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Curriculum Vitae Name Fragiskos I. Parthenakis Place of Birth Crete, Greece Date of Birth 22 -4 -1954 Marital Status Married with two children. Present Position Associate Professor of Cardiology at the Faculty of Medicine of the University of Crete Medical Education Medical Degree, Aristotle University of Thessaloniki (1981) Specialization Internal Medicine (1986), Heraklion Venizeleion Hospital Cardiology (1989), Heraklion Venizeleion Hospital, 417 VA Hospital (NIMTS), Athens Post Graduate Studies Ph.D. Cardiology, University of Crete (1990-1994) Research Fellow in Cardiology, Hammersmith Hospital, London UK (1993-1994) Scientific Distinctions Fellow of the European Society of Cardiology (FESC) Member of the European Society of Echocardiography Member of the European Heart Rhythm Association Member of the European Association of Prevention and Rehabilitation Member of the Hellenic Society of Cardiology President elected of the Hellenic working group of Echocardiography Counsellor of the Hellenic Cardiovascular Research Society Page 1 of 11 Publications Fragiskos Parthenakis has published 86 peer-reviewed research papers (PubMed database). Collectively, he has 102 cited documents (Scopus database), which have received 1078 citations and resulted in an h index of 20 (updated on 5th of February 2014). The peer-reviewed publications are listed below in chronological order. 2014 1. Marketou, M.E., J. Kontaraki, E. Zacharis, F. Parthenakis, S. Maragkoudakis, I. Gavras, H. Gavras, and P.E. Vardas, Differential gene expression of bradykinin receptors 1 and 2 in peripheral monocytes from patients with essential hypertension. J Hum Hypertens, 2014. 2013 2. Patrianakos, A.P., E. Nyktari, F.I. Parthenakis, and P.E. Vardas, Reversible left ventricular apical ballooning after heavy alcohol consumption in a patient with hypertrophic cardiomyopathy. Int J Cardiol, 2013. 164(3): p. e29-31. 3. Marketou, M.E., E.A. Zacharis, F. Parthenakis, G.E. Kochiadakis, S. Maragkoudakis, G. Chlouverakis, and P.E. Vardas, Association of sodium and potassium intake with ventricular arrhythmic burden in patients with essential hypertension. J Am Soc Hypertens, 2013. 7(4): p. 276-82. 4. Kontaraki, J.E., M.E. Marketou, E.A. Zacharis, F.I. Parthenakis, and P.E. Vardas, Differential expression of vascular smooth muscle-modulating microRNAs in human peripheral blood mononuclear cells: novel targets in essential hypertension. J Hum Hypertens, 2013. 2012 5. Patrianakos, A.P., N. Protonotarios, E. Nyktari, K. Pagonidis, A. Tsatsopoulou, F.I. Parthenakis, and P.E. Vardas, Arrhythmogenic right ventricular cardiomyopathy/dysplasia and troponin release. Myocarditis or the "hot phase" of the disease? Int J Cardiol, 2012. 157(2): p. e26-8. 6. Kochiadakis, G., M. Marketou, S. Koukouraki, F. Parthenakis, G. Chlouverakis, N. Karkavitsas, and P. Vardas, Cardiac autonomic disturbances in patients with vasovagal syndrome: comparison between iodine-123-metaiodobenzylguanidine myocardial scintigraphy and heart rate variability. Europace, 2012. 14(9): p. 1352-8. 