrication of a more complex e-skin with progress properties will soon be possible. Nonetheless, the road of developing a practical e-skin for all is not short. Now it is a high cost technology and not accessible for the majority hence it is crucial to keep investigate and research for a low cost materials that fulfill all requirements. Furthermore, society in general and the science community in particular souled raise the awareness on this innovative field because it is certain to be a great thing to humanity. In conclusion, e-skin devices will be a great news to all people worldwide, it will save many lives and improve life beyond recognition, since the main propose of sensors is to make life easier, e-skin is an important news on the Nano sensors field. 8 Reference Melzer, M., Kaltenbrunner, M., Makarov, D., Karnaushenko, D., Karnaushenko, D.& Sekitani, T. (n.d.). Imperceptible magnetoelectronics. NATURE COMMUNICATIONS. Retrieved January 21, 2015, From http://www.nature.com/ncomms/2015/150121/ncomms7080/full/ncomms7080.html Chieu Van Nguyen and Ravi F. Saraf Department of Chemical and Bimolecular Engineering, Nebraska Center for Materials and Nanoscience, University of Nebraska—Lincoln. Publication Date (Web): August 22, 2014. American Chemical Society http://pubs.acs.org/doi/abs/10.1021/am5046789 Leslie Reed. "'Human Touch' Nanoparticle Sensor Could Improve Breast Cancer Detection." 'Human Touch' Nanoparticle Sensor Could Improve Breast Cancer Detection. University of Nebraska-Lincoln, 11 Sept. 2014. Yang, Sarah. "Paper-thin E-skin Responds to Touch, Holds Promise for Sensory Robotics and Interactive Environments." UC Berkeley News Center. Media Relations, 21 July 2014 "New 'electronic Skin' for Prosthetics, Robotics Detects Pressure from Different Directions." New 'electronic Skin' for Prosthetics, Robotics Detects Pressure from Different Directions. Phys.org, 10 Dec. 2014 9