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9.1 Cellular Respiration Feel the Burn • Do you like to bike, run, or swim? These are good ways to exercise. When you exercise, your body uses O2 to get energy from glucose, a 6-carbon sugar. • 1. How does your body feel at the start of exercise, such as a long, slow run? How do you feel 1 min. into the run? 10 min. into the run? • 2. What do you think is happening in your cells to cause the changes in how you feel? • 3. Think about running as fast as you can for a 100 meter run. Could you keep this pace for a long distance? Explain. A. Chemical Energy and Food • 1 gram of glucose releases 3811 calories. • A calorie-amount of heat energy required to raise the temperature of 1 gram of water 1 degree Celcius. • A Calorie-Kilocalorie=1000 calories – (food labels) B. Overview of Cellular Respiration • Glycolysis, the Krebs cycle, and the electron transport chain make up a process called CELLULAR RESPIRATION • Cellular Respiration is a process that releases energy by breaking down food molecules in the presence of oxygen. Equation for Cellular Respiration • C6H12O6 + 6O2 → 6CO2 + 6H2O + energy • Remind you of anything??? Cellular Respiration • Requires oxygen (aerobic) • Breaks down food to release energy • C6H12O6 + 6O2 → 6CO2 + 6H2O + energy • So what is the food that is being broken down??? Where C.R. takes place • Cellular Respiration takes place in the mitochondria. – 1st reaction takes place in the inner membrane – 2nd reaction in the inner-inner “coils” membrane Makes 34 ATPs FIRST STEP • The first step of cellular respiration is glycolysis. • Glycolysis-produces 2 molecules of pyruvic acid, 2 molecules of ATP, and 2 molecules of NADH. C. Glycolysis • • • • Breaks down glucose Does NOT require oxygen (anaerobic) Takes place in the cytoplasm 6-carbon sugar is split into a 3 carbon PGAL molecule. (2 ATP’s are used here) • 4 molecules of ADP are built up to ATP • -2 ATP(start)+4 ATP(made)=2 ATP net total D. Fermentation • An anaerobic process (doesn’t require oxygen) Alcoholic Fermentation • Pyruvic Acid is broken down to produce 2 carbon alcohol and CO2 • Bakers and brewers • Dough to rise (air spaces in bread) • CO2 released by fermentation=bubbles in beers or wine • When alcohol reaches 12%, yeast cells die. Alcolholic Fermentation Lactic Acid Fermentation • Pyruvic Acid accumulates as a result of glycolysis converted to lactic acid • Lactic acid produced in muscles during rapid exercise when body cannot supply enough O2 to the tissue to produce all ATP required • Burning, painful a few sec. after exercise • Large muscles cannot get enough oxygen Lactic Acid Fermentation • • • • What to do to help??? Stretch Drink lots of water Don’t forget to breath! Glycolysis pathways • At the end of glycolysis about 90% of the chemical NRG in glucose was not used. • Cells get that energy by using OXYGEN. • If oxygen IS present…glycolysis will go into cellular respiration. 9.2 The Krebs Cycle and Electron Transport • 1. Kreb Cycle -1st step in respiration (inner membrane of mitochondria) breaks down carbs, proteins, and lipids. • 2. Electron Transport- H+ and O-2 form H2O. ADP to ATP. • 3. ATP Formation -different charges release NRG in the form of ATP. The TOTALS of ATP • Glycolysis • Respiration » 2 ATP 34 ATP 36 ATP Exercise and Energy • Anaerobic (gycolysis) only last a short period. • Once runner is at 50 meter mark almost all ATP is gone~90 sec. • Fermentation builds up (lactic acid) need to replenish body with breathing. • What if race is longer than 90 sec.? This is what happens… • Cellular respiration will pick up the pace and continue the supply of ATP. • Muscles and other body parts store NRG (last 15-20 min.) after that your body burns stored molecules…FATS. • Body uses NRG to release heat when we exercise. Conserves heat in winter to stay warm. In Summary • Glycolysis has two choices: • If O2 is present glycolysis will go into cellular respiration to supply body with oxygen and ATP • If O2 is NOT present then glycolysis will go into the fermentation process.