7. Andrikopoulos, G., S. Pastromas, A. Kartalis, K. Toli, I. Mantas, S. Tzeis, C. Kyrpizidis, C. Olympios, A.J. Manolis, S. Foussas, A. Kranidis, A. Pras, A. Pipilis, D. Chryssos, A. Gotsis, A. Trikas, D. Richter, D. Alexopoulos, F. Parthenakis, G. Theodorakis, S. Konstantinides, and P. Vardas, Inadequate heart rate control is associated with worse quality of life in patients with coronary artery disease and chronic obstructive pulmonary disease. The RYTHMOS study. Hellenic J Cardiol, 2012. 53(2): p. 118-26. Page 2 of 11 2011 8. Parthenakis, F., A. Patrianakos, E. Nyktari, D. Arfanakis, E. Zacharis, and P. Vardas, Prognostic value of NT-pro BNP, left ventricular inotropic reserve and cardiopulmonary exercise test in patients with non-ischemic dilated cardiomyopathy. Int J Cardiol, 2011. 147(2): p. 326-8. 9. Marketou, M.E., J.E. Kontaraki, N.A. Tsakountakis, E.A. Zacharis, G.E. Kochiadakis, D.A. Arfanakis, F. Parthenakis, G. Chlouverakis, and P.E. Vardas, Differential effect of telmisartan and amlodipine on monocyte chemoattractant protein-1 and peroxisome proliferator-activated receptor-gamma gene expression in peripheral monocytes in patients with essential hypertension. Am J Cardiol, 2011. 107(1): p. 59-63. 10. Kontaraki, J.E., M.E. Marketou, E.A. Zacharis, F.I. Parthenakis, and P.E. Vardas, Early cardiac gene transcript levels in peripheral blood mononuclear cells in patients with untreated essential hypertension. J Hypertens, 2011. 29(4): p. 791-7. 2010 11. Patrianakos, A.P., N. Protonotarios, A. Zacharaki, A. Tsatsopoulou, F.I. Parthenakis, and P.E. Vardas, Isolated left ventricular apical hypoplasia: a newly recognized unclassified cardiomyopathy. J Am Soc Echocardiogr, 2010. 23(12): p. 1336 e1-4. 12. Parthenakis, F., E. Koutalas, A. Patrianakos, M. Koukouvas, E. Nyktari, and P. Vardas, Diagnosing acute aortic syndromes: the role of specific biochemical markers. Int J Cardiol, 2010. 145(1): p. 3-8. 13. Marketou, M., A. Patrianakos, F. Parthenakis, E. Zacharis, D. Arfanakis, G. Kochiadakis, G. Chlouverakis, and P. Vardas, Systemic blood pressure profile in hypertensive patients with low hemoglobin concentrations. Int J Cardiol, 2010. 142(1): p. 95-6. 14. Kontaraki, J.E., F.I. Parthenakis, E.G. Nyktari, A.P. Patrianakos, and P.E. Vardas, Myocardial gene expression alterations in peripheral blood mononuclear cells of patients with idiopathic dilated cardiomyopathy. Eur J Heart Fail, 2010. 12(6): p. 541-8. 2009 15. Zacharaki, A.A., A.P. Patrianakos, F.I. Parthenakis, and P.E. Vardas, Quadricuspid aortic valve associated with non-obstructive sub-aortic membrane: a case report and review of the literature. Hellenic J Cardiol, 2009. 50(6): p. 544-7. 16. Patrianakos, A.P., F.I. Parthenakis, E. Nyktari, N. Malliaraki, D.N. Karakitsos, and P.E. Vardas, Central aortic stiffness in patients with nonischemic dilated cardiomyopathy: relationship with neurohumoral activation. J Card Fail, 2009. 15(8): p. 665-72. Page 3 of 11 17. Patrianakos, A.P., F.I. Parthenakis, D. Karakitsos, E. Nyktari, and P.E. Vardas, Proximal aortic stiffness is related to left ventricular function and exercise capacity in patients with dilated cardiomyopathy. Eur J Echocardiogr, 2009. 10(3): p. 425-32. 18. Parthenakis, F., E. Nyktari, A. Patrianakos, A. Pitsis, A. Asimaki, and P. Vardas, Asymptomatic papillary fibroelastoma of the aortic valve in a young woman - a case report. Cardiovasc Ultrasound, 2009. 7: p. 43. 19. Hassoulas, J., A.P. Patrianakos, F.I. Parthenakis, and P.E. Vardas, Prosthetic aortic valve endocarditis complicated with annular abscess, sub-aortic obstruction and valve dehiscence. Hellenic J Cardiol, 2009. 50(4): p. 319-23. 2008 20. Pitsis, A.A., A.N. Visouli, T.G. Kelpis, V.N. Ninios, N. Nikoloudakis, F. Parthenakis, and P. Vardas, Diverticulum of the left ventricle: etiology and surgical treatment. Heart Surg Forum, 2008. 11(2): p. E757. 21. Patrianakos, A.P., F.I. Parthenakis, E.G. Nyktari, and P.E. Vardas, Noncompaction myocardium imaging with multiple echocardiographic modalities. Echocardiography, 2008. 25(8): p. 898-900. 22. Patrianakos, A.P., F.I. Parthenakis, E. Nyktari, G.E. Kochiadakis, A.V. Koutsopoulos, and P.E. Vardas, Right atrial myxoma: echocardiographic appearance. Eur J Echocardiogr, 2008. 9(3): p. 422-3. 23. Patrianakos, A.P., F.I. Parthenakis, D.M. Karakitsos, and P.E. Vardas, Echocardiographic assessment of proximal aorta pulse wave velocity. J Am Soc Echocardiogr, 2008. 21(4): p. 404. 24. Parthenakis, F.I., A.P. Patrianakos, E.N. Simantirakis, and P.E. Vardas, CRT and exercise capacity in heart failure: the impact of mitral valve regurgitation. Europace, 2008. 10 Suppl 3: p. iii96-100. 25. Parthenakis, F.I., A.P. Patrianakos, C.N. Haritakis, E.A. Zacharis, E.G. Nyktari, and P.E. Vardas, NTproBNP response to dobutamine stress echocardiography predicts left ventricular contractile reserve in dilated cardiomyopathy. Eur J Heart Fail, 2008. 10(5): p. 475-81. 26. Kontaraki, J.E., F.I. Parthenakis, A.P. Patrianakos, I.K. Karalis, and P.E. Vardas, Myocardin gene regulatory variants as surrogate markers of cardiac hypertrophy - study in a genetically homogeneous population. Clin Genet, 2008. 73(1): p. 71-8. 27. Diakakis, G.F., F.I. Parthenakis, A.P. Patrianakos, S.I. Koukouraki, M.I. Stathaki, N.S. Karkavitsas, and P.E. Vardas, Myocardial sympathetic innervation in patients with impaired glucose tolerance: relationship to subclinical inflammation. Cardiovasc Pathol, 2008. 17(3): p. 172-7. Page 4 of 11 2007 28. Skalidis, E.I., M.I. Hamilos, G. Chlouverakis, G.E. Kochiadakis, F.I. Parthenakis, and P.E. Vardas, Acute effect of esmolol intravenously on coronary microcirculation in patients with idiopathic dilated cardiomyopathy. Am J Cardiol, 2007. 100(8): p. 1299-302. 29. Patrianakos, A.P., F.I. Parthenakis, D. Karakitsos, E. De Groot, E.A. Skalidis, E. Nyktari, E. Daphnis, and P.E. Vardas, Relation of proximal aorta stiffness to left ventricular diastolic function in patients with end-stage renal disease. J Am Soc Echocardiogr, 2007. 20(3): p. 314-23. 30. Patrianakos, A.P., F.I. Parthenakis, I. Drositis, E. Nyktari, and P.E. Vardas, Primary heart angiosarcoma. Hellenic J Cardiol, 2007. 48(6): p. 364-5. 31. Parthenakis, F.I., A.P. Patrianakos, E.I. Skalidis, G.F. Diakakis, E.A. Zacharis, G. Chlouverakis, I.K. Karalis, and P.E. Vardas, Atrial fibrillation is associated with increased neurohumoral activation and reduced exercise tolerance in patients with non-ischemic dilated cardiomyopathy. Int J Cardiol, 2007. 118(2): p. 206-14. 32. Parthenakis, F.I., A.P. Patrianakos, K. Pagonidis, D.A. Arfanakis, A. Karantanas, and P.E. Vardas, Arrhythmogenic right ventricular cardiomyopathy: echocardiographic and magnetic resonance imaging in a patient presenting with ventricular tachycardia. J Am Soc Echocardiogr, 2007. 20(11): p. 1319 e7-10. 33. Nyktari, E., A.P. Patrianakos, F.I. Parthenakis, A. Koutsopoulos, and P.E. Vardas, Carcinoid heart disease in a patient with primary ovarian carcinoid tumour. Hellenic J Cardiol, 2007. 48(4): p. 234-5. 34. Kontaraki, J.E., F.I. Parthenakis, A.P. Patrianakos, I.K. Karalis, and P.E. Vardas, Altered expression of early cardiac marker genes in circulating cells of patients with hypertrophic cardiomyopathy. Cardiovasc Pathol, 2007. 16(6): p. 329-35. 35. Karakitsos, D., A.P. Patrianakos, F.I. Parthenakis, N. Malliaraki, D. Nikitovic, J. Kyriazis, A. Karabinis, J.W. Groothoff, E. de Groot, C. Fourtounas, E. Daphnis, and P.E. Vardas, Altered proximal aortic stiffness and endothelin plasma levels in diabetic patients with end-stage renal disease. ASAIO J, 2007. 53(3): p. 343-50. 36. Badano, L.P., O. Gaddi, C. Peraldo, G. Lupi, M. Sitges, F. Parthenakis, S. Molteni, M.R. Pagliuca, B. Sassone, P. Di Stefano, T. De Santo, C. Menozzi, and M. Brignole, Left ventricular electromechanical delay in patients with heart failure and normal QRS duration and in patients with right and left bundle branch block. Europace, 2007. 9(1): p. 41-7. 2006 37. Patrianakos, A.P., D. Karakitsos, E. de Groot, F.I. Parthenakis, E.K. Daphnis, and P.E. Vardas, Alteration of proximal aorta biophysical properties in patients with end stage renal disease. Heart, 2006. 92(2): p. 228-32. Page 5 of 11 38. Parthenakis, F.I., A.P. Patrianakos, S.K. Anagnostopoulos, P.K. Kafarakis, G.M. Lyrarakis, and P.E. Vardas, Bacterial endocarditis of the mitral valve with dual location. Hellenic J Cardiol, 2006. 47(6): p. 366-7. 39. Marketou, M.E., E.A. Zacharis, D. Nikitovic, E.S. Ganotakis, F.I. Parthenakis, N. Maliaraki, and P.E. Vardas, Early effects of simvastatin versus atorvastatin on oxidative stress and proinflammatory cytokines in hyperlipidemic subjects. Angiology, 2006. 57(2): p. 211-8. 40. Lupi, G., B. Sassone, L. Badano, C. Peraldo, O. Gaddi, M. Sitges, F. Parthenakis, S. Molteni, M.R. Pagliuca, N. Grovale, C. Menozzi, and M. Brignole, Effects of right ventricular pacing on intra-left ventricular electromechanical activation in patients with native narrow QRS. Am J Cardiol, 2006. 98(2): p. 219-22. 41. Karakitsos, D.N., A.P. Patrianakos, A. Paraskevopoulos, F.I. Parthenakis, N. Tzenakis, C. Fourtounas, E.K. Daphnis, and P.E. Vardas, Impedance cardiography derived cardiac output in hemodialysis patients: a study of reproducibility and comparison with echocardiography. Int J Artif Organs, 2006. 29(6): p. 564-72. 42. Karakitsos, D., A.P. Patrianakos, E. De Groot, J. Boletis, A. Karabinis, J. Kyriazis, G. Samonis, F.I. Parthenakis, P.E. Vardas, and E. Daphnis, Androgen deficiency and endothelial dysfunction in men with end-stage kidney disease receiving maintenance hemodialysis. Am J Nephrol, 2006. 26(6): p. 536-43. 43. Karakitsos, D., E. De Groot, A.P. Patrianakos, F. Parthenakis, J. Boletis, A. Karabinis, J. Kyriazis, P. Vardas, and E. Daphnis, Adiponectin and cardiovascular remodeling in end-stage renal disease and comorbid diabetes mellitus. Am J Nephrol, 2006. 26(4): p. 340-7. 44. Germanakis, I., M. Kalmanti, F. Parthenakis, D. Nikitovic, E. Stiakaki, A. Patrianakos, and P.E. Vardas, Correlation of plasma N-terminal pro-brain natriuretic peptide levels with left ventricle mass in children treated with anthracyclines. Int J Cardiol, 2006. 108(2): p. 212-5. 45. Germanakis, I., E. Galanakis, F. Parthenakis, P.E. Vardas, and M. Kalmanti, Clarithromycin treatment and QT prolongation in childhood. Acta Paediatr, 2006. 95(12): p. 1694-6. 2005 46. Patrianakos, A.P., F.I. Parthenakis, H.E. Mavrakis, E.A. Zacharis, and P.E. Vardas, Late left ventricular color M-mode Doppler in the assessment of diastolic dysfunction in patients with dilated cardiomyopathy. J Am Soc Echocardiogr, 2005. 18(9): p. 979. 47. Patrianakos, A.P., F.I. Parthenakis, H.E. Mavrakis, M. Saatsaki, G.F. Diakakis, G.I. Chlouverakis, and P.E. Vardas, Effects of Nebivolol on left ventricular function and exercise capacity in patients with non-ischaemic dilated cardiomyopathy. A randomised placebo-controlled study. Hellenic J Cardiol, 2005. 46(3): p. 199-207. Page 6 of 11 48. Patrianakos, A.P., F.I. Parthenakis, H.E. Mavrakis, G.F. Diakakis, G.I. Chlouverakis, and P.E. Vardas, Comparative efficacy of nebivolol versus carvedilol on left ventricular function and exercise capacity in patients with nonischemic dilated cardiomyopathy. A 12-month study. Am Heart J, 2005. 150(5): p. 985. 49. Patrianakos, A.P., F.I. Parthenakis, S.I. Chrysostomakis, and P.E. Vardas, Ventricular special defect in the elderly: an uncommon clinical entity. Hellenic J Cardiol, 2005. 46(2): p. 158-60. 50. Parthenakis, F.I., G.E. Kochiadakis, A.P. Patrianakos, M.I. Hamilos, I. Mitrouska, A.N. Katsamouris, and P.E. Vardas, Peripheral arterial embolism due to a left ventricular diverticulum in a young adult. Chest, 2005. 127(4): p. 1452-4. 51. Diakakis, G.F., F.I. Parthenakis, H.E. Mavrakis, A.P. Patrianakos, E.A. Zacharis, E.G. Nyktari, E.S. Ganotakis, and P.E. Vardas, Association of impaired glucose tolerance with increased heart rate and subclinical inflammation. Hellenic J Cardiol, 2005. 46(6): p. 394-401. 2004 52. Skalidis, E.I., F.I. Parthenakis, A.P. Patrianakos, M.I. Hamilos, and P.E. Vardas, Regional coronary flow and contractile reserve in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol, 2004. 44(10): p. 2027-32. 53. Patrianakos, A.P., F.I. Parthenakis, E.A. Papadimitriou, G.F. Diakakis, P.G. Tzerakis, D. Nikitovic, and P.E. Vardas, Restrictive filling pattern is associated with increased humoral activation and impaired exercise capacity in dilated cardiomyopathy. Eur J Heart Fail, 2004. 6(6): p. 735-43. 54. Parthenakis, F.I., A.P. Patrianakos, P.G. Tzerakis, D.M. Kambouraki, S.I. Chrysostomakis, and P.E. Vardas, Late left ventricular diastolic flow propagation velocity determined by color M-mode Doppler in the assessment of diastolic dysfunction. J Am Soc Echocardiogr, 2004. 17(2): p. 139-45. 2003 55. Parthenakis, F.I., A. Patrianakos, V. Prassopoulos, E. Papadimitriou, D. Nikitovic, N.S. Karkavitsas, and P.E. Vardas, Relation of cardiac sympathetic innervation to proinflammatory cytokine levels in patients with heart failure secondary to idiopathic dilated cardiomyopathy. Am J Cardiol, 2003. 91(10): p. 1190-4. 2002 56. Parthenakis, F.I., V.K. Prassopoulos, S.I. Koukouraki, E.A. Zacharis, G.F. Diakakis, N.K. Karkavitsas, and P.E. Vardas, Segmental pattern of myocardial sympathetic denervation in idiopathic dilated cardiomyopathy: relationship to regional wall motion and myocardial perfusion abnormalities. J Nucl Cardiol, 2002. 9(1): p. 15-22. 57. Parthenakis, F.I., M.K. Kanakaraki, E.M. Kanoupakis, E.I. Skalidis, G.F. Diakakis, O.K. Filippou, and P.E. Vardas, Value of Doppler index combining systolic and diastolic myocardial performance in Page 7 of 11 predicting cardiopulmonary exercise capacity in patients with congestive heart failure: effects of dobutamine. Chest, 2002. 121(6): p. 1935-41. 2001 58. Zouridakis, E.G., F.I. Parthenakis, G.E. Kochiadakis, E.M. Kanoupakis, and P.E. Vardas, QT dispersion in patients with mitral valve prolapse is related to the echocardiographic degree of the prolapse and mitral leaflet thickness. Europace, 2001. 3(4): p. 292-8. 59. Kochiadakis, G.E., E.I. Skalidis, M.D. Kaleboubas, N.E. Igoumenidis, M.I. Hamilos, F.I. Parthenakis, and P.E. Vardas, Effect of acute atrial fibrillation on coronary circulation. Am J Cardiol, 2001. 88(12): p. 1431-3, A8. 60. Kanoupakis, E., D. Michaloudis, O. Fraidakis, F. Parthenakis, P. Vardas, and J. Melissas, Left ventricular function and cardiopulmonary performance following surgical treatment of morbid obesity. Obes Surg, 2001. 11(5): p. 552-8. 61. Ikonomidis, I., A. Tsoukas, F. Parthenakis, A. Gournizakis, A. Kassimatis, L. Rallidis, and P. Nihoyannopoulos, Four year follow up of aortic valve replacement for isolated aortic stenosis: a link between reduction in pressure overload, regression of left ventricular hypertrophy, and diastolic function. Heart, 2001. 86(3): p. 309-16. 2000 62. Parthenakis, F.I., G.E. Kochiadakis, E.I. Skalidis, M.K. Kanakaraki, N.E. Mezilis, E.M. Kanoupakis, P.E. Vardas, and P. Nihoyannopoulos, Aortic atherosclerotic lesions in the thoracic aorta detected by multiplane transesophageal echocardiography as a predictor of coronary artery disease in elderly patients. Clin Cardiol, 2000. 23(10): p. 734-9. 63. Parthenakis, F.I., E.M. Kanoupakis, G.E. Kochiadakis, E.I. Skalidis, N.E. Mezilis, E.N. Simantirakis, M.K. Kanakaraki, and P.E. Vardas, Left ventricular diastolic filling pattern predicts cardiopulmonary determinants of functional capacity in patients with congestive heart failure. Am Heart J, 2000. 140(2): p. 338-44. 64. Parthenakis, F.I., M.K. Kanakaraki, and P.E. Vardas, Images in cardiology: silent patent ductus arteriosus endarteritis. Heart, 2000. 84(6): p. 619. 65. Mezilis, N.E., F.I. Parthenakis, M.K. Kanakaraki, M.E. Marketou, H.E. Mavrakis, and P.E. Vardas, Dobutamine- vs exercise-induced ST segment elevation early after Q wave myocardial infarction. Prediction of functional recovery after revascularization. Eur Heart J, 2000. 21(10): p. 814-22. 66. Kochiadakis, G.E., M.E. Marketou, N.E. Igoumenidis, E.N. Simantirakis, F.I. Parthenakis, E.G. Manios, and P.E. Vardas, Autonomic nervous system activity before and during episodes of myocardial ischemia in patients with stable coronary artery disease during daily life. Pacing Clin Electrophysiol, 2000. 23(12): p. 2030-9. Page 8 of 11 67. Kanoupakis, E.M., E.G. Manios, H.E. Mavrakis, M.D. Kaleboubas, F.I. Parthenakis, and P.E. Vardas, Relation of autonomic modulation to recurrence of atrial fibrillation following cardioversion. Am J Cardiol, 2000. 86(9): p. 954-8. 1999 68. Skalidis, E.I., F.I. Parthenakis, E.A. Zacharis, G.E. Datseris, and P.E. Vardas, Pulmonary tumor embolism from primary cardiac B-cell lymphoma. Chest, 1999. 116(5): p. 1489-90. 69. Skalidis, E.I., G.E. Kochiadakis, S.I. Koukouraki, F.I. Parthenakis, N.S. Karkavitsas, and P.E. Vardas, Phasic coronary flow pattern and flow reserve in patients with left bundle branch block and normal coronary arteries. J Am Coll Cardiol, 1999. 33(5): p. 1338-46. 70. Simantirakis, E.N., G.E. Kochiadakis, M.K. Kanakaraki, M.E. Marketou, F.I. Parthenakis, E.M. Kanoupakis, and P.E. Vardas, Impact of chronic DDD pacing on time-domain indexes of heart rate variability in patients with hypertrophic obstructive cardiomyopathy. Pacing Clin Electrophysiol, 1999. 22(12): p. 1808-13. 71. Parthenakis, F.I., E.I. Skalidis, G.E. Kochiadakis, E.A. Zacharis, C.S. Karidis, G.I. Chlouverakis, and P.E. Vardas, Assessment of left ventricular ejection dynamics in patients with coronary artery disease during dipyridamole-stress Doppler echocardiography. Coron Artery Dis, 1999. 10(7): p. 471-7. 72. Kochiadakis, G.E., N.E. Igoumenidis, F.I. Parthenakis, G.I. Chlouverakis, and P.E. Vardas, Amiodarone versus propafenone for conversion of chronic atrial fibrillation: results of a randomized, controlled study. J Am Coll Cardiol, 1999. 33(4): p. 966-71. 1998 73. Simantirakis, E.N., E.M. Kanoupakis, G.E. Kochiadakis, M.K. Kanakaraki, F.I. Parthenakis, E.G. Manios, E. Markianos, and P.E. Vardas, The effect of DDD pacing on ergospirometric parameters and neurohormonal activity in patients with hypertrophic obstructive cardiomyopathy. Pacing Clin Electrophysiol, 1998. 21(11 Pt 2): p. 2269-72. 74. Michaloudis, D., O. Fraidakis, A. Petrou, C. Gigourtsi, and F. Parthenakis, Anaesthesia and the QT interval. Effects of isoflurane and halothane in unpremedicated children. Anaesthesia, 1998. 53(5): p. 435-9. 75. Mezilis, N.E., F.I. Parthenakis, M.K. Kanakaraki, E.M. Kanoupakis, and P.E. Vardas, QT variability before and after episodes of nonsustained ventricular tachycardia in patients with hypertrophic cardiomyopathy. Pacing Clin Electrophysiol, 1998. 21(11 Pt 2): p. 2387-91. 76. Kochiadakis, G.E., N.E. Igoumenidis, M.C. Solomou, F.I. Parthenakis, M.G. Christakis-Hampsas, G.I. Chlouverakis, A.M. Tsatsakis, and P.E. Vardas, Conversion of atrial fibrillation to sinus rhythm using acute intravenous procainamide infusion. Cardiovasc Drugs Ther, 1998. 12(1): p. 75-81. Page 9 of 11 77. Kochiadakis, G.E., N.E. Igoumenidis, E.N. Simantirakis, M.E. Marketou, F.I. Parthenakis, N.E. Mezilis, and P.E. Vardas, Intravenous propafenone versus intravenous amiodarone in the management of atrial fibrillation of recent onset: a placebo-controlled study. Pacing Clin Electrophysiol, 1998. 21(11 Pt 2): p. 2475-9. 1997 78. Vardas, P.E., E.N. Simantirakis, F.I. Parthenakis, S.I. Chrysostomakis, E.I. Skalidis, and E.G. Zuridakis, AAIR versus DDDR pacing in patients with impaired sinus node chronotropy: an echocardiographic and cardiopulmonary study. Pacing Clin Electrophysiol, 1997. 20(7): p. 1762-8. 79. Simantirakis, E.N., F.I. Parthenakis, S.I. Chrysostomakis, E.G. Zuridakis, N.E. Igoumenidis, and P.E. Vardas, Left atrial appendage function during DDD and VVI pacing. Heart, 1997. 77(5): p. 428-31. 80. Parthenakis, F.I., K.S. Karidis, G. Zuridakis, E.M. Kanoupakis, G.I. Chlouverakis, and P.E. Vardas, Left ventricular diastolic filling changes during dipyridamole-induced ischaemia. An echo-Doppler study. Coron Artery Dis, 1997. 8(7): p. 449-54. 1996 81. Parthenakis, F.I., P.E. Vardas, L. Ralidis, A. Dritsas, and P. Nihoyannopoulos, QT interval in cardiac amyloidosis. Clin Cardiol, 1996. 19(1): p. 51-4. 82. Parthenakis, F., E. Skalidis, E. Simantirakis, D. Kounali, P. Vardas, and P. Nihoyannopoulos, Absence of atherosclerotic lesions in the thoracic aorta indicates absence of significant coronary artery disease. Am J Cardiol, 1996. 77(12): p. 1118-21 SERIALS SUBS JAF. 83. Parthenakis, F., G. Kochiadakis, E. Simantirakis, E. Zuridakis, S. Chrysostomakis, I. Ikonomidis, and P. Vardas, Incidence of ventricular arrhythmias during silent myocardial ischaemia in coronary artery disease. Int J Cardiol, 1996. 57(1): p. 61-7. 84. Kochiadakis, G.E., F.I. Parthenakis, E.G. Zuridakis, A.T. Rombola, S.I. Chrysostomakis, and P.E. Vardas, Is there increased sympathetic activity in patients with mitral valve prolapse? Pacing Clin Electrophysiol, 1996. 19(11 Pt 2): p. 1872-6. 1995 85. Simantirakis, E., E. Skalidis, F. Parthenakis, S. Chrysostomakis, E. Manios, G. Kochiadakis, and P. Vardas, Impact of atrioventricular delay on heart rate variability of paced patients with and without heart failure. Int J Cardiol, 1995. 52(3): p. 235-9. 1994 86. Vardas, P.E., E.N. Simandirakis, F.I. Parthenakis, E.G. Manios, N.G. Eleftherakis, and D.E. Terzakis, Study of late potentials and ventricular arrhythmias in hypertensive patients with normal electrocardiograms. Pacing Clin Electrophysiol, 1994. 17(4 Pt 1): p. 577-84. Page 10 of 11 Conferences Fragiskos Parthenakis has participated in numerous research conferences and has presented more than 150 conference proceedings. In numerous cases he has been an invited speaker or member/chair of the board committee. Furthermore, he is member of the organising committee of the Pulse and Cardioelectrics Meeting, taking place annually. Funding European funded projects: Title: TransPOT -Enhancing University of Crete Medical School Scientific Excellence and Translational Research Potential in Human Diseases Total Budget: 1500000 euros Source: European Union. Role in the research team: Collaborating investigator Starting/ending dates: 1/3/1012 – 31/12/2014 National funded projects: Fragiskos Parthenakis has awarded several research grands and awards from the Hellenic Society of Cardiology. Other funded projects are listed below. Title: Investigation of the levels of cardiovascular related microRNAs in peripheral blood cells of patients with cardiovascular diseases. Role in the research team: Principal investigator Budget: 1500 € Starting/ending dates: 18/1/2013 - 17/1/2014 Source: University of Crete Title: Cardiomyopathies in the population of Crete; Hypertrophic and dilated cardiomyopathies Role in the research team: Principal investigator Budget: 5000 € Starting/ending dates: 15/5/2013 - 14/5/2016 Source: Private funding Title: Participation in meetings Role in the research team: Principal investigator Budget: 1190 € Starting/ending dates: 1/5/2006 - 30/9/2007 Source: Private funding Page 11 of 11